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 TERMINÉ 
The objective of the caLIBRAte project is to establish a state-of-the-art versatile Risk Governance framework for assessment and management of human and environmental risks of MN and MN-enabled products. The framework will be a web-based “system-of-systems” linking different models and methods for: 1) screening of apparent and perceived risks and trends in nanotechnology, 2) control banding, quali ...
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 26

 TERMINÉ 

European Network linking informatics and genomics of helper T cells (ENLIGHT-TEN)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2019,

ENLIGHT-TEN is a European Network Linking Informatics and Genomics of Helper T cells: our mission is to provide cross-disciplinary training in cellular immunology and big data analysis such that we train a new generation of researchers to fully exploit the power of emerging technological platforms. Our network of TEN beneficiaries combines T cell expertise with state-of-the-art technologies such a ...
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 11

 TERMINÉ 

Infrastructure for NMR, EM and X-rays for translational research (iNEXT)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

... European network of world class.iNEXT joint research projects (fragment screening for drug development, membrane protein structure, and multimodal cellular imaging) and networking, training and transnational access activities will be important for SMEs, established industries and academics alike. In particular, iNEXT will provide novel access modes to attract new and non-expert users, which are o ...
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 23

 TERMINÉ 
...es of biological data to manage.Data will only generate long-term value if it is Findable, Accessible, Interoperable and Re-usable (FAIR). This requires a scalable infrastructure that connects local, national and European efforts and provides standards, tools and training for data stewardship.Formally established as a legal entity in January 2014, ELIXIR - the European life science Infrastructure ...
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 47

 TERMINÉ 

Metagenomics in Cardiometabolic Diseases (METACARDIS)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2018,

METACARDIS applies a systems medicine multilevel approach to identify biological relationships between gut microbiota, assessed by metagenomics, and host genome expression regulation, which will improve understanding and innovative care of cardiometabolic diseases (CMD) and their comorbidities. CMD comprise metabolic (obesity, diabetes) and heart diseases characterized by a chronic evolution in ag ...
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 18

 TERMINÉ 
Despite a great progress in the management of epilepsy, still one third of patients is refractory to available medications. The incidence of epilepsy is highest in infancy and 50% of children experience epilepsy-related comorbidities, such as developmental delay and autism. The development of epilepsy (epileptogenesis), extensively studied in animals, is barely studied in humans, as patients usual ...
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 16

 TERMINÉ 
One of the greatest challenges facing regulators in the ever changing landscape of novel nano-materials is how to design and implement a regulatory process which is robust enough to deal with a rapidly diversifying system of manufactured nanomaterials (MNM) over time. Not only does the complexity of the MNM present a problem for regulators, the validity of data decreases with time, so that the wel ...
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 46

 TERMINÉ 

Euro-BioImaging Preparatory Phase II - Project (EuBI PPII)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2017,

...eements between EuBI-ERIC and the 1st generation of EuBI Nodes;• establish a procedure to increase EuBI-ERIC membership, so that new countries can continuously join the EuBI-ERIC with clear national benefits and contributions. From Dec 2010 until May 2014, EuBI successfully completed its EU FP7-funded Preparatory Phase I, which addressed key technical and strategic questions and provided a bluepri ...
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 21

 TERMINÉ 

European Medical Information Framework (EMIF)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

In response to the need to tackle increasingly complex medical research questions, a growing amount of human health data is being collected, either in routine Electronic Healthcare Record (EHR) databases, through research-driven cohort studies, in biobanks or related efforts. However, data sources are typically fragmented and contain information gaps which prevent their full exploitation. EMIF aim ...
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 64

 TERMINÉ 

Engaging the EGI Community towards an Open Science Commons (EGI-Engage)

Date du début: 1 mars 2015, Date de fin: 31 août 2017,

... (EGI) has built a distributed computing and data infrastructure to support over 21,000 researchers from many disciplines with unprecedented data analysis capabilities. EGI builds on the European and national investments and relies on the expertise of EGI.eu - a not-for-profit foundation that provides coordination to the EGI Community, including user groups, EGI.eu participants in the EGI Council, ...
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 43

