Plus de 40 projets européens trouvés
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TERMINÉ
No stress with pArg: Mechanisms of a distinct phospho-mark to coordinate stress response and protein quality control (pArg_deg_signal)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,
Cellular proteins are prone to misfolding and aggregation, particularly under harsh environmental conditions. To counteract this danger, all organisms from bacteria to humans evolved sophisticated protein quality control networks. The mechanisms employed in them tend to represent some of the most exciting biochemistry occurring in living cells.In Gram-positive bacteria, the key factors combating p ...
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2
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TERMINÉ
Molecular mechanisms of cohesin-mediated sister chromatid cohesion and chromatin organization (CohesinMolMech)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,
During S-phase newly synthesized “sister” DNA molecules become physically connected. This sister chromatid cohesion resists the pulling forces of the mitotic spindle and thereby enables the bi-orientation and subsequent symmetrical segregation of chromosomes. Cohesion is mediated by ring-shaped cohesin complexes, which are thought to entrap sister DNA molecules topologically. In mammalian cells, c ...
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2
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TERMINÉ
Comorbidity and Synapse Biology in Clinically Overlapping Psychiatric Disorders (COSYN)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
COSYN integrates outstanding European academic and three large Pharma to exploit genomic findings for intellectual disability (ID), autism, and schizophrenia. We capitalise on comorbidity, from clinic to cells and synapses, and have access to large existing samples. We focus on rare genetic variants of strong effect in patients with clinical comorbidity. Our aims are: (1) Understand comorbidity by ...
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14
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TERMINÉ
Training, Research and Raising of Public Awareness in Cell Biology and Pathology of Neuroglia (EU-GliaPhD)
Date du début: 1 déc. 2016, Date de fin: 30 nov. 2020,
The research in which the young scientists of the EU-GliaPhD consortium will be trained is centred on the role of neuron-glia interactions in brain function and pathology.Prompted by exciting discoveries of recent years, many academic research groups are currently focussing their research on the field of neuron-glia interactions for a better understanding of brain function. Also the private sector ...
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13
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TERMINÉ
Fishfriendly Innovative Technologies for Hydropower (FIThydro)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
FIThydro addresses the decision support in commissioning and operating hydropower plants (HPP) by use of existing and innovative technologies. It concentrates on mitigation measures and strategies to develop cost-efficient environmental solutions and on strategies to avoid individual fish damage and enhancing population developments. Therefore HPPS all over Europe are involved as test sites. The f ...
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26
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TERMINÉ
Identification and functional characterization of mammalian enhancers and transcriptional co-factors during cellular signaling and cell fate transitions (Enhancer ID)
Date du début: 1 sept. 2015, Date de fin: 31 août 2020,
A major goal in biology is to understand how gene regulatory information is encoded by the human genome and how it defines different gene expression programs and cell types. Enhancers are genomic elements that control transcription, yet despite their importance, only a minority of enhancers are known and functionally characterized. In particular, their activity changes during cellular signalling o ...
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2
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TERMINÉ
Pharmaceutical Education And Research with Regulatory Links: Innovative drug development strategies and regulatory tools tailored to facilitate earlier access to medicines (PEARRL)
Date du début: 1 mai 2016, Date de fin: 30 avr. 2020,
The European Pharma industry is a major contributor to EU well-being, both in public health and economic (sales >200 billion €/year) terms. To maintain global leadership, it must respond to challenges from low-cost producers e.g. China by bringing new drug molecules to market in a streamlined, cost-effective manner. This strategy is underscored by recent initiatives of European regulators to exped ...
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9
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TERMINÉ
Clinical study in Parkinson's disease with two unique goals: 1) Proof-of-concept of CDNF protein for disease modification; 2) Validation of clinically tested device for intracerebral drug delivery (TreatER)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,
The main focus of TreatER is conducting a randomized, placebo-controlled, first-in-human, proof-of-concept, safety and efficacy study of intracerebrally administered CDNF protein therapy in patients with Parkinson’s disease (PD), using a neurosurgically implanted Drug Delivery System (DDS), which will also be clinically validated in the study. Thus the TreatER project has two independent goals, ei ...
