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 TERMINÉ 
The problem: finding the right patient for the right treatmentDespite a large and growing disease burden in osteoarthritis (OA), many pharmaceutical companies have de-emphasized or even abandoned OA drug development due to perceived hurdles. Crucial in this is the lack of appropriate outcome measures that can robustly identify patient benefit from a specific therapy. The lack of specific and sensi ...
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 25

 TERMINÉ 
Neuropathic pain has a high incidence in Europe and often affects the patient’s emotional balance and quality of life. Recent meta-analyses have shown that conventional analgesic drugs are not sufficiently effective in these patients and are limited by serious side effects. The search for new analgesics is extremely difficult despite identification of several new potential targets and enormous inv ...
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 12

 TERMINÉ 
"The Strategic Research Agenda of the EU Sustainable Nuclear Energy Technical platform requires new large infrastructures for its successful deployment. MYRRHA has been identified as a long term supporting research facility for all ESNII systems and as such put in the high-priority list of ESFRI. The goal of MAXSIMA is to contribute to the ""safety in MYRRHA"" assessment.MAXSIMA has five technical ...
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 14

 TERMINÉ 

European Lead Factory (EUC²LID)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provi ...
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 34

 TERMINÉ 

Enhanced European Coordination for Accelerator Research & Development (EUCARD-2)

Date du début: 1 mai 2013, Date de fin: 30 avr. 2017,

Research accelerators are facing important challenges that must be addressed in the years to come: existing infrastructures are stretched to all performance frontiers, new world-class facilities on the ESFRI roadmap are starting or nearing completion, and strategic decisions are needed for future accelerators and major upgrades in Europe.While current projects concentrate on their specific objecti ...
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 40

 TERMINÉ 
Despite dramatic advances in molecular and imaging technologies, there are currently no effective pharmacological treatments for the core symptoms of autism spectrum disorder (ASD). Major obstructions to this include a lack of aetiologically-driven or pathophysiologically-accurate animal models; an absence of tests that indicate efficacy; and reliance of clinical trials on DSM/ICD10 categories wh ...
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 29

 TERMINÉ 

Increasing Value and Flow in the Marine Biodiscovery Pipeline (PHARMASEA)

Date du début: 1 oct. 2012, Date de fin: 31 mars 2017,

The PharmaSea project focuses on obstacles in marine biodiscovery research, development and commercialization and brings together a broad interdisciplinary team of academic and industry researchers and specialists to address and overcome these. The partners are ideally placed to demonstrate how to widen the bottlenecks and increase the flow of ideas and products derived from the marine microbiome ...
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 25

 TERMINÉ 
The MastermMind Consortium to avoid dispersing efforts has narrowed the scope of the services to just one, non-organic, mental disorder: depression. This because of its high incidence, social cost and proven clinical effectiveness of ICT in its treatment. MasterMind intends: 1) to implement at scale (almost 5.000 patient overall) evidence based computerised Cognitive Behavioural Therapy (cCBT) ser ...
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 23

 TERMINÉ 

Satiety Innovation (SATIN)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

The SATIN project has been devised to develop food products produced by novel food processing that control satiety through modification of food structure. To achieve this the SATIN project will:1. Integrate advanced technologies to screen novel food structures through in vitro models toisolate and refine products according to their satiating potential.2. Develop novel food processing technologies ...
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 18

 TERMINÉ 
Active therapeutic biodegradable and biocompatible materials are highly in demand. These are required for the production of medicinal products in a variety of areas including implant technology, tissue engineering, drug delivery and wound healing. Within implant technology such biomaterials can be used for dental, bone and cardiovascular implants. Tailored mechanical properties, biocompatibility a ...
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 14

 TERMINÉ 

European-COMPARative Effectiveness research on online Depression (E-COMPARED)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,

In 2010, 30 million Europeans were affected by depression and their number is still growing. Half of Europeans in need of mental care for depression do not have access to care services, do not always receive evidence-based treatments, are confronted with long waiting lists or high care expenditures. Internet-based treatment has the potential to addresses the drawbacks of standard care and keep dep ...
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 16