 TERMINÉ 
The main objective of this research proposal is to identify and elaborate those characteristics of ENM that determine their biological hazard potential. This potential includes the ability of ENM to induce damage at the cellular, tissue, or organism levels by interacting with cellular structures leading to impairment of key cellular functions. These adverse effects may be mediated by ENM-induced a ...
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 40

 TERMINÉ 

Innovative technology for cyanobacterial bloom control (LIFE Stop CyanoBloom)

Date du début: 1 juil. 2013, Date de fin: 31 déc. 2016,

Background Cyanobacteria can be found in almost every terrestrial and aquatic habitat. Aquatic cyanobacteria are known for their extensive and highly visible blooms that can form in both freshwater and marine environments. The massive blooms can be toxic and frequently lead to the closure of recreational waters when spotted. Therefore, mass occurrence o ...
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 3

 TERMINÉ 

SYSTEMS BIOLOGY OF PATHWAYS INVOLVING BRAIN AGEING (AGEDBRAINSYSBIO)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

In spite of valuable approaches applied to get a broad understanding of genetic, epidemiologic and molecular and system-level biological principles of human aging, cognitive decline remains as one of the greatest health challenges of the old age, with nearly 50% of adults over 85 afflicted of Alzheimer’s disease. Furthermore, drug development has not performed as expected in clinical trials, at le ...
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 15

 TERMINÉ 

A BLUEPRINT of Haematopoietic Epigenomes (BLUEPRINT)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,

In response to the call for a high impact initiative on the human epigenome, the BLUEPRINT Consortium has been formed with the aim of generating at least 100 reference epigenomes and studying them to advance and exploit knowledge of the underlying biological processes and mechanisms in health and disease. BLUEPRINT will focus on distinct types of haematopoietic cells from healthy individuals and o ...
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 45

 TERMINÉ 

Epigenetics towards systems biology (EPIGENESYS)

Date du début: 1 oct. 2010, Date de fin: 31 mars 2016,

The ‘EpiGeneSys’ Network of Excellence aims to enable European epigenetics research to enter the arena of systems biology, a new step forward with major implications for human health. Many diseases, not explained solely by gene mutation, have rather been associated with epigenetic disorders. Following the identification of key epigenetic regulators, a move towards a systems biology approach is nee ...
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 28

 TERMINÉ 

Electronic Health Record systems for Clinical Research (EHR4CR)

Date du début: 1 mars 2011, Date de fin: 29 févr. 2016,

Current medical needs, the growth of targeted therapies and personalized medicines, and escalating R&D costs result in formidable cost pressures on healthcare systems and the pharmaceutical industry. Clinical research is also growing in complexity, labour intensity and cost. There is a growing realization that the development and integration of Electronic Health Record systems (EHRs) for medical ...
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 37

 TERMINÉ 
...ocesses of biodiversity distribution. Measures to improve protection schemes will be suggested, based on maintaining effective exchanges (biological and hydrological) between protected areas. The national coastal focus of existing MPAs will be widened to both off shore and deep sea habitats, incorporating them into the networks through examination of current legislation, to find legal solutions to ...
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 40

 TERMINÉ 
The central goal of our proposal is to develop physically justified models and computational tools to quantitatively describe and understand the molecular mechanisms of nanoparticle-cell membrane interactions, which we consider to be a crucial point in any predictive model of nanoparticle toxicity. We consider mechanisms of nanoparticle protein corona formation, the protective function of the memb ...
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 4

 TERMINÉ 

Policy-oriented marine Environmental Research in the Southern EUropean Seas (PERSEUS)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

The overall scientific objectives of PERSEUS are to identify the interacting patterns of natural and human-derived pressures on the Mediterranean and Black Seas, assess their impact on marine ecosystems and, using the objectives and principles of the Marine Strategy Framework Directive as a vehicle, to design an effective and innovative research governance framework based on sound scientific knowl ...
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 55

 TERMINÉ 
...l and semantic interoperability with other relevant data management systems and initiatives on behalf of science, environmental management, policy making, and economy. SeaDataNet is undertaken by the National Oceanographic Data Centres (NODCs), and marine information services of major research institutes, from 31 coastal states bordering the European seas, and also includes Satellite Data Centres, ...
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 44

 TERMINÉ 

Network for the Conservation of Cetaceans and Sea Turtles in the Adriatic (NETCET)

