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 TERMINÉ 

SIMVASTATIN AND RIFAXIMIN AS NEW THERAPY FOR PATIENTS WITH DECOMPENSATED CIRRHOSIS (LIVERHOPE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Liver cirrhosis is a very common chronic disease and one of the leading causes of death in European. Moreover, cirrhosis has a marked impact in patients quality of life and represents a major burden for health systems. Treatment of cirrhosis is currently based on symptomatic management of complications and has not changed substantially in the last 20 years. There is an unmet need for therapies tha ...
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 18

 TERMINÉ 

Early-life stressors and LifeCycle health (LIFECYCLE)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Early life is an important window of opportunity to improve health across the full lifecycle. European pregnancy and child cohort studies together offer an unique opportunity to identify a wide range of early life stressors linked with individual biological, developmental and health trajectory variations, and to the onset and evolution of non-communicable diseases. LIFECYCLE will establish the Eur ...
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 19

 TERMINÉ 

REDOX SIGNALING AND METABOLIC STATES IN ANGIOGENESIS IN HEALTH AND DISEASE (rEnDOx)

Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,

Endothelial cells (ECs) exhibit a remarkable and unique plasticity in terms of redox biology and metabolism. They can quickly adapt to oxygen, nitric oxide and metabolic variations. Therefore, EC must be equipped with a selective and unique repertoire of redox and metabolic mechanisms, that play a crucial role to preserve redox balance, and adjust metabolic conditions in both normal and pathologic ...
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 1

 TERMINÉ 

TRANSATLANTIC TRADE AND INVESTMENT PARTNERSHIP-INTERNATIONAL TRAINING NETWORK (TTIP-ITN)

Date du début: 1 avr. 2017, Date de fin: 31 mars 2021,

The EU currently is negotiating a controversial Transatlantic Trade and Investment Partnership (TTIP) agreement with the USA, the main features of which will be the abolition of tariffs, the reduction of non-tariff barriers to trade between the EU and the USA and the introduction of a dispute settlement mechanism. The objective of the proposed TTIP Innovative Training Network (TTIP-ITN) is to fost ...
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 11

 TERMINÉ 

Linking genetic resources, genomes and phenotypes of Solanaceous crops (G2P-SOL)

Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,

G2P-SOL is a research alliance bringing together the major European and International repositories of germplasm with public and private institutions active in genomics, phenotyping and breeding in the four major Solanaceous crops: potato, tomato, pepper and eggplant. These four crops constitute 66% of the value of European horticultural production, and over 65,000 accessions are available within t ...
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 20

 TERMINÉ 

SPIDIA for Personalized Medicine - Standardisation of generic Pre-analytical procedures for In-vitro DIAgnostics for Personalized Medicine (SPIDIA4P)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Molecular in vitro diagnostics and biomedical research have allowed great progress in personalised medicine but further progress is limited by insufficient guidelines for pre-analytical workflow steps (sample collection, preservation, storage, transport, processing etc.) as well as by insufficient quality assurance of diagnostic practice. This allows using compromised patients’ samples with post c ...
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 21

 TERMINÉ 

Advanced materials solutions for next generation high efficiency concentrated solar power (CSP) tower systems (NEXTOWER)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

NEXTOWER shall introduce a set of innovative materials to boost the performance of atmospheric air-based concentrated solar power (CSP) systems to make them commercially viable. In particular, tower systems are appealing for the great environmental compatibility and offer tremendous potential for efficient (electrical and thermal) power generation. Yet, their industrial exploitation has been so fa ...
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 18

 TERMINÉ 

Multi-scale Composite Material Selection Platform with a Seamless Integration of Material Models and Multidisciplinary Design Framework. (COMPOSELECTOR)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

The mission of COMPOSELECTOR is to develop a Business Decision Support System (BDSS), which integrates materials modelling, business tools and databases into a single workflow to support the complex decision process involved in the selection and design of polymer-matrix composites (PMCs). This will be achieved by means of an open integration platform which enables interoperability and information ...
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 11

