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 TERMINÉ 

European Prevention of Alzheimer’s Dementia Consortium (EPAD)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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 40

 TERMINÉ 

Combatting Bacterial Resistance in Europe (COMBACTE-NET)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2019,

The emergence of Antibiotic-resistant bacteria (ARB) is a global problem, having recently been elevated to the top three threats identified by the World Health Organisation (WHO), and subject of numerous national and international government activities, including the Trans-Atlantic Task Force on Antimicrobial Resistance established by the US and EU presidencies. The estimated costs of ARB are aro ...
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 38

 TERMINÉ 

Platform foR European Preparedness Against (Re-)emerging Epidemics (PREPARE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

Far from receding, the threats posed by infections with epidemic potential grow ever greater. Although Europe has amongst the best healthcare systems in the world, and also the world’s supreme researchers in this field, we lack co-ordination and linkage between networks that is required to respond fast to new threats. This consortium of consortia will streamline our response, using primary and sec ...
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 27

 TERMINÉ 
Aggression is a basic physiological trait with important roles throughout evolution, both in defence and predation. When expressed in humans in the wrong context, aggression leads to maladjustment, social impairment and crime. Despite this, knowledge about aggression aetiology is limited and current treatment strategies are insufficient. Contingent to a subdivision into impulsive and instrumental ...
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 27

 TERMINÉ 

Post-ingestive effects on mesolimbic circuitry (POST-INGEST MESOLIMB)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2018,

Recent decades have seen a rapid rise in the prevalence of obesity across the globe. This rise can be attributed, at least in part, to overconsumption of so-called junk foods, which are highly palatable and densely caloric. These foods, in particular, drive activity in the brain's mesolimbic circuitry. The mesolimbic system - primarily comprising dopamine cells in the ventral tegmental area and nu ...
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 1

 TERMINÉ 
Long-term side-effects of radiotherapy impact on the quality-of-life (QoL) of cancer survivors. These side-effects could be reduced if predicted in advance. Previous work identified clinical and biological predictors but a major, coordinated approach is needed to validate them so they can be used clinically. The EU has ~17.8 million people living with a prior diagnosis of cancer of whom ~7 million ...
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 15

 TERMINÉ 
"We propose a new strategy based on an interdisciplinary unitary and integrated approach aimed to monitor and detect small signals of impending failures and mitigate natural hazards, by:1) quantify of critical damage thresholds triggering dynamic failure, throughout the ‘In situ’ identification of characteristic slow deformation signals and accelerating patterns before impending ‘large scale’ fail ...
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 1

 TERMINÉ 
This project centres ‘the carceral archipelago’ in the history of the making of the modern world. It analyses the relationships and circulations between and across convict transportation, penal colonies and labour, migration, coercion and confinement. It incorporates all the global powers engaged in transportation for the purpose of expansion and colonization - Europe, Russia, Latin America, China ...
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 1

 TERMINÉ 

European Medical Information Framework (EMIF)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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 64

 TERMINÉ 
Drug development in TB requires new integrated methods to transition the novel combination regimens needed to shorten first-line therapy and combat multi-drug resistance. Although new agents are emerging, the path to registration of such regimens remains uncertain while capacity for pivotal trials is limited. Selection and optimization of drug combinations for development depends on preclinical sy ...
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 23

 TERMINÉ 

Reactive Atmospheric Plasma processIng - eDucation network (RAPID)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"The goal of the Multi-Partner ITN-RAPID (Reactive Atmospheric Plasma processIng - eDucation network) is the realization of an interdisciplinary training involving the disciplines physics, chemistry and engineering. As a result, RAPID will create the platform for a truly European PhD in plasma technology. The scientific goal is the development of non-equilibrium reactive processes in atmospheric p ...
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 10

 TERMINÉ 

Control of metabolic and inflammatory pathways by nuclear receptors (NR-NET)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

NR-NET is a multidisciplinary consortium, whose activities are directed towards the understanding of the role of Nuclear Receptors (NRs) and coregulators in metaflammatory disease. Metaflammation - metabolic disorders linked to chronic inflammation – is an emerging concept explaining the pathogenesis of a wide-spectrum of diseases. Since several nuclear receptors can directly sense metabolic alter ...
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 11

 TERMINÉ 
Atherosclerosis and its most disabling sequelae, coronary artery disease (CAD) and stroke, are leading causes of death in Europe. Until now, preventive and therapeutic interventions for these diseases aim at ameliorating the effects of established cardiovascular risk factors. More recently, results of genome-wide association (GWA) studies added to our perception of mechanisms leading to atheroscle ...
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 13

 TERMINÉ 
Escalating incidents in complex environments can lead to severe cascading effects and quickly become extremely difficult for emergency services to handle. Such incidents can have enormous consequences with respect to life, property and the environment and for both infrastructure and the general public. These consequences can in many situations have both direct and indirect effects, not only in the ...
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 13

