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38 projets européens trouvés

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 EN COURS 
EmERGE will develop a mHealth platform to enable self-management of HIV in patients with stable disease. The platform will build upon and integrate the existing mHealth solutions operated by pioneering healthcare providers in the UK and Spain and apply a rigorous co-design approach to ensure patient and clinician input to the solution. The platform will provide users with web based and mobile devi ...
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 13

 TERMINÉ 
Background:Type 2 diabetes mellitus (T2DM) and pre-diabetes contribute increasingly to the global burden of disease with the health systems struggling to effectively manage prevention and control. This necessitates contextually appropriate, policy relevant solutions with high scale-up potential. The study is built on a consortium experienced in implementation and cross-cultural translation of dise ...
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 6

 TERMINÉ 

Control of leishmaniasis, from bench to bedside and community (EUROLEISH-NET)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Leishmaniasis control is the topic for EUROLEISH-NET, a Marie Sklodowska-Curie – Innovative Training Network. Leishmaniasis is a neglected infectious disease and a major public health and veterinary problem that afflicts both developing countries and Europe. The current technological and epidemiological advances underpin the necessity to develop training programmes aiming at developing new tools a ...
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 9

 TERMINÉ 
Health services fragmentation is one of the main obstacles to effective health care in Latin-America, particularly for chronic diseases. This research builds upon results from Equity-LA (FP7-B-223123) and focuses on one of the most promoted policies to respond to fragmentation in LA, the development of Integrated Health Care Networks (IHN). The general objective is to evaluate the effectiveness of ...
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 9

 TERMINÉ 
"The overall aim of the proposed staff exchange programme is to establish a long lasting collaboration between Moroccan, South African and European research teams involved in clinical epidemiological and public health research. This effort should ultimately lead to improved mother and child health and better control of sexual transmitted diseases. The proposal is therefore structured in seven work ...
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 7

 TERMINÉ 
"Excessive delays in treatment onset limit current tuberculosis (TB) control programs, presenting a major obstacle to the control of the TB epidemic. Increasing case detection, both quantitatively and temporally, is considered a priority, benefiting the patient (reduced morbidity and mortality) and the society (shortened period of infectiousness). These improvements in patient care have a common g ...
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 2

 TERMINÉ 
To find a therapy alternative to cART for life is one of the hot topics of investigation in HIV field. Therapeutic vaccination seems to be the best option. We have reported in a double-blind placebo controlled study some of the best, most solid data showing that HIV-1 specific immune responses elicited by therapeutic dendritic cell (DC) vaccines pulsed ex vivo with inactivated autologous whole vir ...
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 8

 TERMINÉ 

European Research Infrastructure on Highly Pathogenic Agents 2 (ERINHA2)

Date du début: 1 janv. 2016, Date de fin: 30 juin 2017,

ERINHA2 aims to complete the work carried out during the first preparatory phase (PP1) - ERINHA - in order to reach the financial, administrative and technical maturity necessary to complete the establishment of the Research Infrastructre and ensure that the operation phase can begin in 2018. ERINHA2 will therefore finalise the decision to use the status of an association and prepare the necessary ...
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 17

 TERMINÉ 
Pregnant women are very susceptible to malaria infection and Malaria in Pregnancy (MiP) is a major cause of maternal anaemia and low birth weight (LBW) that leads to infant mortality, poor growth and development. In low transmission areas, malaria can become severe, resulting in maternal and foetal death. In sub-Saharan Africa (SSA) MiP is responsible for 8–14% of LBW, 3–8% of infant deaths, highe ...
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 9

 TERMINÉ 
Visceral leishmaniasis (VL) is fatal if left untreated; East Africa is one of the key endemic areas in the world. Untreated patients are part of the retransmission cycle and VL-HIV co-infection is an additional emerging problem.Existing VL monotherapies are difficult to administer, toxic, costly and long with emerging resistance. Sodium stibogluconate and paromomycin (SSG&PM) has been developed as ...
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 6

 TERMINÉ 
"The tsetse fly (Glossina spp.) salivary gland is the final micro-environment where the Trypanosoma brucei parasites adhere and undergo a complex re-programming cycle resulting in an end stage that is re-programmed to continue its life cycle in a new mammalian host. The molecular parasite-vector communications that orchestrate this trypanosome development in tsetse fly salivary glands remain unkno ...
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 1

 TERMINÉ 
The objective of this proposal is to urgently determine the efficacy, safety and feasibility of convalescent whole blood (CWB) and convalescent plasma (CP) therapy, as a treatment for patients with Ebola Viral Disease (EVD) to reduce the case fatality rate in the present EVD epidemic in West Africa. The trial will take place in three consecutive phases; i) initial phase to initiate harmonized stan ...
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 8

 TERMINÉ 
Neglected Infectious Diseases (NID) such as trypanosomiasis, leishmaniasis, schistosomiasis and soil-transmitted helminthiasis receive less than 5% of the global investment for tropical diseases research. Clinical praxis in disease-endemic countries (DEC) is rarely evidence based and does not make use of the latest innovations in diagnostic technology. NID–related research on diagnostics is partic ...
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 13

