Rechercher des projets européens

Plus de 40 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

Healthy minds from 0-100 years: Optimising the use of European brain imaging cohorts (Lifebrain)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

...tal health measures for extensively broader cohorts, exceeding 40.000 examinations in total. By linking these data, also to additional databases and biobanks, including birth registries, national and regional archives, and by enriching them with new online data collection and novel measures, we will address risk and protective factors of brain, cognitive and mental health throughout the lifespan. ...
Voir le projet

 16

 TERMINÉ 

European Human Biomonitoring Initiative (HBM4EU)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The overarching goal of the European Human Biomonitoring Initiative (HBM4EU) is to generate knowledge to inform the safe management of chemicals and so protect human health. We will use human biomonitoring to understand human exposure to chemicals and resulting health impacts and will communicate with policy makers to ensure that our results are exploited in the design of new chemicals policies an ...
Voir le projet

 43

 TERMINÉ 

European Sudden Cardiac Arrest network: towards Prevention, Education and NEw Treatment (ESCAPE-NET)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Sudden cardiac arrest (SCA) causes ~20% of all deaths in Europe. SCA is lethal within minutes if left untreated and survival rates are presently only 5-20%. Therefore, there is a large medical need to improve SCA prevention and treatment. Designing effective individualized prevention and treatment strategies requires knowledge on genetic and environmental risk factors. So far, these efforts have b ...
Voir le projet

 17

 TERMINÉ 

Reaching the effects of gastric bypass on diabetes and obesity without surgery (BYPASSWITHOUTSURGERY)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

...ational scope, all elements involved in these responses will be addressed in this project, from detailed analysis of food items responsible for hormone secretion, to identification of the responsible regions of the gut, and to the molecular mechanisms leading to hypersecretion. Novel approaches for studies of human gut hormone secreting cells, including specific expression analysis, are combined w ...
Voir le projet

 2

 TERMINÉ 

Multiple manifestations of genetic and non-genetic factors in Multiple Sclerosis disentangled with a multi-omics approach to accelerate personalised medicine (MultipleMS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

The complex interactions between genetic and non-genetic factors produce heterogeneities in patients as reflected in the diversity of pathophysiology, clinical manifestations, response to therapies, disease development and progression. Yet, the full potential of personalized medicine entails biomarker-guided delivery of efficient therapies in stratified patient populations.MultipleMS will therefor ...
Voir le projet

 25

 TERMINÉ 

Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’: A Randomized Controlled Multicentre Trial (PAPA-ARTIS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time but continue to increase in diameter before they eventually rupture. Left untreated, the patients’ prognosis is dismal, since the internal bleeding of the rupture brings about sudden death. Although successful treatment cures the disease, the risky procedures can result in ...
Voir le projet

 26

 TERMINÉ 

Clinical development and proof of principle testing of new regenerative VEGF-D therapy for cost-effective treatment of refractory anginaA phase II randomized, double-blinded, placebo-controlled study (ReGenHeart)

Date du début: 1 janv. 2017, Date de fin: 30 juin 2021,

Chronic angina pectoris is a debilitating chronic disease, a subgroup of these patients suffers from refractory angina which unfortunately can’t be controlled by medical therapy (angioplasty or surgery). Refractory angina is a substantial burden on the individual and healthcare system, in Europe there are 100,000 new cases per year, annual mortality of these patients is relatively low (
Voir le projet

 10

 TERMINÉ 

RECAP: Research on European Children and Adults born Preterm (RECAP)

Date du début: 1 janv. 2017, Date de fin: 31 mars 2021,

The project’s overall aim is to improve the health, development and quality of life of children and adults born very preterm (VPT, < 32 weeks of gestation) or very low birth weight (VLBW, < 1500g) – approximately 50 000 births each year in Europe – by establishing an ICT platform to integrate, harmonise and exploit the wealth of data from 20 European cohorts of VPT/VLBW children and adults and the ...
Voir le projet

 21

 TERMINÉ 

“In Vivo Click PET Imaging Agents”: Improving clinical companion diagnostics (Click-It)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Companion diagnostics are crucial for drug development and disease management with regard to patient selection, therapy planning and monitoring. Nanomedicines such as antibodies have been proven to be optimal disease-targeting agents because they generally exhibit superior target uptake and retention. However, to date, nuclear imaging of nanomedicines has been limited to the use of long-lived isot ...
Voir le projet

 6

 TERMINÉ 

Comorbidity and Synapse Biology in Clinically Overlapping Psychiatric Disorders (COSYN)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

COSYN integrates outstanding European academic and three large Pharma to exploit genomic findings for intellectual disability (ID), autism, and schizophrenia. We capitalise on comorbidity, from clinic to cells and synapses, and have access to large existing samples. We focus on rare genetic variants of strong effect in patients with clinical comorbidity. Our aims are: (1) Understand comorbidity by ...
Voir le projet

