Plus de 40 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Perception of Plant Volatiles (PERVOL)
Date du début: 1 mars 2017, Date de fin: 28 févr. 2022,
The capacity to produce and perceive organic chemicals is essential for most cellular organisms. Plant leaves that are attacked by insect herbivores for instance start releasing distinct blends of herbivore-induced plant volatiles, which in turn can be perceived by non-attacked tissues. These tissues then respond more rapidly and more strongly to herbivore attack. One major question that constrain ...
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1
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TERMINÉ
Neuronal circuits for emotions in the ventral CA1 hippocampus (ventralHippocampus)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
A fundamental objective in modern neurosciences is to understand the neural mechanisms of learning and memory in both healthy and pathological conditions. The hippocampus is a high-order cortical brain region important for emotions and cognition. The ventral subdivision of the hippocampus (anterior hippocampus in primates) is mostly involved in anxiety and contextual fear conditioning behaviours. ...
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1
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TERMINÉ
Integrative Mechanisms for Addressing Spatial Justice and Territorial Inequalities in Europe (IMAJINE)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
IMAJINE aims to formulate new integrative policy mechanisms to enable European, national and regional government agencies to more effectively address territorial inequalities within the European Union. It responds to evidence that spatial inequalities within the EU are increasing, contrary to the principle of territorial cohesion embedded as a third dimension of the European Social Model in the Tr ...
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16
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TERMINÉ
Homo Mimeticus: Theory and Criticism (HOM)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2021,
Mimesis is one of the most influential concepts in Western thought. Originally invoked to define humans as the “most imitative” creatures in classical antiquity, mimesis (imitation) has recently been at the centre of theoretical debates in the humanities, social sciences, and the neurosciences concerning the role of “mimicry,” “identification,” “contagion,” and “mirror neurons” in the formation of ...
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1
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TERMINÉ
Dissection of a cortical microcircuit for the processing of pain affect (CorPain)
Date du début: 1 sept. 2016, Date de fin: 31 août 2021,
It is a fundamental but still elusive question how nociceptive processing is performed in neuronal networks in the cortex for the conscious experience of pain.The objective of this project is to identify and characterize the cortical microcircuits in the anterior cingulate cortex (ACC) that are involved in pain processing with cellular resolution. The ACC is essential for evaluating the emotional/ ...
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1
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TERMINÉ
Characterizing Adaptation and Migration Events with Modern and Ancient Genomes (CAMERA)
Date du début: 1 août 2016, Date de fin: 31 juil. 2021,
BACKGROUND Ancient DNA research has recently entered the genomics era. Performing “ancient population genomics” is now technically possible. Utilizing the temporal aspect of this new data, we can address fundamental evolutionary questions such as the amount of selection acting on the genome or the mode and tempo of the colonization of the world. AIMS The overall goal of the proposed research is to ...
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1
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TERMINÉ
Synthetic viability of homologous recombination-deficient cancers (SYNVIA)
Date du début: 1 juil. 2016, Date de fin: 30 juin 2021,
Although various effective anti-cancer drug treatments have become available over the last decades, drug resistance remains the major cause of death of cancer patients. Striking examples are patients with tumors that are defective in DNA repair by homologous recombination (HR). Despite initial responses to cancer therapy, resistance of primary or disseminated tumors eventually emerges, which minim ...
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1
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TERMINÉ
Mechanisms of RNA-guided genome editing in eukaryotes (G-EDIT)
Date du début: 1 mai 2016, Date de fin: 30 avr. 2021,
The goal of this project is to contribute to our understanding of RNA-mediated epigenetic mechanisms of genome regulation in eukaryotes. Ciliated protozoa offer a fantastic opportunity to investigate the complex process of trans-generational programming of chromosomal rearrangements, which is thought to serve as a form of immune defense against invasive DNA. Developmental processes in ciliates inc ...
