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 TERMINÉ 
The problem: finding the right patient for the right treatmentDespite a large and growing disease burden in osteoarthritis (OA), many pharmaceutical companies have de-emphasized or even abandoned OA drug development due to perceived hurdles. Crucial in this is the lack of appropriate outcome measures that can robustly identify patient benefit from a specific therapy. The lack of specific and sensi ...
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 25

 TERMINÉ 
ULTRA-DD (Unrestricted Leveraging of Targets for Research Advancement and Drug Discovery) will be an European-wide, highly collaborative and inclusive consortium, to validate new targets for drug discovery by (1) generating high quality research tools, with an emphasis on chemical probes; (2) generating the chemical probes in the most cost-effective manner, using structure-guided methods and harne ...
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 10

 TERMINÉ 

Next Generation Driving Behaviour Models (NG-DBM)

Date du début: 1 févr. 2015, Date de fin: 31 janv. 2019,

"Microscopic traffic simulation tools which replicate individual driver decisions and combine them to deduce network conditions are popular tools for evaluating transport planning and management options. An essential component of such tools is a set of mathematical models of driver behaviour, including but not limited to longitudinal movement models, lateral movement models, and route choice model ...
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 1

 TERMINÉ 

Dynamics-aerosol-chemistry-cloud interactions in West Africa (DACCIWA)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2018,

"Massive economic and population growth and urbanisation are expected to lead to a tripling of anthropogenic emissions in southern West Africa (SWA) between 2000 and 2030, the impacts of which on human health, ecosystems, food security and the regional climate are largely unknown. An assessment of these impacts is complicated by (a) a superposition with effects of global climate change, (b) the st ...
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 17

 TERMINÉ 
StratoClim will produce more reliable projections of climate change and stratospheric ozone by a better understanding and improved representation of key processes in the Upper Troposphere and Stratosphere (UTS). This will be achieved by an integrated approach bridging observations from dedicated field activities, process modelling on all scales, and global modelling with a suite of chemistry clima ...
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 30

 TERMINÉ 
Although there is a large body of knowledge available on soil threats in Europe, this knowledge is fragmented and incomplete, in particular regarding the complexity and functioning of soil systems and their interaction with human activities. The main aim of RECARE is to develop effective prevention, remediation and restoration measures using an innovative trans-disciplinary approach, actively inte ...
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 30

 TERMINÉ 
Ewing Sarcomas (ES) are fatal, rare bone cancers particularly affecting young people. About 60% of patients achieve long term survival with current treatment but there has been no improvement in this proportion for 25 years. Treatment is unsuccessful because chemotherapy fails to prevent the development of, or to effectively treat established, metastases. In addition, of the 600 new cases of ES o ...
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 21

 TERMINÉ 

Emotional attributions of climate change (EACC)

Date du début: 1 avr. 2014, Date de fin: 31 mars 2018,

"It is now clear that managers, and their organisations, are under increasing pressure to respond to environmental issues, and to climate change in particular. Research has identified the important role that individuals play in affecting organisational change, yet more remains to be done. Despite past success of cognitive and behavioural perspectives in explaining proenvironmental behaviours, few ...
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 1

 TERMINÉ 
The DROPSA consortium will create new knowledge and understanding of the damage and losses of fruit crops resulting from pests and pathogens, with a specific focus on the new and emerging threats due to Drosophila suzukii and quarantine pathogens Pseudomonas syringae, Xanthomonas fragariae and X. arboricola. The project will deliver a cost effective approach that can be widely implemented by the E ...
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 27

 TERMINÉ 
"Since anthropogenic CO2 is the most important long-lived greenhouse gas causing climate change, improved understanding on how it cycles between the active land, ocean, and atmospheric reservoirs is a main concern for humanity. During the past decade, annual fossil fuel CO2 emissions have sharply increased at a rate of 3%/yr, almost doubling the rate of the prior three decades. To a big surprise, ...
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 1

