7 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Synthetic Biology for the production of functional peptides (SYNPEPTIDE)
Date du début: 1 sept. 2013, Date de fin: 31 août 2017,
"Peptides are among the most versatile natural products that nature provides to cater for a broad set of biotechnological applications ranging from antibiotics to personal hygiene. Their diversity comes from a broad variety of posttranslational modifications that is used to provide additional functionality beyond to what is possible with the classic proteinogenic set of 20 amino acids. In SYNPEPTI ...
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7
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TERMINÉ
Synthetic biology – Engaging with New and Emerging Science and Technology in Responsible Governance of the Science and Society Relationship (SYN-ENERGENE)
Date du début: 1 juil. 2013, Date de fin: 30 juin 2017,
Synthetic biology (SynBio) offers huge potential for applications in energy, health and the environment. It also brings with it various challenges such as regulatory issues of biosafety, biosecurity and intellectual property rights, as well as potential environmental and socio-economic risks in developing countries. As yet, however, there is scant public knowledge about the technology. It is thus ...
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29
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TERMINÉ
Synthetic biology approach for the design of new-to-nature peptide-based antibiotic molecules (PTM-FLEX)
Date du début: 15 avr. 2014, Date de fin: 14 avr. 2016,
The rise of pathogenic bacteria that are resistant against a variety of antibiotic treatment emphasizes the need for novel active molecules. One promising novel class of active molecules is genetically encoded and ribosomally synthesized peptides, as they offer the potential to employ directed evolution approaches across a huge sequence space directly on an active substance in order to engineer no ...
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1
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TERMINÉ
Code-engineered new-to-nature microbial cell factories for novel and safety enhanced bio-production (METACODE)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,
The concept of METACODE is to preform genetic code engineering in microbial strains with parallel recruitment of novel bio-orthogonal chemistries for mass production of desired protein/peptide based products. In combination with computational and classical chemical synthetic approaches as well as chemo-informatics, enzyme guided evolution, synthetic metabolism, and directed evolution of microbial ...
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8
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TERMINÉ
Standarization and orthogonalization of the gene expression flow for robust engineering of NTN (new-to-nature) biological properties (ST-FLOW)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,
The ST-FLOW Project merges the efforts of 14 leading European research groups for developing material and computational standards that enable the forward-design of prokaryotic systems with a degree of robustness and predictability that is not possible with customary Genetic Engineering. The central issue at stake is the identification and implementation of rules that allow the conversion of given ...
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15
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TERMINÉ
Paving the Way for Future Emerging DNA-based Technologies: Computer-Aided Design and Manufacturing of DNA libraries (CADMAD)
Date du début: 1 févr. 2011, Date de fin: 31 oct. 2014,
CADMAD aims to make a foundational breakthrough in the way computers and computer-aided design and manufacturing is employed in DNA-based research and development, making a radically new use of information technologies in biology and biotechnology.Biology and biotechnology research involves "DNA programming", which is akin to computer programming. Researchers modify and combine DNA of interest in ...
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12
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TERMINÉ
Two-Step-Strategy towards an Orthogonal Bio-System (MazProTec)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2014,
The integration of orthogonality is a crucial research strategy in the rational design of biological systems for novel applications. In order to produce such highly predictable orthogonal systems, we propose to employ cell-free systems of highly engineered composition generated from living cells, which are complex enough to reproduce the major synthetic capabilities of living cells - such as the s ...
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