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 EN COURS 
Imagine if tumor growth would be reduced and then kept in a minimal and safe volume in an automated manner and in a personalized way, i.e. cancer drug would be injected using a continuous therapy improving the patient’s quality of life.By control engineering approaches it is possible to create model-based strategies for health problems. Artificial pancreas is an adequate example for this, where by ...
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 2

 TERMINÉ 

Secondary prEvention of CardiovascUlaR disease in the Elderly trial (SECURE)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,

While Cardiovascular diseases (CVD) are the main cause of death worldwide, they are responsible for half of all deaths in Europe. The overall ageing of the European population and improving survival of patients with coronary heart disease has created a large population of older adults eligible for secondary prevention. Despite the established efficacy of cardiovascular medications, suboptimal adhe ...
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 13

 TERMINÉ 
Cancer is a leading cause of mortality within the aging European population. Therapeutic targeting is hampered by the complexity of the disease, which includes not only molecular changes within the tumor cell itself, but also within its microenvironment. Tumor angiogenesis, tumor-stroma interactions, interactions with immune cells, with the extracellular matrix and cancer stem cell niches allow fo ...
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 10

 TERMINÉ 

Added Value for Oral Care (ADVOCATE)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

ADVOCATE brings together top principal investigators from prestigious universities, the public sector, and the private sector to address the most common diseases affecting humanity, as measured by the recent Global Burden of Disease Study. ADVOCATE strives to optimise delivery of oral health and wellbeing to the population in EU Member States. This requires a change in oral health care delivery to ...
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 13

 TERMINÉ 
Coronary artery disease (CAD) is the leading cause of death in high-income countries. Invasive coronary angiography (ICA) is the reference standard for the diagnosis of CAD and allows immediate therapy. However, only 40% of patients undergoing ICA actually have obstructive CAD and ICA has relatively rare but considerable risks. Coronary computed tomography (CT) is the most accurate diagnostic test ...
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 38

 TERMINÉ 

Dobutamine for NEOnatal CIRCulatory failure defined by novel biomarkers (NEO-CIRC)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2018,

Dobutamine and adrenaline are widely used as second line therapy for systemic hypotension in infants. Dopamine is currently the most widely used first line drug. In neonates, sustained hypotension may, and impaired organ perfusion will, cause brain injury and poor neurodevelopmental outcomes. All three catecholamines are currently used off-label and have different modes of action which may result ...
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 20

 TERMINÉ 
"Traumatic brain injury (TBI) is among the leading causes of death and disability and the main cause of death among the under-45s. Most patients with moderate to severe TBI are admitted to intensive care units (ICUs)The “PROSAFE” ICU network was recently established in 6 European countries through EU funding (PHEA 2007331), and has continued to collect high-quality data beyond the grant duration. ...
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 11

 TERMINÉ 
This is a project for higher education student and staff mobility between Programme Countries and Partner Countries. Please consult the website of the organisation to obtain additional details.
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 1

 TERMINÉ 
CosmoPHOS-nano is a multidisciplinary, translational and business-oriented project, aiming to accomplish the following objectives:1) develop the CosmoPHOS system, which is a novel theranostic (diagnostic & therapeutic) nanotechnology-enabled portable combination system enabling endovascular in vivo near-infrared fluorescence molecular imaging, endovascular near-infrared targeted photodynamic thera ...
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 20

 TERMINÉ 
NanoAthero aims to have demonstration of initial clinical feasibility of nanosystems for targeted imaging and treatment of advanced atherosclerotic disease in humans. The nanosystems are assemblies of following components: nanocarrier, targeting, imaging agent/drug. They have proven safety records, and strong preliminary in vitro and in vivo proofs of efficacy are available. Partners have patented ...
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 17

 TERMINÉ 
In European Union approximately 5 million people suffer from psychotic disorders. Between 30-50% can be considered resistant to treatment, and 10-20% ultra-resistant. These patients present persistent positive symptomatology, require extensive periods of hospital care, and have a greater risk of excess mortality and multi-morbidity. In addition, a high proportion of the total cost for treating sch ...
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 15