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1
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TERMINÉ
Soil Care for profitable and sustainable crop production in Europe (SOILCARE)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,
European crop production is to remain competitive while reducing environmental impacts, requiring development and uptake of effective soil improvingcropping systems. The overall aim of SOILCARE is to identify and evaluate promising soil-improving cropping systems and agronomictechniques increasing profitability and sustainability across scales in Europe. A trans-disciplinary approach will be used ...
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29
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TERMINÉ
Molecular Tools for Nucleic Acid Manipulation for Biological Intervention (MMBio)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
MMbio will bridge the classically separate disciplines of Chemistry and Biology by assembling leading experts from academia and non-academic partners (industry, technology transfer & science communication) to bring about systems designed to interfere therapeutically with gene expression in living cells. Expertise in nucleic acid synthesis, its molecular recognition and chemical reactivity is combi ...
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13
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TERMINÉ
4D analysis of heart development and regeneration using advanced light microscopy (4DHeart)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
Cardiovascular (CV) disease is a main cause of death worldwide. During adulthood, ischemic heart disease leads to heart failure and perinatally, congenital heart defects are found in over 20% of deaths. Moreover, genetic or epigenetic factors altering development can have an impact much later in life. These facts underscore the need of a better understanding of the genetic and environmental factor ...
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7
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TERMINÉ
Personalised Risk assessment in febrile illness to Optimise Real-life Management across the European Union (PERFORM)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
The management of febrile patients is one of the most common and important problems facing healthcare providers. Distinction between bacterial infections and trivial viral infection on clinical grounds is unreliable, and as a result innumerable patients worldwide undergo hospitalization, invasive investigation and are treated with antibiotics for presumed bacterial infection when, in fact, they ar ...
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19
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TERMINÉ
Photoacoustic/Ultrasound Mammoscopy for evaluating screening-detected abnormalities in the breast (PAMMOTH)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
X-ray mammography is the mainstay of breast cancer screening programs. It is estimated that between 20 - 50% of abnormal screening mammograms will prove to be negative. The paradigm in diagnosis is to establish whether a lesion is benign or malignant. All the imaging techniques conventionally used today – diagnostic x-ray, ultrasonography and magnetic resonance imaging have many limitations, leadi ...
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9
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TERMINÉ
European HIV Vaccine Alliance (EHVA): a EU platform for the discovery and evaluation of novel prophylactic and therapeutic vaccine candidates (EHVA)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,
Many HIV vaccine concepts and several efficacy trials have been conducted in the prophylactic and therapeutic fields with limited success. There is an urgent need to develop better vaccines and tools predictive of immunogenicity and of correlates of protection at early stage of vaccine development to mitigate the risks of failure. To address these complex and challenging scientific issues, the Eur ...
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43
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TERMINÉ
High Performance Soft-tissue Navigation (HiPerNav)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,
Primary liver cancer, which consists predominantly of hepatocellular carcinoma (HCC), is the fifth most common cancer worldwide and the third most common cause of cancer mortality. A successful surgical resection of HCC requires complete removal of the tumour while sparing as much healthy tissue as possible. Due to technical and clinical difficulties relatively low percentage of patients are eligi ...
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10
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TERMINÉ
Deciphering the greenhouse gas record in deepest ice using continuous sublimation extraction / laser spectrometry (deepSLice)
Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,
The recent anthropogenic global warming makes a detailed understanding of coupling processes between climate and biogeochemical cycles of pressing importance. The atmospheric archive of air bubbles enclosed in polar ice cores provides the only direct record of greenhouse gas changes in the past, and the key to understanding the related changes in biogeochemical cycles and climate/greenhouse gas fe ...
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1
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TERMINÉ
Interactive Soil Quality Assessment in Europe and China for Agricultural Productivity and Environmental Resilience (iSQAPER)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
Knowledge regarding the complex interplay between agricultural land use and management and soil quality and function is fragmented and incomplete, in particular with regard to underlying principles and regulating mechanisms. The main aim of iSQAPER is to develop an interactive soil quality assessment tool (SQAPP) for agricultural land users that integrates newly derived process understanding and a ...
