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 TERMINÉ 

GENEtic DiSsection of Innate Immune Sensing and Signalling (GENESIS)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,

In vertebrates, a receptor-based, innate sensing machinery is used to detect the presence of microbederived molecules or the perturbation microbial infection causes within the host. In the context of viral infection, non-self nucleic acids are sensed by a set of intracellular receptors that upon activation initiate broad antiviral effector responses to eliminate the imminent threat. Over the past ...
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 TERMINÉ 
Groundwater resources are facing increasing pressure from consumptive uses (irrigation, water supply, industry) and contamination by diffuse loading (e.g. agriculture) and point sources (e.g. industry). This cause major threat and risks to our most valuable water resource and on ecosystems dependent on groundwater. New information is need on how to better protect groundwaters and groundwater depen...
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 28

 TERMINÉ 

GENeric European Sustainable Information Space for Environment (GENESIS)

Date du début: 1 sept. 2008, Date de fin: 31 août 2011,

The GENESIS Project has the objective of providing Environment management and Health actors with an innovative solution based on advanced ICT. Relying on interoperability standards and harmonization process, GENESIS helps to constitute complex information networks, by combining benefits of various information systems with a collaborative systems approach. The proposed generic solution allows easy ...
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 29

 TERMINÉ 

Molecular and Cellular Mechanisms of Glioma Genesis (Gliomagenesis)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,

Glioblastoma (GBM) is the most aggressive form of glioma, the most common primary brain cancer in adults. GBM is highly resistant to standard radiotherapy and chemotherapy treatments and thus represents a leading cause of cancer-related death worldwide. Although many genetic alterations have been identified for GBM, its histogenesis is still poorly understood. The relative contribution of each gen...
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 1

 TERMINÉ 
Transposable elements (TEs) account for more than two thirds of the human genome. They can inactivate genes, provide novel coding functions, sprinkle chromosomes with recombination-prone repetitive sequences, and modulate cellular gene expression through a wide variety of transcriptional and posttranscriptional influences. As a consequence, TEs are considered as essential motors of evolution yet t...
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 1

 TERMINÉ 
The project, carried out by 3 member institutions of the European Consortium of Innovative Universities, will develop and test a 'Master Programme in Management of Innovation and Entrepreneurship (MMIE)' aimed at mid-career professionals. It will provide 'entrepreneurial change agents' with techniques to empower small firm owners and managers with the necessary skills to run their companies in a d...
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 10

 TERMINÉ 

Molecular Mechanisms of Glioma Genesis and Progression (Glioma)

Date du début: 1 août 2008, Date de fin: 31 juil. 2014,

Glioma is the most common and aggressive tumour of the brain and its most malignant form, glioblastoma multiforme, is nowadays virtually not curable. Very little is known about glioma genesis and progression at the molecular level and not much progress has been achieved in the treatment of this disease during the last years. The understanding of the molecular mechanisms involved in the biology of ...
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 3

 TERMINÉ 

GENESIs: Green sEnsor NEtworks for Structural monItoring (GENESI)

Date du début: 1 avr. 2010, Date de fin: 31 août 2013,

The aftermath of too many dramatic events involving public structures and private buildings collapse makes imperative to ask ourselves whether anything can be done to mitigate their effects or avoid them and save the lives taken as a result of their occurrence. Wireless sensor network (WSN)-based systems for structural health monitoring could be the answer to this crucial question were they able t...
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 7

 TERMINÉ 

Oncogene-induced DNA damage as driver of B cell lymphoma genesis (OncIndLymph)

Date du début: 1 mars 2014, Date de fin: 28 févr. 2018,

Recurrent oncogenic chromosomal rearrangements are a hallmark of lymphoid malignancies and are considered to be the driving force in tumor survival and progression. While oncogenes typically induce uncontrolled proliferation, they also induce metabolic stress and constitutive DNA damage. Hence, at the time of diagnosis tumor genomes are typically highly mutated. Not surprisingly, forced expression...
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 2