 TERMINÉ 
"The goal of universal health coverage is receiving growing attention. How best to improve risk pooling and to ensure that the most socially disadvantaged receive priority in having their health care costs met, are questions yet to be answered, particularly within the African context where very few countries have achieved universal health systems. South Africa is introducing National Health Insura ...
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 7

 TERMINÉ 
The MDGs succeeded in generating consensus on and mobilising resources towards agreed goals. They were less successful at clarifying responsibilities for achieving them. The MDG target on sharing global health innovation is particularly ambiguous about the allocation of responsibilities.The members of the consortium behind this proposal assume that the new goals for global health will need to be b ...
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 14

 TERMINÉ 

European and South African HIV co-infection research consortium (ESAHIVCOINFRES)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

The overall aim of the proposed staff exchange program is to establish a long lasting collaboration between South African and European research teams involved in HIV co-infection research. This effort ultimately should lead to new ways to improve the care/treatment for patients with HIV co-infections and to decrease the high mortality among persons with HIV infection in Africa.South Africa is the ...
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 5

 TERMINÉ 
Humans and animals living in poor communities in the developing world often suffer from health problems arising from neglected zoonoses. Control options for these diseases are perceived as either too expensive or to be beyond the mandate of either the human or animal health systems. There is evidence that zoonoses in humans can be suppressed or even eliminated through interventions in animals. Mor ...
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 9

 TERMINÉ 

Combined Highly Active Anti-retroviral Microbicides (CHAARM)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,

This proposal is for a large scale collaborative project in which we propose both to develop novel microbicides directed against new intracellular targets and to investigate novel combinations of highly active anti-retroviral drugs which may be particularly effective as microbicides. Combinations may enhance efficacy but equally importantly will increase the genetic barrier to the development of r ...
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 34

 TERMINÉ 

"Harmonizing, Integrating and Vitalizing European Research on hiv/Aids" (HIVERA)

Date du début: 1 mai 2010, Date de fin: 30 avr. 2015,

"HIV infection is a major worldwide epidemic threatening public health in all affected countries. Although a wide range of financial support has been successfully dedicated to HIV through national and/or EC-funded programmes, there is still little cooperation between national funding programmes in Europe, while this field is highly international, operationally as well as competitively, in all disc ...
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 16

 TERMINÉ 

ADVANZ - Advocacy for the fight against Neglected Zoonotic Diseases (ADVANZ)

Date du début: 1 oct. 2012, Date de fin: 31 mars 2015,

"The aim of ADVANZ (Advocacy for Neglected Zoonotic Diseases) is to persuade decision makers and empower stakeholders at local, regional, and international levels towards a coordinated fight against neglected zoonotic diseases (NZD), first and foremost in Africa, where the burden from NZD are heaviest. If the battle against NZD is going to be won, a major part of the initiative must come through a ...
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 6

 TERMINÉ 
"This project aims at Improving Human Health and Animal Production in developing countries through Integrated Control of Neglected Zoonoses in animals, based on Scientific Innovation and Public Engagement. Neglected zoonoses, such as anthrax, rabies, brucellosis, bovine TB, zoonotic trypanosomiasis, echinococcosis, cysticercosis and leishmaniasis, are major causes of ill-health in developing coun ...
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 23

 TERMINÉ 
Recent health financing reforms in low and middle income countries aim to introduce affordable prepayment and subsidies for low socio-economic groups. However, while such reforms have led to increased utilization of care, often the poor and informal sector continue to be excluded from coverage.Health Inc. puts forward the hypothesis that social exclusion is an important cause of the limited succes ...
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 6

 TERMINÉ 

European Research Infrastructure on Highly Pathogenic Agents (ERINHA)

Date du début: 1 nov. 2010, Date de fin: 31 août 2014,

In the context of the emerging and re-emerging infectious diseases involving highly pathogenic microorganisms, European countries have to be well-prepared to face such threats. However, the Biosafety Level 4 (BSL4) capacity in Europe is not sufficient enough to cover the efficient development of diagnosis, prophylactic and therapeutics means against these pathogens. Moreover, there is no global co ...
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 27

 TERMINÉ 
"Topic: AFRICA BUILD aims to improve capacity for health research and education in Africa, through Information Technologies (IT). It will provide innovative learning and research opportunities.Background: The EU has supported many IT and health initiatives, with significant results. In contrast, there has been no significant transfer of expertise, methods and tools to neighbour countries in Africa ...
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 8

 TERMINÉ 
"This proposal will establish an integrated and synergistic network to address the challenge of multiple drug resistant tuberculosis (MDR-TB) facing the EU. The objective will be attained through the establishment of a European consortium of expert partners with extensive experience in the conduct of basic and clinical research relating to MDR-TB, TB control and epidemiology. This Consortium will ...
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 32

 TERMINÉ 
There is a growing consensus that maternal health outcomes can only be improved through policies and programmes that combine interventions to address the different causes of ill health and target multiple groups. Such policies and programmes are complex in nature as they involve coordination between different tiers in the health system and multiple actors including communities, health workers and ...
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 9

 TERMINÉ 

Health Equity and Financial Protection in Asia (HEFPA)