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12
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TERMINÉ
Reintroduction of burning in Boreal western taiga woodlands (LifeTaiga)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,
Background
Controlled burning can support the conservation of many sites of priority habitat type 9010 (*Western Taïga) and, to some extent, habitat 9060 (Coniferous forests on, or connected to, glaciofluvial eskers) Up until 150 years ago, 1% of the wooded area burned annually. Today less than 0.016% burns annually. The reduction in the frequency of fir ...
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14
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TERMINÉ
European Prevention of Alzheimer’s Dementia Consortium (EPAD)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,
Background:The secondary prevention of Alzheimer’s dementia (AD) is achievable if we can identify individuals at risk of disease progression defined by biomarker evidence of AD pathology and no or only minimal clinical symptoms and engage them in a standing adaptive clinical trial, of the highest quality, testing multiple interventions. To achieve this, EPAD will also provide the analytical infras ...
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40
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TERMINÉ
Management Of Networked IoT Wearables – Very Large Scale Demonstration of Cultural Societal Applications (MONICA)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,
The SoundCity Project MONICA aims to provide a very large scale demonstration of multiple existing and new Internet of Things technologies for Smarter Living. The solution will be deployed in 6 major cities in Europe.MONICA demonstrates a large scale IoT ecosystem that uses innovative wearable and portable IoT sensors and actuators with closed-loop back-end services integrated into an interoperab ...
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28
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TERMINÉ
My Health - My Data (MH-MD)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2019,
Issues of data subjects’ privacy and data security represent a crucial challenge in the biomedical sector more than in other industries. The current IT landscape in this field shows a myriad of isolated, locally hosted patient data repositories, managed by clinical centres and other organisations, which are subject to frequent and massive data breaches. Patients are disenfranchised in this process ...
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16
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TERMINÉ
REady for BUSiness - Integrating and validating practical entrepreneurship skills in engineering and ICT studies
Date du début: 15 oct. 2016, Date de fin: 14 oct. 2019,
European business sector pays an ever more increasing attention to competences such as sense of initiative and entrepreneurship. The recommendation 2006/962/EC on key competences for lifelong learning highlights paramount importance of these key competences for employability. These competences related to entrepreneurship play a paramount role in EU neighbouring countries in their development proc ...
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14
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TERMINÉ
Collaboration Network for Industry, Manufacturing, Business and Logistics in Europe (NIMBLE)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2019,
NIMBLE: collaboration Network for Industry, Manufacturing, Business and Logistics in Europe will develop the infrastructure for a cloud-based, Industrie 4.0, Internet-of-things-enabled B2B platform on which European manufacturing firms can register, publish machine-readable catalogs for products and services, search for suitable supply chain partners, negotiate contracts and supply logistics, and ...
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17
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TERMINÉ
NEXUS 1492. New World Encounters in a Globalising World (NEXUS1492)
Date du début: 1 sept. 2013, Date de fin: 31 août 2019,
NEXUS1492 investigates the impacts of colonial encounters in the Caribbean, the nexus of the first interactions between the New and the Old World. This Synergy Programme intends to rewrite a crucial and neglected chapter in global history initiated by European colonisation by focussing on transformations to indigenous, Amerindian cultures and societies. NEXUS1492 will address intercultural Amerind ...
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3
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TERMINÉ
Next generation urban mining - Automated disassembly, separation and recovery of valuable materials from electronic equipment (ADIR)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
Specific raw materials become increasingly important to manufacture high level industrial products. Especially electronic equipment contains precious metals and a series of strategic raw materials. To date the material specific recycling is focused on mass stream concepts such as shredder processes and metallurgy to extract the high-value metallic constituents, i.e. copper, gold, silver. However, ...