 14

 TERMINÉ 

Technology Enabled Adolescent Mental Health (TEAM)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,

There is no health without mental health. 27% of our population are young, and mental health disorders are our leading cause of disability. 50% of mental disorders emerge by 14 yrs, 75% by 24 yrs and, untreated, triple odds of having a mental health disorder in later life. TEAM’s will build a network of expertise and train a new generation of researchers to deliver more effective, affordable and f ...
Voir le projet

 9

 TERMINÉ 

Molecular imaging and targeted therapy of the aggressive phenotype: development of uPAR theranostics for cancer patients (uPET)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,

For practice of personalized medicine in cancer, non-invasive tools for diagnosing at the molecular level are needed. Molecular imaging methods are capable of this while at the same time circumventing sampling error as the whole tumor burden is evaluated.We recently developed and performed the first-ever clinical PET scan of uPAR, a proteolytic system known to be strongly associated with metastati ...
Voir le projet

 1

 TERMINÉ 

Breast Cancer Risk after Diagnostic Gene Sequencing (BRIDGES) (BRIDGES)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

Breast cancer affects more than 360,000 women per year in the EU and causes more than 90,000 deaths. Identification of women at high risk of the disease can lead to disease prevention through intensive screening, chemoprevention or prophylactic surgery. Breast cancer risk is determined by a combination of genetic and lifestyle risk factors. The advent of next generation sequencing has opened up th ...
Voir le projet

 20

 TERMINÉ 

Metal oxide Aided Subsurface Remediation: From Invention to Injection (METAL-AID)

Date du début: 1 juil. 2016, Date de fin: 30 juin 2020,

Thousands of sites across Europe are polluted with toxic metals and organic solvents; many more exist worldwide. As EU population grows, clean water will determine the quality of life and economic stability. Most sites remain contaminated because existing technology is costly and disruptive. Society needs an innovative way to decontaminate soil and groundwater directly underground. In METAL-AID, w ...
Voir le projet

 11

 TERMINÉ 

Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2020,

Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
Voir le projet

 44

 TERMINÉ 

Evidence-based ICT tools for weight loss maintenance (NoHoW)

Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,

Most adults who try to lose weight fail to maintain it. Obesity is a key economic and healthcare challenge for Europe. Effective interventions and commercial programmes for weight loss are widely available, but most people re-gain their lost weight. Currently few comprehensive solutions exist to help Europeans manage weight loss maintenance (WLM).Current research suggests the most promising eviden ...
Voir le projet

 16

 TERMINÉ 

European Gram Negative Antibacterial Engine (ENABLE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

The intensive use and misuse of antibiotics has resulted in some level of antibiotic resistance in essentially all human bacterial pathogens. There is a growing concern that the loss of therapeutic options will present us with a post-antibiotic era where present and future medical advances are negated. Resistant bacteria dramatically reduce the possibilities of treating infections effectively, a ...
Voir le projet

 42

 TERMINÉ 

Translating neuroimaging findings from research into clinical practice (PSYSCAN)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2020,

Abstract 9Neuroimaging (NI) has enormous potential to improve the clinical care of patients with psychiatric disorders, but has yet to deliver. The PSYSCAN project will address this issue directly by developing a NI-based tool that will help clinicians resolve key clinical issues in the management of patients with psychotic disorders. Clinicians will use the tool to assess patients with a standard ...
Voir le projet

 24

 TERMINÉ 

Training network for Research on molecUlar and Biomechanical Interactions in CONnective tissue disorders (RUBICON)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

RUBICON will establish a global network for staff exchange of scientists and for research training focussed on connective tissue disorders. It will bring together leading scientific groups from 5 European and 5 non-European countries who will study the molecular and biomechanical factors involved in the pathophysiology of connective tissues, including tendons, cartilage and bone. The ambitious obj ...
Voir le projet

 5

 TERMINÉ 

Targeting epigenetic REPROGRamming of innate immune cells in Atherosclerosis Management and other chronic inflammatory diseases (REPROGRAM)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Up to 70% of cardiovascular events are not prevented by current therapeutic regimens. In search for additional, innovative strategies, immune cells have been recognized as key players contributing to atherosclerotic plaque progression and destabilization. Particularly the role of innate immune cells is of major interest, following the recent paradigm shift that innate immunity, considered to be in ...
Voir le projet

 11

 TERMINÉ 

Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE) (SCIENCE)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2019,

Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE)With more than 17 million deaths worldwide each year, ischemic heart disease (IHD) caused by coronary artery disease is the most common cause of death and a major cause of hospital admissions in industrialised countries. IHD caused over four million deaths in Europe in the year 2012 constituting 47% of all deaths. Today IHD is th ...
Voir le projet

