29 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
The Elementary Theory of Partially Commutative Groups (PCG)
Date du début: 1 sept. 2014, Date de fin: 31 août 2019,
"The solution of Tarski's problems on the first-order theory of freegroups has uncovered deep connections between Model Theory, Geometryand Group Theory and served as a nexus and motivation for manyclassical results in Geometric Group Theory and Theoretical ComputerScience.Just as the Tarski problems connected the theory of free groups withthe geometry of trees, our goal is to point at a new dire ...
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1
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TERMINÉ
Automated financial modelling (AUTOFIM)
Date du début: 1 sept. 2007, Date de fin: 31 août 2009,
...as proposed and developed in a series of papers which overcomes many of the computational challenges earlier associated with automated financial volatility modelling. Moreover, softwares (for example PcG ets) in which the methodology can be implemented in an automated manner is already available, so that only minor modifications and additions to the methodology are necessary before it can be used ...
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1
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TERMINÉ
Topoisomerase Function in genome and epigenome regulation during Neuronal Differentiation (toponeuronal)
Date du début: 1 mars 2009, Date de fin: 28 févr. 2011,
...ecific activation. This function could be achieved by regulating higher order chromatin organization of target genomic regions and/or direct interaction with known partners such as condesin and PcG proteins (Lupo R. et al., 2001) and other epigenetic modifiers such as chromatin remodeling complexes. We propose to define the contribution of TopIIβ activity towards epigenetic regulation of neuronal ...
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1
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TERMINÉ
Polycomb in development, genome regulation and cancer (FLYINGPOLYCOMB)
Date du début: 1 sept. 2009, Date de fin: 31 août 2015,
Polycomb group (PcG) and trithorax group (trxG) genes were discovered in Drosophila melanogaster as repressors and activators of Hox genes, a set of transcription factors that specify the antero-posterior axis of the body plan. PcG and trxG proteins form multimeric complexes that are required to maintain their expression state after the initial transcriptional regulators disappear from the embryo. ...
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1
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TERMINÉ
The Polycomb Repression Complex 2 (PRC2): Mechanisms of recruitment and role in tumorigenesis (PReMORRIT)
Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,
...rmation"". Different parameters defined the chromatin structure among which DNA methylation, histone variant incorporation and histone post-translational modifications (PTMs).Polycomb Group proteins (PcG) were identified in Drosophila by mutations that result in segmental transformation and are known to be required for proper development in mammals. It was shown that PcG proteins maintain the repr ...
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1
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TERMINÉ
Chromatin Dynamics of Stem Cells and Lineage Commitment in Plant Development (ChroMorpho)
Date du début: 1 juin 2011, Date de fin: 31 mai 2013,
...ineage commitment are controlled by unique transcription factor networks and conserved chromatin factors including nucleosome remodelers, histone variants and histone modifiers of the Polycomb group (PcG, epigenetic repressors) as well as Trithorax group (TrxG, epigenetic activators). Moreover, in stem cells the histone variant H2A.Z collaborates with PcG factors and is pivotal for timely activati ...
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2
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TERMINÉ
Regulation of Polycomb Complex (PRC2) during development and in diseases (REPODDID)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2017,
Polycomb Group (PcG) proteins are pivotal for the specification and maintenance of cell identity by preventing inappropriate gene activation. They function mostly through the regulation of chromatin structure and, in particular, the post-translational modification of histones. Although the enzymatic activities of the main PcG complexes has been described, lots remain to be discovered in terms of h ...
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1
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TERMINÉ
Polycomb/Trithorax: Functional EpiGenomics Integrators for Metabolic Disease (MetabolicPolycombics)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2016,
... among the most enriched pathways (Pospisilik, Cell 2010). Systematic interrogation of the 500 candidate obesity genes by tissue-specific knockdown has now identified the Polycomb-Trithorax system (PcG-Trx) as the most enriched obesity-altering pathway. Here, we propose to translate these findings to the mammalian context through completion of three aims: i. generation and characterization of 8 Pc ...
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1
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TERMINÉ
Mechanisms of polyploidy-mediated postzygotic reproductive isolation (Triploid Block)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,
...nt work from our laboratory uncovered a genetic pathway leading to unreduced gamete formation at high frequency and revealed that the triploid block is mainly caused by malfunction of Polycomb group (PcG) proteins. PcG proteins are evolutionary conserved proteins, which assemble into multimeric complexes with chromatin-modifying enzymatic activity, implicating epigenetic regulatory mechanisms as a ...