 TERMINÉ 
The PoLaRBEAR (Production and Analysis Evolution For Lattice Related Barrel Elements Under Operations With Advanced Robustness) project focuses on reliable novel composite aircraft structures based on geodesic technology aiming at a significant higher Robustness and Technology Readiness Level (TRL).While the global structural behavior of composite geodesic structures is investigated and understood ...
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 13

 TERMINÉ 
Accurate quantification of damage in aircraft structures during their life cycle through an automated monitoring system could ensure airframe integrity and long term durability. Nonlinear Elastic Wave Spectroscopy are an innovative class of non-destructive techniques providing an extreme sensitivity in diagnosing manufacturing defects such as porosity, component assembly contact conditions, and in ...
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 10

 TERMINÉ 

SYSTEM-OF-SYSTEMS THAT ACT LOCALLY FOR OPTIMIZING GLOBALLY (Local4Global)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Today's Technical Systems of Systems (TSoS) such as transport, traffic and energy management systems require the deployment of an expensive-to-deploy and operate sensor and communication infrastructure. Moreover, they need a very time/effort-consuming modelling, analysis and control design procedure in order to achieve an efficient performance. On the contrary, Natural Systems of Systems (NSoS) su ...
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 7

 TERMINÉ 
OPTiMiSE (OPtimization of Treatment and Management of Schizophrenia in Europe) will focus on two goals: optimising current treatments in Schizophrenia and explore novel therapeutic options for schizophrenia. The project intends to both address basic, but so far unanswered, questions in the treatment of schizophrenia and develop new and experimental interventions. It is expected that the project wi ...
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 25

 TERMINÉ 
Marine microorganisms form an almost untapped resource of biotechnological potential. However, its use is hindered by the low success rate of isolation of novel microorganisms and often by poor growth efficiency. Hence, the vast majority of marine microorganisms has not been cultivated and is often considered as ‘unculturable’. MaCuMBA aims at improving the isolation rate and growth efficiency of ...
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 24

 TERMINÉ 
The importance of advanced simulation to the competitiveness of both large and small companies is well established. The principal objective of Fortissimo is to enable European manufacturing, particularly small to medium enterprises (SMEs), to benefit from the efficiency and competitive advantage inherent in the use of simulation. However, the simulation of, for example, high-pressure gas cylinders ...
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 96

 TERMINÉ 

e-Justice Communication via Online Data Exchange (e-CODEX)

Date du début: 1 déc. 2010, Date de fin: 31 mai 2016,

The goal of the e-CODEX project is to improve the cross-border access of citizens and businesses to legal means in Europe as well as to improve the interoperability between legal authorities within the EU.Due to high mobility and European integration, procedures containing cross-border effects are increasing. These procedures require cooperation between different national judicial systems.Indeed, ...
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 23

 TERMINÉ 

BIOCERAMICS FOR BONE REPAIR (BIOBONE)

Date du début: 1 mars 2012, Date de fin: 29 févr. 2016,

"There is a general consensus that ceramic based materials should play a very important role in the development of new therapies to treat and substitute damaged or diseased bone. Due to their resistance to wear and corrosion, bioinert technical ceramics are the ideal candidates to replace metallic alloys in a new generation of small, durable and safe orthopaedic implants. On the other hand, osteoc ...
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 9

 TERMINÉ 

Transition Location Effect on Shock Wave Boundary Layer Interaction (TFAST)

Date du début: 1 févr. 2012, Date de fin: 31 janv. 2016,

Vision-2020, whose objectives include the reduction of emissions and a more effective transport systems, puts severe demands on aircraft velocity and weight. These require an increased load on wings and aero-engine components. The greening of air transport systems means a reduction of drag and losses, which can be obtained by keeping laminar boundary layers on external and internal airplane parts ...
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 16