 9

 TERMINÉ 

Glaucoma – Advanced, LAbel-free High resolution Automated OCT Diagnostics (GALAHAD)

Date du début: 1 déc. 2016, Date de fin: 30 nov. 2019,

The project GALAHAD targets the critical need for better glaucoma diagnostic systems. Glaucoma is an age-related major cause of blindness. The eye disease is characterized by an irreversible damage to the optic nerve head caused by increased intra-ocular pressure. The current screening and basic diagnostics for the disease involve intra-ocular pressure measurement, visual field tests and detection ...
Voir le projet

 10

 TERMINÉ 

Training Network for the Immunotherapy of Cancer (IMMUTRAIN)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,

In the European Union, cancer is the leading cause of death and the overall cancer incidence is still increasing. As a result of expanding efforts to improve cancer outcome, a main paradigm change is occurring in cancer therapy towards individualized medicine. Antibody-based therapies form an integral and constantly growing part of this approach. Antibody-based therapies will strongly influence th ...
Voir le projet

 9

 TERMINÉ 

Lifestyle intervention in the perioperative process through digital service (LIVE INCITE)

Date du début: 1 nov. 2016, Date de fin: 30 juin 2019,

Lifestyle factors of the patient (e.g. smoking, hazardous alcohol drinking and malnutrition) are proven to be independent risk factors negatively impacting health outcome in the perioperative process. Evidence suggests that the implementation of intensive lifestyle intervention programs can significantly reduce the post-surgery complication risk and rehabilitation time . However, implementation of ...
Voir le projet

 4

 TERMINÉ 

A EUropean study on effectiveness and sustainability of current Cardiac Rehabilitation programmes in the Elderly (EU-CaRE)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

Cardiovascular diseases (CVD) cause over 4 million deaths in Europe each year and mass disability: within the coming decades the disability-adjusted life years (DALYs) estimate is expected to rise from a loss of 85 million DALYs in 1990 to a loss of 150 million DALYs globally in 2020. Moreover, patient numbers are expected to rise rapidly in the next decades, due to an ageing society such that th ...
Voir le projet

 11

 TERMINÉ 

Understanding the dynamic determinants of glucose homeostasis and social capability to promote Healthy and active aging (DYNAHEALTH)

Date du début: 1 avr. 2015, Date de fin: 31 mars 2019,

The Gluco-Psychosocial Axis (GPA) concerns the interplay of factors determining glucose metabolism and insulin sensitivity and the neuroendocrine response resulting from exposure to psychosocial stress. A sub-optimal GPA influences the development of type 2 diabetes and related impairments with varying degrees of interplay between genetics and early growth (particularly adiposity and cognitive fun ...
Voir le projet

 14

 TERMINÉ 

Diagnostic Imaging Strategies for Patients with Stable Chest Pain and Intermediate Risk of Coronary Artery Disease: Comparative Effectiveness Research of Existing Technologies (DISCHARGE)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

Coronary artery disease (CAD) is the leading cause of death in high-income countries. Invasive coronary angiography (ICA) is the reference standard for the diagnosis of CAD and allows immediate therapy. However, only 40% of patients undergoing ICA actually have obstructive CAD and ICA has relatively rare but considerable risks. Coronary computed tomography (CT) is the most accurate diagnostic test ...
Voir le projet

 38

 TERMINÉ 

Regenerative treatment of complete Traumatic Spinal Cord injury with a surgical implantation of a biodegradable device with FGF1 and nerve grafts (SC0806)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Today there is no regenerative therapy available for treatment of complete spinal cord injuries (SCI). BioArctic Neuroscience develops a novel treatment of complete SCI. The method is based on the regeneration of functional nerves in the injured spinal cord. Nerve grafts are transplanted into the injured spinal cord, by using a biodegradable device, loaded with a growth factor and nerve grafts (th ...
Voir le projet

 6

 TERMINÉ 

Targeted Action for Curing Trauma Induced Coagulopathy (TACTIC)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

"Trauma remains one of the world’s biggest contributors to the global burden of disease. Predominantly affecting young adults and children, 800,000 European injury related deaths were recorded in 2002. Outcomes for critically injured trauma patients remain poor with severe bleeding, brain injury and tissue damage being associated with high mortality and disability. Nearly half of all trauma fatali ...
Voir le projet

 9

 TERMINÉ 

Free Respiratory Evaluation and Smoke-exposure reductionby primary Health cAre Integrated gRoups (FRESH AIR)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2018,

... technology from EU member states and the US to new contexts and explore a range of implementation science research questions. The new knowledge this generates will be widely disseminated nationally, regionally and internationally, ensuring the scale-up of interventions tested by the project and global impact of research findings. The project will also provide new perspectives on policy issues of ...
Voir le projet

