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 TERMINÉ 

Re-wetting valuable raised bogs in the northern Hannover Region (Hannoversche Moorgeest)

Date du début: 1 sept. 2012, Date de fin: 31 août 2023,

Background Lower Saxony takes a lead nationally in the conservation of raised bogs, as 95% of all bogs in the Atlantic area are located in this German region. In Lower Saxony’s network of Natura 2000 sites, significant areas of raised bog habitats are found in the Helstorfer, Otternhagener and Schwarzes Moor bogs, as well as in the Bissendorfer Moor bog ...
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 2

 TERMINÉ 

Ocean Energy ERA-NET Cofund (OCEANERA-NET COFUND)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

AbstractOCEANERA-NET COFUND aims at coordinating the efforts of 8 agencies, in 4 Member states and 4 regions, in the ocean energy area. The joint action will focus on the demonstration and validation of innovative technologies for the generation of electricity from waves, tidal current, tidal range, salinity gradient and ocean thermal energy conversion, which will lead to improved performance, rel ...
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 8

 TERMINÉ 

Healthy minds from 0-100 years: Optimising the use of European brain imaging cohorts (Lifebrain)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

...tal health measures for extensively broader cohorts, exceeding 40.000 examinations in total. By linking these data, also to additional databases and biobanks, including birth registries, national and regional archives, and by enriching them with new online data collection and novel measures, we will address risk and protective factors of brain, cognitive and mental health throughout the lifespan. ...
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 16

 TERMINÉ 

European Human Biomonitoring Initiative (HBM4EU)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The overarching goal of the European Human Biomonitoring Initiative (HBM4EU) is to generate knowledge to inform the safe management of chemicals and so protect human health. We will use human biomonitoring to understand human exposure to chemicals and resulting health impacts and will communicate with policy makers to ensure that our results are exploited in the design of new chemicals policies an ...
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 43

 TERMINÉ 

European Sudden Cardiac Arrest network: towards Prevention, Education and NEw Treatment (ESCAPE-NET)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Sudden cardiac arrest (SCA) causes ~20% of all deaths in Europe. SCA is lethal within minutes if left untreated and survival rates are presently only 5-20%. Therefore, there is a large medical need to improve SCA prevention and treatment. Designing effective individualized prevention and treatment strategies requires knowledge on genetic and environmental risk factors. So far, these efforts have b ...
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 17

 TERMINÉ 

Reaching the effects of gastric bypass on diabetes and obesity without surgery (BYPASSWITHOUTSURGERY)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

...ational scope, all elements involved in these responses will be addressed in this project, from detailed analysis of food items responsible for hormone secretion, to identification of the responsible regions of the gut, and to the molecular mechanisms leading to hypersecretion. Novel approaches for studies of human gut hormone secreting cells, including specific expression analysis, are combined w ...
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 2

 TERMINÉ 

Multiple manifestations of genetic and non-genetic factors in Multiple Sclerosis disentangled with a multi-omics approach to accelerate personalised medicine (MultipleMS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The complex interactions between genetic and non-genetic factors produce heterogeneities in patients as reflected in the diversity of pathophysiology, clinical manifestations, response to therapies, disease development and progression. Yet, the full potential of personalized medicine entails biomarker-guided delivery of efficient therapies in stratified patient populations.MultipleMS will therefor ...
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 25

 TERMINÉ 

EUROlinkCAT: Establishing a linked European Cohort of Children with Congenital Anomalies (EUROlinkCAT)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

... optimisation of personalised care and treatment decisions for children with rare CAs. Registries will be supported in using social media platforms to connect with families who live with CAs in their regions. A novel sustainable e-forum, “ConnectEpeople”, will link these families with local, national and international registries and information resources. ConnectEpeople will involve these families ...
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 25

 TERMINÉ 

Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’: A Randomized Controlled Multicentre Trial (PAPA-ARTIS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time but continue to increase in diameter before they eventually rupture. Left untreated, the patients’ prognosis is dismal, since the internal bleeding of the rupture brings about sudden death. Although successful treatment cures the disease, the risky procedures can result in ...
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 26

 TERMINÉ 

Clinical development and proof of principle testing of new regenerative VEGF-D therapy for cost-effective treatment of refractory anginaA phase II randomized, double-blinded, placebo-controlled study (ReGenHeart)

Date du début: 1 janv. 2017, Date de fin: 30 juin 2021,

Chronic angina pectoris is a debilitating chronic disease, a subgroup of these patients suffers from refractory angina which unfortunately can’t be controlled by medical therapy (angioplasty or surgery). Refractory angina is a substantial burden on the individual and healthcare system, in Europe there are 100,000 new cases per year, annual mortality of these patients is relatively low (
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 10

