35 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
A Szlovák és az Aggteleki Karszt mint idegengorgalmi desztináció népszerusítése / Propagácia Slovenslého a Aggtelekského krasu ako turistickej destinácie (Kras marketing / Kras marketing)
Date du début: 30 sept. 2009, Date de fin: 29 sept. 2010,
Both of the areas of the Slovak Karst National Park and the Aggtelek national park suffer from high rate of unemployment (more than 20%). The existence of the national parks prevent from building heavy industry. The are is suitable for rural tourism. The tourism offer is rich, offer a number of show caves listed on the UNESCO World Heritage Sites List. There are a number of touring routes like T ...
Voir le projet
1
Participant partenaire
TERMINÉ
750. let od založení obce Velká Kraš
Date du début: 1 mai 2006, Date de fin: 19 nov. 2006,
V rámci Smlouvy o partnerské spolupráci obcí Velká Kraš na straně ČR a Skoroszyce na polské straně jsou ve dnech od 1. 9. - 3. 9. 2006 organizovány oslavy 750. let od založení obce Velká Kraš, na které vystoupí trubači, své umění předvede orchestr mladých, je plánována ukázka šermířských dovedností, módní přehlídka, vystoupení pěveckých souborů jak z ČR, tak i Polska, roztančí nás taneční soubor ...
Voir le projet
2
Participants partenaires
TERMINÉ
Sustainable management of natural resources and regional cohesion (CARSO - KRAS)
Date du début: 31 déc. 2009, Date de fin: 29 avr. 2013,
The project is carried out on the Karst territory with the aim to promote the sustainable territory integration of the homogeneous Karst area as one of the most important area on the border between Italy and Slovenia. Expected Results: ...
Voir le projet
17
Participants partenaires
TERMINÉ
II. Slavnostní setkání občanů partnerských obcí Vidnava - Velká Kraš - Skoroszyce (Polsko)
Date du début: 31 janv. 2006, Date de fin: 31 août 2006,
V rámci smluvy o partnerské spolupráci obcí Vidnava - Velká Kraš na straně ČR a Skoroszyce na polské straně je organizováno dne 10.-11.6.2006 II. Slavnostní setkání občanů partneských obcí , ve kterém budou probíhat soutěže českých a polských hasičských družstev, turnaj v kopané TJ Vidnava a gminy Skoroszyce, turnaj ve volejbalu žen TJ Vidnava a gymnázia Skoroszyce. Koncert učitelů a žáků ZUŠ V ...
Voir le projet
2
Participants partenaires
TERMINÉ
Following the footsteps of history and beauties of nature with joy (S chuťou po stopách histórie a krás prírody .....)
Date du début: 30 juin 2010, Date de fin: 29 juin 2013,
The main target of project s to create culinary-tourism educating portal supporting the improvement of communication with visitors via portal and development of tourism in border region Achievements: The main objective was to support the development of tourism in border ...
Voir le projet
2
Participants partenaires
TERMINÉ
The role of miRNAs in KRAS-driven Non-Small Cell Lung Cancer (KRASmiR)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,
Lung cancer is the leading cause of death by cancer in Europe. Non-small cell lung cancer (NSCLC) represents about 80% of total lung cancers. KRAS is the most commonly mutated oncogene in NSCLC, found in over 20% of patients. Since KRAS mutations are directly responsible for NSCLC, KRAS represents a relevant target to prevent NSCLC development. Yet, efforts to develop therapeutic inhibitors have f ...
Voir le projet
1
Participant partenaire
TERMINÉ
KRas mutation interactions with host immunity in malignant pleural effusion (KRASHIMPE)
Date du début: 1 avr. 2011, Date de fin: 31 mars 2016,
...enocarcinomas. Although tumors involving the pleura vary in their ability to produce MPE, pathways critical for MPE formation are poorly defined. We have found that mouse tumors harboring mutant (”)KRas produce MPE in mice while tumors without ”KRas do not. LLC and MC38 lung and colon adenocarcinomas, potent inducers of MPE in syngeneic mice, harbor ”KRas that drives constitutive Ras and alternati ...