 TERMINÉ 

A Phase Ib/II study of MEK1/2 inhibitor PD-0325901 or MEK-162 with cMET inhibitor PF-02341066 in RASMT and RASWT (with aberrant c-MET) Colorectal Cancer Patients (MERCURIC)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2020,

Colorectal cancer (CRC) is the 3rd most common cancer in Europe, and with approximately 200,000 deaths per year, it remains the 2nd most common cause of cancer death. More than half of all CRC patients develop distant metastases and have 5-year overall survival (OS) of less than 5% because of ineffective treatments. Increased understanding of cancer biology, coupled with the implementation of “omi ...
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 13

 TERMINÉ 

European Training Network for Continuous Sonication and Microwave Reactors (COSMIC)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2020,

The European chemical industry faces some very serious challenges if it is to retain its competitive position in the global economy. The new industries setting up in Asia and the Near East are based on novel process-intensification concepts, leaving Europe desperately searching for a competitive edge. The transition from batch to continuous micro- and milliflow processing is essential to ensure a ...
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 9

 TERMINÉ 

FORAGE SYSTEMS FOR LESS GHG EMISSION AND MORE SOIL CARBON SINK IN CONTINENTAL AND MEDITERRANEAN AGRICULTURAL AREAS (LIFE+FORAGE4CLIMATE)

Date du début: 1 sept. 2016, Date de fin: 31 août 2020,

Background The agricultural sector and climate change are strongly interlinked. On the one hand, climate change has a significant impact on the quality and quantity of agricultural production and related revenues while, on the other hand, agricultural practices generate considerable amounts of greenhouse gas (GHG) emissions that contribute to global warmi ...
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 5

 TERMINÉ 

Application of omics-based strategies for improved diagnosis and treatment of endocrine hypertension (ENSAT-HT)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,

Arterial hypertension affects up to 45% of the general population and is responsible for 7.1 million deaths per year worldwide. Although a large therapeutic arsenal exists, blood pressure control is sub-optimal in up to two thirds of patients. Yet, even small increments in blood pressure are associated with increased cardiovascular risk, with 62% of cerebrovascular disease and 49% of ischemic hear ...
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 13

 TERMINÉ 

Training network providing cutting-EDGE knowlEDGE on Herpes Virology and Immunology (EDGE)

Date du début: 1 mai 2016, Date de fin: 30 avr. 2020,

Herpesviruses are widely spread, and cause life-long infections. Most individuals carry multiple herpesviruses, which can cause severe diseases, especially in children, immunocompromised individuals, and elderly. There are currently no safe vaccines against herpesvirus infections and current treatments are not satisfactory. With new insights into the molecular basis for diseases caused by immunode ...
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 9

 TERMINÉ 

My Active and Healthy Aging (my-AHA)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

BackgroundWe propose a holistic view of interrelated frailties: cognitive decline, physical frailty, depression and anxiety, social isolation and poor sleep quality, which are a major burden to older adults and social and health care systems. Early detection and intervention are crucial in sustaining active and healthy ageing (AHA) and slowing or reversing further decline.Aims and RelevanceThe mai ...
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 16

 TERMINÉ 

GlucoCEST Imaging of Neoplastic Tumours (GLINT)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Cancer is one of the most devastating diseases the world is currently facing, accounting for 7.6 million deaths in 2008 (WHO). Cancer is usually detected through advanced medical imaging. Early detection is very important as it increases the chances of survival and the potential for full recovery. Further, The high level of sophistication in treating cancer has led to a new unsolved problem, the d ...
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 8

 TERMINÉ 

MIREL - MIning and REasoning with Legal texts (MIREL)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

The management of large repositories of norms, and the semantic access and reasoning to these norms are key challenges in Legal Informatics. The MIREL project will create an international and inter-sectorial network to define a formal framework and to develop tools for MIning and REasoning with Legal texts, with the aim of translating these legal texts into formal representations that can be used ...
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 9

