2 projets européens trouvés
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TERMINÉ
Standarization and orthogonalization of the gene expression flow for robust engineering of NTN (new-to-nature) biological properties (ST-FLOW)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,
The ST-FLOW Project merges the efforts of 14 leading European research groups for developing material and computational standards that enable the forward-design of prokaryotic systems with a degree of robustness and predictability that is not possible with customary Genetic Engineering. The central issue at stake is the identification and implementation of rules that allow the conversion of given ...
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TERMINÉ
Code-engineered new-to-nature microbial cell factories for novel and safety enhanced bio-production (METACODE)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,
The concept of METACODE is to preform genetic code engineering in microbial strains with parallel recruitment of novel bio-orthogonal chemistries for mass production of desired protein/peptide based products. In combination with computational and classical chemical synthetic approaches as well as chemo-informatics, enzyme guided evolution, synthetic metabolism, and directed evolution of microbial ...
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