 TERMINÉ 
"The applicant, Prof Regina Lee Blaszczyk, is the Leadership Chair in the History of Business and Society in the School of History at the University of Leeds. The aim of this CIG is to help Blaszczyk, who moved to Europe in Feb 2013, to integrate her specialized expertise in the cultural history of business into the University of Leeds, the UK, and the EU. The research is built around a historica ...
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 1

 TERMINÉ 

SURFS-UP: Freak Waves and Breaking Wave Impact on Offshore Structures (SurfsUp)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

Wave breaking and wave impact on maritime structures are difficult to model mathematically and numerically. The challenge is that nonlinear and breaking waves with their dynamic air-water interface need to be modelled accurately, including interactions with structures. We aim to progress nonlinear and breaking wave interactions on offshore wind turbines in two ways.Firstly, nonlinear unbroken wave ...
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 2

 TERMINÉ 
Scientific understanding of the role and mechanisms of bioactives is fragmented. Research often addresses the theoretical possibility of health improvement effects rather than their real, practical use for everyday diets. Bioactives cannot be considered as discrete chemical compounds and research must focus on bioactive-enriched foods (BEF), if consumer demands for foods delivering appropriate hea ...
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 28

 TERMINÉ 

European Facility for Airborne Research in Environmental and Geo-sciences (EUFAR2)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

EUFAR aims at providing researchers with Open Access to the airborne facilities the most suited to their needs. EUFAR thus allocates Transnational Access to 21 installations, develops a culture of co-operation between scientists and operators, and organizes training courses to attract young scientists to airborne research. To improve the quality of the service, EUFAR supports the experts on airbor ...
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 24

 TERMINÉ 

Correctness by Construction (CORCON)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

"As software becomes ever more ubiquitous in our lives, the need to ensure it runs without error becomes ever more important. Restarting a phone is a simple, if inconvenient task; restarting an aeroplane in mid-flight is not an option!Correct by construction programming offers a revolutionary approach to program verification where programs can contain not just computations as is normal, but also ...
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 9

 TERMINÉ 

European Clinical Research Infrastructures Network - Integrating Activity (ECRIN-IA)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,

ECRIN is a distributed ESFRI-roadmap pan-European infrastructure designed to support multinational clinical research, making Europe a single area for clinical studies, taking advantage of its population size to access patients. Servicing multinational trials started during its preparatory phase, and it now applies for an ERIC status by 2011. The ERIC budget will be restricted to core activities re ...
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 48

 TERMINÉ 

European Lead Factory (EUC²LID)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provi ...
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 34

 TERMINÉ 

The Ecology and Evolution of Mimicry in a Changing World (EcoEvoMimic)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

Climate change is influencing the spatio-temporal distributions of a wide range of taxa. Where interacting species exhibit divergent climate-induced variation presence or abundance, the interactions between those species will also be affected. This research proposal will consider, for the first time, the effects of climate change on a mimicry system involving Hymenoptera and Syrphidae (Diptera). ...
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 1

 TERMINÉ 

Ultra-fast Laser Surfacing of Teeth for Resistance to Erosion (LUSTRE)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

"The “LUSTRE-IAPP” has emerged from a background of successful bilateral academic and industrial collaborations within the UK and Italian partners, in which the knowledge transfer and training of ERs and ESRs are centred on four key aspects of academic research leading to KT and commercialisation activities. These are in the areas of: a) in the engineering and fabrication of laser glass hosts for ...
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 8

 TERMINÉ 
Clouds are a very important, yet not well understood feedback factor in climate change and they contribute to the effective radiative forcing (ERF) from aerosol-cloud interactions (ACI). The uncertainty in ERFaci is larger than for any other forcing agent. Also, feedbacks between the terrestrial and marine biosphere and the atmosphere involving ACI are thought to play an important role in regulati ...
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 22