 TERMINÉ 
Organized crime is becoming more diverse in its activities and methods including “greater levels of collaboration between criminal groups, greater mobility in and around the EU, a diversification of illicit activity, and a growing dependence on a dynamic infrastructure, anchored in key locations and facilitated by widespread use of the Internet” (the Director of Europol, in his foreword to the OCT ...
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 19

 TERMINÉ 
Horseback riding attractions are available in more than 30 countries across Europe with considerable economic impact on tourist attractions and becoming more popular due to the close contact with the riders and nature that such activities offers. Horseback activities have available tailored packages for riders of all levels of proficiency, from beginner to advance, including from beginner lessons ...
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 7

 TERMINÉ 
Recent history has shown that in the aftermath of an emergency, disaster or related unexpected events, telecommunication infrastructures play a key role in recovery operations. In most cases, the legacy terrestrial infrastructure is seriously compromised and cannot guarantee reliable services for citizens and rescue teams. It is also well accepted that current public safety networks cannot provide ...
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 18

 TERMINÉ 

Healthy living with EMOCells eco-walls (EMOCELL-HEALTHY-WALL)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2015,

Around the world, drywall construction is a widely used building technique. There exists a broad variety of drywall boards (internal wall panels) on the market, ranging from cheap gypsum boards to expensive wood and clay boards. EMOCell clay-cellulose boards combine all the positive technical characteristics of existing boards (e.g. easy to process and assemble) with high environmental performance ...
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 4

 TERMINÉ 
With up to 20% of electrical energy being consumed by lighting, it is important to use this energy wisely. Replacing the inefficient light generation technologies of today with solid state lighting based on gallium nitride (GaN) light emitting diodes (LEDs) will enable us to reduce this 20% to 10% or even 5%. However, several factors need to be addressed to accelerate the uptake of this emerging ...
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 6

 TERMINÉ 

Glass and Ceramic Composites for High Technology Applications (GLACERCO)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2015,

The aim of this project is to offer a multidisciplinary training in the field of high-tech glasses and composites, in tight contact with companies and universities within this consortium. Our scientific goals are to develop advanced knowledge on glass based materials and to develop innovative, cost-competitive, and environmentally acceptable materials and processing technologies. The inter/multi-d ...
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 9

 TERMINÉ 
In response to world-wide changes in the chemical/biopharmaceutical industry, new market requirements for specific end-use product properties as well as to stricter energy, safety and environmental constraints a revolutionary approach is needed regarding equipment design, plant operation and new production paradigms that will result in better products and processes. Process intensification (PI) is ...
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 14

 TERMINÉ 

Study of Strongly Interacting Matter (HADRONPHYSICS3)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2014,

The Project promotes the access to five European Research Infrastructures, and it is structured into nine Networking Activities, plus the Management of the Consortium, and fourteen Joint Research Activities.The Project will profit of the success of the previous HadronPhysics project in FP6 and the current HadronPhysics2 in FP7, and originates from the initiative of more than 2.500 European scienti ...
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 52

 TERMINÉ 

Gliders for Research, Ocean Observation and Management (GROOM)

Date du début: 1 oct. 2011, Date de fin: 31 déc. 2014,

Underwater gliders are intelligent and affordable platforms, useful for long-term, multi parameter marine observations. Because of their remotely controlled navigational capabilities and the high spatial and temporal resolution of their measurements in real-time, gliders have been identified to fill gaps existing in the existing ocean observing systems. Along with there rapidly growing importance ...
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 21

 TERMINÉ 

PlanetData

Date du début: 1 oct. 2010, Date de fin: 30 sept. 2014,

Description The PlanetData project aims to establish an interdisciplinary, sustainable European community of researchers, helping organizations to expose their data on the Web PlanetData will push forward the state-of-the-art in large-scale data management and its application to the creation of us ...
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 22

 TERMINÉ 

Large Area Photonic Crystal Chemical Sensors (PHOTOSENS)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2014,