 TERMINÉ 

Towards evidence-based tailored implementation strategies for eHealth (ImpleMentAll)

Date du début: 1 janv. 2017, Date de fin: 31 mars 2021,

ImpleMentAll will develop, apply, and evaluate tailored implementation strategies in the context of on-going eHealth implementation initiatives in the EU and beyond. Common mental health disorders account for an alarming proportion of the global burden of disease. Being regarded as an evidence-based psychotherapeutic eHealth intervention, Internet-based Cognitive Behavioural Therapy (iCBT), has th ...
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 19

 TERMINÉ 

RECAP: Research on European Children and Adults born Preterm (RECAP)

Date du début: 1 janv. 2017, Date de fin: 31 mars 2021,

The project’s overall aim is to improve the health, development and quality of life of children and adults born very preterm (VPT, < 32 weeks of gestation) or very low birth weight (VLBW, < 1500g) – approximately 50 000 births each year in Europe – by establishing an ICT platform to integrate, harmonise and exploit the wealth of data from 20 European cohorts of VPT/VLBW children and adults and the ...
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 21

 TERMINÉ 

SUrvey Network for Deep Imaging Analysis and Learning (SUNDIAL)

Date du début: 1 avr. 2017, Date de fin: 31 mars 2021,

Though Big Data has become common in many domains nowadays, the challenges to develop efficient and automated mining of the ever increasing data sets by new generations of data scientists are eminent. These challenges span wide swathes of society, business and research. Astronomers with their high-tech observatories are historically at the forefront of this field, but obviously, the impact in e.g ...
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 9

 TERMINÉ 

ERA-NET for materials research and innovation (M-ERA.NET 2)

Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,

M-ERA.NET 2 aims at coordinating the research efforts of the participating EU Member States, Associated States and Regions as well as of selected global partners in materials research and innovation, including materials for low carbon energy technologies and related production technologies.A large network of 43 national and regional funding organisations from 23 EU Members States and Associated St ...
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 43

 TERMINÉ 

AcceLerate Innovation in urban wastewater management for Climate changE (ALICE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The challenges facing society in urban wastewater management cannot be solved by any one sector alone. ALICE (AcceLerate Innovation in urban wastewater management for Climate changE) will accelerate innovation by bringing together and exchanging knowledge between the key players who can, together, address the future techno-economic, governance and societal challenges arising from climate change. I ...
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 13

 TERMINÉ 

“In Vivo Click PET Imaging Agents”: Improving clinical companion diagnostics (Click-It)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Companion diagnostics are crucial for drug development and disease management with regard to patient selection, therapy planning and monitoring. Nanomedicines such as antibodies have been proven to be optimal disease-targeting agents because they generally exhibit superior target uptake and retention. However, to date, nuclear imaging of nanomedicines has been limited to the use of long-lived isot ...
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 6

 TERMINÉ 

Comorbidity and Synapse Biology in Clinically Overlapping Psychiatric Disorders (COSYN)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

COSYN integrates outstanding European academic and three large Pharma to exploit genomic findings for intellectual disability (ID), autism, and schizophrenia. We capitalise on comorbidity, from clinic to cells and synapses, and have access to large existing samples. We focus on rare genetic variants of strong effect in patients with clinical comorbidity. Our aims are: (1) Understand comorbidity by ...
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 14

 TERMINÉ 

Technology Enabled Adolescent Mental Health (TEAM)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,

There is no health without mental health. 27% of our population are young, and mental health disorders are our leading cause of disability. 50% of mental disorders emerge by 14 yrs, 75% by 24 yrs and, untreated, triple odds of having a mental health disorder in later life. TEAM’s will build a network of expertise and train a new generation of researchers to deliver more effective, affordable and f ...
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 9

 TERMINÉ 

MACRO CASCADE – Cascading Marine Macroalgal Biorefinery (MACRO CASCADE)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,

MACRO CASCADE will prove the concept of the cascading marine macroalgal biorefinery i.e. a production platform that covers the whole technological chain for processing sustainable cultivated macro-algae biomass – also known as seaweed - to highly processed value added products. The macro-algae biorefinery will be capable of processing multiple feedstocks, by deploying a range of mechanical, phy ...
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 13

 TERMINÉ 

Molecular imaging and targeted therapy of the aggressive phenotype: development of uPAR theranostics for cancer patients (uPET)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,

