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 TERMINÉ 
Instruct-Ultra aims to advance the scope and efficiency of implementation of Instruct and consolidate the foundations for long-term sustainability. This will be achieved through specific objectives: expand Instruct membership to new Member States and increase global links; engage new user communities; improve efficiencies in service delivery; improve data capture and management; adjust the scale a ...
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 19

 TERMINÉ 
Screening for vision and hearing disorders in children has shown to be highly effective. EU-directive 16620/11 invites EU-member states to give priority to such screening programmes. Early detection and treatment of a lazy eye (prevalence 3%) prevents lifelong visual impairment. Early detection and treatment of hearing impairment (prevalence 0.15%) prevents delayed speech and language development. ...
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 10

 TERMINÉ 

Readiness of ICOS for Necessities of integrated Global Observations (RINGO)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The proposed project “Readiness of ICOS for Necessities of integrated Global Observations” (RINGO) aims to further development of ICOS RI and ICOS ERIC and foster its sustainability. The challenges are to further develop the readiness of ICOS RI along five principal objectives: 1. Scientific readiness. To support the further consolidation of the observational networks and enhance their quality. Th ...
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 26

 TERMINÉ 

Molecular Tools for Nucleic Acid Manipulation for Biological Intervention (MMBio)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

MMbio will bridge the classically separate disciplines of Chemistry and Biology by assembling leading experts from academia and non-academic partners (industry, technology transfer & science communication) to bring about systems designed to interfere therapeutically with gene expression in living cells. Expertise in nucleic acid synthesis, its molecular recognition and chemical reactivity is combi ...
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 13

 TERMINÉ 

Comorbid Conditions of Attention deficit / hyperactivity disorder (CoCA)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Understanding mechanisms underlying comorbid disorders poses a challenge for developing precision medicine tools. Psychiatric disorders are highly comorbid, and are among the last areas of medicine, where classification is driven by phenomenology rather than pathophysiology. We will study comorbidity between the most frequent psychiatric conditions, ADHD, mood/anxiety, and substance use disorders, ...
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 17

 TERMINÉ 
CHASSY will unlock the full potential of the yeasts Saccharomyces cerevisiae, Yarrowia lipolytica and Kluyveromyces marxianus as cell factories for production of high value compounds which have applications in the cosmetic, nutraceutical and white biotechnology sectors. Current cell factory strains for these classes of product are restricted to proof-of-principle levels because of limited precurso ...
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 10

 TERMINÉ 
The European Pharma industry is a major contributor to EU well-being, both in public health and economic (sales >200 billion €/year) terms. To maintain global leadership, it must respond to challenges from low-cost producers e.g. China by bringing new drug molecules to market in a streamlined, cost-effective manner. This strategy is underscored by recent initiatives of European regulators to exped ...
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 9

 TERMINÉ 
CELTA: Convergence of Electronics and Photonics Technologies for Enabling Terahertz Applications aims to produce the next generation of researchers who will enable Europe to take a leading role in the multidisciplinary area of utilizing Terahertz technology for applications involving components and complete systems for sensing, instrumentation, imaging, spectroscopy, and communications. All these ...
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 13

 TERMINÉ 
In the face of the increasing global consumption of fossil resources, photosynthetic organisms offer an attractive alternative that could meet our rising future needs as clean, renewable, sources of energy and for the production of fine chemicals. Key to the efficient exploitation of these organisms is to optimise the conversion of Solar Energy into Biomass (SE2B). The SE2B network deals with this ...
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 12

 TERMINÉ 

Angular studies of photoelectrons in innovative research environments (ASPIRE)

Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,

In the ASPIRE project, whose academic and industrial beneficiaries are world leading in their complementary fields of expertise, the overarching research goal is the measurement of photoelectron angular distributions (PADs) in the “molecular frame” (MF) of systems of biological relevance. These MF-PADs can be interpreted as electron diffraction patterns, achieved by “illuminating the molecule from ...
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 9

 TERMINÉ 
Self-renew and multilineage potential characterize stem cells. We have recently described that pancreas progenitor cells extracted from adult donors can be expanded long-term in vitro into 3D structures, which we have termed organoids. Pancreas organoids reproduce in vitro all the features of pancreas ductal epithelia, and have a limitless expansion potential. Thus, pancreas organoids promise t ...
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 7

