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 TERMINÉ 

Aggression subtyping for improved insight and treatment innovation in psychiatric disorders (AGGRESSOTYPE)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Aggression is a basic physiological trait with important roles throughout evolution, both in defence and predation. When expressed in humans in the wrong context, aggression leads to maladjustment, social impairment and crime. Despite this, knowledge about aggression aetiology is limited and current treatment strategies are insufficient. Contingent to a subdivision into impulsive and instrumental ...
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 27

 TERMINÉ 

Targets and biomarkers for antiepileptogenesis (EPITARGET)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2018,

Epilepsy is a devastating condition affecting over 50 million people worldwide. This multidisciplinary project is focused on the process leading to epilepsy, epileptogenesis, in adults. Our main hypothesis is that there are combinations of various causes, acting in parallel and/or in succession, that lead to epileptogenesis and development of seizures. Our central premise and vision is that a comb ...
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 20

 TERMINÉ 

BEYOND STATE-OF-THE-ART TECHNOLOGIES FOR POWER AC CORRIDORS AND MULTI-TERMINAL HVDC SYSTEMS (BEST PATHS)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2018,

"A group of eight Transmission System Operators with a generator company, manufacturers and research organisations, propose 5 demonstration projects to remove, in 4 years, several barriers which prevent large-scale penetration of renewable electricity production in the European transmission network. The full scale demonstrations led by industry aim at proving the benefits of novel technologies cou ...
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 39

 TERMINÉ 

Global Earth Observation for integrated water resource assessment (eartH2Observe)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

The project eartH2Observe brings together the findings from European FP projects DEWFORA, GLOWASIS, WATCH, GEOWOW and others. It will integrate available global earth observations (EO), in-situ datasets and models and will construct a global water resources re-analysis dataset of significant length (several decades). The resulting data will allow for improved insights on the full extent of availab ...
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 27

 TERMINÉ 

Parasite glycobiology and anti-parasitic strategies (GLYCOPAR)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2017,

"Protozoan parasites and helminths are the cause of some of the most devastating diseases worldwide and a major effort is needed to be able to control or eliminate these diseases. Glycoconjugates are abundant and ubiquitous on the surface of many parasites and they are frequently involved in their survival strategies by forming a protective barrier against host defences. A common feature of the pa ...
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 13

 TERMINÉ 

Collaboration on the Optimisation of Macromolecular Pharmaceutical Access to Cellular Targets (COMPACT)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,

Most biopharmaceuticals (BP) currently on the market are recombinant proteins which are parenterally administered. These would benefit from more patient-friendly routes of administration. Moreover, new classes of BP (e.g. siRNA, miRNA, DARPins) with specificity for intracellular targets hold promise but await the advent of efficient delivery systems before their potential can be realised into ther ...
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 22

 TERMINÉ 

Oral biopharmaceutics tools (ORBITO)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2017,

The OrBiTo project will deliver novel methods and a framework for rational application of predictive biopharmaceutics tools for oral drug delivery. This will be achieved through novel propsective studies to define new methodlogies which will be validated using historical datasets from EFPIA partners. A combination of high quality in vitro or in silico characterizations of API and formulations will ...
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 28

 TERMINÉ 

New Oral Nanomedicines: Transporting Therapeutic Macromolecules across the Intestinal Barrier (TRANS-INT)

Date du début: 1 mai 2012, Date de fin: 30 avr. 2017,

Despite the increasing number of macromolecules with potential impact in the treatment of devastating systemic diseases, these therapies have failed to deliver on their expectations because they cannot be administered in the fashion which is most cost efficient and has the highest patient compliance: the oral route. The availability of an oral form of administration could lead to a great improveme ...
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 20

 TERMINÉ 

European Autism Interventions - A Multicentre Study for Developing New Medications (EU-AIMS)

Date du début: 1 avr. 2012, Date de fin: 31 mars 2017,

Despite dramatic advances in molecular and imaging technologies, there are currently no effective pharmacological treatments for the core symptoms of autism spectrum disorder (ASD). Major obstructions to this include a lack of aetiologically-driven or pathophysiologically-accurate animal models; an absence of tests that indicate efficacy; and reliance of clinical trials on DSM/ICD10 categories wh ...
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 29

 TERMINÉ 

SUSTAINABLE NANOTECHNOLOGIES (SUN)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2017,

SUN (Sustainable Nanotechnologies) is the first project addressing the entire lifecycle of nanotechnologies to ensure holistic nanosafety evaluation and incorporate the results into tools and guidelines for sustainable manufacturing, easily accessible by industries, regulators and other stakeholders. The project will incorporate scientific findings from over 30 European projects, national and inte ...
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 38

 TERMINÉ 

Process Line Implementation for Applied Surface Nanotechnologies (PLIANT)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2017,

...t had insufficient information or could benefit from “upgrading” or justification. Our response and actions against each point raised has been summarized and send to the project officer, Dr. Rene Martins, in a separate document.
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 24

 TERMINÉ 

European clinical study for the application of regenerative heart valves (ESPOIR)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

Acquired and congenital heart disease can necessitate heart valve replacement. However, current heart valve substitutes are not considered ideal as they need anticoagulation, bearing the risk of bleeding when manufactured from non-organic material, or they degenerate when they derive from animals or human tissue donators (homografts) thereby leading to frequent reoperation especially in the young ...
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 15

 TERMINÉ 

"Exploring transitions pathways to sustainable, low carbon societies" (PATHWAYS)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2016,

"The ambitious EU policy goals to move to sustainable, resource efficient, low-carbon and climate-resilient and biodiversity rich societies requires substantial transitions in the energy system and land-use and food systems. Different scientific approaches offer different perspectives on transitions, each with strengths and weaknesses. The PATHWAYS project takes a step in coupling three scientific ...
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 10

 TERMINