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10 projets européens trouvés

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 TERMINÉ 

Drug Discovery and Delivery NEtwork for ONcology and Eye Therapeutics (3D NEONET)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Severe ocular disorders are affecting the lives of more than 100Mill people world-wide and at least 25% of the population above 70 years of age, a growing demographic group in EU. More than 8 million people lose their lives to cancer every year, making cancer a leading cause of pre-mature mortality in the world. The main hallmarks of severe eye conditions (i.e angiogenesis, inflammation and vascul ...
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 18

 TERMINÉ 

MesopOrous matrices for localiZed pH-triggered releAse of theRapeuTic ions and drugs (MOZART)

Date du début: 1 nov. 2015, Date de fin: 31 oct. 2019,

The concept behind MOZART is to develop a library of inorganic nanomatrices to be used as smart platforms for effective, non-invasive and highly targeted therapies. MOZART will address, as proof of concept, nanomatrices to treat delayed bone healing and non-healing chronic skin wounds, which are both characterised by an inflammation and often infection. Mesoporous therapeutic glasses (MTGs), doped ...
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 11

 TERMINÉ 

Novel Cell Migration Assay Based on Microtissue Technology and Tissue-Specific Matrices (MATRIXASSAY)

Date du début: 1 juin 2015, Date de fin: 31 mai 2019,

Cell migration assays are commonly used to study wound healing, cancer cell invasion, and tissue development. Problems associated with the gap closure assays typically employed are that: (i) the stopper or scratch used to make the migration zone damages the extracellular matrix (ECM), (ii) the migration zone size is limited by the size of the stopper, and (iii) the scratched migration zone shapes ...
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 5

 TERMINÉ 

Drug-Free Antibacterial Hybrid Biopolymers for Medical Applications (HyMedPoly)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

There is a general consensus that biomedical polymers of natural and synthetic origin should and will play a very important role in the development of new therapeutic strategies to treat diseases. Due to resistance of bacteria to drugs, infection has become one of the toughest problems in the medical world as there are hardly any effective antibiotics left in the fight against many pathogens. This ...
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 7

 TERMINÉ 

Novel combination of biopolymers and manufacturing technologies for production of a peripheral nerve implant containing an internal aligned channels array (NEURIMP)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

"Peripheral nerves are basic communication structures guiding motor and sensitive information from CNS to effector or receptor units. Severe nerve injuries include axon bundles section and Schawnn cells destruction, which results in loss of motion control and sensorial perception. After the lesion, cells present in damaged nerves activate spontaneously self-regeneration programs that might facilit ...
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 8

 TERMINÉ 

Antibody-functionalised cardiovascular stents for improved biocompatibility and reduced restenosis (EPICSTENT)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,

An industry-academia collaboration is proposed wherein two industry and three academic partners will establish a lasting, inter-national partnership for transfer of knowledge in biomaterials engineering. The partners have synergistic competences in the medical device sector, and, aided by a schedule of staff secondments and networking events, their relevant niche expertise will be shared and trans ...
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 6

 TERMINÉ 

Reinforced Bioresorbable Biomaterials for Therapeutic Drug Eluting Stents (REBIOSTENT)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,

Active therapeutic biodegradable and biocompatible materials are highly in demand. These are required for the production of medicinal products in a variety of areas including implant technology, tissue engineering, drug delivery and wound healing. Within implant technology such biomaterials can be used for dental, bone and cardiovascular implants. Tailored mechanical properties, biocompatibility a ...
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 14

 TERMINÉ 

Development of Functionalised Cell Seeded Bioartificial Organ for Transplantation in Nerve Repair (NeuroGraft)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2015,

Injuries and degenerative diseases of the central nervous system constitute a bottleneck in medical and surgical practice for which no therapy currently exists. To ensure clinical translation, NeuroGraft is organised in three R&D Work-Packages. NeuroGraft will develop functionalised cell seeded bioartificial organs, specifically spinal cord conduits for transplantation, incorporating a potent immu ...
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 5

 TERMINÉ 

Targeting Hernia Operation Using Sustainable Resources and Green Nanotechnologies. An Integrated Pan-European Approach (Green Nano-Mesh)

Date du début: 1 juin 2011, Date de fin: 31 mai 2015,

Hernia operations are among the most common surgical procedures performed today with over 20 million cases annually worldwide. Hernia incidents are associated with pain and poor quality-of-life for the patient and lead to enormous healthcare costs, exceeding US $48 billion in the US annually. At present, hernia operations rely heavily on non-degradable polypropylene, polytetrafluoroethylene and ny ...
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 11

 TERMINÉ 

Targeting Functional Tendon Regeneration Using a Loaded Biomimetic Scaffold. An Integrated Pan-European Approach (TENDON REGENERATION)

Date du début: 1 sept. 2010, Date de fin: 31 août 2014,

This industry-academia proposal addresses the development of technology which will enable understanding of regeneration of injured or degenerated tendons. Biomimetic fibrous composites will be designed and developed that will mimic the structure of native tendons. The project objectives are to fabricate an optimally stabilised and effectively functionalised three-dimensional collagen-resilin compo ...
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 6