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 TERMINÉ 
Ewing Sarcomas (ES) are fatal, rare bone cancers particularly affecting young people. About 60% of patients achieve long term survival with current treatment but there has been no improvement in this proportion for 25 years. Treatment is unsuccessful because chemotherapy fails to prevent the development of, or to effectively treat established, metastases. In addition, of the 600 new cases of ES o ...
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 21

 TERMINÉ 

Personalised Prognostic Tools for Early Psychosis Management (PRONIA)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

Affective and non-affective psychoses have a major negative impact on human society. They account for 6.3% of the global burden of disease and cost €207 billion per year in Europe alone, making them the most expensive brain-related disorders and even more expensive than cardiovascular diseases. This socioeconomic burden is largely caused by two core disease features: onset in adolescence and early ...
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 13

 TERMINÉ 
"SOLUTIONS will deliver a conceptual framework for the evidence-based development of environmental and water policies. This will integrate innovative chemical and effect-based monitoring tools with a full set of exposure, effect and risk models and assessment options. Uniquely, SOLUTIONS taps (i) expertise of leading European scientists of major FP6/FP7 projects on chemicals in the water cycle, (i ...
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 41

 TERMINÉ 

Identification of Novel Targeted Therapies for Renal Cancer (ONCOTREAT)

Date du début: 1 sept. 2013, Date de fin: 31 août 2018,

"Overall, kidney cancers are the eighth most common cancer and the incidence of the most common form (renal cell carcinoma, RCC) has been increasing steadily over the past 30 years. If detected early, surgical removal of RCC can be curative but the prognosis for metastatic disease is very poor. RCC is resistant to conventional therapy and recently introduced targeted therapies form the mainstay of ...
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 2

 TERMINÉ 

Cancer Vaccine development for Hepatocellular Carcinoma (HepaVac)

Date du début: 1 sept. 2013, Date de fin: 31 août 2018,

"Hepatocellular carcinoma (HCC) is the most common primary liver cancer and accounts for about 6% of all new cancer cases worldwide. Given the lack of available effective treatments, the overall prognosis for HCC patients is poor, with a dismal 5-year survival of 5-6%. The main goal of this proposal is to develop a therapeutic cancer vaccine aiming at improving clinical outcome in early-stage HCC ...
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 10

 TERMINÉ 
Information integration is critical for the brain to interact effectively with our multisensory environment. Defining the limits and prerequisites of information integration is fundamental for understanding the mechanisms of normal brain functioning and their disintegration in diseases such as neglect & vegetative state. A key question is to what extent multisensory integration (MSI) is automatic ...
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 1

 TERMINÉ 
Conduct Disorder (CD) and Oppositional Defiant Disorder with symptoms of Conduct Disorder (which is included among the abbreviation “CD” throughout the proposal) has a highly negative impact for the affected individual as well as for families and society. Although the number of females exhibiting serious aggressive behaviours is growing, the majority of studies on aetiology and treatment of CD hav ...
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 19

 TERMINÉ 

Gravitational Wave Initial Training Network (GRAWITON)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

The GraWIToN project aims to train 13 ESRs in the gravitational wave search field. This research field is in an impressive expansion period, thank to a new generation of detector under installation in these years, to the promise of the exciting discovery in 5 years from now of this kind of signal, predicted in the General Relativity of Einstein, to the enlarging of the world wide scientific comm ...
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 10

 TERMINÉ 

Addressing Fundamental Challenges in the Design of new generation fuels (GENFUEL)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

There is a pressing need at the European and global levels to address challenges in the design of a new generation of fuels in order to achieve significant efficiency and emissions benefits in modern downsized boosted engines employing gasoline and ethanol blends. Abnormal combustion phenomena are a severe constraint to the use of much higher boosting pressures which are needed for significant ga ...
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 8

 TERMINÉ 
We propose a PhD programme for 4 Early-Stage Researchers (ESR) in tuberculosis (TB) drug discovery. Often associated with poverty, TB is rampant in many parts of Africa and Asia but has now also returned to developed nations. Growing resistance against currently used antibiotics is one of the most pressing problems of the global TB epidemic. Treating TB infections requires a drug cocktail given fo ...
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 2

