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27 projets européens trouvés

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 TERMINÉ 

European Sudden Cardiac Arrest network: towards Prevention, Education and NEw Treatment (ESCAPE-NET)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Sudden cardiac arrest (SCA) causes ~20% of all deaths in Europe. SCA is lethal within minutes if left untreated and survival rates are presently only 5-20%. Therefore, there is a large medical need to improve SCA prevention and treatment. Designing effective individualized prevention and treatment strategies requires knowledge on genetic and environmental risk factors. So far, these efforts have b ...
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 17

 TERMINÉ 

ELIXIR-EXCELERATE: Fast-track ELIXIR implementation and drive early user exploitation across the life-sciences. (ELIXIR-EXCELERATE)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

The life sciences are undergoing a transformation. Modern experimental tools study the molecules, reactions, and organisation of life in unprecedented detail. The precipitous drop in costs for high-throughput biology has enabled European research laboratories to produce an ever-increasing amount of data. Life scientists are rapidly generating the most complex and heterogeneous datasets that scienc ...
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 47

 TERMINÉ 

Intelligent Assessment of Pharmaceutical in the Environment (IPIE)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Active pharmaceutical ingredients (APIs) can be released to the natural environment during the manufacturing process, following use by patients or when unused medicines are disposed of. As APIs are biologically active compounds concerns have been raised about the potential effects of APIs in the environment on human and environmental health. Over the past 15 years, a substantial amount of work has ...
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 29

 TERMINÉ 

Creating medically-driven integrative bioinformatics applications focused on oncology, CNS disorders and their comorbidities (MedBioinformatics) (MedBioinformatics)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2018,

Progress in biomedical research and healthcare requires profiting from the huge amount of data and knowledge that are generated. However, most of the potential users have no means to efficiently exploit this wealth of information. Up to now, many of the efforts done for developing bioinformatics methods and applications have not produced the expected societal impact for different reasons, includin ...
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 13

 TERMINÉ 

Habitat restoration and management in two coastal lagoons of the Ebro Delta: Alfacada y Tancada (Δ-LAGOON)

Date du début: 1 sept. 2010, Date de fin: 31 déc. 2017,

Background The Alfacada and Tancada lagoons are located in the Delta del Ebro Natural Park. Though the Alfacada lagoon is a protected area, it was until recently a private estate used for hunting. It is also vulnerable to the effects of climate change on the water and sediment flux of the Ebro river, which has accelerated the rise in sea level and coasta ...
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 4

 TERMINÉ 

Enhancing prediction of tropical Atlantic climate and its impacts (PREFACE)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2017,

Tropical Atlantic climate recently experienced pronounced shifts of great socio-economic importance. The oceanic changes were largest in the eastern boundary upwelling systems. African countries bordering the Atlantic strongly depend upon their ocean - societal development, fisheries, and tourism. They were strongly affected by these climatic changes and will face important adaptation challenges a ...
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 30

 TERMINÉ 

Innate signaling networks in B cell antibody production: new targets for vaccine development (B-INNATE)

Date du début: 1 avr. 2012, Date de fin: 30 sept. 2017,

The long-term goal of this proposal is to explore a novel immune pathway that involves an unexpected interplay between marginal zone (MZ) B cells and neutrophils. MZ B cells are strategically positioned at the interface between the immune system and the circulation and rapidly produce protective antibodies to blood-borne pathogens through a T cell-independent pathway that remains poorly understood ...
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 1

 TERMINÉ 

Real time monitoring of SEA contaminants by an autonomous Lab-on-a-chip biosensor (SEA-on-a-CHIP)

Date du début: 1 déc. 2013, Date de fin: 31 mai 2017,

Early warning systems that can provide extreme sensitivity with exquisite selectivity are required to assess chemical contamination of estuarine and coastal areas. SEA-on-a-CHIP aims to develop a miniaturized, autonomous, remote and flexible immuno-sensor platform based on a fully integrated array of micro/nano-electrodes and a microfluidic system in a lab-on-a-chip configuration combined with ele ...
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 19

 TERMINÉ 

Seasonal-to-decadal climate Prediction for the improvement of European Climate Services (SPECS)

Date du début: 1 nov. 2012, Date de fin: 31 janv. 2017,

The World Meteorological Organization (WMO) sponsored the Global Framework on Climate Services (GFCS) where the need for actionable climate information for periods from several months up to several years for economic, industrial and political planning has been expressed. However, progress in seasonal forecasting has been slow and decadal forecasting is still incipient. At the same time, new model ...
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 21

 TERMINÉ 

EUropean Provision Of Regional Impact Assessment on a Seasonal-to-decadal timescale (EUPORIAS)