 TERMINÉ 

Insect Timing (INsecTIME)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,

INsecTIME seeks to train the next generation of ESRs in the intellectual, technological, complementary and commercial skills required for future European competitiveness in the area of biological timing, an area with considerable commercial potential. The scientific focus will be on circadian and seasonal rhythms in the model insect, Drosophila, which has proved particularly relevant for understan ...
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 10

 TERMINÉ 
This project explores Anglo-Indigenous interactions in colonial New England via historical archaeology. It draws upon archival data collected on both sides of the Atlantic Ocean along with archaeological data collected from three sites in North America. Together these data offer the opportunity to investigate the complexities of cultural continuity and change in colonial contexts, to examine the l ...
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 1

 TERMINÉ 
The 2010-2011 youth-led wave of protests in the South and East Mediterranean, could be described as the coming on the scene of a new generation united by a shared experience of marginalisation and by new ways to protest and act. Important as this phenomenon could be for the future of the SEM, it still escapes the main frames of analysis utilised by academic research. Youth studies in the SEM, whil ...
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 14

 TERMINÉ 

BBMRI - Large Prospective Cohorts (BBMRI-LPC)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,

In recent years, biomedical research has crossed international borders in large, collaborative studies showing the value of multidisciplinarity and scale advantage. This has yielded valuable insights and some led to new and better medicines and treatments for diseases. However, disease-focused studies provide less insight in the real disease onset, the relative disease burden in the population, an ...
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 36

 TERMINÉ 

Incorporating real-life clinical data into drug development (GETREAL)

Date du début: 1 oct. 2013, Date de fin: 31 déc. 2016,

When a new medicine reaches the market, it is accompanied by an extensive data package that provides information about the safety and efficacy of the medicine in a clinical trial setting. However, assessing the expected future value of the medicines when used in “real world” clinical practice requires additional information next to traditional (pre-authorisation) clinical trials. Regulatory, HTA ...
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 32

 TERMINÉ 
The eTOX consortium proposes to develop innovative methodological strategies and novel software tools to better predict the toxicological profiles of new molecular entities in early stages of the drug development pipeline. This will be achieved by coordinating the efforts of specialists from academia and SMEs in the wide scope of disciplines that are required to move towards a more reliable modell ...
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 30

 TERMINÉ 
"In stark contrast to the abundance of high quality palaeoenvironmental records obtained from the temperate regions of the northern hemisphere, terrestrial palaeoenvironmental information from southern Africa's drylands comes from discontinuous deposits with poor absolute age control and ambiguous palaeoclimatic significance. Confronted with the possibility of future environmental and social disru ...
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 2

 TERMINÉ 
"This project proposes unique research training opportunities by bringing together partners with complementary expertise in engineering, electrophysiology, molecular biology, cellular neuroscience, theoretical neuroscience, and advanced data analysis. Trainees will participate in the design and implementation of novel tools and platforms to advance current understanding of the molecular and microc ...
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 3

 TERMINÉ 
A new Aeronautical Training Network is proposed to train Early Stage Researchers and Experienced Researchers in front-line, integrated, industry relevant research in unsteady aerodynamics and noise for the next generation of environmentally friendly wide-body civil aircraft. Building upon the multi-host EST FP6 programme AeroTraNet, AeroTraNet 2 clusters the complementary expertise of 5 establishe ...
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 8

 TERMINÉ 

Cobalt and lanthanide recovery from batteries (COLABATS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

"The COLABATS project will provide new industrial processes for the recycling of the critical metals Cobalt and Lanthanides and key economic metals Nickel and Lithium, from waste batteries, significantly improving recycling efficiencies and metal purity from existing recovery routes. Primarily Li-ion and NiMH will be targeted using novel task specific ionic liquids (TSILs) to selectively extract t ...
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 10

 TERMINÉ 
The airways diseases asthma and chronic obstructive pulmonary disease affect over 400 million people world-wide and cause considerable morbidity and mortality. Airways disease costs the European Union in excess of €56 billion per annum. Current therapies are inadequate and we do not have sufficient tools to predict disease progression or response to current or future therapies. Our consortium, Air ...
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 40

 TERMINÉ 
Landmines and the cluster munitions still kill or maim civilians every day in an indiscriminate manner even long after conflicts are over. At the current rate of clearance of about 500,000 mines per year and assuming no additional mines are laid from now on, it could still take hundreds of years to find and clear all the landmines around the world.D-BOX will tackle the burning issue of anti-person ...
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 24

 TERMINÉ 

ARCHES : Astronomical Resource Cross-matching for High Energy Studies (ARCHES)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,

"ARCHES will focus on the X-ray survey catalogue data from the XMM-Newton mission. New tools will be developed for cross-correlation with extensive archival resources, producing well-characterised multi-wavelength data in the form of spectral energy distributions for large sets of objects. These enhanced resources will significantly broaden the effective exploitation of the data by the scientific ...
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 5

 TERMINÉ 

Integrated non-CO2 Greenhouse gas Observing System (INGOS)