For practice of personalized medicine in cancer, non-invasive tools for diagnosing at the molecular level are needed. Molecular imaging methods are capable of this while at the same time circumventing sampling error as the whole tumor burden is evaluated.We recently developed and performed the first-ever clinical PET scan of uPAR, a proteolytic system known to be strongly associated with metastati ...
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 1

 TERMINÉ 

Breast Cancer Risk after Diagnostic Gene Sequencing (BRIDGES) (BRIDGES)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

Breast cancer affects more than 360,000 women per year in the EU and causes more than 90,000 deaths. Identification of women at high risk of the disease can lead to disease prevention through intensive screening, chemoprevention or prophylactic surgery. Breast cancer risk is determined by a combination of genetic and lifestyle risk factors. The advent of next generation sequencing has opened up th ...
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 20

 TERMINÉ 

South Moravian Programme for Distinguished Researchers 3 (SoMoPro 3)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

SoMoPro 3 is an innovated regional fellowship programme building on its two predecessors, SoMoPro (2009–2013) and SoMoPro II (2012–2017). The program was established in 2009 after a successful application to the COFUND scheme. Since then 4 calls for proposals have been open: in 2009, 2010 and 2012, 2013 with 53 fellowships funded. The objective of this application is to launch 2 more calls and sup ...
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 1

 TERMINÉ 

Metal oxide Aided Subsurface Remediation: From Invention to Injection (METAL-AID)

Date du début: 1 juil. 2016, Date de fin: 30 juin 2020,

Thousands of sites across Europe are polluted with toxic metals and organic solvents; many more exist worldwide. As EU population grows, clean water will determine the quality of life and economic stability. Most sites remain contaminated because existing technology is costly and disruptive. Society needs an innovative way to decontaminate soil and groundwater directly underground. In METAL-AID, w ...
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 11

 TERMINÉ 

Mobile Assistance for Groups Individuals within the Community - STROKE REHABILITATION (MAGIC)

Date du début: 1 janv. 2016, Date de fin: 30 avr. 2020,

MAGIC Post Stroke Project Team has united members from across Europe, dedicated to enable significant change in the delivery of health & social care (H&SC) services for patients post stroke. The consortium has recognised a significant gap in care associated with the recovery of such patients & we need a new way of meeting the needs of 508,000 new post stroke EU citizens/ year. Demographic changes ...
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 14

 TERMINÉ 

A Federated Collaborative Care Cure Cloud Architecture for Addressing the Needs of Multi-morbidity and Managing Poly-pharmacy (C3-Cloud)

Date du début: 1 mai 2016, Date de fin: 30 avr. 2020,

...tion. To demonstrate feasibility, pilot studies will focus on diabetes, heart failure, renal failure, depression in different comorbidity combinations. Pilots will operate for 15 months in 3 European regions with diverse health and social care systems and ICT landscape, which will allow for strengthening the evidence base on health outcomes and efficiency gains. C3-Cloud adaptive patient pathways ...
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 12

 TERMINÉ 

Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2020,

Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
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 44

 TERMINÉ 

Procuring innovative ICT for patient empowerment and self-management for type 2 diabetes mellitus (ProEmpower)

Date du début: 1 oct. 2016, Date de fin: 31 mars 2020,

...rs and (IV) effectiveness proven in a trial with 200 patients and 40 professionals. Fully rolled out in the four countries, enabled by procurers with the authority and capacity in their countries and regions, ProEmpower will serve 12 million diabetes patients. Reductions in diabetes-related death, amputation, blindness and renal failure promise cost relief of € 53 billion over 7 years in the four ...
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 9

 TERMINÉ 

WADI

Date du début: 1 oct. 2016, Date de fin: 31 mars 2020,

...timized wavelengths (suitable particularly for water leaks detection), the WADI technology will be applied in an operational environment represented by two pilot sites, i.e. in France (Provence region, case of water supply mains) and Portugal (Alqueva, case of multi-purpose mains serving irrigation, water supply, and hydro power). The WADI proposal addresses the challenge of building a water (and ...
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 12

 TERMINÉ 

Evidence-based ICT tools for weight loss maintenance (NoHoW)

Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,

Most adults who try to lose weight fail to maintain it. Obesity is a key economic and healthcare challenge for Europe. Effective interventions and commercial programmes for weight loss are widely available, but most people re-gain their lost weight. Currently few comprehensive solutions exist to help Europeans manage weight loss maintenance (WLM).Current research suggests the most promising eviden ...
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 16

 TERMINÉ 

Consolidating the European Research Area on biodiversity and ecosystem services (BiodivERsA3)