 TERMINÉ 

THE PROBABILISTIC CONSTRUAL OF MODALITY (PCM)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"The project concerns the semantics of modal expressions in language, and in particular modal verbs such as 'might', 'must' and 'can'. The hypothesis under investigation is the Probabilistic Construal of Modality, stating that modal verbs like the above should be given a semantic analysis in terms of (among other things) probability functions. This is a very active topic of research within philoso ...
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 1

 TERMINÉ 
"Supramolecular polymeric assemblies represent an emerging, promising class of systems with superior versatility compared to their covalent polymeric counterparts. They offer exciting new opportunities for stimuli-responsive structures exhibiting reversible tunable properties, with applications in foodstuff, coatings , cost-efficient processes or biomedical areas. To explore their potential and de ...
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 11

 TERMINÉ 
The present research focuses on achieving a deeper understanding of how European entrepreneurs can speed up the internationalisation process and, therefore, improve the performance of their (often resource constrained) SMEs.From the field experience and recent international entrepreneurship literature, it emerges that often entrepreneurs adopt “unexpected” lines of reasoning and adapt to changing ...
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 1

 TERMINÉ 
"Across the life span, people face decisions about their health, finances and well-being. People of all ages therefore need good decision-making competence, referring to the ability to avoid decision biases and to obtain desired life outcomes. Reviews suggest that relatively little is known about how decision-making competence changes with age. However, well-documented aging-related declines in fl ...
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 1

 TERMINÉ 

Controlling domain wall dynamics for functional devices (WALL)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

"WALL is a training network on the topic of domain walls in nanoscale magnetic structures, which will provide the next generation of researchers in this area of advanced technology. Domain walls (DWs) are the interfaces separating magnetic domains, their high speed manipulation in nanostructures will lead to the next generation of new and low power functional devices for computation and communicat ...
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 8

 TERMINÉ 

Enhanced Research Activities in Stratigraphy (ERAS)

Date du début: 1 nov. 2011, Date de fin: 20 août 2017,

Robust stratigraphic correlations are essential in deciphering Earth History, yet there are crucial gaps and limitations in the current status of Cenozoic planktonic foraminiferal biochronology. Previous records are hampered by low resolution analysis, incomplete cores and/or lack of magnetostratigraphic age control. As such there is a critical need for high resolution biochronology to improve the ...
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 2

 TERMINÉ 

Scalable Switching Architectures for Next-Generation Data Center Networks (SCALE)

Date du début: 1 août 2013, Date de fin: 31 juil. 2017,

"The growing trend in cloud computing is rising the need for building massive data centers capable of holding hundreds to thousands of servers that sustain and support a variety of services (e.g, web-serach, video content hosting and distribution, social networking and large-scale computations). The interconnection network infrastructure of the data center is key to its cost, performance and feasi ...
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 1

 TERMINÉ 
The aim of CASCADE is to obtain a better understanding of sudden ecosystem shifts that may lead to major losses in biodiversity and ecosystem services, and to define measures that can be used to prevent such shifts. The focus of CASCADE is explicitly on drylands as being one of the most fragile and threatened ecosystems in Europe. CASCADE will investigate the historical evolution of dryland ecosys ...
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 15

 TERMINÉ 

Automated Driving Applications and Technologies for Intelligent Vehicles (AdaptIVe)

Date du début: 1 janv. 2014, Date de fin: 30 juin 2017,

AdaptIVe will enhance the performance and improve the acceptance of automated driving of cars and trucks. The project develops new and integrated automated functions to improve traffic safety by minimizing the effects of human errors and to enhance traffic efficiency by smoother flows and reduced congestion.The approach is based on a shared control concept, assuring proper collaboration between th ...
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 32

 TERMINÉ 
Modern lifestyle has dramatically changed the daily rhythms of life. Physical activity, diet and light exposure are no longer restricted to daytime hours, as technical and economical de-mands fuel the necessity to work outside usual working hours. Recent studies show that al-tered light exposure, shifted exercise patterns and untimely food intake following extended active periods into the night di ...
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 17