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1
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TERMINÉ
Polycomb and Trithorax Group Proteins: Master Regulators of Adipose Tissue Function? (ATACC)
Date du début: 1 juin 2012, Date de fin: 31 mai 2014,
...convergence in metabolic phenotype of these two disparate disorders highlights how a precisely controlled, metabolically active adipose tissue is essential for proper health.Polycomb/Trithorax group (PcG/Trx) proteins were first identified in D. melanogaster as modulators of developmental patterning genes and are now recognized as fundamental executors of a chromatin-based silencing system that, c ...
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1
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TERMINÉ
A Direct Role for Nucleosome Turnover in Polycomb Response Element Function (REPLACOMB)
Date du début: 1 sept. 2012, Date de fin: 31 août 2015,
"Polycomb group (PcG) and Trithorax group (TrxG) proteins are essential for maintaining different cell identities through chromatin-based regulation of gene expression during development. A crucial aspect of this system is the competition of PcG and TrxG proteins for cis-regulatory DNA elements called Polycomb Response Elements (PREs). However, the mechanisms underlying this competition remain lar ...
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1
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TERMINÉ
Polycomb repressor interactions in relation to the mammalian epigenome (PRIME)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
"In mammals Polycomb group (PcG) repressors play a central role in maintaining cell type specific gene expression patterns in stem cells and through differentiation and development. Accordingly, deficiencies in the Polycomb system are important in disease, notably in several types of cancer. Although it is established that the effector function of PcG proteins is in large part attributable to in ...
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1
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TERMINÉ
Landscape of epigenetic control in early and late germ line development (epiGERMetics)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2018,
...tebrates, using zebrafish as a genetic model. My hypothesis is that epigenetic control of gene expression is regulated in both the nucleus and cytoplasm of germ cells. In the nucleus, Polycomb Group (PcG) proteins regulate transcription by establishing repressive chromatin modifications. In the germ cytoplasm, translational regulation by Argonaute proteins, involved in RNA silencing pathways, is p ...
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1
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TERMINÉ
Avrupa Vizyonu ile Ortaöğretimde PDR Yaklaşımları
Date du début: 31 déc. 2015, Date de fin: 30 déc. 2016,
Psychological Counseling and Guidance (PCG) concepts refer to activities that became crucial parts of the modern education. Especially the guidance term, even if mentioned within the curriculum during 1938, gain vast popularity as of the 1950's. Particularly after the 1970's phsycological counseling and guidance services take place in our education programmes held by "experts" as a specific "assis ...
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1
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TERMINÉ
Mobile Training for Home and Health Caregivers For People with Disabilities and Older People
Date du début: 1 janv. 2014,
European people with disabilities (especially those with mobility impairments) depend heavily on personal care givers (PCGs). While this assistance is crucial in ensuring a daily quality of life (assisting with basic tasks such as getting dressed, eating, taking a bath/shower), it is still quantitatively and qualitatively a huge problem. Few PCGs get a proper training, if any, while such formal tr ...
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6
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TERMINÉ
Development and improvement of cycling route network in Central Baltic area (CentralBalticCycling)
Date du début: 31 déc. 2011, Date de fin: 29 juin 2013,
...tions for locals,and improved leisure environment for tourists.WP4 is aimed at direct communication with foreign tourists and tourist offices to promote CB as a cycling destination. Results:3 PSG& 5 PCG meetings,5 thematic workshops,23 training workshops,2 cycling conference,cycling maps and brochures,participation in 6 tourism fairs, route signs, information stands, bicycle parking stands, techn ...
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8
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TERMINÉ
Developing and testing innovative blended work based learning in VET
Date du début: 1 sept. 2015, Date de fin: 31 août 2018,
The aim of the project is to embed and mainstream the innovation and adaptation of work based delivery models, piloted as part of the Leonardo MOVE IT (2012-1-GB2-LEO05-08040) project, whilst continuing to advance and understand more about pedagogical approaches in the workplace, opportunities through collaborative learning and advances in the application of new learning technologies. In doing so ...
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4
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TERMINÉ
A.C.T.I.O.N! – Acquisition of Competences to Improve Opportunities Now!
Date du début: 1 juin 2016, Date de fin: 30 sept. 2017,
The project “A.C.T.I.O.N! – Acquisition of Competences to Improve Opportunities Now!” is going to take place in the small rural village of Brtonigla, in Istria region (Croatia) where the head office of LDA is located, Brtonigla. Because of the particular ethnic structure of Verteneglio, the NGO Local Democracy Agency (LDA) was founded in 1996 to support multiculturality and cohabitation of all di ...
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5
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TERMINÉ
Youth Community-based Oral Health Learning Model
Date du début: 2 févr. 2015, Date de fin: 1 févr. 2017,
Poor oral health has a detrimental effect on youth’s quality of life, their performance at school and their success in later life. Youth who suffer from poor oral health are 12 times more likely to have restricted-activity days than those who do not.