 15

 TERMINÉ 

Pan-European Professional Curriculum for Gynaecologists

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

In Europe there are more than 5 million births each year and about 2 million women have failed pregnancies. Maternal deaths associated with pregnancy and delivery are as high as 30/100.000 births, of which 50% are linked to substandard care. Furthermore about 25.000 babies are stillborn every year and another 25.000 die before their 1st birthday. There are only a few EU-wide agreed health indica ...
Voir le projet

 10

 TERMINÉ 

Translating disease to cardiovascular health (TransCard)

Date du début: 1 sept. 2013, Date de fin: 31 août 2018,

Cardiovascular disease (CVD) is the leading cause of death in Europe and the world. Drugs that lower cholesterol in blood are the most efficient drugs used to date but we are currently still facing a 50-70% residual risk of suffering from CVD. This clearly illustrates an urgent need for the identification, characterization and validation of novel therapeutically relevant targets. Over the last dec ...
Voir le projet

 8

 TERMINÉ 

Screening to improve Health In very Preterm infantS in Europe (SHIPS)

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

... time input from families. This project uses a unique resource – the EPICE cohort of 6675 babies born before 32 weeks of gestational age and surviving to discharge home in 18 geographically diverse regions in 2011/2012 – to assess the impact of these screening programmes on health, care and quality of life for very preterm infants and their families as well as on coverage, ability to meet needs, h ...
Voir le projet

 15

 TERMINÉ 

Leiðbeinendur nemenda og nýráðinna

Date du début: 30 juin 2016, Date de fin: 29 juin 2018,

Every year there are 1600 students in vocational training at the University Hospital. In addition, approximately 150 people recently graduated start working at the hospital. The role of the University Hospital as an educational organisation must be strengthened to contribute to effective learning and successful start in the labour market. Department of Education at the University Hospital is respo ...
Voir le projet

 5

 TERMINÉ 

Towards the elimination of iodine deficiency and preventable thyroid-related diseases in Europe (EUthyroid)

Date du début: 1 juin 2015, Date de fin: 31 mai 2018,

Despite the fact that iodine deficiency (ID) can easily be prevented by iodine fortification of table salt, industrial salt and cattle food, Europe belongs to the worst regions in terms of access to iodized salt and is seriously ID, resulting in the perpetuation of the single most important, preventable cause of brain damage. European ID is due to significant heterogeneity in prevention and monito ...
Voir le projet

 33

 TERMINÉ 

SPP Regions

Date du début: 1 avr. 2015, Date de fin: 31 mars 2018,

The SPP Regions project is aimed at promoting strong networking and collaboration at both the European and sub-national regional level on sustainable and innovative procurement (SPP/PPI), to help promote and embed capacity building and knowledge transfer. At the regional level networking will be promoted to build capacities and transfer skills in sustainable and innovative procurement implementati ...
Voir le projet

 14

 TERMINÉ 

eHealth in Rheumatology (ELECTOR)

Date du début: 1 janv. 2015, Date de fin: 31 mars 2018,

The increasing number of chronic patients in rheumatology calls for further development of the traditional methods for monitoring symptoms. The aim of the ELECTOR project is to develop a web-based ICT platform for home-based monitoring of self-reliant patients with rheumatoid arthritis. This will provide clinicians with a tool that can completely substitute a large proportion of the conventional v ...
Voir le projet

 8

 TERMINÉ 

From Patient Data to Clinical Diagnosis in Neurodegenerative Diseases (PredictND)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

...revious successful Virtual Physiological Human (VPH) projects. An existing decision support tool is enhanced to meet the needs of clinical practice and validated in real conditions across several EU regions. The first goal is to show that modern computer-based models enable earlier and more objective clinical diagnostics. The second goal is to improve cost-efficiency of early diagnostics by devel ...
Voir le projet

 10

 TERMINÉ 

European Clinical Research Infrastructures Network - Integrating Activity (ECRIN-IA)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2017,

...IA project is designed to expand ECRIN partnerships and impact beyond this core activity.Networking activities will promote pan-European expansion, capacity building, and partnership with other world regions, and address the funding issue (WP2). ECRIN-IA will develop e-services, education material to train professionals and patients associations, and communication with users, patients, citizens an ...
Voir le projet

 48

 TERMINÉ 

Improving Outcome of Necrotizing Fasciitis: Elucidation of Complex Host and Pathogen Signatures that Dictate Severity of Tissue Infection (INFECT)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

The overall goal with INFECT is to advance our understanding of the pathophysiological mechanisms, prognosis, and diagnosis of the multifactorial highly lethal NSTIs. The fulminant course of NSTIs (in the order of hours) demands immediate diagnosis and adequate interventions in order to salvage lives and limbs. However, diagnosis and management are difficult due to heterogeneity in clinical presen ...
Voir le projet

 16