Date du début: 1 oct. 2011, Date de fin: 31 déc. 2015,

InGOS will support and integrate the observing capacity of Europe for non-CO2 greenhouse gases (NCGHG: CH4, N2O, SF6, H2 and halocarbons). The emissions of these gases are very uncertain and it is unknown how future climate change will feedback into the land use coupled emissions of CH4 and N2O. The NCGHG atmospheric abundances will increase further in the future and the emissions of these gases a ...
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 39

 TERMINÉ 

Near-Earth Space Data Infrastructure for e-Science (ESPAS)

Date du début: 1 nov. 2011, Date de fin: 30 nov. 2015,

The ESPAS project will provide the e-Infrastructure necessary to support the access to observations, the modeling and prediction of the Near-Earth Space environment. This includes the plasma and energetic particle environments that surround our planet as well as the neutral atmosphere at altitudes above 60 km. These environments are an important target for future research in areas such as space we ...
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 22

 TERMINÉ 
ENS4Care will build a sustainable network of key stakeholders – nurses and social care workers, patients, industry, public authorities and research excellence centers – focusing on developing guidelines for the deployment of eHealth services, mainly telehealth and telecare services, anchored on proven successful, implemented and cost-effective telehealth and telecare practices in the field of prev ...
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 24

 TERMINÉ 

Space WIreless sensor networks for Planetary Exploration (SWIPE)

Date du début: 1 avr. 2013, Date de fin: 31 oct. 2015,

"SWIPE intends to bring Wireless Sensor Networks based on MANET terrestrial technology to space. In order to prepare for manned missions to other planets, it is necessary to monitor permanently the surface environment and have a clear notion of its conditions. Hundreds or thousands of small wireless sensors could be dropped from a satellite orbiting the planet onto the surface to assure a uniform ...
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 6

 TERMINÉ 
The 21st century museum mission has been re-interpreted. Heritage institutions are called to improve and find new ways to present content in order to convey knowledge and engage visitors. Arguably, digital media have an increasingly prominent role in the communication and interpretation of heritage while digital technology continuously improves. But can technical innovation alone yield new communi ...
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 1

 TERMINÉ 

Mobility between Europe and Argentina applying Logics to Systems (MEALS)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,

Computing systems are getting ever more ubiquitous, making usdependent on their proper functioning. Therefore we require that theyare correct (i.e. they conform their intended behavior), safe (i.e.itsoperation does not have catastrophic consequences), reliable,available to provide the intended service, and secure (i.e., no userwithout appropriate clearance can access or modify protected data).Guar ...
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 8

 TERMINÉ 

Homotopy algebras in homotopy theory and higher category theory (HOMALGHIGH)

Date du début: 1 sept. 2011, Date de fin: 31 août 2015,

"We will study in this project exciting new interactions and applications between two fundamental modern research areas of mathematics, homotopy theory and higher category theory. These areas of mathematics are used in applied sciences. For instance, homotopy theory is used in robotics and in computer science. Higher category theory studies the way in which complex structures arising for instance ...
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 2

 TERMINÉ 
GAP2 is about making a difference to an issue of significance to the whole of society; the wellbeing of the marine environment and the sustainability of fisheries upon which society depends for food. It builds on the relationships, processes and plans arising from GAP1 by enabling Mobilisation and Mutual Learning (MML) actions that promote stakeholder participation in the debate on and development ...
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 39

 TERMINÉ 
Heart failure is common in Europe and its prevalence is increasing as our population ages. Despite major improvements in care since the early 90s, it is still related to a poor prognosis, an impaired quality of life and high health care costs. Many new therapies have failed to improve outcome further. One obvious reason is that the response to treatment is not homogenous. Treatment may need to be ...
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 11

 TERMINÉ 
"Many results drawn from previous studies of the effect of antibiotic use on emergence, selection and spread of antimicrobial resistance (AMR) have lacked a holistic view combining all aspects into one study. The SATURN project aims to study the impact of antibiotic exposure on AMR with a multidisciplinary approach that bridges molecular, epidemiological, clinical and pharmacological research. Two ...
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 16

 TERMINÉ 
"In order for the EC to achieve ambitious renewable energy targets there is a strong need to accelerate market penetration of Renewable Energy Systems (RES) in both industrial and domestic sectors. The domestic sector is of major significance, as it will reduce reliance on large centralized energy plants. There are several domestic options including solar thermal, solar electric, heat pump and bio ...
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 14

 TERMINÉ 
This proposal is presented by a consortium of regional research clusters whose core members are already pursuing research and technology development (RTD) in programmes that map on to their local or regional transport policy priorities. Common themes of expertise within the consortium apply to the fields of Traffic, Health and Environment (THE); the objective of the project is to apply this resear ...
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 13

 TERMINÉ 
"Recently, research in astrophysics has yielded amazing new insight in the origin, evolution and structure of the Universe, and fundamental processes governing this highly dynamical system. Most of this progress was achieved thanks to the availability of extremely sensitive detectors. Common features for such detectors are extremely low noise and very small background, and the main solutions for a ...
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 9