Voir le projet
1
Participant partenaire
TERMINÉ
Rýmařovsko v Opolském vojvodství
Date du début: 30 juin 2009, Date de fin: 30 janv. 2010,
Město Rýmařov již několik let rozvíjí spolupráci s gminou Ozimek v Opolském vojvodství (Opolské vojvodství má 1,5 mil. obyvatel). Přesto v naší oblasti stále nedochází k rozšíření turistického ruchu polskými občany a také malé množství obyvatel mikroregionu Rýmařovsko navštěvuje polskou republika z jiných než nákupních důvodů. Proto je hlavním záměrem projektu propagace mikroregionu Rýmařovska, je ...
Voir le projet
2
Participants partenaires
TERMINÉ
Visits trough monitor - improvement of awareness and communication between regions in slovak - czech border (Navštívme sa cez monitor)
Date du début: 30 juin 2010, Date de fin: 29 juin 2012,
... Achievements: The project was created information center for entrepreneurs, it has been upgraded www.stránky city Krasno Kysucou. In busy parts of the city it was installed five kiosks that allow citizens full access to the Internet on any given hour of the day. In the links page of the city Frenštát pod Radhoštěm ...
Voir le projet
2
Participants partenaires
TERMINÉ
Characterization and Diagnosis of Novel Molecular Tumor Markers for Personal Treatment (MOLTUMOR)
Date du début: 30 nov. 2011, Date de fin: 29 nov. 2013,
...TF promoter methylation status of 72 colon cancer samples. SZTE used bisulfite treatment of DNA to determine the pattern of methylation. BRC continued to test FFPE samples for K-Ras mutation with our KRAS Diagnostic Kit using HCT116 (K-RAS mutant) as positive control. For the detection of mutation V600E of B-RAF gene BRC developed another method besides theallele-specific PCR reaction: the HRM (H ...
Voir le projet
3
Participants partenaires
TERMINÉ
Kultura a sport bez hranic.
Date du début: 14 sept. 2006, Date de fin: 13 sept. 2007,
Akce navrhované v tomto projektu se týkají jedné z hlavních priorit Euroregionu Silesia v rámci Fondu mikroprojektů, a to rozvoje společnosti v přeshraniční oblasti se zaměřením hlavně na mládež, výchovu mladého člověka na principech partnerství a přátelstvi při aktivním sportování a odpočinku. Adresátem projektu jsou děti a mládež z české obce Píšť, které jsou ochotny navázat kontakty s mládeží s ...
Voir le projet
2
Participants partenaires
TERMINÉ
Protection and management of coastal habitats in Latvia (LV coastal habitats)
Date du début: 1 avr. 2005, Date de fin: 30 juin 2006,
Background
The Latvian coastline formed a border of the Soviet Union for several decades. Access was strictly controlled and the coast was out of bounds. As a result, its impressive array of habitat types â grey, white and wooded dunes, coastal lagoons, boreal Baltic coastal meadows, and calcareous fens â are still in good condition (23 habitat types ...
Voir le projet
3
Participants partenaires
TERMINÉ
... agreements made on youth exchanges, support for recreationalactivities and organizing workshops, an important outcome of this project is thepromotion of touristically attractive regions of Slovensky kras and Aggtelek. Achievements: Please refer to the 'Description' fie ...
Voir le projet
1
Participant partenaire
TERMINÉ
Ochrana přírody bez hranic (CZ.04.4.83/3.2.03.1/0181)
Date du début: 30 sept. 2005, Date de fin: 30 août 2006,
Základním cílem projektu je rozvoj tvůrčího přístupu dětí ve věku 10 - 18 let k tématice ochrany přírody, vzájemné spolupráce a rozvoje vzájemných vztahů bez ohledu na přítomnost hranice - tedy v přeshraničním, česko-rakouském kontextu. V rámci projektu bude realizováno společné vzdělávání cílové skupiny dětí a rozvoj jejich dovedností v oblasti práce s fotografickým přístrojem, fotografováním pří ...