 TERMINÉ 

Privacy and Usabiliy (Privacy.Us)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,

With the rapid accumulation and processing of personal data by numerous organizations, it is of paramount importance to protect people from adverse uses of their data, while allowing them to enjoy the benefits the use of these data can possibly provide. This is the question of protecting citizens’ privacy, while enabling them to make informed decisions regarding their actions with privacy implicat ...
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 10

 TERMINÉ 

Deciphering the Metabolism of Haematological Cancers (HaemMetabolome)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,

It has long been realised that metabolism is central to cellular development, proliferation and homeostasis. Collectively, aberrations in metabolism are now recognised as a major hallmark of cancer, opening new avenues for personalised medicine. As haematological malignancies are multi-factorial diseases, our main emphasis will be on the integration of biomedical multi-omics data and computational ...
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 4

 TERMINÉ 

Endoplasmic Reticulum Stress in Health and Disease (TRAIN-ERS)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,

Endoplasmic reticulum (ER) stress is emerging as a common feature in the pathology of numerous diseases including cancer, neurodegenerative disorders, metabolic syndromes and inflammatory diseases. Thus ER stress represents a potential therapeutic intervention point to be exploited to develop novel therapies, diagnostic tools and markers for these diseases. However, exploitation is hampered by the ...
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 12

 TERMINÉ 

Brain barriers training (BtRAIN)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

The brain barriers function to protect the central nervous system (CNS) from neurotoxic compounds. By the same traits they unfortunately block delivery of drugs to the CNS thus hindering proper diagnosis and effective treatment of neurological disorders including Alzheimer’s disease and multiple sclerosis. The unusual complexity of the brain barriers has severely hampered progress in the market of ...
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 11

 TERMINÉ 

Intra Erythrocyte Dexamethasone in the treatment of Ataxia Telangiectasia (IEDAT)

Date du début: 1 janv. 2016, Date de fin: 30 avr. 2019,

The main objective of the project is to provide a treatment of the neurological symptoms of patients with Ataxia Telangiectasia (AT), a rare progressively disabling and life-shortening genetic disease for which no therapy is currently available. To achieve this, a pivotal Phase III study will be conducted, to allow regulatory filing to obtain market authorization in EU and USA by 2019. EryDex is a ...
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 7

 TERMINÉ 
Most European Lifelong Learning (LLL) policies have been designed to create economic growth and, at the same time, guarantee social inclusion (EC 2010). First, we will study how different LLL policies are compatible with each other in terms of their orientations and objectives and how each policy considers the needs of ‘young adults’. Second, we will research the intended and unintended effects of ...
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 15

 TERMINÉ 
"Data on seawater composition since the start of the Phanerozoic eon ~540 million years ago provide essential information for understanding long-term chemical processes of socio-economic dimension like the evolution of life, land-ocean interaction, atmospheric chemistry, ecosystem adaptation to climate change, oceanic trace metal cycling, and for applied geological processes like the formation of ...
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 14

 TERMINÉ 

EUROPOL

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

NMR and MRI play unique roles in contemporary Science, from Physics, Chemistry and Biology, to clinical research and diagnosis. Despite its irreplaceable role, further progress in NMR and MRI is hampered by sensitivities that are much lower than those of alternatives such as mass-spec, or PET. The prospects of solving this problem by “bigger machines” are uncertain and of poor return, given the hi ...
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 12

 TERMINÉ 
MR-guided Focused Ultrasound Surgery (MRgFUS) combines high intensity focused ultrasound for thermal ablation of diseased tissue with MR imaging to visualise the tumour and surrounding anatomy and to provide MR thermal feedback.However, MRgFUS treatment of the liver and other abdominal organs present tremendous technological challenges, including motion due to breathing and shielding of the target ...
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 11

 TERMINÉ 
Attention deficit/hyperactivity disorder (ADHD) and autism spectrum disorders (ASD) are frequent, chronic and highly heritable neurodevelopmental disorders. Despite their societal importance, progress in understanding disease biology has been slow and no curative treatment options are available.The pan-European training network MiND aims to educate a new generation of researchers in the field of n ...
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 12

