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 TERMINÉ 
Our main objective is to identify determinants of brain, cognitive and mental health at different stages of life. By integration, harmonisation and enrichment of major European neuroimaging studies of age differences and changes, we will obtain an unparalleled database of fine-grained brain, cognitive and mental health measures of more than 6.000 individuals. Longitudinal brain imaging, genetic an ...
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 16

 TERMINÉ 

The listening challenge: How ageing brains adapt (AUDADAPT)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Humans in principle adapt well to sensory degradations. In order to do so, our cognitive strategies need to adjust accordingly (a process we term “adaptive control”).The auditory sensory modality poses an excellent, although under-utilised, research model to understand these adjustments, their neural basis, and their large variation amongst individuals. Hearing abilities begin to decline already i ...
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 1

 TERMINÉ 
Optical imaging has exceptional potential for medical diagnosis, because it can provide high spatial resolution and molecular contrast. However, for in vivo imaging in humans, the poor penetration of only a few millimetres is a major obstacle. Optical endoscopes solve this problem, but currently most of them only perform non-advanced, classical white light imaging. Also, the speed of current devic ...
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 1

 TERMINÉ 

Systems Medicine of Mitochondrial Parkinson’s Disease (SysMedPD)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,

The overall objective of this project is to identify novel drug candidates capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multi-modal phenotypic characterisation of cohorts of monogenic PD patients with overt mitochondrial dysfunction will be used as an anchor for the discovery of two extreme coh ...
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 8

 TERMINÉ 

Continuous Observation of Embedded Multicore Systems (COEMS)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2019,

The ability to observe the internals of an execution of a computer-based system is a fundamental requirement for ultimately ensuring correctness and safe behaviour. Within COEMS (Continuous Observation of Embedded Multicore Systems) a novel observer platform with supporting verification methods for software systems is created. COEMS tackles the issues of detection and identification of non-determi ...
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 6

 TERMINÉ 

Approximation Methods for Molecular Modelling and Diagnosis Tools (AMMODIT)

Date du début: 1 août 2015, Date de fin: 31 juil. 2019,

This proposal brings together research teams from the EU (Germany, Italy, and Austria) and the Ukraine (Kyiv, Donezk) in the area of applied mathematics with emphasis on medical and life science applications. The goal is joint research in six research tasks concerning the study of mathematical methods for Magnetic Particle Imaging; entropy-like measures and quantification of system complexity; coa ...
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 3

 TERMINÉ 
Survival rates after childhood cancer now reach nearly 80% in developed European countries as a result of more effective therapies and better supportive care, leading to a steady increase in the number of survivors in the population. However, the treatments that have improved survival are harsh and cause serious side-effects that can greatly impact survivors’ quality of life in the long term. The ...
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 19

 TERMINÉ 

Approximation of Functions and Fourier Multipliers and their applications (AFFMA)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2018,

This research project is concerned with the following three topics in approximation theory and Fourier analysis:1) Simultaneous approximation of functions and their derivatives in Lp, 0
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 1

 TERMINÉ 

Dobutamine for NEOnatal CIRCulatory failure defined by novel biomarkers (NEO-CIRC)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2018,

Dobutamine and adrenaline are widely used as second line therapy for systemic hypotension in infants. Dopamine is currently the most widely used first line drug. In neonates, sustained hypotension may, and impaired organ perfusion will, cause brain injury and poor neurodevelopmental outcomes. All three catecholamines are currently used off-label and have different modes of action which may result ...
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 20

 TERMINÉ 

OrganiCity – Co-creating smart cities of the future (OrganiCity)

Date du début: 1 janv. 2015, Date de fin: 30 juin 2018,

OrganiCity offers a new paradigm to European digital city making. Built on and extending the FIRE legacy, this project seeks to build a strong foundation for future sustainable cities through co-creation by a wide range of stakeholders. Globally, Europe is a champion of sustainable, inclusive and open societies. The digital age enables us to push this position further and to rethink the way we cre ...
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 16

 TERMINÉ 

European Medical Information Framework (EMIF)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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 64

 TERMINÉ 

Nanometrology Standardization Methods for Magnetic Nanoparticles (NANOMAG)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