Date du début: 30 sept. 2012, Date de fin: 29 sept. 2015,

...hening rescue centre coverage along the Adriatic coast will contribute to the inter-regional conservation effort. 5) Lack of conservation strategies: common policies and management strategies at transnational level are crucial for conservation. The NETCET project, in conformity with the IPA Adriatic CBC Programme priority 2, measure 2.2, Natural and Cultural Resources management and prevention of ...
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 13

 TERMINÉ 

New Algorithms for Host Pathogen Systems Biology (SYSPATHO)

Date du début: 1 oct. 2010, Date de fin: 31 mars 2015,

SYSPATHO focuses on the development of novel and generally applicable mathematical methods and algorithms for systems biology. These methods and algorithms will be applied to study the complex interactions of hepatitis C virus (HCV), a human-pathogenic virus of high medical relevance, with its host at the systems level. Using a multidisciplinary, integrative approach, PATHOSYS will (a) develop met ...
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 11

 TERMINÉ 
...adily respond to major pollution incidents. Namely, this project aims to address concrete problems and needs identified in existing European policies and strategies on sea protection, while at national and regional level it is based on an analysis of the level of preparedness of project partners. The project envisages the setting up of a training and research centre for combating oil spills, and s ...
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 13

 TERMINÉ 

International Human Microbiome Standards (IHMS)

Date du début: 1 févr. 2011, Date de fin: 31 janv. 2015,

...adata. Importantly, it organises public access to the standard operating procedures and protocols and enables exchanges between the users and providers of the standards. It gathers very strong international partnership that includes leaders in the field and represents the current large projects, which span three continents, Europe, Asia and America. Furthermore, it interfaces via the International ...
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 8

 TERMINÉ 
Overall objective of the project is to improve institutional capacity for cooperation between Polish universities and the Ukrainian research institutes and universities from the cross-border areas.Implementation of the project will facilitate the conduct of research by using archival collections. This will allow researchers to strengthen existing contacts and establish new contacts among the parti ...
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 2

 TERMINÉ 

Breast Cancer Somatic Genetics Study (BASIS)

Date du début: 1 juil. 2010, Date de fin: 31 déc. 2014,

...st cancer is a heterogeneous disease with a number of subtypes. We propose here to generate complete catalogues of somatic mutations in 500 breast cancers, of the ER+ve HER2- subclass, under the International Cancer Genome Consortium model by high coverage, shotgun genome sequencing of both tumour and normal DNA. All classes of mutations are expected to be detected including base substitutions, in ...
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 16

 TERMINÉ 

2nd-Generation Open Access Infrastructure for Research in Europe (OpenAIREplus)

Date du début: 1 déc. 2011, Date de fin: 31 déc. 2014,

OpenAIREplus will build a 2nd-Generation Open Access Infrastructure by significantly expanding in several directions the outcomes of the OpenAIRE project, which implements the EC Open Access (OA) pilot. Capitalizing on the OpenAIRE infrastructure, built for managing FP7 and ERC funded articles, and the associated supporting mechanism of the European Helpdesk System, OpenAIREplus will "develop an o ...
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 42

 TERMINÉ 

Synaptic Systems: dissecting brain function in health and disease (SYNSYS)

Date du début: 1 juil. 2010, Date de fin: 31 déc. 2014,

Major disorders of the Central Nervous System (CNS) affect one in three people in the developed world, often seriously disable the affected individual, and together account for the single largest burden on the healthcare systems of the EU. Most of these disorders act at the neuronal synapse, a cellular organelle comprising in the order of 2000 proteins. Pleiotropy, cross-talk between proteins and ...
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 19

 TERMINÉ 
Scientific research is no longer conducted within national boundaries and is becoming increasing dependent on the large-scale analysis of data, generated from instruments or computer simulations housed in trans-national facilities, by using e Infrastructure (distributed computing and storage resources linked by high-performance networks).The 48 month EGI-InSPIRE project will continue the transitio ...
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 143

 TERMINÉ 

Transnational ENhancement of ECOPORT8 network  (TEN_ECOPORT)