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25
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TERMINÉ
OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly (OPERAM)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
Most older adults have multiple chronic diseases (multimorbidity) and multiple medications (polypharmacy). However, multimorbid patients are often excluded from clinical trials and most guidelines address diseases in isolation. Inappropriate drug prescription and poor drug compliance are common and contribute to up to 30% of hospital admissions. OPERAM investigators developed STOPP/START criteria ...
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9
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TERMINÉ
Alzheimer Disease - gut connection (AD-gut)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2020,
Alzheimer’s disease (AD) is the leading cause of dementia in the Western world and to date no cure nor any preventive strategy are available for this neurodegenerative disorder. Bacterial 16S rRNA sequencing from fecal samples revealed a remarkable shift in the gut microbiota of conventionally-raised AD mice compared to healthy, wild-type mice. Based on these findings, we generated germ-free Alzhe ...
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6
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TERMINÉ
Social Innovation in Marginalised Rural Areas (SIMRA)
Date du début: 1 avr. 2016, Date de fin: 31 mars 2020,
SIMRA seeks to advance understanding of social innovation (SI) and innovative governance in agriculture, forestry and rural development (RD), and how to boost them, particularly in marginalised rural areas across Europe, with a focus on the Mediterranean region (including non-EU) where there is limited evidence of outcomes and supporting conditions. These objectives will be achieved by: 1. Develop ...
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26
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TERMINÉ
Exploiting Synergistic Properties of Mesoionic Carbene Complexes: Teaching Rusty Metals Challenging Catalysis (synMICs)
Date du début: 1 févr. 2015, Date de fin: 31 janv. 2020,
The non-innocence of specific ligands in transition metal complexes is well-documented. For example, mesoionic carbenes engage in bond activation processes via reversible hydrogen capture. Such cooperativity between the metal center and the ligand flattens the potential energy surface of a catalytic reaction and hence rises the competence of the catalyst, thus entailing higher turnover numbers as ...
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2
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TERMINÉ
Big Data in Chemistry (BIGCHEM)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
The advent of the big data era in chemistry and the life sciences requires the development of new computational analysis methods, which are not only of scientific, but also economic relevance. Currently, the international data market already grows six times faster than the entire IT sector, and growth rates further increase. Achieving and sustaining a leadership positions in the big data arena rep ...
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9
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TERMINÉ
Non-Noble Metal Catalysis - NoNoMeCat (NoNoMeCat)
Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,
Transition metal catalysts are formidable tools towards greener chemistry, allowing for low-waste, energy-efficient, and selective reactions. However, the noble metals (Ru, Os, Rh, Ir, Pd, Pt) that are currently most common in homogeneous catalysts suffer from high toxicity and environmental impact in addition to their scarcity and ensuing high cost. First-row metals (Mn, Fe, Co, Ni, Cu) are emerg ...
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9
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TERMINÉ
Risk assessment of plaque rupture and future cardiovascular events (CVENT) by multi-spectral photoacoustic imaging (CVENT)
Date du début: 1 nov. 2016, Date de fin: 31 oct. 2019,
Cardiovascular disease (CVD), more specifically, vulnerable plaque rupture, remains the major cause of death for people at middle age. The CVENT consortium will revolutionize screening, diagnosis and monitoring of CVD by means of a compact photoacoustic imaging (PAI) system for vulnerable plaque imaging.In the carotid arteries feeding the brain, vulnerable plaque rupture initiates cerebrovascular ...