Date du début: 1 nov. 2012, Date de fin: 31 janv. 2017,

Recent advances in our understanding and forecasting of climate and climate change have brought us to the point where skilful and useful predictions are being made. These forecasts hold the potential for being of great value for a wide range of decision-makers who are affected by the vagaries of the climate and who would benefit from understanding and better managing climate-related risks. Howeve ...
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 26

 TERMINÉ 

Priority environmental contaminants in seafood: safety assessment, impact and public perception (ECSAFESEAFOOD)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,

Seafood has been recognized as a high quality, healthy and safe food item. Yet, some seafood can accumulate environmental contaminants with potential impact on human health. Limited information is available for those without maximum limits set by authorities for seafood, like priority contaminants, biotoxins from harmful algal blooms and marine litter. In order to increase seafood safety to consum ...
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 19

 TERMINÉ 

Integrating bioinformatics and chemoinformatics approaches for the development of expert systems allowing the in silico prediction of toxicities (ETOX)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2016,

The eTOX consortium proposes to develop innovative methodological strategies and novel software tools to better predict the toxicological profiles of new molecular entities in early stages of the drug development pipeline. This will be achieved by coordinating the efforts of specialists from academia and SMEs in the wide scope of disciplines that are required to move towards a more reliable modell ...
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 30

 TERMINÉ 

ESTANCIAS INTERNACIONALES PARA ALUMNADO Y PERSONAL DEL PROGRAMA SEFED

Date du début: 1 juin 2014, Date de fin: 31 mai 2016,

Inform Foundation manages since 1987 the SEFED Programme (Simulation for Business Educational Purposes - The Practice Firm concept) which offers training to around 5.000 students delivered by 800 teachers in vocational training institutions and training for the unemployed in Spain. All these students are being trained in professional and social skills in the business and managing of companies fiel ...
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 57

 TERMINÉ 

Physical Activity as a Crucial Patient Reported Outcome in COPD (PRO- ACTIVE)

Date du début: 1 sept. 2009, Date de fin: 31 mai 2016,

Physical activity (PA) is essential in maintaining optimal health in chronic diseases, including COPD.More physically active patients have less hospital admissions and better survival. Validated physicalactivity monitors have become available in recent years, and together with patient report of symptomsand distress of physical (in)activity, this may form a potent new Patient Reported Outcome (PRO) ...
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 20

 TERMINÉ 

Risk of brain cancer from exposure to radiofrequency fields in childhood and adolescence (MOBI-KIDS)

Date du début: 1 mars 2009, Date de fin: 29 févr. 2016,

The rapid worldwide increase in mobile phone use in adolescents and, more recently, children has generated considerable interest in the possible health effects of exposure to radio frequency (RF) fields. The current project aims to assess the potential carcinogenic effects of childhood and adolescent exposure to RF and ELF from mobile telephones on tumours of the central nervous system. The study ...
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 18

 TERMINÉ 

Green eMotion: Development and demonstration of a unique and user-friendly framework for green electromobility in Europe (GREEN EMOTION)

Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,

Green eMotion aims at enabling mass deployment of electromobility in Europe. To achieve this, major players from industry, the energy sector, municipalities as well as universities and research institutions have joined forces to develop and demonstrate a commonly accepted and user-friendly framework consisting of interoperable and scalable technical solutions in connection with a sustainable busin ...
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 44

 TERMINÉ 

Regulation and function of IgD in systemic lupus erythematosus (ACIGDSLE)

Date du début: 1 mars 2011, Date de fin: 28 févr. 2015,

"Anti-nuclear antibodies (ANAs) are the most common types of autoantibodies in SLE. Elevated levels of ANAs belonging to the IgD class have long been observed in SLE patients, reflecting dysregulation of the IgD compartment, but the significance of this dysregulation in SLE pathogenesis is completely unknown. IgD in healthy individuals reacts more frequently with nuclear antigens than IgG, the ant ...
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 1

 TERMINÉ 

Uncovering the Role of Notch Modifiers in the Generation of Hematopoietic Stem Cells in the Embryo (FringEHE)

Date du début: 1 mai 2012, Date de fin: 30 avr. 2014,

Hematopoietic Stem Cell (HSC)-based therapies are becoming a great expectation for the cure of several disorders that require HSCs for treatment. However, the incapacity to generate and maintain fully potent transplantable HSCs in vitro is still nowadays one of the main limitations for their wide application in cellular therapies. The study of the molecular mechanisms underlying HSC ontogeny in em ...
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 1

 TERMINÉ 

Promoting and Monitoring Biomedical Informatics in Europe (INBIOMEDvision)