 TERMINÉ 

NEurobehavioural predictiVE and peRsonalised Modelling of depressIve symptoms duriNg primary somatic Diseases with ICT-enabled self-management procedures (NEVERMIND)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Personal health systems for the management of chronic diseases have seen giant leaps in development over recent years. These systems offer vital sign monitoring and therapy delivery at home, focusing on the primary physical disease conditions. However, they do not provide support for early mood assessment or psychological treatment and lack a real-time comprehensive assessment of the patient’s men ...
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 9

 TERMINÉ 

Conflict, Competition, Cooperation and Complexity: Using Evolutionary Game Theory to model realistic populations (FourCmodelling)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

"Real animals and human populations are complex, involving structural relationships depending upon space and time and varied interactions between potentially many individuals. Human societies feature family units, communities, companies and nations. Some animal also have complex societies, such as primate groups and social insect colonies. Single organisms themselves can be thought of as complex e ...
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 5

 TERMINÉ 

In Vivo Spectral Photon Counting CT Molecular Imaging in Cardio- and Neuro-Vascular Diseases (SPCCT)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

The objective of the SPCCT project is to develop and validate a widely accessible, new quantitative and analytical in vivo imaging technology combining Spectral Photon Counting CT and contrast agents, to accurately and early detect, characterize and monitor neurovascular and cardiovascular disease. Spectral Photon Counting Computed Tomography (SPCCT) is a new imaging modality, currently in develop ...
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 12

 TERMINÉ 

Cancer treatment and monitoring through identification of circulating tumour cells and tumour related nucleic acids in blood (CANCER-ID)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Blood-based biomarkers such as Circulating Tumor Cells (CTCs), circulating free tumor DNA (cfDNA) and microRNAs (miRNAs) have the potential to improve the development of personalized medicines for cancer patients. This is of particular importance when biopsies of the primary tumor or metastases are not accessible (e.g. at early disease stages or in minimal residual disease) or possible and the ass ...
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 34

 TERMINÉ 

Improving Diagnosis by Fast Field-Cycling MRI (IDentIFY)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Many diseases are inadequately diagnosed, or not diagnosed early enough by current imaging methods. Examples of unmet clinical needs arise in thromboembolic disease, osteoarthritis, cancer, sarcopenia, and many more areas. Our solution, Fast Field-Cycling (FFC) MRI, can measure quantitative information that is invisible to standard MRI. FFC scanners switch magnetic field while scanning the patient ...
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 9

 TERMINÉ 

Deciphering PI3K biology in health and disease (Phd)

Date du début: 1 nov. 2015, Date de fin: 31 oct. 2019,

The Phosphoinositide 3-kinase (PI3K) pathway is at the core of multiple fundamental biological processes controlling metabolism, protein synthesis, cell growth, survival, and migration. This inevitably leads to the involvement of the PI3K signalling pathway in a number of different diseases, ranging from inflammation and diabetes to cancer, with PI3K pathway alterations present in almost 80% of hu ...
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 11

 TERMINÉ 

European Master of Science of Viticulture and Enology

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,

Objective The aim of the Vinifera EuroMaster programme (European Master of Vine and Wine sciences) is to train motivated people at a high scientific level for leading positions in Grape Production and Wine processing and/or Wine Economics.Course duration Two years (120 ECTS)Brief DescriptionThe curriculum focuses on the perspective of the vineyard to academia. Therefore the consortium receives adv ...
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 6

 TERMINÉ 

GEMex: Cooperation in Geothermal energy research Europe-Mexico for development of Enhanced Geothermal Systems and Superhot Geothermal Systems (GEMex)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2019,

The GEMex project is a complementary effort of a European consortium with a corresponding consortium from Mexico, who submitted an equivalent proposal for cooperation. The joint effort is based on three pillars: 1 – Resource assessment at two unconventional geothermal sites, for EGS development at Acoculco and for a super-hot resource near Los Humeros. This part will focus on understanding the tec ...
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 26