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10
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TERMINÉ
Clinical evaluation of carbons of controlled porosity as a new therapeutic for the treatment of liver cirrhosis and non-alcoholic fatty liver disease. (CARBALIVE)
Date du début: 1 mai 2015, Date de fin: 31 oct. 2019,
Chronic liver disease affects about 29-million Europeans accounting for about 170,000 deaths at a cost of around €15.8bn. This chronic non-communicable disease is increasing at an alarming rate due to increasing European obesity, alcohol use and ageing. The three main causes of the disease; alcohol, fatty liver and viral hepatitis are amenable to prevention and treatment. Gut-derived endotoxins an ...
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15
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TERMINÉ
Beyond EPICA - Oldest Ice (BE-OI)
Date du début: 1 oct. 2016, Date de fin: 30 sept. 2019,
To better constrain the response of Earth’s climate system to continuing emissions, it is essential to turn to the past. A key advance would be to understand the transition in Earth’s climate response to changes in orbital forcing during the 'mid-Pleistocene transition' (900 to 1200 thousand years ago) and in particular the role of greenhouse gases. Unravelling such key linkages between the carbon ...
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14
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TERMINÉ
Integrating Technology into Mental Health Care Delivery in Europe (ICare)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
The evidence base of Internet-based interventions in the prevention and treatment of mental health conditions has rapidly grown in the past decade. Yet many European countries (e.g., Germany, Austria, Switzerland, Great Britain, The Netherlands, Spain) have not implemented these promising approaches into health systems. Individuals with risk conditions or distinct mental health problems interested ...
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13
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TERMINÉ
Brain barriers training (BtRAIN)
Date du début: 1 sept. 2015, Date de fin: 31 août 2019,
The brain barriers function to protect the central nervous system (CNS) from neurotoxic compounds. By the same traits they unfortunately block delivery of drugs to the CNS thus hindering proper diagnosis and effective treatment of neurological disorders including Alzheimer’s disease and multiple sclerosis. The unusual complexity of the brain barriers has severely hampered progress in the market of ...
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11
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TERMINÉ
Active Mechanisms of Cell Selection: From Cell Competition to Cell Fitness (CELLFITNESS)
Date du début: 1 juin 2014, Date de fin: 31 mai 2019,
"The molecular mechanisms that mediate cell competition, cell fitness and cell selection is gaining interest. With innovative approaches, molecules and ground-breaking hypothesis, this field of research can help understand several biological processes such as development, cancer and tissue degeneration. The project has 3 clear and ambitious objectives: 1. We propose to identify all the key genes m ...
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1
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TERMINÉ
Cement-based materials, properties, evolution, barrier functions (Cebama)
Date du début: 1 juin 2015, Date de fin: 31 mai 2019,
The HORIZON 2020 EURATOM Collaborative Project “Cement-based materials, properties, evolution, barrier functions (Cebama)” is developed with the overall objective to support implementation of geological disposal of nuclear waste by improving the knowledge base for the Safety Case. Cement-based materials are highly relevant in this context, being used as waste forms, liners and structural component ...
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28
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TERMINÉ
A EUropean study on effectiveness and sustainability of current Cardiac Rehabilitation programmes in the Elderly (EU-CaRE)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,
Cardiovascular diseases (CVD) cause over 4 million deaths in Europe each year and mass disability: within the coming decades the disability-adjusted life years (DALYs) estimate is expected to rise from a loss of 85 million DALYs in 1990 to a loss of 150 million DALYs globally in 2020. Moreover, patient numbers are expected to rise rapidly in the next decades, due to an ageing society such that th ...
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11
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TERMINÉ
Climate Security with Local Authorities (CLISEL) From insecurity takers to security makers: mobilizing local authorities to secure the EU against the impacts of climate change in Third Countries (CLISEL)
Date du début: 1 mai 2016, Date de fin: 30 avr. 2019,
CLISEL proposes an innovative approach to the question of how Europe can be secured from the impacts of climate change in Third Countries. Most academic and policy initiatives to date have focused on the direct security impacts of climate change in Third Countries and/or on the indirect impacts on international security (e.g. concerning regional economic or political stability). While those initia ...
