4 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
European Lead Factory (EUC²LID)
Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,
The European Lead Factory concept proposed by the EUC2LID Consortium relates to the discovery of novel small molecule candidates to serve as starting points for subsequent optimization to either drug candidates or high-quality pharmacological tools for the experimental validation of targets. The concept intends to bridge academic and applied research interests. The European Lead Factory will provi ...
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34
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TERMINÉ
Innovative anti-influenza drugs excluding viral escape (ANTIFLU)
Date du début: 1 juin 2011, Date de fin: 31 mai 2016,
ANTIFLU is to develop innovative drugs against influenza virus infections based on a novelconcept that precludes the development of viral resistance and ensures efficacy againstupcoming pandemic influenza strains. Viral replication is known to depend on multiple hostfactors. Whilst traditional anti-influenza treatments usually target viral factors, ANTIFLU willaim at drugs interfering with host-re ...
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11
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TERMINÉ
Small molecule stabilizers of 14-3-3 Protein-Protein Interactions as novel drugs in cancer and neurodegenerative diseases (14-3-3Stabs)
Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,
The objective of the application is the development and characterization of small molecule stabilizers of protein-protein interactions (“Molecular Glues”) as a novel class of biological tool compounds and potential therapeutic drugs for the treatment of cancer as well as Alzheimer’s and Parkinson’s Disease, respectively. As biological targets we work on 14-3-3 proteins, an important class of adapt ...
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5
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TERMINÉ
PAthways for Carbon Transitions (PACT)
Date du début: 1 oct. 2008, Date de fin: 30 sept. 2011,
Most «business-as-usual scenarios» built up till now have shown that hydrocarbon resources scarcity and the growing release of greenhouse gases will bring the world far away from sustainability over the next decades. Then, deep changes in behaviours away from «BAU» are unavoidable long before the turn of the century in a move towards a post-carbon society. Urbanisation and mobility are probably ...
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