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2016, Date de fin: 30 sept. 2017,

This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
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 1

 TERMINÉ 
An estimated 500.000 sudden cardiac deaths (SCD) occur each year in the European Union. Patients at risk for SCD may benefit from prophylactic treatment with an implantable cardioverter-defibrillator (ICD). ICD implantations have dramatically increased in recent years leading to multi-billion Euros of costs with significant regional disparities across Europe. Information on risks, benefits and cos ...
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 27

 TERMINÉ 
This is a project for higher education student and staff mobility between Programme Countries and Partner Countries. Please consult the website of the organisation to obtain additional details.
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 1

 TERMINÉ 

Professional profile of the surgical trainer: Train-the-Trainer curricula

Date du début: 1 sept. 2014, Date de fin: 30 juin 2017,

... Train-the-Trainer curricula (SurgTTT) Strategic partnership of the University of Applied Sciences (HTWK) Leipzig, Germany; the Jesús Usón Minimally Invasive Surgery Centre (CCMIJU) Cáceres, Spain; Semmelweis University Budapest, Hungary and the MEDIS Foundation Campina, Romania. Background of the project is the need to improve specialty training in surgical specialties and a lacking standardizatio ...
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 4

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2015, Date de fin: 31 mai 2017,

This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
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 1

 TERMINÉ 

Intelligent Catheters in Advanced Systems for Interventions (INCITE)

Date du début: 1 mars 2014, Date de fin: 1 mars 2017,

INCITE aims to develop intelligent catheter technologies and systems that will accelerate the paradigm shift from costly, burdensome surgical treatments to cost-effective and patient-friendly minimally invasive interventions. It will also enable the creation of new advanced treatments for currently complex surgical procedures. This will allow for more individuals to be treated thereby contributing ...
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 24

 TERMINÉ 

Imaging of Neuroinflammation in Neurodegenerative Diseases (INMiND)

Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,

The goal of this proposal (INMiND) is to carry out collaborative research on molecular mechanisms that link neuroinflammation with neurodegeneration in order to identify novel biological targets for activated microglia, which may serve for both diagnostic and therapeutic purposes, and to translate this knowledge into the clinic. The general objectives of INMiND are:(i) to identify novel mechanisms ...
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 32

 TERMINÉ 
Over the last 40 years, treatment for childhood and adolescent cancer has improved greatly; 5- year survival after childhood cancer is now 80% in developed countries. Approximately 1 individual in 750 of young adults is now a childhood cancer survivor. Epidemiologic data on the number of European childhood cancer long-term survivors are not available, but estimates suggest a number between 300,000 ...
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 18

 TERMINÉ 

Expressive Agents for Symbiotic Education and Learning (EASEL)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,

EASEL will explore and develop a theoretical understanding of human-robot symbiotic interaction (HRSI) where symbiosis is defined as the capacity of the robot and the person to mutually influence each other, and alter each other's behaviour over different time-scales (for instance, within encounters and across encounters). Symbiosis requires that the robot can read, and be responsive to, the behav ...
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 5

 TERMINÉ 
There is a striking lack in structured and standardized training infrastructure for neurodevelopmental disorders across Europe. Such training will be fundamental to promoting standards of care across Europe and will ultimately lead to strategies for the promotion of childhood mental health in Europe. The focus of this Initial Training Network (ITN) is Gilles de la Tourette Syndrome (TS), an inheri ...
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 12

 TERMINÉ 
Cancer is the second largest cause of death and morbidity in Europe, with more than 3 million new cases diagnosed each year. The most effective treatment strategy for most forms of cancer is early detection followed by surgery. However, cancers frequently recur following surgery. For example, nearly 1 in 4 breast cancer patients will see their tumour recur after surgery. The consequences of cancer ...
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 8

 TERMINÉ 

Assessing the effect of early social environment on epigenetic modification (SEEM)