The NanoMag project is to improve and redefine existing analyzing methods and in some cases, to develop new analyzing methods for magnetic nanostructures. Using improved manufacturing technologies we will synthesize magnetic nanoparticles with specific properties that will be analyzed with a multitude of characterization techniques (focusing on both structural as well as magnetic properties) and b ...
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 18

 TERMINÉ 

nEUROinflammation

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

Neuroinflammation is a hallmark of multiple sclerosis and ischemic stroke. Investigating neuroinflammation as a common theme in neurological disorders, this ITN will focus in particular on myeloid cells, microglia, and endothelial cells. Sixteen partners from the academic and private sector with complementary scientific background join forces to train 13 ESRs in neuroinflammatory concepts and tech ...
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 13

 TERMINÉ 
StemBANCC, comprising internationally renowned investigators, is ideally positioned to deliver a unique European biorepository and drug discovery pipeline based upon human induced pluripotent stem cells (hiPSC). This unrivalled opportunity will address the pressing therapeutic need in neurodegeneration, neurodysfunction and diabetes. We have immediate access to richly phenotyped subjects with a we ...
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 38

 TERMINÉ 
Cardiogenic shock (CS) complicating acute myocardial infarction (AMI) represents a major European health care concern with mortality rates between 40-70%. Approximately 70-80% of these patients present with multivessel disease defined as coronary lesions in more than one vessel. The clinician is faced with the decision to either 1) intervene only on the culprit lesion acutely responsible for the i ...
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 23

 TERMINÉ 

European Multicentre Tics in Children Studies (EMTICS)

Date du début: 1 déc. 2011, Date de fin: 31 mai 2017,

This project will undertake pre-clinical and cohort studies that address susceptibility factors for paediatric and adolescent tic disorders, with a particular focus on comorbid obsessive-compulsive symptomatology, from clinical, epidemiological, genetic, microbiological and immunological angles. EMTICS aims to elucidate the complex aetiology of the onset and clinical course of chronic tic disorder ...
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 33

 TERMINÉ 
Disorders of sex development (DSD) are a conglomerate of rare diseases with an estimated incidence of 1: 4500. The causes of DSD are mainly disorders with gonadal dysgenesis, decreased androgen synthesis or function in XY males or disorders with elevated androgen production in XX females. Decision on sex of rearing is difficult in some cases as the prenatal androgen imbalances result in ambiguous ...
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 17

 TERMINÉ 
Atherosclerosis and its most disabling sequelae, coronary artery disease (CAD) and stroke, are leading causes of death in Europe. Until now, preventive and therapeutic interventions for these diseases aim at ameliorating the effects of established cardiovascular risk factors. More recently, results of genome-wide association (GWA) studies added to our perception of mechanisms leading to atheroscle ...
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 13

 TERMINÉ 

Biomarker for Cardiovascular Risk Assessment in Europe (BiomarCaRE)

Date du début: 1 oct. 2011, Date de fin: 31 mars 2016,

Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role in the drive towards personalised medicine remains uncertain.Based on harmonised and standardised European population cohorts we have built significant research collabo ...
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 31

 TERMINÉ 

EU-Ukrainian Mathematicians for Life Sciences (EUMLS)

Date du début: 1 avr. 2012, Date de fin: 31 mars 2016,

"The goal of the project is to establish a structured and sustainable research partnership of mathematicians working on applications in life sciences, consisting of researchers from Ukraine as an eligible ICPC country and several research groups from EU member states and associated countries (MS/AC).There is a sizable – but currently still unstructured – group of Ukrainian researchers from various ...
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 4

 TERMINÉ 

Targeting Norovirus Receptor Interactions at Atomic Resolution (NoroCarb)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2015,

Norovirus infections affect more than 200 million people worldwide every year. Since these viruses are highly contagious and cause epidemic outbreaks norovirus infections constitute a massive economic burden. Currently there are neither vaccination strategies nor therapeutics to cure the infection. We have designed first prototype entry-inhibitors against norovirus infections employing a rational ...
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 1

 TERMINÉ 

Small-molecule Inhibitor Leads Versus emerging and neglected RNA viruses (SILVER)