European Ministers have asserted that the needs of EU citizens must be the centre of attention in the development of high quality health related inf ...
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7
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TERMINÉ
Reduced energy use in the NSR horticultural greenhouse industry (GreenGrowing)
Date du début: 30 sept. 2011, Date de fin: 29 juin 2015,
GreenGrowing will strengthen the innovation capacity and competitiveness in the NSR horticultural greenhouse industry and lead to at least a 10% reduction of CO2 emissions. The project will combine a better climate control in the greenhouses, an improved use of novel greenhouse techniques and the use of climate tolerant plant types with ICT tools. Supported by intensive information strategies at t ...
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9
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TERMINÉ
ftuin Kaderrichtlijn Water (Proeftuin Kaderrichtlijn Water)
Date du début: 31 oct. 2010, Date de fin: 30 oct. 2013,
Eind 2015 zullen alle lidstaten van de Europese Unie moeten zorgen dat het oppervlakte- en grondwater een goede kwaliteit heeft. Ondanks alle inspanningen blijkt dat de waterkwaliteitsnormen nog steeds worden overschreden. In een drietal polders zal via een integrale aanpak, die er op gericht is om meer dan de wettelijk voorgeschreven maatregelen uit te voeren, nagegaan worden of een dergelijke aa ...
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6
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TERMINÉ
Groene Grondstoffen
Date du début: 31 déc. 2009, Date de fin: 30 déc. 2012,
Het project stimuleert en ondersteunt de kennisontwikkeling en innovatie rond nieuwe toepassingen van plantaardige productie. Verder wil men de nieuwe economische ketenvorming/groepen en het koppelen van bedrijven tussen, of over sectoren heen, rond innovatieve toepassingen van landbouwgewassen stimuleren.Concreet beoogt het project 8 nieuwe toepassingsmogelijkheden van groene grondstoffen te ontw ...
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6
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TERMINÉ
Aqua-VLAN
Date du début: 31 août 2009, Date de fin: 30 août 2012,
Het project beoogt het bouwen van de fundamenten van een economisch, sociaal en ecologisch duurzame aquacultuursector binnen de grensregio zodat de huidige beperkte aquacultuursector verder kan uitgroeien.Hierbij wordt gewerkt volgens het concept “Fork to Farm” zodat een breed draagvlak voor de regionale aquacultuursector kan ontstaan. Het verbeteren van de kennisoverdracht binnen de driehoek: ken ...
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8
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TERMINÉ
Using Data for Improving School and Student Performance
Date du début: 1 nov. 2010,
The aim of this project is to develop the skills of school leaders to establish learning communities where data are used to improve educational outcomes. Specifically, the project will help school leaders develop a vision and strategy for using data to improve educational outcomes; increase the understanding of how to maximize the use of available data among school leaders; build key data, use ski ...
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5
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TERMINÉ
In the sector of the landscaped arboriculture, every country has or not certificates or national diplomas. But there are also two European certificates delivered by the European Arboriculture Council ( EAC):- European Tree Worker (ETW): for the professionals realizing operations of plantation, pruning and care in ornamental trees. - European Tree Technician (ETT): for the clerk of works in green ...
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6
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TERMINÉ
Cradle-to-Cradle (C2C) is a new, rewarding and very innovative concept used in more and more companies in Western Europe. C2C fits the EU policy of achieving a Carbon Low Society and for New Skills for New Jobs.One of the founders of the C2C concept, the German chemist Michael Braungart, is very active in his country. C2C has to become part of the corporate training system and the educational syst ...
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15
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TERMINÉ
With the exeption of The Netherlands, the Big Picture Learning (BPL) concept is relatively new for the project partners in Italy, Bulgaria, Romania and Turkey. They believe that the creation of BPL networks in their countries will greatly benefit the educational institutions, business and career guidance institutes, who can work together to implement the idea of the BPL programme. There is great n ...
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1
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TERMINÉ
This project adapted an innovative work based delivery model, developed interactive learning packages and a VLE with integrated social networking.The interactive learning packages were tested with learners by the project partners in the UK, Holland, Finland and Romania. Expertise in e-learning technology solutions and development of the VLE was provided by the Spanish project partner. Trainers wer ...
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5
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TERMINÉ
There is a strong need in Europe to broaden career education to life learning. This project establishes a link between career education for students and career management for older teachers. This can be accomplished by training in L4L (Learning for Living) an innovative method developed in the UK. The project aims to develop a model supporting career education and career management. In the project ...
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