 TERMINÉ 
Road transport is indispensable for the exchange of goods and persons, but at the same time has severe negative consequences, among others related to road safety and environment. In order to meet EU targets, both the number of road crashes and vehicle emission levels need to be reduced substantially. For identifying the next generation of measures that will enable us to actually reach these target ...
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 21

 TERMINÉ 
Description STRANDS aims to enable a robot to achieve robust and intelligent behaviour in human environments through exploitation of long-term experience. The approach is based on understanding 3D space and how it changes over time, from milliseconds to months. The project will develop control mechanisms which yield adaptive behaviour in hig ...
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 8

 TERMINÉ 

EU BON: Building the European Biodiversity Observation Network (EU BON)

Date du début: 1 déc. 2012, Date de fin: 31 mai 2017,

Sustainable governance of our biological resources requires reliable scientific knowledge that meets the needs of society. Current biodiversity observation systems and environmental datasets are unbalanced in coverage and not integrated, limiting integrative analyses and implementation of environmental policies.EU BON presents an innovative approach towards integration of biodiversity information ...
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 32

 TERMINÉ 
European Commission plans for wind energy development by 2020, highlights a fully competitive onshore wind power with 20% penetration. One of the better opportunities to fulfil this aim is the integration of small and medium wind turbines into urban and peri-urban environments, due to the potential market given. However, nowadays there are several barriers) that have relegated the Small Wind Turbi ...
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 16

 TERMINÉ 

Quantitative T cell Immunology (QuanTI)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,

The primary objective of this ITN is to train a new generation of European quantitative immunologists, who will be able to address challenges arising in Systems Immunology. This will be achieved with the proposed Network, Quantitative T cell Immunology (QuanTI), that will train 11 ESRs and 4 ERs, bringing together renowned experimental and theoretical scientists from private and academic instituti ...
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 12

 TERMINÉ 
"The main aim of this proposal is to set up an Indo-European Research Network in Mathematics for Health and Disease, INDOEUROPEAN-MATHDS, that will allow the transfer of knowledge, research and training between partners. The Network will involve physicists, mathematicians, statisticians, probabilists, biologists, immunologists and engineers. The Network will create new collaborations and reinfor ...
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 7

 TERMINÉ 

Worker participation and job preservation in recessionary conditions (WPART2013)

Date du début: 20 avr. 2015, Date de fin: 19 avr. 2017,

"The proposed research will be conducted by Dr. Gabriel Burdín (the applicant) who obtained his PhD at the University of Siena (Italy) while developing a successful early research career focused on the economics of worker-managed firms. He will be hosted by the centre for Economics Research on Governance and Organization (ERGO) at Leeds University Business School (UK). The scientist in charge is ...
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 1

 TERMINÉ 
"FUTURE-BET addresses tribocorrosion of bearing systems. BET will address bearing design and performance to alleviate the effects of tribocorrosion in industrial sectors which have a great impact on the EU economy; namely (a) offshore wind power, (b) automotive, (c) offshore oil and gas, (d) new renewable energy technologies, (d) paper manufacturing and (e) hydropower. Each of the aforementioned a ...
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 2

 TERMINÉ 
"FLUTCORE will develop a novel universal influenza A virus (IAV) vaccine based on the tandem core vaccine platform. Recent influenza pandemics have emphasized the urgent need for better vaccines that are reactive with multiple IAV subtypes and that are no longer dependent on intimate knowledge of the prevalent virus. We propose to replace the existing seasonal IAV vaccine with a virus like particl ...
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 7

 TERMINÉ 
"Myocardial structure is important in the triggering and maintenance of many cardiac arrhythmias including atrial and ventricular fibrillation. Detailed knowledge of myocardial structure is essential to the understanding of these disorders and in the development of diagnostic and therapeutic strategies. This must include the normal and pathological distribution of key functional proteins such as c ...
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 4