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Code-engineered new-to-nature microbial cell factories for novel and safety enhanced bio-production (METACODE)
Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,
The concept of METACODE is to preform genetic code engineering in microbial strains with parallel recruitment of novel bio-orthogonal chemistries for mass production of desired protein/peptide based products. In combination with computational and classical chemical synthetic approaches as well as chemo-informatics, enzyme guided evolution, synthetic metabolism, and directed evolution of microbial ...
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