 TERMINÉ 
Supported metal nanoparticles are used as catalysts to accelerate and steer chemical conversions to produce, e.g., transportation fuels, chemicals and medicines. Albeit of eminent importance, supported metal catalysts are almost exclusively synthesized in liquid-phase processes that are often considered ‘an art rather than a science’. Although recent results from our laboratory and others on the f...
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 1

 TERMINÉ 
"The project aims to explore and synthesize the history of modern public visual production and consumption in Southern Africa. It is based on the assumption that the varied Southern African visual economies are framed and patterned by a South African claim to hegemonic control of visual production and communication. As in many other realms of society the country's imperial outreach on its neighbor...
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 1

 TERMINÉ 

MIRRORS OF DEMOCRACY

Date du début: 26 juin 2014, Date de fin: 26 mars 2015,

This European encounter, " Mirrors of democracy", will assemble 50 young participants, in two towns or villages of the North Cantal - Menet and Riom-ès-Montagnes - from July 5 to 26, 2014, who come from the Ukraine, Georgia, Armenia, Portugal, Poland, Bulgaria and France, to reflect and act together on the subject of the great contemporary democratic issues. This will mean 21 days of encounters b...
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 7

 TERMINÉ 
The discovery of pluripotent stem cells has expanded the working modes in biology towards the reverse engineering of specific cell types. Unlike studying developmental phenomena in vivo, we are now theoretically able to mimic some of these processes in a dish. The use of human induced pluripotent stem (iPS) cells facilitates studying the genesis of human cell types in an ethically approved setting...
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 1

 TERMINÉ 

COMPARATIVE EDUCATION THEORY (CETH)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2015,

"The proposed project is an interdisciplinary theoretical investigation in the field of comparative education studies. The main purpose is to create a knowledge base intended to contribute to our understanding of education systems across cultures, under the conditions created by the Europeanisation and globalisation of education policy.These novel conditions indicate that it is time to improve ou...
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 1

 TERMINÉ 
The genesis of the modern constitutional state in late 18th and 19th century Europe has met im-mense public awareness and cross-border participation. Though this phenomenon is well known, basic patterns of constitutional communication (i.e. socio-cultural and cross-border contexts, ‘Zeitgeist’) have never been addressed before. In this concern ReConFort applies an evolutionary, dynamic and interac...
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 1

 TERMINÉ 

Ethnic Minorities in the European Union

Date du début: 1 sept. 2014, Date de fin: 31 août 2017,

The overall objectives of the EMEU project – the expansion of knowledge of students and other members of the academic community of the BSU, other educational institutions in Belarus on historical, social, legal and other problems of genesis and existence of ethnic minorities in the EU through the development and implementation into the educational process of the Faculty of History of the BSU new t...
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 1

 TERMINÉ 
Lymphoid cancers are among the most common human malignancies and characteristically harbour genomic aberrations. Although databases will soon be flooded with genome sequences from thousands of tumours, interpretation and validation of these data is limited by the genetic variability and uncontrolled environmental exposures inherent to human studies. There is therefore a growing need in complement...
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 1

 TERMINÉ 
"The changing business ecosystem and the major transformations that organizations are experiencing today have a common denominator: Information and Communication Technologies (ICT). ICT are pervasive and ubiquitous and all business or social activities are now generating a corresponding digital data event. We call this ubiquitous and massive creation of real time data in a natively digital form Di...
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 1

 TERMINÉ 
Engaging with one of the most important elements of Europe’s cultural heritage, this project employs material evidence and technological tools to analyse relationships among texts in the Middle Ages. The Trojan narrative constitutes an ideal case for considering networks of texts. Not only did the story of the conquest of Troy by the Greeks provide some of the most important literary motifs for an...
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 1

 TERMINÉ 

RHUM-RUM: Imaging a mantle plume under the hotspot of La Réunion (RHUM-RUM)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2018,