 TERMINÉ 

MEsenchymal stem cells to Reduce Liver INflammation (MERLIN)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

"Prevalence of liver disease is c6% (29 million people) in the EU with mortality rates from chronic liver diseases estimated at 14.3 per 100.000 in the EU-25 in 2004. Most liver diseases have a significant inflammatory component that underpins liver damage and fibrogenesis, yet current therapies have limited effectiveness. Safe novel anti-inflammatory therapies would satisfy a large unmet need for ...
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 9

 TERMINÉ 

New Generation Solid Oxide Fuel Cells (NewGenSOFC)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

This project combines sector-leading partners from clean energy projects to achieve allied goals. The project fosters cooperation between SOFC technologists, ceramic manufacturers and fuel cell academicians, to establish new ceramic fuel cell manufacturing capability in Europe for sustainable home energy solutions. It will validate the technical, social and commercial prospects of specific fuel ce ...
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 4

 TERMINÉ 

European Identity, Cultural Diversity and Political Change (EUINDEPTH)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

The strategic objective of the whole FP7 is to support research in all areas, including the Science in Society. The major goal of the Seventh Framework Programme for research and Technological Development is to keep the EU as a world leader. The European identity, cultural diversity and political changes could be the key issue in the encouragement of societal dialog on research policy, stimulating ...
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 8

 TERMINÉ 
"The main S&T objective of CATSENSE is to design novel high performance catalysts and biosensors by a new interactive approach combining i. the production of mono and bi-metallic gas-phase clusters of controlled homogeneity, ii. the extensive characterisation of their morphology, structure (ex and in situ) and optical properties, iii. theoretical modelling and screening, and iv. catalytic and bios ...
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 7

 TERMINÉ 
... n the role of DNA methylation in distal regulatory elements (DREs). Based on recent genome-wide studies, we hypothesize that DREs are more sensitive than CGIs to changes in DNA methylation, thus they may function as primary responders to epigenetic therapies. We previously showed DREs are indeed epigenetically dynamic and prone to demethylation, the process that may involve a newly identified DNA ...
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 1

 TERMINÉ 

Materials’ Innovations for a Safe and Sustainable nuclear in Europe (MATISSE)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

The European Energy Research Alliance, set-up under the European Strategic Energy Technology Plan, has launched an initiative for a Joint Programme on Nuclear Materials (JPNM). The JPNM aims at establishing key priorities in the area of advanced nuclear materials, identifying funding opportunities and harmonizing this scientific & technical domain at the European level by maximizing complementarit ...
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 32

 TERMINÉ 
"INTERFACES is a supra-disciplinary training and research network that aims (1) to develop conceptual process understanding of the role of ecohydrological interfaces (i.e. system boundaries) for the transport and transformation of fluxes of heat, energy and water and interlinked biogeochemical cycles (C, N, O) at micro- to landscape-scale; and (2) to create the next generation of supra-disciplinar ...
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 13

 TERMINÉ 

Pathogen COinfection: HIV, Tuberculosis, Malaria and Hepatitis C virus (PathCO)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,

Acquired immune deficiency (AIDS), tuberculosis (TB) and malaria are the primary infectious diseases causing death world wide. In addition to these pathogens, 170 million people are infected with hepatitis C virus (HCV), which leads to chronic liver disease. Because of shared routes of transmission, HCV co-infection is recognized as a major cause of morbidity and mortality among HIV-1 infected per ...
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 11

 TERMINÉ 
Nanotechnology is a key enabling technology. Still existing uncertainties concerning EHS need to be addressed to explore the full potential of this new technology. One challenge consists in the development of methods that reliably identify, characterize and quantify nanomaterials (NM) both as substance and in various products and matrices. The European Commission has recently recommended a definit ...
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 30

 TERMINÉ 

Control of meiotic recombination: from Arabidopsis to crops (COMREC)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