Voir le projet
2
Participants partenaires
TERMINÉ
artnerská olympiáda regionů 2007 (CZ.04.4.83/3.2.01.1/0409)
Date du début: 28 févr. 2007, Date de fin: 29 juin 2007,
V rámci projektu se uspořádá IV.sportovní partnerská olympiáda regionů Hrušovansko, Mikulovsko, Moravský kras a Land um Laa. Soutěžit se bude v 6 disciplínách: fotbal, tenis, volejbal, bowling, terénní běh, střelba. Olympiáda je určena nejen pro sportovní spolky, ale i pro širokou veřejnost. Olympiáda bude probíhat dva dny (víkend), přičemž v sobotu proběhne vojelbal, tenis, bowling, terénní běh, ...
Voir le projet
4
Participants partenaires
TERMINÉ
Mezinárodní dětský letní tábor (CZ.04.4.83/3.2.01.1/0057)
Date du début: 17 juil. 2005, Date de fin: 22 juil. 2005,
Obsahem projektu je příprava o organizace letního prázdninového tábora pro cca 50 dětí ve věku 10-15 let z Dobšic, Jaroslavic a rakouských partnerských obcí Seefeld-Kadolz a Himberk. Tábor se uskuteční ve sportovním areálu v Dobšicích. V rámci programu bude organizována prohlídka pamětihodností a přírodních krás města Znojmo a znojemského regionu, krás Národního parku Podyjí a dvoudenní návš ...
Voir le projet
2
Participants partenaires
TERMINÉ
Dvoudílná propagační brožura - dotisk (CZ.04.4.82/4.3.01.1/0149)
Date du début: 15 nov. 2005, Date de fin: 29 juin 2006,
Záměrem projektu je dotisk dvoudílné informační brožury. Brožura byla již jednou vydána v nákladu 10 800 ks v české, německé a anglické verzi. O brožuru byl velký zájem, díky přehlednému vyobrazení zajímavostí a krás regionu v barevné části brožury, doplněnému stručným přehledem v jednobarevné brožuře. Materiál si získal velkou oblibu v České republice i u našich zahraničních kolegů. Nyní se jedn ...
Voir le projet
2
Participants partenaires
TERMINÉ
The main objective of the project is to protect the lives and property of people living in the affected area with the help of installation of flood warning systems in villages Beautiful Ves, Slatinka nad Bebravou, darts, which provides early warning of the population in the affected area and also procuring material and technical equipment DHZ in villages Beautiful Ves , Slatinka nad Bebravou, dart ...
Voir le projet
4
Participants partenaires
TERMINÉ
Karstic agroturism (AGROTUR)
Date du début: 30 sept. 2011, Date de fin: 29 sept. 2014,
Cross-border integration in the karst environment on the content level in the field of agro-tourism. Expected Results: Formation of a new brand "Kras-destination for indigenous products"
Voir le projet
6
Participants partenaires
TERMINÉ
Intestinal stem cells and their role in colorectal cancer progression (CSC program)
Date du début: 1 juin 2010, Date de fin: 31 mai 2012,
...d from ISCs or differentiated cells will be studied using a novel transgenic mouse model system: Starting from defined, targeted cells which have acquired Wnt activation combined with mutation in KRAS, tumor progression can be tracked by fluorescent proteins concomitantly induced with compound mutations. “State-of the art” flow-cytometry-based sorting techniques will be used to isolate different t ...
Voir le projet
2
Participants partenaires
TERMINÉ
Implementation of sustainable groundwater use in the underground karst system of the Krásnohorská jaskyÅa Cave (KRASCAVE)
Date du début: 1 juin 2012, Date de fin: 31 déc. 2018,
Background
Slovakian groundwater resources have experienced significant depletions (by as much as 35%) since 1980. The problem is particularly acute in the area of the Slovak Karst. Intensification of agriculture and forestry have played parts in destabilising traditional hydrological systems and led to landscape changes as well as flooding issues that af ...