Date du début: 1 sept. 2011, Date de fin: 30 août 2016,

"Genetic and environmental factors shape resiliency and vulnerability to psychiatric disorders, as in other complex inheritance diseases. Recent studies show that environmental factors can exert their effects through epigenetic modifications, such as DNA methylation, affecting expression level of crucial genes. Pre- and postnatal environment (e.g. maternal diet, stress, early care) in critical per ...
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 2

 TERMINÉ 
The airways diseases asthma and chronic obstructive pulmonary disease affect over 400 million people world-wide and cause considerable morbidity and mortality. Airways disease costs the European Union in excess of €56 billion per annum. Current therapies are inadequate and we do not have sufficient tools to predict disease progression or response to current or future therapies. Our consortium, Air ...
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 40

 TERMINÉ 

Creating the Hungarian Centre of Excellence for Molecular Medicine (HU-MOLMEDEX)

Date du début: 1 juin 2015, Date de fin: 31 mai 2016,

Existing European disparity in research and innovation performance is a barrier to competitiveness and growth. To overcome this disparity, the leading institute in molecular life sciences and three research universities of Hungary have joined forces forming a new Centre of Excellence for Molecular Medicine (HCEMM). These institutions have the necessary basic research and clinical portfolio to init ...
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 7

 TERMINÉ 

DYNAMIC INTERACTIVE NANOSYSTEMS (DYNANO)

Date du début: 1 nov. 2011, Date de fin: 29 févr. 2016,

"The key and direct objective of DYNANO is to provide training with a deep knowledge and expertise on Dynamic Interactive Nanosystems for biomedical and biotechnological applications on the basis of the existing scientific and technological areas: dynamic chemistry / glycosciences / biology / nanosciences. DYNANO will expose researchers in training to the process of design, generation, optimizatio ...
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 13

 TERMINÉ 
"The aim of TINN2 is to evaluate azithromycin, included in the EMEA priority list of the therapeutic areas that need specific drug evaluation in preterm and term neonates. Azithromycin is a macrolid antibiotic with anti-inflammatory properties active against Ureaplasma. It might be effective in reducing the severity of bronhopulmonary disease in which Ureaplasma infection and inflammation play a r ...
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 17

 TERMINÉ 
The project aims to develop novel inhibitors of chronic autoimmune and inflammatory diseases by targeting members of the Src tyrosine kinase family. Src-family kinases have recently emerged as major therapeutic targets in malignant diseases but their suitability as potential targets of inflammatory diseases has not yet recieved widespread acceptance. On the other hand, members of the applicant con ...
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 11

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2014, Date de fin: 30 sept. 2015,

Joining the Erasmus+ programme was an important strategic decision of Semmelweis University. We strive to build long term relationships with leading healthcare and scientific institutions in and outside of Europe. Our university’s international relations are in line with our commitment to education, research and health care. Apart from partnerships within the framework of Erasmus+, we have other r ...
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 1

 TERMINÉ 

Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2015,

RationaleThe inability of pre-clinical studies to predict clinical efficacy is a major bottleneck in drug development. In severe asthma this bottleneck results from: a lack of useful and validated biomarkers, underperforming pre-clinical models, inadequate and incomplete sub-phenotyping, and insufficient disease understanding.HypothesisThe use of biomarker profiles comprised of various types of hi ...
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 42

 TERMINÉ 

A Roadmap for Mental Health Research in Europe (ROAMER)

Date du début: 1 oct. 2011, Date de fin: 31 mars 2015,

"On the regional level, Europe has one of the highest levels of resources for mental health care. Despite this, the high burden and impact of mental disorders in Europe is expected to rise. “ROAdmap for Mental health Research” (ROAMER) is designed to develop a comprehensive, consensus-based roadmap to promote and integrate mental health and well-beingresearch in Europe. Research advances and innov ...
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 15