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10
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TERMINÉ
INTEGRATED AND ADAPTIVE RESPONSES TO TOXIC EMERGENCIES FOR RAPID TRIAGE: ENGINEERING THE ROADMAP FROM CASUALTY TO PATIENT TO SURVIVOR. (TOXI-triage)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
The seven specific objectives of TOXI-triage address the operational; technological; ethical and societal dimensions of CBRN response and recovery, and importantly the economic base from which sustainable CBRN and multi-use systems are derived.19 partners in 4 Task forces will deliver 9 Work Packages (WPs) that address: end user specifications; Design and delivery; Test and Validation; and, Impact ...
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19
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TERMINÉ
POWER2DM - Predictive model-based decision support for diabetes patient empowerment (POWER2DM)
Date du début: 1 févr. 2016, Date de fin: 31 juil. 2019,
The main objective of POWER2DM is to develop and validate a personalized self-management support system (SMSS) for T1 and T2 diabetes patients that combines and integrates (1) a decision support system (DSS) based on leading European predictive personalized models for diabetes interlinked with predictive computer models, (2) automated e-coaching functionalities based on Behavioural Change Theories ...
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8
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TERMINÉ
LNG PILOTS
Date du début: 15 janv. 2016, Date de fin: 30 juin 2019,
De introductie van LNG als nieuwe brandstof en energiebron voor de industrie brengt een onder-zoeks- en ontwikkelingsbehoefte met zich mee. Investeringen op dit gebied zullen de kwaliteit van de regionaal gevestigde onderzoeksinstellingen ten goede komen en de vestiging van hoogwaardige technologische ondernemingen op het gebied van logistiek, voertuigbouw, scheepsbouw, energietechniek en energiev ...
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36
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TERMINÉ
The Cellular and Molecular Basis of Magnetoreception (CeMoMagneto)
Date du début: 1 avr. 2014, Date de fin: 31 mars 2019,
Each year millions of animals undertake remarkable migratory journeys, across oceans and through hemispheres, guided by the Earth’s magnetic field. The cellular and molecular basis of this enigmatic sense, known as magnetoreception, remains an unsolved scientific mystery. One hypothesis that attempts to explain the basis of this sensory faculty is known as the magnetite theory of magnetoreception. ...
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1
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TERMINÉ
Elucidating the molecular mechanism of cohesin-loading (Cohesin loading)
Date du début: 1 avr. 2017, Date de fin: 31 mars 2019,
The cohesin-complex mediates sister chromatid cohesion from S-phase until mitosis and is involved in the formation of higher-order chromatin structure. To fulfill these vital functions, cohesin is loaded and positioned in the genome by mechanisms that are only poorly understood. In vitro, loading of cohesin on DNA only requires ATP and a loading-complex formed by Scc2-Scc4, while loading in vivo o ...
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2
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TERMINÉ
Training the Next Generation of European Visual Neuroscientistsfor the benefit of innovation in health care and high-tech industry (NextGenVis)
Date du début: 1 mars 2015, Date de fin: 28 févr. 2019,
The human visual brain can learn and adapt to change, which solves many of the problems posed by an ever-changing visual environment. However, to maintain a consistent overall representation of the visual world, the brain also has to retain previously acquired neuronal mechanisms. The key is to strike a balance between plasticity and stability.Increasing our knowledge about the stability and plast ...
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10
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TERMINÉ
Coordinating for life. Success and failure of Western European societies in coping with rural hazards and disasters, 1300-1800 (COORDINATINGforLIFE)
Date du début: 1 mars 2014, Date de fin: 28 févr. 2019,
Societies in past and present are regularly confronted with major hazards, which sometimes have disastrous effects. Some societies are successful in preventing these effects and buffering threats, or they recover quickly, while others prove highly vulnerable. Why is this?Increasingly it is clear that disasters are not merely natural events, and also that wealth and technology alone are not adequat ...