Date du début: 1 févr. 2015, Date de fin: 31 janv. 2020,

...this challenge and providing scientific support to stakeholders and policy makers requires a coherent interdisciplinary research framework, with coordinated strategies and programmes at the national, regional and international levels, which are the relevant scales for many biodiversity issues.By networking 32 funding agencies from 18 countries, BiodivERsA3 aims to strengthen the ERA on biodiversit ...
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 31

 TERMINÉ 

European Gram Negative Antibacterial Engine (ENABLE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
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 42

 TERMINÉ 

Translating neuroimaging findings from research into clinical practice (PSYSCAN)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

Abstract 9Neuroimaging (NI) has enormous potential to improve the clinical care of patients with psychiatric disorders, but has yet to deliver. The PSYSCAN project will address this issue directly by developing a NI-based tool that will help clinicians resolve key clinical issues in the management of patients with psychotic disorders. Clinicians will use the tool to assess patients with a standard ...
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 24

 TERMINÉ 

MANAGEMENT OF BIOMASS ASH AND ORGANIC WASTE IN THE RECOVERY OF DEGRADED SOILS: A PILOT PROJECT SET IN PORTUGAL (LIFE No_Waste)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Background Mining operations are a cause of soil degradation. They are associated with a legacy of abandoned metalliferous mine wastes and acid mine drainage, which contributes to around 2% of soil contamination in Europe. There is therefore an urgent need for sustainable site re-development strategies and remediation technologies that are effective, both ...
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 6

 TERMINÉ 

Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders (RUBICON)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

RUBICON will establish a global network for staff exchange of scientists and for research training focussed on connective tissue disorders. It will bring together leading scientific groups from 5 European and 5 non-European countries who will study the molecular and biomechanical factors involved in the pathophysiology of connective tissues, including tendons, cartilage and bone. The ambitious obj ...
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 5

 TERMINÉ 

Targeting epigenetic REPROGRamming of innate immune cells in Atherosclerosis Management and other chronic inflammatory diseases (REPROGRAM)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Up to 70% of cardiovascular events are not prevented by current therapeutic regimens. In search for additional, innovative strategies, immune cells have been recognized as key players contributing to atherosclerotic plaque progression and destabilization. Particularly the role of innate immune cells is of major interest, following the recent paradigm shift that innate immunity, considered to be in ...
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 11

 TERMINÉ 

Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE) (SCIENCE)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE)With more than 17 million deaths worldwide each year, ischemic heart disease (IHD) caused by coronary artery disease is the most common cause of death and a major cause of hospital admissions in industrialised countries. IHD caused over four million deaths in Europe in the year 2012 constituting 47% of all deaths. Today IHD is th ...
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 9

 TERMINÉ 

Absorbing the Potential of Wood Waste in EU Regions and Industrial Bio-based Ecosystems (BioReg)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

BioReg project proposes to create a platform of stakeholders who are able to influence and develop their regions towards bio-based industries and products. Demonstrator case studies have been selected among European regions – Gothenburg, (SE); Karlsruhe, Baden-Wurttember (Ge), Lombardy, Emilia-Romagna (IT), North West England (UK) and Vorarlberg and Syria, Austria. Those have set up renewable wood ...
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 8

 TERMINÉ 

Assessment of forest-carbon sinks and promotion of compensation systems as tools for climate change mitigation  (LIFE FOREST CO2)

Date du début: 2 janv. 2016, Date de fin: 30 déc. 2019,

Background Despite increasing awareness in the land use, land use change and forestry sectors (LULUCF) concerning climate change action, reflected in Decision 529/2013/EU, the emissions and carbon sink effect generated by sustainable forest management (SFM) strategies are not included in the EU’s greenhouse gas (GHG) emissions reduction objectives (40% ...
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 6

 TERMINÉ 

Glaucoma – Advanced, LAbel-free High resolution Automated OCT Diagnostics (GALAHAD)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2019,

The project GALAHAD targets the critical need for better glaucoma diagnostic systems. Glaucoma is an age-related major cause of blindness. The eye disease is characterized by an irreversible damage to the optic nerve head caused by increased intra-ocular pressure. The current screening and basic diagnostics for the disease involve intra-ocular pressure measurement, visual field tests and detection ...
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 10

 TERMINÉ 

Training Network for the Immunotherapy of Cancer (IMMUTRAIN)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,

In the European Union, cancer is the leading cause of death and the overall cancer incidence is still increasing. As a result of expanding efforts to improve cancer outcome, a main paradigm change is occurring in cancer therapy towards individualized medicine. Antibody-based therapies form an integral and constantly growing part of this approach. Antibody-based therapies will strongly influence th ...
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 9