6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Code-engineered new-to-nature microbial cell factories for novel and safety enhanced bio-production (METACODE)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,
The concept of METACODE is to preform genetic code engineering in microbial strains with parallel recruitment of novel bio-orthogonal chemistries for mass production of desired protein/peptide based products. In combination with computational and classical chemical synthetic approaches as well as chemo-informatics, enzyme guided evolution, synthetic metabolism, and directed evolution of microbial ...
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8
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TERMINÉ
Unbiased Biomarkers for the Prediction of Respiratory Disease Outcomes (U-BIOPRED)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2015,
RationaleThe inability of pre-clinical studies to predict clinical efficacy is a major bottleneck in drug development. In severe asthma this bottleneck results from: a lack of useful and validated biomarkers, underperforming pre-clinical models, inadequate and incomplete sub-phenotyping, and insufficient disease understanding.HypothesisThe use of biomarker profiles comprised of various types of hi ...
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42
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TERMINÉ
Bio-Orthogonal Chemo-Specific Ligation (BioChemLig)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,
The Post-genomic era calls for a deep understanding of protein structure and function. The elucidation of protein structures, localization, post-translation modifications, and protein-macromolecule interactions are important to establish their role in the biology of the cell. To establish their role and investigate the protein functions requires the integration of various complementary disciplines ...
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8
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TERMINÉ
Ankle and Foot Orthotic Personalisation via Rapid Manufacturing (A-FOOTPRINT)
Date du début: 1 oct. 2009, Date de fin: 30 sept. 2013,
Disabling foot and ankle pain is common; it impacts negatively on health related quality of life, and it is has major cost implications on health systems across Europe. Foot and ankle orthoses are an effective treatment for these conditions. However, the market is dominated by low cost mass produced products, craftsmanship built customised devices with delivery times >15 days, and a limited ran ...
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13
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TERMINÉ
A EUROPEAN BIOTECHNOLOGY TRAINING NETWORK FOR THE SUPPORT OF CHEMICAL MANUFACTURING (BIOTRAINS)
Date du début: 1 juil. 2009, Date de fin: 30 juin 2013,
The objective of BIOTRAINS is to deliver a trans-European network of industrially oriented white biotechnologists fully trained in the application of biocatalysis to sustainable chemical manufacturing. Their skills will be developed through a joint research programme at leading national CoE’s (Centre of Excellence) with research projects identified by internationally leading Principal Investigator ...
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13
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TERMINÉ
Genetic DIversity of AVIdins for Novel Biotech Applications (DIVA)
Date du début: 1 oct. 2008, Date de fin: 30 sept. 2011,
"Avidins are amongst the most widely used proteins in biotechnology, with applications encompassing molecular labelling, purification & detection, as well as uses in diagnostics, targeted drug delivery and nanotechnology, such as enantioselective catalysis by artificial catalysts. Avidins also serve as outstanding model systems for our understanding of biomolecular interactions, through their extr ...
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