 TERMINÉ 

Skills and competences development of future transportation professionals at all levels (SKILLFUL)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2019,

The Transportation sector employs over 10 million persons in the EU today. At the same time, Transport is a social sector that is rapidly developing, changing and being influenced to the maximum extent by the development of automation, electrification and greening of transport, among others, thus facing problems in staffing its several domains with appropriate and qualified personnel. This fact, m ...
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 21

 TERMINÉ 

Molecularly guided trials with specific treatment strategies in patients with advanced newly molecular defined subtypes of colorectal cancer (MoTriColor) (MoTriColor)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,

Colorectal cancer (CRC) is increasingly being recognized as a heterogeneous disease with distinct molecular subtypes. These subtypes have different biological processes at the basis of their disease and consequently their prognosis and responses to therapy are also different.We have previously developed molecular diagnostic assays using a single platform on routine FFPE tumour biopsies. These assa ...
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 12

 TERMINÉ 

EU-CHINA Lever for IPM Demonstration (EUCLID)

Date du début: 15 sept. 2015, Date de fin: 14 sept. 2019,

More sustainable pest management methods are needed in order to reduce the negative effects of pesticides on human health and the environment. The overall goal of EUCLID is to contribute to secure the production of food for the increasing worldwide population while developing sustainable production approaches to be used in the European and Chinese agriculture.The choice of the crops of interest in ...
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 19

 TERMINÉ 

MASTER IN MATERIAL SCIENCE EXPLORING EUROPEAN LARGE SCALE FACILITIES

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

Objective The objective of the Master Programme in Material Science Exploring European Large Scale Facilities is to prepare skilled scientists in Materials Science together with an advanced knowledge in the use of Large Scale Facilities for the characterization of high-tech materials.Course duration Two years (120 ECTS)Brief DescriptionGlobalisation in modern life has been triggered by the develop ...
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 5

 TERMINÉ 

Spatial containment of Vespa velutina in Italy and establishment of an Early Warning and Rapid Response System (LIFE STOPVESPA)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

Background The Asian predatory wasp (Vespa velutina) is an invasive alien species that poses a serious threat to European biodiversity due to its alimentary habits. The wasp feeds larvae on animal proteins from native wasps, bees, other hymenoptera, diptera and lepidoptera. The species is being controlled in France through the use of baited traps and the ...
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 4

 TERMINÉ 

Migration in Europe:data, models and policies

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

The module “Migration in Europe: data, models and policies” (MIGREU) concerns migrants within the EU. The objective of the course is to enhance students understanding of the complexity and interrelations of migration and the need for deeper knowledge in evaluating appropriate policy choices. -1-The Module starts with the history of the EU migration flows and stock (MIGREU1-history).-2-A discussi ...
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 1

 TERMINÉ 

Juggling Motherhood and Profession

Date du début: 1 nov. 2016, Date de fin: 31 août 2019,

In all Member States, female labour market participation is lower than males’. Data also show a direct correlation between childbearing, care tasks, conciliation and employment: half of the women population exits the work market after child birth. Within such framework, for the more vulnerable and poverty-stricken female segments of the population (e.g. low income, low educated, dealing with socio ...
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 7

 TERMINÉ 

ALK Activation as a target of TRAanslational Science (ALKATRAS): Break free from cancer (ALKATRAS)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

This ETN is embedded into an established international research programme; The European Research Initiative on Anaplastic Lymphoma Kinase (ALK)-related malignancies (ERIA; www.erialcl.net) is an existing and functional network of 13 partners, which will cosset and nurture a cohort of early stage researchers to become confident, competent, independent and well-connected European scientists with exc ...
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 13

 TERMINÉ 

Coordinated Research Infrastructures Building Enduring Life-science services (CORBEL)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