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6
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TERMINÉ
Syntax Meets Semantics: Methods, Interactions, and Connections in Substructural logics. (SYSMICS)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2019,
Substructural logics are formal reasoning systems that refine classical logic by weakening the structural rules in Gentzen sequent calculus.While classical logic generally formalises the notion of truth, substructural logics allow to handle notions such as resources, vagueness, meaning, and language syntax, motivated by studies in computer science, epistemology, economy, and linguistics. Moreover, ...
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13
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TERMINÉ
All Solid-State Super-Twinning Photon Microscope (SUPERTWIN)
Date du début: 1 mars 2016, Date de fin: 28 févr. 2019,
The goal of the project is to develop the technology foundation for an advanced optical microscope imaging at a resolution beyond the Rayleigh limit, which is set by the photon wavelength. The proposed microscope technique is based on super-twinning photon states (N-partite entangled states) with the de Broglie wavelength equal to a fraction of the photon wavelength. Such microscopy technique will ...
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9
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TERMINÉ
Strengthening Animal Production and Health through the Immune Response (SAPHIR)
Date du début: 1 mars 2015, Date de fin: 28 févr. 2019,
SAPHIR aims to develop vaccine strategies effective against endemic pathogens responsible for high economic losses in livestock in order to strengthen the profitability of food animal systems, improve animal welfare and reduce xenobiotic usage in farming with a One Health perspective. SAPHIR will bring novel vaccine strategies to the market i) at short term, with several promising vaccines brought ...
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22
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TERMINÉ
Novel insights into cardiac regeneration through studies in the zebrafish (zebraHeart)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
Myocardial infarction (MI) leads to cardiomyocyte death and accumulation of myofibroblasts (MFs) at the site of injury, which produce large amounts of extracellular matrix (ECM), generating a scar. Initially, cardiac fibrosis protects from ventricular wall rupture, but subsequent myocardial remodelling causes heart failure, representing a leading cause of death in Europe. While MFs play a central ...
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2
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TERMINÉ
Classical and Atomic Quantum Simulation of Gauge Theories in Particle and Condensed Matter Physics (AtomicGaugeSimulator)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,
Gauge theories play a central role in particle and condensed matter physics. Heavy-ion collisions explore the strong dynamics of quarks and gluons, which also governs the deep interior of neutron stars, while strongly correlated electrons determine the physics of high-temperature superconductors and spin liquids. Numerical simulations of such systems are often hindered by sign problems. In quantum ...
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1
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TERMINÉ
The Effects of Media News about Immigrants on Majority’s Attitudes and Behaviors towards Immigrants (IMMIGRANTS)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2018,
The interdisciplinary IMMIGRANTS project aims at a better understanding of how media influence majority’s attitudes and behaviors towards immigrants – a socially pressing issue connected to rapid expansion of immigration in Europe. In the project, I will focus on different aspects of media news – their valence, labels used for immigrants’ ethnicity and pictures of immigrants accompanying media art ...
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1
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TERMINÉ
International Fellowship Program on Integrative Kidney Physiology and Pathophysiology (IKPP2)
Date du début: 1 janv. 2014, Date de fin: 31 déc. 2018,
"IKPP is a postdoctoral program established in June 2010 with the help of European funding under the FP7 COFUND scheme. IKPP is associated with the interuniversitary educational program of a Swiss National Centre of Competence in Research, ""Kidney Control of Homeostasis – Kidney.CH"". The educational program of IKPP within Kidney.CH strengthens integrative thinking and awareness for kidney-centre ...
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1
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TERMINÉ
Preventing and Remediating degradation of soils in Europe through Land Care (RECARE)
Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,
Although there is a large body of knowledge available on soil threats in Europe, this knowledge is fragmented and incomplete, in particular regarding the complexity and functioning of soil systems and their interaction with human activities. The main aim of RECARE is to develop effective prevention, remediation and restoration measures using an innovative trans-disciplinary approach, actively inte ...
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