The PHOTOSENS project aims to develop a low-cost, mass-manufacturable, nano-structured, large-area multi-parameter sensor array using Photonic Crystal (PC) and enhanced Surface Enhanced Raman Scattering (SERS) methodologies for environmental and pharmaceutical applications. Integrating the PC and SERS based sensors with integrated optics coupling structures within a single sensor platform allows t ...
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 9

 TERMINÉ 
Objective: To delineate the biological and molecular pathways that initiate and drive chronic inflammatory disease and to transform the knowledge obtained into the development of novel anti-inflammatory interventions. Focus will be given to Rheumatoid Arthritis (RA) since longitudinal data indicate that intensive treatment can prevent persistency and chronicity. State of the Art and beyond: The ...
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 20

 TERMINÉ 

Advanced Lattice Structures for Composite Airframes (ALaSCA)

Date du début: 1 déc. 2010, Date de fin: 30 nov. 2013,

The ALaSCA project focuses on maximum weight and cost reduction significant in airframes by developing manufacture-optimized lattice fuselage structures fulfilling fundamental aspects of airworthiness.The idea behind the ALaSCA project is to perform a comprehensive investigation starting with the beneficial geodesic design well-proven in space technology and transferring it to composite aircraft f ...
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 13

 TERMINÉ 
Energy storage is recognised as a key element for energy networks in the near future. Regarding short-term power delivery and high duty cycle applications, such as stabilization of grids, traction networks and drive-trains of hybrid or full-electric vehicles, it is widely accepted that the use of energy storage systems (ESS) can lead to energy savings. This kind of networks needs ESS capable of st ...
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 7

 TERMINÉ 
"Photoprotection against excess absorbed light energy is an essential and universal attribute of oxygenic photosynthetic organisms. This requirement has been a strong force in the evolution of plants and micro-organisms, and a diverse range of solutions have arisen. It has determined survival, productivity and habitat preference, and it determines the ceiling on the efficiency of energy conversion ...
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 18

 TERMINÉ 
Europe has a leading position in eco-innovation patents and emerging technologies. Although the EU achieves a remarkably high annual growth rate of 16% in eco-innovation, transfer to SMEs is rather low. Technology transfer to SMEs would be important to reduce EU’s industrial pollution. According to OECD and EC reports, awareness for RTD results is low. There is a need to increase technology transf ...
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 8

 TERMINÉ 
"Scientists try to develop coatings that prevent of fouling. Development of new coating formulation takes 5 years, beginning from R&D study to the date of launching. Taking into account the marine market development and the change of low requirements connected to the environmental issues this time is too long. Formulation time distances depend mainly on testing. In Europe the only method is testin ...
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 7

 TERMINÉ 

Simple Procedures Online for Crossborder Services (SPOCS)

Date du début: 1 mai 2009, Date de fin: 31 déc. 2012,

Description A European project to ease the administrative burden of businessesSimple Procedures Online for Cross-border Services (SPOCS) is a pilot project launched by the European Commission which aims to remove the administrative barriers European businesses face in offering their services abroad. SPOCS is expected to further enhance th ...
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 33

 TERMINÉ 

Hotspot Ecosystem Research and Man's Impact on European seas (HERMIONE)

Date du début: 1 avr. 2009, Date de fin: 30 sept. 2012,

The HERMIONE project is designed to make a major advance in our knowledge of the functioning of deep-sea ecosystems and their contribution to the production of goods and services. This will be achieved through a highly interdisciplinary approach (including biologists, ecologists, microbiologists, biogeochemists, sedimentologists, physical oceanographers, modelers and socio-economists) that will in ...
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 41

 TERMINÉ 
"Multiple sclerosis (MS) is a chronic inflammatory, disabling disease of the central nervous system. Recent studies suggest that over the last 50 years a disproportional increase in incidence of MS in women has taken place. The lifetime costs of MS exceed 1.5 million € per case in the UK, and are likely to be similar in other European countries. There is no definitive cure for MS. Immunomodulatory ...
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 12