Date du début: 1 oct. 2010, Date de fin: 31 mars 2015,

RNA virus infections kill millions of humans annually, largely due to the lack of suitable vaccines and drugs to control them. This problem is addressed in this FP7 call and in response a consortium of Europe’s and Asia’s leading molecular virologists, structural biologists, medicinal chemists and bioinformaticians has been brought together to generate a state-of-the-art drug discovery and design ...
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 25

 TERMINÉ 

European Project on Mendelian Forms of Parkinson’s Disease (MEFOPA)

Date du début: 1 avr. 2010, Date de fin: 30 sept. 2013,

"The Collaborative Project on Mendelian Forms of Parkinson’s Disease (MEFOPA) will bring together the major groups in Europe with a track-record in basic and clinical research on rare Mendelian forms of Parkinson’s disease (PD) in order to identify and validate relevant disease-related molecular pathways, drug-targets and biomarkers for disease susceptibility and progression.. Over the last years ...
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 27

 TERMINÉ 

Integrated Interventional Imaging Operating System (IIIOS)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,

...equire a range of safe surgical and interventional devices used with the necessary visualization and tracking under real-time image guidance. The consortium includes a critical mass of industrial and university research institute partners with high expertise in design, development, and manufacture of these devices and instruments. To ensure medical the safety and economical usability of the system ...
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 13

 TERMINÉ 

Affording Recovery In Stroke (ARISE)

Date du début: 1 mars 2008, Date de fin: 31 août 2013,

"Stroke poses a massive clinical, social and economic burden, yet we have very limited effective therapies. This inadequacy is in spite of intensive research efforts and numerous failed clinical trials. Leading European stroke researchers and clinicians with a track record of established cooperation will share their complementary expertise, and team up with SME partners with high profile R&D and o ...
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 17

 TERMINÉ 

Future Internet Research and Experimentation SupporT AcTION (FIRESTATION)

Date du début: 1 juin 2010, Date de fin: 31 mai 2013,

FIRE STATION provides the globally known FIRE (Future Internet Research and Experimentation) Initiative with an active hub that matches, guides and co-ordinates demand for - and offering of - experimentation facilities in the context of future networks and services. The heterogeneous and modular field of Future Internet Research and Experimentation with its national and international stakeholder g ...
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 8

 TERMINÉ 

European Network for Genetic and Genomic Epidemiology (ENGAGE)

Date du début: 1 janv. 2008, Date de fin: 31 déc. 2012,

"ENGAGE (European Network for Genetic and Genomic Epidemiology) has, as its central objective, the translation of the wealth of data emerging from large-scale research efforts in molecular epidemiology into information of direct relevance to future advances in clinical medicine. ENGAGE will do this through the integration of very large-scale genetic and phenotypic data already available from a sub ...
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 26

 TERMINÉ 
The social capacity, knowledge and acceptance to utilise eHealth technologies of citizens and medical professionals is a basic condition for the implementation and further generation of innovative technologies for the health sector. However, the absorption of new knowledge and acceptance to use eHealth technologies is varying remarkably among citizens and medical professionals and needs to be stre ...
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 19

 TERMINÉ 

Internet of Things Initiative (IoT-i)

Date du début: 1 sept. 2010, Date de fin: 30 nov. 2012,

Internet of Things (IoT) is one of the most important areas of a Future Internet with significant potential to positively impact European economy and society. The current IoT research community is however highly fragmented, featuring diverging approaches and technologies. This inevitably leads to a lack of coherency that hinders the realisation of an interoperable IoT, preventing the IoT to achiev ...
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 17

 TERMINÉ 

Functional optical coherence tomography (FUN OCT)

Date du début: 1 avr. 2008, Date de fin: 30 sept. 2012,

"The aim of FUN OCT is to expand the non-invasive optical biopsy capability of optical coherence tomography (OCT) and combination of OCT with multiphoton tomography (MT) to develop novel functional capabilities hereby enabling ‘morphofunctional’ performance, i.e., the fusion of anatomic and functional imaging at the cellular resolution level. These methodologies will enable unprecedented non-invas ...
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 7