"RHUM-RUM is a seismological experiment designed to image an oceanic mantle plume – or lack of plume – from crust to core beneath La Réunion Island, and to understand these results in terms of material and heat flows. The Réunion hotspot is one of the most active volcanoes in the world, and its hotspot track leads to the Deccan Traps of India, one of the largest flood basalt provinces on Earth, wh...
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 1

 TERMINÉ 
The project addresses critical gaps in our understanding of the role of genome duplication (polyploidy) in the genesis and maintenance of plant diversity. While polyploidization is widely acknowledged as a major speciation mechanism in land plants, little is still known about the performance, dynamics, and evolutionary potential of wild polyploid lineages. In my project I propose an interdisciplin...
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 1

 TERMINÉ 
F-Interop will develop and provide remotely accessible tools to support and accelerate standardisation processes and products developments, by offsetting several cost and time barriers. It will research and develop a new FIRE experimental platform to support the development of new technologies and standards, from their genesis to the market for: online interoperability tests and validation tools, ...
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 12

 TERMINÉ 
Late medieval European court cultures have traditionally been studied from a mono-disciplinary and national(ist) perspective. This focus has obscured much of the interplay of cultural performances that informed “courtly life”. Recent research has begun to reverse this, focusing on issues such as the tensions between orality, writing, and performance; the sociocultural dimensions of making and owni...
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 1

 TERMINÉ 
There is an intense interest in the function of human Myc proteins that stems from their pervasive role in the genesis of human tumors. A large body of evidence has established that expression levels of one of three closely related Myc proteins are enhanced in the majority of all human tumors and that multiple tumor entities depend on elevated Myc function, arguing that targeting Myc will have sig...
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 3

 TERMINÉ 
Based on epidemiological evidence supporting an ssociation between residential exposure to extremelylow frequency magnetic fields (ELF MF) and childhood leukaemia, ELF MF have been classified as possibly carcinogenic to humans. The proposed project aims to scrutinize the underlying biophysical mechanisms andto clarify a possible causal relationship between ELF MF exposure and cancer, especially ch...
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 9

 TERMINÉ 
The establishment and maintenance of cellular polarity are critical for organ function. In addition to the ubiquitous apicobasal axis, many epithelial cells display a second polarity axis within the plane of the tissue, referred to as planar cell polarity. The orientation of hair-cell stereocilia in the inner ear represents a striking example of planar polarity in vertebrates. Although many of the...
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 1

 TERMINÉ 

Mitochondrial DNA degradation and sterile inflammation in the heart (RAMBO)

Date du début: 1 sept. 2016, Date de fin: 31 août 2021,

Heart failure is the leading cause of morbidity and mortality in developed countries including EU. Novel and efficient therapeutics to treat patient with heart failure have to be developed. Mitochondria are subcellular organelles that produce energy and dynamic organelles that fuse and divide. Dysregulated mitochondrial activity results in generation of free radicals which cause damage to cellular...
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 TERMINÉ 
A fundamental question in neuroscience is to reveal the energy constrains governing the plasticity of brain circuits. Mitochondrial energy metabolism is increasingly recognized for regulating the activity and integrity of existing synaptic terminals, however it is unclear how changes in mitochondrial function are coupled with the generation of new neurons and the ensuing circuit remodelling, e.g. ...
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 2

 TERMINÉ 
One of the prominent features of Medieval Aristotelianism, both Arabic and Latin, is the fact that Aristotle has been credited with writings that, albeit Neoplatonic in origin, circulated under his name. Crucial as it might be for the genesis of Arabic-Islamic philosophy, the main text of the Neoplatonic tradition into Arabic, i.e., the so-called Theology of Aristotle, is still poorly edited and n...
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 3

 TERMINÉ 

Transgenic models of mammalian meiotic exit (Perry/mII/tg)

Date du début: 1 avr. 2010, Date de fin: 31 mars 2014,

Fertilisation occurs when two highly specialised cells (sperm and egg) unite, causing an 'awakening' of the egg, known as meiotic exit. During meiotic exit, a one-cell embryo (zygote) is formed that is totipotent - it can give rise to an entire individual. Given the fundamental nature of this event, it is remarkable that almost nothing is known about the regulation of meiotic exit in mammals. Igno...
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 1