Voir le projet
5
Participants partenaires
TERMINÉ
Second Wave
Date du début: 1 janv. 2014,
... was succesfully used in this city. Meanwhile the Gouda youth were very interested in the Debate in the neighborhood approach in Antwerp. So an exchange took place and the Youth umbrella organisation KRAS decided with the youth to continue with this. It was a great achievement that the KRAS youth work even integrated this process of 'Wij(k) in Verandering' , with a focus on improved relations betw ...
Voir le projet
6
Participants partenaires
TERMINÉ
SPIRALING the IMAGINATIVE
Date du début: 31 mai 2016, Date de fin: 30 déc. 2016,
...ece that is open for people from the local community to experience what the possibilities are of SLT. We will also invite targeted youth workers and youth-organisations: Uit de Marge, Habbekrats, Kras, Jonge Helden and more. Also will each partner organisation write a report of /article about their participation in the mobility project, which they will publish on their website and/or in their news ...
Voir le projet
5
Participants partenaires
TERMINÉ
Functional in vivo analysis of cholangiocarcinoma development, progression and metastasis. (CholangioConcept)
Date du début: 1 sept. 2015, Date de fin: 31 août 2020,
... mouse models and stable in vivo shRNA technology, we here propose a comprehensive and innovative approach to i) dissect molecular mechanisms of cholangiocarcinogenesis, with a particular emphasis on Kras driven ICC development from adult hepatocytes and oncogenomic profiling of ICC metastasis, ii) to employ direct in vivo shRNA screening to functionally identify new therapeutic targets for CCC tr ...
Voir le projet
1
Participant partenaire
TERMINÉ
Supplying lung adenocarcinoma cell lines to the cancer research community. (SLACC)
Date du début: 1 nov. 2015, Date de fin: 31 oct. 2016,
...sseminating and exploiting a novel method for generating an unlimited pool of such lines from various strains of mice. Human lung cancer is characterized by a variety of mutations in oncogenes (i.e., KRAS) and tumor suppresors (i.e., TRP53), which largely determine whether lung tumors respond to a given therapeutic regime. Human lung cancer cell lines are invaluable for in vitro studies, but need ...
Voir le projet
1
Participant partenaire
TERMINÉ
Reliable Novel Liquid Biopsy technology for early detection of colorectal cancer (Liqbiopsens)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2018,
The overall aim of LIQBIOPSENS project is the further development and validation in real settings of a novel diagnostic platform for the early and fast detection of ctDNA and their KRAS and BRAF mutations associated to colorectal cancer through blood samples. The main features of LIQBIOPSENS are: reliability (detection rates vary from 95–100 %), low-cost (40-50 € per sample analysis), sensitivity ...
Voir le projet
7
Participants partenaires
TERMINÉ
Membrane Potential and Stem Cell Potency in Normal and Malignant Tissues (MPSC)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,
...1 locus: Promin1 marks stem and progenitor cells in several organs. Focusing on the gastric mucosa we showed that this tissue is regenerated by normal Promin1 stem cells and forms gastric cancer when Kras and Tp53 mutations are introduced into these cells. Remarkably, comparison of the transcriptomes of normal and malignant Promin1+ gastric stem cells revealed a selective silencing of ion channel ...
Voir le projet
1
Participant partenaire
TERMINÉ
Targeting downstream effectors of Wnt signaling in colorectal cancer (ColonCan)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,
...which is required for phenotypes causes by Apc loss.However, despite the clear importance of APC loss and deregulated Wnt signalling, additional events are required for the development of CRC such as KRAS and P53 mutations.The impact of these changes on the development of CRC and response to therapy is not well understood. Furthermore, identification and testing of potential novel targets and ther ...