 TERMINÉ 
"The overall objective of this proposal is to develop and validate a quantitative, minimally invasive diagnostic tool for early and conclusive detection, diagnosis and monitoring of disease and disease progression of breast and prostate cancer. A methodology will be developed making use of a combination of the probably most exciting recent advances in the field of light microscopy, for fluorescenc ...
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 12

 TERMINÉ 

BaltFood - The BSR Food Cluster: Innovation and Competitiveness in Action (BaltFood)

Date du début: 31 déc. 2008, Date de fin: 23 janv. 2012,

BaltFood integrates local, regional and national food cluster organisations in six countries around the Baltic Sea into one food cluster. The cooperation focuses on enhancing the competitiveness of the BSR food industry to become the European source for valuable and affordable food products. The food industry has developed into one of the strongest business sectors in the BSR characterized by high ...
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 13

 TERMINÉ 
Disorders of Sex Development (DSD) constitute a group of rare to very rare mostly heritable disorders affecting the genito-urinary tract and in most instances also the endocrine-reproductive system. We hypothesize that stringent and stepwise analysis of cases with DSD will result in a systematic and reliable discovery of DSD-relevant biochemical, genetic and functional profiles, allowing for the d ...
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 14

 TERMINÉ 
Description Robots endowed with neural/computational mechanisms and sensorimotor systems structurally similar to human beings The ROSSI project addresses the question how the possibility of communication between agents (e.g. humans and robots) is affected by differences in sensorimotor capacities. ...
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 7

 TERMINÉ 

Wireless Sensor Network Testbeds (WISEBED)

Date du début: 1 juin 2008, Date de fin: 31 mai 2011,

The aim of this project is to provide a multi-level infrastracture of interconnected testbeds of large-scale wireless sensor networks for research purposes, pursuing an interdisciplinaryapproach that integrates the aspects of hardware, software, algorithms, and data. This will demonstrate how heterogeneous small-scale devices and testbeds can be brought together to form well-organized, large-scale ...
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 9

 TERMINÉ 

Foundations of Adaptive Networked Societies of Tiny Artefacts (FRONTS)

Date du début: 1 févr. 2008, Date de fin: 30 avr. 2011,

In the near future, it is reasonable to expect that new types of systems will appear, designed or emerged, of massive scale, expansive and permeating their environment, of very heterogeneous nature, and operating in a constantly changing networked environment. We expect that most such systems will have the form of a large society of networked artifacts that are small, have limited sensing, signal ...
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 11

 TERMINÉ 

LogVAS - Logistic potentials for value added services in port-located areas (LogVAS)

Date du début: 31 août 2005, Date de fin: 28 févr. 2008,

The traffic flow in the Baltic Sea Region rises immediately and several studies forecast an ongoing dynamic growth in the upcoming years. Ports can benefit from this growth if they do not serve as water-gates only but also create Value Added Services (VAS) on the goods handled. In order to implement the most efficient VAS in the respective ports it is vital to acquire information regarding the kin ...
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 26

 TERMINÉ 

Integrating Logistics Centre Networks in the Baltic Sea Region (InLoC)

Date du début: 31 juil. 2004, Date de fin: 30 mars 2007,

As a follow up of the project NeLoC projecz InLoc aimed at further improvement of the networking between logistics centres, ports and other logistics operators in the Baltic Sea Region. The project also analysed spatial and environmental consequences of logistics centres and aimed at removing bottlenecks in port-hinterland connections. Furthermore, the project tried to improve the compatibility of ...
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 35

 TERMINÉ 
The project was aiming at the improvement of planning processes by improving the transregional communication and decision structures. The outcome of the project is a thematic network and a centre of excellence for improving the political (e.g. spatial planning authorities, municipalities, ministries, Governmental and Non-Governmental-Organisations) and entrepreneurial policy-making-processes in th ...
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 14

 TERMINÉ 
CaseMaker is a transversal project aiming to promote new learning and teaching practices in higher education and secondary vocational education using an open source web-based ICT-platform specifically designed to enhance case-based teaching and learning. The ICT-platform will build on the technology and experiences of Shareville, and Moodle platforms developed and used by the partners. The overall ...
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 7