Date du début: 1 juin 2009, Date de fin: 30 nov. 2013,

In much of Asia, households are liable for large out-of-pocket payments when they use health services. As a result, many fail to seek care or get inadequate care, while others seek care but end up in financial difficulty. Expanding insurance is one obvious policy solution, but private and community-based insurance schemes have rarely been successful, and social insurance schemes have struggled wit ...
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 10

 TERMINÉ 
The research focuses on different types of integrated health care networks (IHN), widely promoted in Latin America in spite of lack of knowledge on their impact. It will look at their impact on equity and efficiency, and its implication for an universal and equitable access to maternal and child care. Research general objective is to provide evidence on the impact of different types of integrated ...
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 4

 TERMINÉ 
"This project aims to assess specific P. falciparum genetic markers for resistance to artemisinin-based combinations (ACT), and to develop innovative, rapid and simple diagnostics for malaria and these markers. Specific objectives are: • To develop and evaluate in disease endemic countries accurate low-tech molecular diagnostic tests. • To identify alleles of candidate resistance genes associated ...
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 8

 TERMINÉ 
Buruli ulcer disease (BUD), caused by Mycobacterium ulcerans, is a neglected bacterial infection of the poor in remote rural areas, mostly affecting children. BUD, the third most common mycobacterial disease in immunocompetent humans after tuberculosis and leprosy, is most endemic in West Africa, but cases have been reported from more than 30 countries. BUD is a mutilating disease leading to sever ...
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 16

 TERMINÉ 
"Visceral leishmaniasis (VL), one of the most-neglected infectious diseases, has an annual incidence of 500,000 cases. Early treatment is a major pillar of the current program for VL elimination on the Indian sub-continent. However, the arsenal of available drugs is very limited, and their use is jeopardized by drug resistance. Combination regimens for VL are under clinical development, but it wil ...
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 10

 TERMINÉ 

Comparative epidemiology of genetic lineages of Trypanosoma cruzi (ChagasEpiNet)

Date du début: 1 janv. 2009, Date de fin: 31 déc. 2012,

The focus of this multidisciplinary proposal is to elucidate the epidemiology of the genetic lineages of T. cruzi, for improved understanding and prevention of Chagas disease. The project will unite skills in genotyping, genomics, genetics and pathogenesis in Europe with considerable compatible skills in South America, and with key research in endemic areas that have distinct characteristics. The ...
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 15

 TERMINÉ 

Novel strategies for the prevention and control of persistent infections (NOPERSIST)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2012,

"Persistent infections such as HIV, tuberculosis´(TB) in humans and para-tuberculosis (ParaTB)-, mycoplasma- and Haemophilus-infections in farm animals are global health problems of immense social and economic importance . HIV-1 affects about 40 million people and M. tuberculosis infection is even higher world-wide. Co-infection with M. tuberculosis is estimated in about one-third of HIV-1 infecte ...
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 12

 TERMINÉ 

Sustainable Nutrition Research for Africa in the Years to come (Sunray)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2012,

This is a critical time for nutrition. Malnutrition rates remain high, particularly in sub-Saharan Africa where only nine out of 46 countries are on track to achieve the first Millennium Development Goal target of a 50% reduction in underweight prevalence among children under five years. Despite the huge cost of malnutrition, investment in the nutrition sector has been insufficient. There has been ...
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 10

 TERMINÉ 

"Health system stewardship and regulation in Vietnam, India and China" (HESVIC)

Date du début: 1 juil. 2009, Date de fin: 31 déc. 2012,

"The proposed project aims to investigate stewardship and regulation as it relates to governance of health systems in policy and practice. It aims to do so by developing an integrated approach to improved stewardship and regulation in health services in Vietnam, India and China, in order to support policy decisions in the application and extension of principles of accessibility, affordability, equ ...
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 6

 TERMINÉ 
"The elicitation of broadly neutralising antibodies (Nab) remains the primary and most challenging goal in HIV-1 vaccine development. Although a few anti-HIV-1 monoclonal antibodies with broadly neutralising capability have been isolated from infected individuals, none of the immunization strategies thus far explored has proven effective in inducing similar antibodies. Objective of this applicatio ...
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 18

 TERMINÉ 
Tuberculosis (TB) continues being a leading cause of death due to a single infectious disease agent. The HIV/AIDS pandemic and the emergence of drug resistance are compounding factors that hinder the control of the disease. Associated with this problem is the emergence of multidrug-resistant (MDR) strains of Mycobacterium tuberculosis, defined as strains resistant to at least isoniazid and rifampi ...
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 8

 TERMINÉ 

European network for global cooperation in the field of AIDS & TB (EUCO-Net)

Date du début: 1 nov. 2008, Date de fin: 30 avr. 2010,

Background Tuberculosis and HIV/AIDS are on the rise worldwide, representing a global public health problem with considerable mutual interaction: TB is the leading cause of mortality for people living with HIV/AIDS, and HIV is the most potent force driving the TB epidemic in countries with a high prevalence of HIV . Especially in rural areas of Africa, Latin America, India and Russia both diseases ...
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 14