The social and economic challenges of ageing populations and chronic disease can only be met by translation of biomedical discoveries to new, innovative and cost effective treatments. The ESFRI Biological and Medical Research Infrastructures (BMS RI) underpin every step in this process; effectively joining scientific capabilities and shared services will transform the understanding of biological m ...
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 39

 TERMINÉ 

Bioremediation and revegetation to restore the public use of contaminated land (LIFE-BIOREST)

Date du début: 1 juil. 2016, Date de fin: 30 juin 2019,

Background Contamination by hazardous substances is one of the main causes of soil degradation and loss of terrestrial ecosystem services. In the European Union, there are 42 potentially contaminated sites and 5.7 contaminated sites per 10 000 inhabitants. Approximately 340 000 sites require remediation. So far, only 15% of known contaminated sites have b ...
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 7

 TERMINÉ 

Combined Ultrasonic and Enzyme treatment of Lignocellulosic Feedstock as Substrate for Sugar Based Biotechnological Applications (US4GREENCHEM)

Date du début: 1 juil. 2015, Date de fin: 30 juin 2019,

US4GREENCHEM aims to design a biorefinery concept for the complete valorization of lignocellulosic biomass that is energy- and cost- efficient and based solely on green technologies. The concept combines mechanical pretreatment of the substrate with the aid of ultrasound to overcome its recalcitrance and disrupt inhibitors with mild CO2 hemicellulose degradation and with the enzymatic recovery of ...
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 10

 TERMINÉ 

High Integration of Research Monographs in the European Open Science infrastructure (HIRMEOS)

Date du début: 1 janv. 2017, Date de fin: 30 juin 2019,

HIRMEOS will improve five important publishing platforms for the open access monographs in the SSH and enhance their technical capacities and services, rendering technologies and content interoperable and embedding them fully into the European Open Science Cloud. The project focuses on the monograph as a significant mode of scholarly communication in the SSH and ta ...
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 10

 TERMINÉ 

Enhancing Sales Capacity for Agrifood Products in Europe

Date du début: 1 sept. 2016, Date de fin: 30 avr. 2019,

The “Enhancing Sales Capacity for Agri-food Products in Europe” (ESCAPE) project aims at developing and implementing aninnovative blended learning methodology to train food technology students in sales techniques.Most graduates with Master’s degrees in business are highly skilled in sales, but very often lack technical knowledge in food areas.On the other hand, Food Science programmes mostly train ...
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 6

 TERMINÉ 

Elucidating Pathways of Steatohepatitis (EPoS)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

Strongly associated with the epidemics of obesity and type 2 diabetes mellitus (T2DM) that are testing healthcare systems worldwide, Non-Alcoholic Fatty Liver Disease (NAFLD) is an increasingly common cause of advanced liver disease in the aging population of Europe. NAFLD is a spectrum of hepatic fat accumulation (steatosis); steatosis plus inflammation (non-alcoholic steatohepatitis, NASH); fibr ...
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 13

 TERMINÉ 

Lifecourse biological pathways underlying social differences in healthy ageing (LIFEPATH)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

"The dramatic differentials in healthy ageing, quality of life and life expectancy between individuals of different socioeconomic groups, is a major societal challenge facing Europe. The overarching aim of the LIFEPATH project is to understand the determinants of diverging ageing pathways among individuals belonging to different socio-economic groups. This will be achieved via an original study de ...
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 18

 TERMINÉ 

Validation of a personalised medicine tool for Multiple Myeloma that predicts treatment effectiveness in patients (MMpredict)

Date du début: 1 nov. 2016, Date de fin: 30 avr. 2019,

The consortium aims to commercialise the MMpredictor as a personalised medicine tool that predicts the most effective treatment strategy for individual Multiple Myeloma (MM) patients. MM is the second most common form of blood cancer contributing to 15% of all blood cancers and ~1,5% and 2% of all cancer deaths annually in the EU and US, respectively. Patients show a large variability in treatment ...
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 5