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1
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TERMINÉ
Spatio-temporal specificity of miRNA function (mirspecificity)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
MicroRNAs are versatile regulators of gene expression and as such, they are essential parts of the gene regulatory networks controlling development and physiology of animals and plants. In particular, a number of miRNAs have been implicated in cell-type differentiation. Adding miRNAs to existing networks in particular subsets of cells can increase the complexity of developmental programs, and thus ...
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1
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TERMINÉ
Knowledge Alliance to enable a European-wide exploitation of the potential of MOOCs for the world of business
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2018,
‘Massive Open Online Courses’ (MOOCs) caused a major impact on HEIs worldwide. Business models, target groups, quality standards, certification, sustainability, teaching, delivery & learning methods are all affected. Europe is yet to respond to these emerging trends. Initiatives in the EU exist, but remain isolated, both geographically and per sector. They lack impact on the HEI area as a whole, a ...
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11
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TERMINÉ
Sport Welcomes Refugees - Social inclusion of newly arrived migrants in and through sport
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2018,
The overall objective of the project “Sport Welcomes Refugees – Social inclusion of newly arrived migrants in and through sport” is to enhance the social inclusion and participation of newly arrived migrants on different levels of sport through training, awareness-raising and capacity-building of sport stakeholders. The project is designed to achieve the following specific objectives: • Facilitate ...
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8
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TERMINÉ
Secure Architectures of Future Emerging Cryptography (SAFEcrypto)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,
SAFEcrypto will provide a new generation of practical, robust and physically secure post quantum cryptographic solutions that ensure long-term security for future ICT systems, services and applications. Novel public-key cryptographic schemes (digital signatures, authentication, public-key encryption, identity-based encryption) will be developed using lattice problems as the source of computational ...
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8
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TERMINÉ
Artist-to-Business-to-Business-to-Consumer Audio Branding System (ABC DJ)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2018,
The current European market for audio branding services is lopsided, both in economic terms as well as in aspects of cultural identity. In the slipstream of big U.S. companies like McDonald's, North American providers have captured the European (and worldwide) market for instore music and have held a strong position ever since. Today the worldwide market is effectively monopolised by two 'big play ...
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7
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TERMINÉ
Systematic in-vivo analysis of chromatin-associated targets in leukemia (ChromatinTargets)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,
Recent advances in genome sequencing illustrate the complexity, heterogeneity and plasticity of cancer genomes. In leukemia - a group of blood cancers affecting 300,000 new patients every year – we know over 100 driver mutations. This genetic complexity poses a daunting challenge for the development of targeted therapies and highlights the urgent need for evaluating them in combination. One gene c ...
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1
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TERMINÉ
Intelligent Assessment of Pharmaceutical in the Environment (IPIE)
Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,
Active pharmaceutical ingredients (APIs) can be released to the natural environment during the manufacturing process, following use by patients or when unused medicines are disposed of. As APIs are biologically active compounds concerns have been raised about the potential effects of APIs in the environment on human and environmental health. Over the past 15 years, a substantial amount of work has ...
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29
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TERMINÉ
Doestage bij (inter)nationale dc's en warehouses in Denemarken
Date du début: 1 déc. 2016, Date de fin: 30 nov. 2018,
In June the pupils from the 7th year ‘Logistics’ head to Taastrup and Greve (Denmark) for an international internship with some logistical providers (mentioned below) over a timespan of three weeks:TAASTRUP:- H. Essers Danmark;- Danske Fragtmaend;- Freja;GREVE:- Blue Water Shipping;- PrimeCargo en- Top-Toy.On starting this project our main goals are:1 to practise and improve technical knowledge an ...