 TERMINÉ 

European Digital Online-Game for Intercultural Learning and Translanguaging

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2018,

The increasing number of refugees and migrants within EU countries forces all stakeholders involved in language education and integration to rethink traditional concepts of language education. Successful integration of migrants, especially in participatory processes, strongly depends on learning local foreign languages and intercultural competencies, without neglecting heritage languages and cultu ...
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 6

 TERMINÉ 
Aggression is a basic physiological trait with important roles throughout evolution, both in defence and predation. When expressed in humans in the wrong context, aggression leads to maladjustment, social impairment and crime. Despite this, knowledge about aggression aetiology is limited and current treatment strategies are insufficient. Contingent to a subdivision into impulsive and instrumental ...
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 27

 TERMINÉ 

European University Tandem

Date du début: 1 oct. 2015, Date de fin: 31 mars 2018,

European University Tandem Since the project start on 1 October 2015, all project outputs have been realized largely within the envisaged time frames. Until the end of August 2016, two project meetings took place, the kick-off meeting in Frankfurt (Oct 2015) and the second meeting in Barcelona (March 2016). The third meeting in Florence in coming up in September 2016. The first 6 months, between t ...
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 7

 TERMINÉ 

Human Brain Project Specific Grant Agreement 1 (HBP SGA1)

Date du début: 1 avr. 2016, Date de fin: 31 mars 2018,

Understanding the human brain is one of the greatest scientific challenges of our time. Such an understanding can provide profound insights into our humanity, leading to fundamentally new computing technologies, and transforming the diagnosis and treatment of brain disorders. Modern ICT brings this prospect within reach. The HBP Flagship Initiative (HBP) thus proposes a unique strategy that uses I ...
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 126

 TERMINÉ 

Smart Nano-objects for Alteration of Lipid-bilayers (SNAL)

Date du début: 1 avr. 2014, Date de fin: 31 mars 2018,

"SNAL is a multidisciplinary programme specially designed to provide scientific and transferable skill training and career development for early stage researchers and experienced researchers in membrane research. Working in a multidisciplinary network will give the researchers a broad perspective on their research field as well as the basic ability of pursuing a research project from basic science ...
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 10

 TERMINÉ 
Cancer, the second most common form of death after cardiovascular disease, is a major European health concern. In 2006, 3.1 million new cases were diagnosed and 1.7 million deaths were attributed to cancer within Europe. The European Commission has a “European Partnership for Action against Cancer” (IP/09/1380) with the aim of reducing the number of cancer cases by 15% by 2020. A key challenge is ...
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 10

 TERMINÉ 
Conduct Disorder (CD) and Oppositional Defiant Disorder with symptoms of Conduct Disorder (which is included among the abbreviation “CD” throughout the proposal) has a highly negative impact for the affected individual as well as for families and society. Although the number of females exhibiting serious aggressive behaviours is growing, the majority of studies on aetiology and treatment of CD hav ...
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 19

 TERMINÉ 

Molecular basis of the outer membrane permeability (TRANSLOCATION)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

Overcoming the barriers that the cell envelope and efflux pumps provide to Gram-negative bacteria is a major bottleneck in the discovery and development of new antibiotics. To respond to this Call we are extending our current network on antibiotic translocation and propose an ambitious project ranging from identification of novel resistance mechanisms in clinical bacterial isolates to crystallizat ...
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 28

 TERMINÉ 

Biodiversity Informatics and Technology Exchange for Snakebite management (BITES)

Date du début: 15 déc. 2013, Date de fin: 14 déc. 2017,

"India is a global hotspot for snakebite mortality, yet management of this significant public health issue requires substantial improvement. Many problems arise from lack of knowledge of the biology of biting species, and much remains to be learned about taxonomy, distribution, and venom characteristics of species such as Russell’s viper (widely considered to be the most dangerous snake in the wor ...
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 4

