6 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
Hepatic and Cardiac Toxicity Systems modelling (HECATOS)
Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,
HeCaToS aims at developing integrative in silico tools for predicting human liver and heart toxicity. The objective is to develop an integrated modeling framework, by combining advances in computational chemistry and systems toxicology, for modelling toxic perturbations in liver and heart across multiple scales. This framework will include vertical integrations of representations from drug(metabol ...
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14
Participants partenaires
TERMINÉ
Learning from integrated eCare practice and promoting deployment in European regions (Beyond Silos)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,
Description
BeyondSilos enables delivery of integrated care to older Europeans to support them to live independently within the community by providing the ICT tools necessary to join up care pathways across organisations, in particular between social and health service providers. A key area of integration is providing cross-sectoral teams wi ...
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16
Participants partenaires
TERMINÉ
Mechanisms of cell dysfunction by aggregation dynamics of polyQ-containing proteins (MechAggrenamics)
Date du début: 1 nov. 2012, Date de fin: 31 oct. 2016,
Protein aggregation is a hallmark of several ageing-related neurodegenerative diseases, such as Huntington’s disease (HD), Alzheimer’s disease and prion-mediated diseases. Different cellular pathways influence the rate of aggregation, and clearance of intermediate protein species and aggregates in the cell (for example, autophagy or proteasomal degradation). Many signalling pathways regulate these ...
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1
Participant partenaire
TERMINÉ
EUROPEAN NETWORK for CANCER research in CHILDREN and ADOLESCENTS (ENCCA)
Date du début: 1 janv. 2011, Date de fin: 31 déc. 2015,
"ENCCA aims to establish a durable, European Virtual Institute clinical and translational research in childhood and adolescent cancers that will define and implement an integrated research strategy and will facilitate the necessary investigator-driven clinical trials to introduce the new generation of biologically targeted drugs into standard of care for children and adolescents with cancer. This ...
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34
Participants partenaires
TERMINÉ
Realizing the European Network in Biodosimetry (RENEB)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
Creating a sustainable network in biological dosimetry that involves a large number of experienced laboratories throughout the EU will significantly improve the accident and emergency response capabilities in case of a large-scale radiological emergency. A well organised cooperated action involving EU laboratories will offer the only chance for a fast and trustworthy dose assessment urgently neede ...
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28
Participants partenaires
TERMINÉ
Innovative strategies to generate human hepatocytes for treatment of metabolic Liver diseases: Tools for personalized cell therapy (InnovaLiv)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2014,
Transplantation of donor hepatocytes has become an alternative to liver transplantation for the treatment of liver diseases. However, in addition to the complication imposed by severe shortage of donor livers, adult hepatocytes cannot be expanded in vitro. Autologous transplantation of genetically corrected hepatocytes represents another strategy as it circumvents the need for immunosuppression bu ...
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