 TERMINÉ 
Continuum is a LL Erasmus Multilateral Project that aims at putting together schools of architecture and small to medium-sized enterprises to exchange research results, information, ideas, techniques, methods and expertise in the domain of design-to-manufacturing. A large number of contemporary buildings is generated through parametric design, that is the design of forms with the irreplaceable aid...
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 13

 TERMINÉ 
Chemical exchanges between the lithosphere-ocean-atmosphere are focused at the active plate boundaries and are important in the global geochemical balance. Eventually, they may influence climate and impact on human activities. Hydrothermal circulation at these boundaries is the engine that transfers chemicals between the lithosphere and ocean. However, the structure of lithospheric contribution (h...
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 1

 TERMINÉ 

BIOLOGIE 2.0

Date du début: 12 déc. 2013, Date de fin: 11 juin 2016,

A new genesis is under way. After the dramatic advances in genomics, 21st century biology is also heading for a revolution : moving into the era of synthesis.Its ways and means : making evolution evolve, synthesizing genes, building genomes… decrytping, encrypting and re-encrypting the very building blocks of life, DNA, and manipulating them like simple Lego bricks, programming them, like mechanic...
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 2

 TERMINÉ 
"Biodiversity hotspots are regions where exceptional concentrations of endemic species face extraordinary levels of habitat loss. The evolutionary processes determining the genesis and maintenance of such high biodiversity are poorly understood. REVOL uses population genomics in a multi-disciplinary context to uncover the neutral and adaptive evolutionary processes responsible for recent and ongoi...
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 1

 TERMINÉ 

Axoglial synapses, adult myelination and motor skills learning (MOTOGLIA)

Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,

"Recently it has become clear that new oligodendrocytes and myelin are generated throughout adult life in rodents. Some major axon tracts including the corpus callosum contain a majority of unmyelinated axons even in maturity, suggesting that at least some of the adult-born oligodendrocytes might myelinate previously naked axons. This would be expected to alter dramatically the conduction proper...
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 1

 TERMINÉ 
Neuroscientific research suggests a link between the style of caricature and neurocognitive procedures of perception: the brain perceives reality and makes sense of it by isolating and emphasising patterns. Similarly, by misshaping and exaggerating visual features, caricature provides an enhanced perception of facts and feelings, uncovers hidden aspects of reality, and reveals unconventional knowl...
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 1

 TERMINÉ 
"HIMWARC will extend our fundamental knowledge and concomitantlyrestrain present levels of uncertainty with respect to future changes of highimpact weather in the Arctic.The weather in the Arctic features several severe types of extremes suchas polar lows and strong low-level winds in the vicinity of topography. Theseextremes rigorously influence the socio-economic structure of the affectedregions...
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 TERMINÉ 
The genesis of our project "Training for students and teachers from Liceul Tehnologic PETROL Moreni for VET at European standards" emerged from the need to reinvigorate the technical education in our school; the new Erasmus+ programme allowed us to approach the educational process through the strategic priorities for European cooperation in education and training. Analyzing the training needs of...
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 2

 TERMINÉ 

Model Discover Manipulate: a method for non formal learning of mathematics

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2018,

The PISA results (2012) show that 22.1% of European students were low achievers in maths. Which means that more than one out of five youngsters in Europe is not equipped with that basic skill necessary for numerous valuable job in our current economy. The Commission has the objective to lower this number to 15% in 2020 but, so far, in many countries the progression is weak when the level is not si...
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 5

 TERMINÉ 

Market-Based Initiatives as Solutions to Techno-Scientific Problems (MISTS)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2018,

MISTS engages with market based initiatives employed as potential solutions to techno-scientific problems. MISTS will draw together two strands of STS research: the turn to research on markets and STS literature on science problems (and solutions). These two areas will be drawn on in exploring four sub-projects which feature market based initiatives as solutions to problems: an attempt to build a ...
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