Date du début: 1 févr. 2011, Date de fin: 31 juil. 2013,

Biomedical Informatics deals with the integrative management and synergic exploitation of the wide ranging and inter-related scope of information that is generated and needed in healthcare settings, biomedical research institutions and health-related industry.Some key present challenges of Biomedical Informatics are:- The effective and synergic integration between computational methods and technol ...
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 7

 TERMINÉ 

Genotype-To-Phenotype Databases: A Holistic Solution (GEN2PHEN)

Date du début: 1 janv. 2008, Date de fin: 30 juin 2013,

"The GEN2PHEN project aims to unify human and model organism genetic variation databases towards increasingly holistic views into Genotype-To-Phenotype (G2P) data, and to link this system into other biomedical knowledge sources via genome browser functionality. The project will establish the technological building-blocks needed for the evolution of today’s diverse G2P databases into a future seaml ...
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 23

 TERMINÉ 

Arrhythmogenic potential of drugs (ARITMO)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2013,

The ability of some compounds to prolong the QT interval of the electrocardiogram and to precipitate Torsade de Pointes (TdP, a potentially fatal arrhythmia) has caused several regulatory interventions, including drug withdrawals. Specific guidelines have been implemented to detect QT liability of new compounds as early as possible. However there is growing evidence that an increase in the QT inte ...
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 21

 TERMINÉ 

Machine for Microparts Moulding based on UltraSound excitation (SONO”R”US)

Date du début: 1 mai 2011, Date de fin: 30 avr. 2013,

"A breakthrough concept in the manufacture of plastic micro and mini parts: the SONO“R”US Project will introduce into the market the first moulding machine based on the ultrasounds. Taking profit of previous results achieved by Sonoplast (Collaborative Project from the FP7), SONO“R”US intends to develop an optimized, ready-to-market ultrasonic moulding machine.Following an increasing trend in mini ...
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 5

 TERMINÉ 

Angiogenesis-inducing Bioactive and Bioresponsive Scaffolds in Tissue Enginering (AngioScaff)

Date du début: 1 déc. 2008, Date de fin: 30 nov. 2012,

Angiogenesis underlies almost all biological processes of morphogenesis, including those in tissue repair and regeneration. Physiological angiogenesis is controlled by a complex interplay between cells and their environment: the extracellular matrix (ECM) provides signaling via numerous ECM adhesion molecules and growth factors bound to ECM polysaccharide components; and cells locally degrade and ...
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 33

 TERMINÉ 

Actinide reCycling by SEParation and Transmutation (ACSEPT)

Date du début: 1 mars 2008, Date de fin: 30 sept. 2012,

"Actinide recycling by separation and transmutation is considered worldwide and particularly in several European countries as one of the most promising strategies to reduce the inventory of radioactive waste, thus contributing to make nuclear energy sustainable. Consistently with potentially viable recycling strategies, the Collaborative Project ACSEPT will provide a structured R&D framework to de ...
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 35

 TERMINÉ 

Management, recycling and recovery of wastes of recreational boat scrapping (BOATCYCLE)

Date du début: 1 janv. 2010, Date de fin: 1 juil. 2012,

Background The leisure sailing sector has grown in recent years in Mediterranean countries. At the beginning of 2007, 43 774 boats were registered in Spain, but by the end of the year a further 11 667 (2 432 in Catalonia) were registered. These boats have a significant environmental impact because after their useful life they become a ‘waste product’ ...
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 3

 TERMINÉ 

Safety Of non-Steroidal anti-inflammatory drugs (SOS)

Date du début: 1 nov. 2008, Date de fin: 30 avr. 2012,

"The Safety Of non-Steroidal anti-inflammatory drugs (SOS) proposal aims to assess the relative cardiovascular (CVD) and gastrointestinal (GI) safety of non-steroidal anti-inflammatory drugs (NSAIDs). The NSAIDs are divided in traditional NSAIDs (tNSAIDs) and the newer COX-II inhibitors(coxibs). The aim will be fulfilled by a two-phase approach comprising systematic reviews and synthesis of CVD an ...
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 11

 TERMINÉ 

Exploring and understanding adverse drug reactions by integrative mining of clinical records and biomedical knowledge (EU-ADR)

Date du début: 1 févr. 2008, Date de fin: 31 janv. 2012,

Serious adverse effects resulting from the treatment with thalidomide prompted modern drug legislation more than 40 years ago. Post-marketing spontaneous reporting systems for suspected adverse drug reactions (ADRs) have been a cornerstone to detect safety signals in pharmacovigilance. It has become evident that adverse effects of drugs may be detected too late, when millions of persons have alrea ...
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 15