8 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
European Sudden Cardiac Arrest network: towards Prevention, Education and NEw Treatment (ESCAPE-NET)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
Sudden cardiac arrest (SCA) causes ~20% of all deaths in Europe. SCA is lethal within minutes if left untreated and survival rates are presently only 5-20%. Therefore, there is a large medical need to improve SCA prevention and treatment. Designing effective individualized prevention and treatment strategies requires knowledge on genetic and environmental risk factors. So far, these efforts have b ...
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17
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TERMINÉ
Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’: A Randomized Controlled Multicentre Trial (PAPA-ARTIS)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,
Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time but continue to increase in diameter before they eventually rupture. Left untreated, the patients’ prognosis is dismal, since the internal bleeding of the rupture brings about sudden death. Although successful treatment cures the disease, the risky procedures can result in ...
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26
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TERMINÉ
A multi-center randomized, placebo-controlled trial of mirabegron, a new beta3-adrenergic receptor agonist on left ventricular mass and diastolic function in patients with structural heart disease (BETA3_LVH)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,
Patients with cardiovascular risk factors, e.g. hypertension and obesity are at risk of developing heart failure with preserved ejection fraction (HFpEF), a highly prevalent disease in the elderly, mostly women population. There is currently no specific, defined treatment for HFpEF, beyond control of risk factors. Activation of cardiac and vascular Beta3-adrenergic receptors (B3AR) represents a ne ...
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15
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TERMINÉ
Characterizing Atrial fibrillation by Translating its Causes into Health Modifiers in the Elderly (CATCH ME)
Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,
Atrial fibrillation (AF) is the most common cardiac arrhythmia, with a prevalence of 1.5-2% in European populations. By being a major cause of stroke, dementia, heart failure, and premature death, AF is a major threat to healthy ageing. Despite increasing knowledge on the diverse mechanisms that cause the AF substrate in individual patients, current strategies for prevention and therapy of AF rema ...
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9
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TERMINÉ
Methods for Health Technology Assessment of Medical Devices: a European Perspective (MEDTECHTA)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,
Health Technology Assessment (HTA) is widely accepted as a multidisciplinary approach studying the clinical, economic, social and ethical implications of development, diffusion and use of health technologies and its role in policy making is increasingly established in EU countries. However, the currently adopted methodological framework for HTA doesn’t fully encounter the challenges rising from in ...
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7
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TERMINÉ
A survey of the European cardiovascular research landscape and recommendations for future research strategy (CardioScape)
Date du début: 1 nov. 2012, Date de fin: 30 sept. 2014,
CARDIOSCAPE will aim to outline the current CVD research and innovation landscape across Europe towards establishing the extent of duplication across national research programmes and the existence of gaps that reduce opportunities for innovation.It will build on and develop an existing comprehensive partner network, seeking to include actors covering the full innovation cycle, to help identify the ...
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2
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TERMINÉ
Evaluation of Integrated Cardiac Imaging for the Detection and Characterization of Ischemic Heart Disease (EVINCI-study)
Date du début: 1 janv. 2009, Date de fin: 30 juin 2012,
The main purpose of the EVINCI-study is to test the impact of combined “anatomo-functional” non invasive cardiac imaging for detection and characterization of Ischemic Heart Disease (IHD). The EVINCI-study is a prospective clinical European multicenter trial performed in a cohort of 700 patients with suspected IHD. Patients with intermediate pre-test probability will undergo clinical and biohumora ...
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22
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TERMINÉ
Provision of the latest information through the development of a highly targeted educational web site, designed to meet key clinical needs, will ensure that the areas of greatest educational need in cardiovascular medicine are addressed. New and more effective interventions to combat cardiovascular disease are being developed at a rapid rate, which means that there is an ever increasing need for ...
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