 TERMINÉ 
The endocannabinoid system is composed of endocannabinoids, such as anandamide and 2-arachidonoylglycerol (2-AG), their metabolizing enzymes and cannabinoid receptors. To date, two cannabinoid receptors have been identified by molecular cloning, the CB1 and CB2 receptors. The endocannabinoid system has been implicated in a number of physiological functions, and pharmacological manipulation of this ...
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 2

 TERMINÉ 

Systems biology towards novel chronic kidney disease diagnosis and treatment (SysKID)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2014,

Chronic kidney disease (CKD) affects up to 10% of the population. Besides eventual progression towards end stage renal disease CKD impacts the patient’s quality of life by causing serious comorbidities including cardiovascular complications and bone metabolism disorders. On the everyday clinical level early stage diagnosis and tailored treatment of CKD are still inadequate. In addition, CKD seems ...
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 30

 TERMINÉ 
"The strategic development of accurate biomarkers to predict response to therapy in cancer medicine will enhance clinical outcome and reduce the health economic impact of drug resistant disease. The PREDICT consortium will identify and validate predictive biomarkers for two drugs which have direct anti-tumour cell and anti-angiogenic activity and for which no established predictive biomarkers of t ...
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 16

 TERMINÉ 

EuroHOPE – European Health Care Outcomes, Performance and Efficiency (EuroHOPE)

Date du début: 1 janv. 2010, Date de fin: 30 avr. 2014,

By using available databases as well as by collecting additional data on health-related quality of life measures (enabling Quality Adjusted Life Years as an outcome measure) and patient satisfaction (including expectations) the EuroHOPE project will evaluate, through a microeconomic disease-based approach, the performance of European health care systems in terms of outcomes, quality, use of resour ...
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 12

 TERMINÉ 

Pharmaceutical Medicine Training Programme (PHARMATRAIN)

Date du début: 1 mai 2009, Date de fin: 30 avr. 2014,

"The proposed Pharmaceutical Medicine Training Programme provides a comprehensive solution for the complex needs of integrated drug development for all professionals involved, incl. physicians, pharmaceutical scientists,biologists, biometricians, health economists, and safety and regulatory scientists from universities, regulatory agencies, large, middle-sized and small pharmaceutical enterprises, ...
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 52

 TERMINÉ 

Molecular dissection of inflammatory pathways (MOLINFLAM)

Date du début: 1 oct. 2008, Date de fin: 31 mars 2014,

Inflammatory diseases are highly prevalent, often chronic diseases that cause diminished quality of life and are connected with major causes of death in Western societies. Despite their societal impact, their pathomechanism is incompletely understood, hindering development of novel therapeutic strategies. In particular, little is known about the intracellular signal transduction processes involved ...
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 2

 TERMINÉ 
In Hungary the partnership of 18 institutions (one organisation managing and coordinating EU and educational and training grants, 14 top universities, two research institutes, one Observatory and numerous additional HEIs, science museums, research institutes and research groups joining the consortium as indirect partners) will organise RN 2013 with the aim of enhancing the public recognition of re ...
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 19

 TERMINÉ 

EUropean Cross Border Care Collaborations Short Title: CrossEurope (EUCBCC)

Date du début: 1 mai 2010, Date de fin: 31 oct. 2013,

"EUCBCC aims to facilitate a process whereby Europe's citizens can make informed choices about whether to seek health care in another Member State and, if they so choose, to ensure that the admin and clinical processes are straightforward and ensure continuity of care. It takes as its starting point the recent draft Directive on Patients' Rights, augmented by the existing body of research on cross ...
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 15

 TERMINÉ 

European Project on Mendelian Forms of Parkinson’s Disease (MEFOPA)

Date du début: 1 avr. 2010, Date de fin: 30 sept. 2013,

"The Collaborative Project on Mendelian Forms of Parkinson’s Disease (MEFOPA) will bring together the major groups in Europe with a track-record in basic and clinical research on rare Mendelian forms of Parkinson’s disease (PD) in order to identify and validate relevant disease-related molecular pathways, drug-targets and biomarkers for disease susceptibility and progression.. Over the last years ...
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 27