 TERMINÉ 
Clouds are a very important, yet not well understood feedback factor in climate change and they contribute to the effective radiative forcing (ERF) from aerosol-cloud interactions (ACI). The uncertainty in ERFaci is larger than for any other forcing agent. Also, feedbacks between the terrestrial and marine biosphere and the atmosphere involving ACI are thought to play an important role in regulati ...
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 22

 TERMINÉ 

solving CHAllenges in Nuclear DAta (CHANDA)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2017,

"The CHANDA project main objective is to address the challenges in the field of nuclear data for nuclear applications and its acronym stands for solving CHAllenges in Nuclear DAtaThe project will prepare a proposal for an organization that will coordinate the nuclear data research program, and the infrastructures and capabilities of the EU Member States in a stable structure, well integrated with ...
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 35

 TERMINÉ 
Although the long term prognosis of patients suffering acute myocardial infarction (AMI) has improved since the introduction of reperfusion therapies and primary angioplasty, the 1 year mortality of patients with AMI and resultant left ventricular systolic dysfunction (LVSD) is still as high as 13%. A major reason for the high morbidity and mortality is that the heart has an inadequate regenerativ ...
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 23

 TERMINÉ 

Oral biopharmaceutics tools (ORBITO)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,

The OrBiTo project will deliver novel methods and a framework for rational application of predictive biopharmaceutics tools for oral drug delivery. This will be achieved through novel propsective studies to define new methodlogies which will be validated using historical datasets from EFPIA partners. A combination of high quality in vitro or in silico characterizations of API and formulations will ...
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 28

 TERMINÉ 

Calcium- and light signals in photosynthetic organisms (CALIPSO)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"CALIPSO is a genuine interdisciplinary and intersectorial research network composed of nine academic research institutions and three industrial partners, thus presenting an example of true translational research and training of young researchers in communicating and transferring achievements from different model organisms directly to industrial partners. CALIPSO aims at identifying environmentall ...
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 11

 TERMINÉ 
"The YEASTCELL ITN will train 11 Early Stage Researchers for productive careers as research scientists and leaders in the public or private yeast biotechnology sectors. Yeast biotechnology spans fundamental and applied research and is an area with an immediate need for highly trained researchers to advance knowledge and to develop new applications. The training consortium comprises 9 Public Sector ...
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 13

 TERMINÉ 

MOLECULAR BASIS OF ANTIBIOTIC TRANSLOCATION (Translocation)

Date du début: 1 sept. 2013, Date de fin: 31 août 2017,

Multidrug resistant bacteria are now ubiquitous in both hospitals and the larger community. Drug-resistant pathogens are becoming increasingly pervasive, for example, the resurrection of tuberculosis provides one ominous example highlighting the risk associated with evolved drug resistance. Moreover, many pharmaceutical companies abandoned this field and no truly novel active antibacterial compoun ...
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 11

 TERMINÉ 

Integrated Macro-Financial Modelling for Robust Policy Design (MACFINROBODS)

Date du début: 1 mai 2014, Date de fin: 30 avr. 2017,

"During the global financial crisis and ensuing Great Recession, economists at policy-making institutions had little choice but to augment macroeconomic models with ad-hoc assumptions and adjustments in order to provide analysis and advice for policy makers. Our consortium’s proposal aims to move policy-focused macroeconomic modelling beyond this approach to the endogenous modelling of the dynamic ...
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 12

 TERMINÉ 

All Rights Reserved? Barriers towards EUropean CITIZENship (BEUCITIZEN)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,

The European Court of Justice expects European citizenship to become the fundamental status of nationals of the Member States. It ‘lies at the heart of the European integration process’. The treaties, legislation, and case law have given Europeans an increasing number of rights. Yet the European Commission complains that these remain underused. Therefore, it has included in FP7 a call for a large- ...
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 28

 TERMINÉ 

Multilingual Exploration of Languages in Europe

Date du début: 1 déc. 2014, Date de fin: 31 mars 2017,

... participants 7 Project partners from four European countries (Estonia, Germany, Luxembourg, Spain) will cooperate in the creation of this project, including universities (Talinn University, Goethe University, Université du Luxembourg, Universitat Pompeu) and local schools. Description of activities & methodology to be used in carrying out the project This strategic partnership aims at the develo ...
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 7