10 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Adoptive engineered T cell Trials to Achieve Cancer Killing (ATTACK)
Date du début: 1 déc. 2012, Date de fin: 30 nov. 2017,
The aim of this research is to exploit technology for nucleic acid delivery through the clinical testing of adoptive engineered T cells to treat cancer. Recent innovative developments in cancer gene-immunotherapy have led to very encouraging early clinical results. However, the use of engineered T cells is a challenging and complex field with further development and more proof-of-principle trials ...
Voir le projet
16
Participants partenaires
TERMINÉ
Stem-cell based therapy for kidney repair (STELLAR)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,
Chronic kidney disease (CKD) affects 8% of the European population and ultimately results in renal failure due to progressive fibrosis. CDK carries a high mortality risk and the number of affected people rises, increasing the demand on renal replacement therapies while the number of available donor organs stays stable.The STELLAR consortium proposes to develop an alternative to renal replacement ...
Voir le projet
15
Participants partenaires
TERMINÉ
Initial Training Network for Neurogical disorders orchestrated by cytoKines (NEUROKINE)
Date du début: 1 janv. 2013, Date de fin: 31 mai 2017,
Neuroinflammatory disease, in particular multiple sclerosis affects more than 700.000 people within Europe alone. European countries are at the forefront of neuroimmunological research and students in medicine and biology are greatly attracted by the field. Neuroimmunology research further impacts our understanding of the ethiopathology of other CNS-disorders including Alzheimer’s Dementia and Mor ...
Voir le projet
13
Participants partenaires
TERMINÉ
Natural Killer Cell-Based Anti-Cancer Immunotherapies: Research training in molecular medicine and biotechnology business (NATURIMMUN)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
"In the research part we will deal with the basic principles of the innate immune defense used to control tumors and viral infections with a focus on NK and NK/T cells, including analysis of NK receptor genomics/epigenetics, gene polymorphisms/disease linkage, differentiation of hitherto unrecognized NK cell subpopulations and novel ligands for NK receptors exposed by tumor and/or virally infected ...
Voir le projet
12
Participants partenaires
TERMINÉ
MARie CuRIe AGEing Network (MARRIAGE)
Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,
"One of achievements of developed societies has been the remarkable extension of human lifespan. In the upcoming decades the number of Europeans with advanced age will increase dramatically. It is evident that age-associated diseases will become much more prevalent. This poses challenges for society but also opportunities for commercial enterprises that develop strategies to combat deleterious con ...
Voir le projet
11
Participants partenaires
TERMINÉ
Advanced Cell-based Therapies for the treatment of Primary ImmunoDeficiency (CELL-PID)
Date du début: 1 nov. 2010, Date de fin: 30 avr. 2016,
Primary immune deficiencies (PID) are inherited disorders of the adaptive and innate immune system marked by severe infections, autoimmunity and high risk of cancer. Treatment entails hematopoietic stem cell (HSC) transplantation from allogeneic donors, however in the absence of an HLA compatible donor, HSCT outcome is limited by delayed or suboptimal reconstitution and complications. SCID-X1 and ...
Voir le projet
20
Participants partenaires
TERMINÉ
Stromal Cell- Immune Cell Interactions in Health and Disease (STROMA)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
STROMA is an Initial Training Network promoting the study of stromal cell – immune system interactions during stroma development and function in health and disease. In STROMA we have bought together world leading experts from academia and industry in Europe to address the key scientific questions in this emerging field. STROMA will promote the training of three Experienced Researchers (ER) and s ...
Voir le projet
12
Participants partenaires
TERMINÉ
Dopaminergic Neurons for Cell Therapy in Parkinson's Disease (DOPANEW)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,
Replacement of lost dopaminergic neurons by neural transplantation with embryonic nigral tissue is a most promising approach to the treatment of Parkinson’s disease. However, the limited availability of human embryonic dopaminergic neurons makes the search for alternative sources of transplantable neurons a priority. Based on an existing collaboration, a French academic research group with experti ...
Voir le projet
2
Participants partenaires
TERMINÉ
Recruitment and activation of brown adipocytes as preventive and curative therapy for type 2 diabetes (DIABAT)
Date du début: 1 oct. 2011, Date de fin: 30 sept. 2015,
"The DIABAT project will employ knowledge of the function, dysfunction and physiological regulation of brown adipocytes to develop innovative therapeutic and preventive strategies for type 2 diabetes. Brown adipose tissue (BAT) is currently a worldwide recognized target to combat obesity and diabetes due to last years re-discovery of functional BAT in adult humans by several of the members of the ...
Voir le projet
22
Participants partenaires
TERMINÉ
EUROCANCER STEMCELL TRAINING NETWORK (EuroCSCTraining)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,
The recent identification of tumor initiating (TIC) or cancer stem cells (CSC) has opened a new area of research for scientists interested in cancer. Understanding the biology of cancer stem cells has already unraveled pathways and potential targets. However, accumulating data has underscored the complexity of the CSC research area and prompts hence the need for well-structured networks to provid ...
Voir le projet