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9
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TERMINÉ
FORMACION EN CENTROS DE TRABAJO EUROPEO
Date du début: 7 nov. 2016, Date de fin: 6 nov. 2018,
In line with the objectives of the Europe2020 Strategy and ET2020, through "EUROFCT", IES Vega de Gudalete, aims to improve the quality of education and vocational training, giving a European dimension to the educational paths and thus providing the young participants the opportunity to test and improve their skills: professionalism in the specific areas of vocational education (informatics micros ...
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16
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TERMINÉ
EUROLABORA III
Date du début: 7 nov. 2016, Date de fin: 6 nov. 2018,
The project arises in a context of crisis and unemployment especially high among young people. Many of them, although they have completed their vocational educational studies and they are able to perform a job, don't have enough foreign language skills, or other professional and personal skills that make them less competitive in a labor market increasingly demanding.The project's main objective is ...
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9
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TERMINÉ
AGROVEGA+
Date du début: 7 nov. 2016, Date de fin: 6 nov. 2018,
In line with the objectives of the Europe2020 Strategy and ET2020, through "AGROVEGA+", the consortium, led by the Lora del Rio Council, aims to improve the quality of education and vocational training, giving a European dimension to the educational paths and thus providing the young participants the opportunity to test and improve their skills: professionalism in the specific areas of vocational ...
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38
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TERMINÉ
Participatory Art for Invisible Communities
Date du début: 1 mai 2016, Date de fin: 31 oct. 2018,
Participatory Art for Invisible Communities” (PAIC) is a multidisciplinary and multimedia participatory art project whose general objectives are to incite cultural regeneration by developing a new sense of cultural identity in a form of RENEWABLE CULTURE – a culture of isolated and / or deprived community that is able to survive and transform places by breathing in vitality, fostering cross-discip ...
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4
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TERMINÉ
Refugees in vocational Training
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2018,
Context and background of the projectThe number of refugees and asylum seekers in Germany and other European countries is increasing. This challenge requires different instruments for fostering their long-term integration, because it cannot be expected that they will be able to get back in their home-countries in the nearer future. Mainly instruments are focused on the satisfaction of basic needs ...
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7
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TERMINÉ
Noise in gene expression as a determinant of virulence of the human pathogen Streptococcus pneumoniae (PneumoCell)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Not all cells in bacterial populations exhibit exactly the same phenotype, even though they grow in the same environment and are genetically identical. One of the main driving forces of phenotypic variation is stochasticity, or noise, in gene expression. Possible molecular origins contributing to noise in protein synthesis are stochastic fluctuations in the biochemical reactions of gene expression ...
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1
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TERMINÉ
PANDORA – Discovering European opportunities for Female Entrepreneurship
Date du début: 31 oct. 2016, Date de fin: 30 oct. 2018,
The project “Pandora – Discovering European opportunities for Female Entrepreneurship” aims to develop and share best practices in the field of adult education. The organizations and institutions involved in the project work in different areas, but every institution/association focus on adult education and social field. The main idea of the project is to develop an educational path for disadvantag ...
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4
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TERMINÉ
GameHub: University-enterprises cooperation in game industry in Ukraine
Date du début: 15 oct. 2015, Date de fin: 14 oct. 2018,
The wider objective of the GameHub project is to ensure employability and self-sustainability of HEI graduates, unemployed engineers as well as veterans of Anti-Terror Operation (ATO) in Ukraine by equipping them with knowledge and skills demanded by digital game industry (GI) - a highly networked global impact economy. GI strongly based on online work approach allows one to develop a highly techn ...
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12
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TERMINÉ
Accessibility and Harmonization of Higher Education In Central Asia through Curriculum Modernization and Development /ACADEMICA/
Date du début: 15 oct. 2015, Date de fin: 14 oct. 2018,
The motivation behind the Project is to bring together European HEIs which possess and supply cutting-edge developments, innovative learning practices and extensive international experience and HEIs from Partner countries in Central Asia/CA/ which need and demand the same developments, practices and experience. The specific problems of Region 7 would be solved by assuring Accessibility and Harmoni ...
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