Voir le projet
1
Participant partenaire
TERMINÉ
Systems analysis of pancreatic tumor cell phenotype dependence on the spatial regulation of oncogenic Ras signaling (SPATONC)
Date du début: 1 avr. 2013, Date de fin: 31 mars 2018,
...rference with spatial cycles, that normally maintain all major Ras isoforms on the plasma membrane, affects the signaling output from oncogenic Ras and thereby inhibits the growth and survival of KRas transformed murine pancreatic cancer cells. The purpose of the proposed multi-disciplinary project is to quantitatively assess in situ how the spatial organization of KRas affects the state of intrac ...
Voir le projet
1
Participant partenaire
TERMINÉ
Targeting RAS oncogene addiction (RASTARGET)
Date du début: 1 mai 2013, Date de fin: 30 avr. 2018,
Lung cancer is the most common type of malignant tumour worldwide and the leading cause of cancer-related death (335,000 deaths per year in Europe). The KRAS oncogene is frequently activated by point mutation in human lung cancer and mutations in the RAS family oncogenes are responsible for driving some 20% of all human malignancies. Most cell lines from RAS mutant tumours remain “oncogene addicte ...
Voir le projet
2
Participants partenaires
TERMINÉ
Systemic analysis of chromatin-regulatory genes in PDAC using advanced in vivo RNAi (EPI-TARGETS IN PDAC)
Date du début: 1 juil. 2013, Date de fin: 30 juin 2015,
... time remains unchanged at only 6 months. PDAC arises from complex and heterogeneous genetic aberrations, which in a single case typically involve >50 genes. Besides four hallmark mutations affecting KRAS, TP53, CDKN2A and SMAD4, aberrations of the chromatin regulatory machinery are common in PDAC. Chromatin-associated genes are particularly attractive as drug targets, since resulting epigenetic a ...
Voir le projet
1
Participant partenaire
TERMINÉ
New approaches for the targeted therapy of Non-Small Cell Lung Cancer (LUNGTARGET)
Date du début: 1 janv. 2011, Date de fin: 30 juin 2015,
Lung cancer is the most common cancer fatality in Europe (335000 deaths/yr). Non-small cell lung cancer (NSCLC) consists 85% of the cases, with 5 yr survival
Voir le projet
10
Participants partenaires
TERMINÉ
Investigation of a dependency of RAS-driven cancers on matrix metalloproteinase-7 (RAS and MMP7)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2012,
...s necessary for the RAS-driven oncogenic state. This approach has led to the identification of the matrix metalloproteinase-7 (MMP-7) as a protein required for the survival of cells with an activated KRAS allele. MMP-7 is a member of the matrix metalloproteinase family that has broad substrate selectivity against extracellular matrix components and some non-matrix substrates. MMP-7 is overexpresse ...
Voir le projet
1
Participant partenaire
TERMINÉ
EDUGATE - Multilingual teaching in early childhood education and care
Date du début: 1 sept. 2016, Date de fin: 31 août 2019,
...e 7, representatives of the following countries: Italy (the applicant, Municipality of Piacenza and the University of Milano-Bicocca), Czech Republic (ZA ANGEL), Latvia (Riga Municipality), Poland (Krasne Municipality), Slovenia (FINI Institute) and Sweden (Univeristy of Goteborg).The activities foreseen are:– A research phase directly involving pre-school teachers/educators to collect their op ...
Voir le projet
7
Participants partenaires
TERMINÉ
Feasibility study for a European Forum for Enhanced Collaboration in Teaching
Date du début: 1 déc. 2015, Date de fin: 30 nov. 2018,
The “Feasibility Study for a European Forum for Enhanced Collaboration in Teaching” (EFFECT) aims at assessing the potential of a European level structure that would contribute to enhancing higher education teaching. It addresses the needs of teaching practitioners, universities and organisations and networks dedicated to teaching enhancement. The three-year project is led by the European Universi ...
Voir le projet