Date du début: 30 sept. 2012, Date de fin: 29 sept. 2014,

In the recent years the ports are the hub-point of the Core Regional Transport Networks, as precursors for the TEN-T comprehensive network in the South East Europe. In this direction, a great responsibility was entrusted to the port authorities: they are the authority appointed for the Control and the real application of the Environmental Manage System, being the nodes that ensure the environmenta ...
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 16

 TERMINÉ 

Cancer Genomics of the Kidney (CAGEKID)

Date du début: 1 mars 2010, Date de fin: 31 août 2014,

The International Cancer Genome Consortium (ICGC) has the goal of obtaining a comprehensive description of genomic, transcriptomic and epigenomic changes in 50 different tumour types and/or subtypes, with the aim of elucidating the genomic changes present in the many forms of cancers that contribute to the burden of disease throughout the world. We present a proposal for a European contribution to ...
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 15

 TERMINÉ 
...ss the European member states. To achieve this, Euro-BioImaging will define the legal and governance framework with its currently 22 member states and develop a finance plan in close cooperation with national funding bodies as well as with the European Commission. The key objective of the Euro-BioImaging preparatory phase project is to integrate these plans into an overarching business plan that p ...
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 44

 TERMINÉ 
Major objectives of ERA.Net RUS are: • RAISING KNOWLEDGE on bilateral and national S&T programmes with or towards Russia and on relevant activities of other programme owners; IDENTIFYING STRENGTHS AND CHALLENGES of present bilateral S&T programmes of MS/AC with Russia. • LEARNING LESSONS from ongoing (thematic) ERA-NETs involving Russian programme owners and IDENTIFYING GOOD PRACTICE from other in ...
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 21

 TERMINÉ 

Options for Delivering Ecosystem-Based Marine Management (ODEMM)

Date du début: 1 mars 2010, Date de fin: 30 nov. 2013,

The overall aim of the ODEMM project is to develop a set of fully-costed ecosystem management options that would deliver the objectives of the Marine Strategy Framework Directive, the Habitats Directive, the European Commission Blue Book and the Guidelines for the Integrated Approach to Maritime Policy. This will be achieved by: (i) providing a comprehensive knowledge base to support policy for th ...
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 17

 TERMINÉ 

Indexing for Life (i4Life)

Date du début: 1 nov. 2010, Date de fin: 31 oct. 2013,

Partners to this proposal include the six major global programmes exploring the full extent of species diversity, a core dimension in human knowledge of global biodiversity.They are: GBIF and distribution modelling, the EBI/INDSC, and Barcode of Life initiatives and molecular diversity, IUCN Red Lists and the species conservation movement, and the Species 2000 Catalogue of Life taxonomic framework ...
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 18

 TERMINÉ 
The ECO-Satellite action aims to protecting and preservating the water system of the Black Sea, with its main emphasis given to river deltas and protected coastal regions at the seaside. It deals with environmental problems posing a threat that cannot be addressed individually, but only in an unified way. ...
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 6

 TERMINÉ 
...per species enhanced the exchange of know-how and best practices. The long term sustainability of the project results will be ensured through the creation of European, national and local networks, as well as through the after-LIFE conservation and communication plans. These will ensure the continual updating of the habitat knowledge base, the maintenance of infrastructure and litter removal to m ...
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 3

 TERMINÉ 
...ng these minimal requirements; the specification of efficient data deposition tools and data flow from data producers to public repositories as part of the publication process; implementation of international data exchange among databases; training and exchange of curation staff in the participating databases; and the definition of analysis tools for the efficient use of data following the PSI-MI ...
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 15

 TERMINÉ 
The Black Sea Catchment is internationally known as one of ecologically unsustainable development and inadequate resource management, which has led to severe environmental, social and economic problems. EnviroGRIDS @ Black Sea Catchment aims at building the capacities of regional stakeholders to use new international standards to gather, store, distribute, analyze, visualize and disseminate crucia ...
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 30

 TERMINÉ 

Open Access Infrastructure for Research in Europe (OpenAIRE)

Date du début: 1 déc. 2009, Date de fin: 30 nov. 2012,

The proposed project will deliver "an electronic infrastructure and supporting mechanisms for the identification, deposition, access, and monitoring of FP7 and ERC funded articles", where the main supporting mechanism will be the establishment and operation of the European Helpdesk System. Additionally, the project will offer "a special repository for articles that can be stored neither in institu ...
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 39