"Global population stands at 7 billion and is predicted to reach 9 billion by 2050. It is anticipated that food production will need to increase by at least 50% to meet the demand arising from this increase in population. This will require a sustained improvement in crop yield. The nature of this challenge is exacerbated by the likely impact of climate change. These factors combine to make Food Se ...
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 12

 TERMINÉ 
... ill be investigated, allowing low or no impact on train operations.The fragility of some key component of the infrastructure system (especially in extreme weather conditions) such as switches may impact the efficiency of the whole system. The resilience of switches to any kind of known failure will be reinforced, as well as the ability of the operation system to recover from incidents.Capacity enh ...
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 48

 TERMINÉ 
... industrial companies, and 2 Associated Partners from Japanese Universities form a network of complementary scientific and techno-economical expertise.Novel borohydride- and nitride based materials may allow for high energy storage densities in terms of both hydrogen and electrochemical processes. For commercial introduction, a prerequisite is the cost efficient large scale production from abundan ...
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 13

 TERMINÉ 

FUTURE ATOMIC CLOCK TECHNOLOGY (FACT)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

During the last decades atomic clocks and frequency standards have become an important resource for advanced economies with impact ranging from satellite navigation (GPS, GLONASS, Galileo) to high speed communication networks, where they ensure synchronisation of data packets at ever higher bit rates. In this field the wake of the new millennium has been marked by the invention of frequency comb t ...
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 15

 TERMINÉ 
... nces in technology led by the private sector. ELUTE's main research goal is to further understanding of the environmental fate and behaviour of brominated persistent organic chemicals and how best we may deploy recent advances in analytical instrumentation to do so. Our vision is that enhanced understanding of the underpinning science will benefit public health and associated regulators and scient ...
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 2

 TERMINÉ 
KnowHY aims to provide the FC&H2 sector with a training offer for technicians and workers featuring quality in contents, accessibility in format and language, practicality for the targeted audience, ease of scalability and update, and at competitive costs which make the training offer economically sustainable after project completion. Thanks to this project both OEMs as well as professionals can r ...
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 13

 TERMINÉ 

Vascular antibody-mediated pharmaceutically induced tumour resection (VAMPIRE)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

"The most significant advance in cancer therapeutics in recent years has been the introduction of monoclonal antibodies into widespread clinical usage. A consequence of this rapid emergence of antibodies as therapeutics is a lack of trained scientists within the EU with the requisite skills to enable antibody development at a globally competitive pace. The University of Birmingham (UoB) together w ...
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 2

 TERMINÉ 

European Rare Earth Magnet Recycling Network (EREAN)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

"Because China dominates the rare-earth market and is reducing its export quota, there is a very high supply risk for rare earths in Europe. To tackle this rare-earth crisis, Europe needs to invest in primary mining, substitution and, in particular, urban mining/recycling. To date, less than 1% of the rare earths are being recycled, due to, amongst others, a lack of efficient recycling technologie ...
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 9

 TERMINÉ 
Primary biliary cirrhosis (PBC) is the most prevalent of adult autoimmune liver diseases, seen in both genders and all ethnicities, but remains without rational treatment. Its immune mediated liver injury is driven by interacting innate, humoral and cellular pathways, on a strong background of genetic and environmental risk. Improved treatment is a priority for patients but is hindered by a) compl ...
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 1

 TERMINÉ 

Steel Coatings For Reducing Degradation in SOFC (SCORED 2:0)

Date du début: 1 juil. 2013, Date de fin: 30 juin 2017,

The economic viability and market place entry of SOFC power systems is directly dependent on their longevity and production costs. Adequate operational life spans can only be achieved, if the performance degradation of the SOFC stacks and Balance of Plant components over time can be considerably reduced. At the same time, manufacturing costs have to be lowered dramatically for the specifically nec ...
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 9

 TERMINÉ 
The overarching goal of AMAZE is to rapidly produce large defect-free additively-manufactured (AM) metallic components up to 2 metres in size, ideally with close to zero waste, for use in the following high-tech sectors namely: aeronautics, space, automotive, nuclear fusion and tooling.Four pilot-scale industrial AM factories will be established and enhanced, thereby giving EU manufacturers and en ...
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 29

 TERMINÉ 
The main aim of this project is to establish, maintain and make sustainable a world class research group with a focus on (foreign and domestic) development policies in post-socialist spaces. Thanks to its wide geographical and disciplinary focus, this IRSES will provide an international and intercultural environment for a team of researchers to connect, reflect, come up with new findings and estab ...
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 4

 TERMINÉ 
Description STRANDS aims to enable a robot to achieve robust and intelligent behaviour in human environments through exploitation of long-term experience. The approach is based on understanding 3D space and how it changes over time, from milliseconds to months. The project will develop control mechanisms which yield adaptive behaviour in hig ...
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 8

 TERMINÉ 

European Multicentre Tics in Children Studies (EMTICS)

Date du début: 1 déc. 2011, Date de fin: 31 mai 2017,

This project will undertake pre-clinical and cohort studies that address susceptibility factors for paediatric and adolescent tic disorders, with a particular focus on comorbid obsessive-compulsive symptomatology, from clinical, epidemiological, genetic, microbiological and immunological angles. EMTICS aims to elucidate the complex aetiology of the onset and clinical course of chronic tic disorder ...
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 33

 TERMINÉ 

Virtual Prototyping of Tactile Displays (PROTOTOUCH)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,

"It is estimated that touch screen module revenues will reach $23.9 billion by 2017. These user interfaces have become one of the most common input devices for digital media, e.g. in mobile phones and computers. Current devices incorporate relatively primitive vibrotactile haptic-feedback. The aim of PROTOTOUCH is to develop tactile displays with high fidelity haptic recognition, so that buttons w ...
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 10

 TERMINÉ 
"Extensive clinical and epidemiological data clearly shows that chronic periodontal disease (PD), the most prevalent infectious inflammatory disease of mankind, is strongly linked to systemic inflammatory diseases such as cardiovascular diseases (CVD) , rheumatoid arthritis (RA) , and chronic obstructive pulmonary disease (COPD) . Taking into account that up to 30% of the adult population worldwid ...
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 11

 TERMINÉ 
Disorders of sex development (DSD) are a conglomerate of rare diseases with an estimated incidence of 1: 4500. The causes of DSD are mainly disorders with gonadal dysgenesis, decreased androgen synthesis or function in XY males or disorders with elevated androgen production in XX females. Decision on sex of rearing is difficult in some cases as the prenatal androgen imbalances result in ambiguous ...
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 17

 TERMINÉ 
The aim of the project is to develop a completely new manufacturing system for the volume production of miniaturised components by overcoming the challenges on the manufacturing with a wide range of materials (metallic alloys, composites, ceramics and polymers), through: (i) developing a high-throughput, flexible and cost-efficient process by simultaneous electrical-forming and electric-fast-sinte ...
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 17

 TERMINÉ 

Decision-making within cells and differentiation entity therapies (DECIDE)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

"Our ITN has both scientific and therapeutic targets. Research in Work Package 1 (WP1) aims to advance understanding of normal blood cell development and why primitive cells fail to differentiate in acute myeloid leukaemia (AML). Research in WP2 will use the information gained from WP1 to develop ways of alleviating the differentiation block in AML and so deliver new agents for use in differentiat ...
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 8

 TERMINÉ 
The NanoMILE project is conceived and led by an international elite of scientists from the EU and US with the aim to establish a fundamental understanding of the mechanisms of nanomaterial interactions with living systems and the environment, and uniquely to do so across the entire life cycle of nanomaterials and in a wide range of target species. Identification of critical properties (physico-che ...
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 30

 TERMINÉ 

A Guided Matter-Wave Interferometer on a Atom-Chip (MatterWave)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,

The ultimate aim of the proposed research is to make ultra-sensitive matter-interferometry available in a compact and eventually portable device. Specifically, we seek to test the ideas in a guided matter-wave interferometer based on ultracold bosonic atoms. We will explore matter-wave interferometry in macroscopic traps as well as on atom-chips. Such device has the potential to induce a step chan ...
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 5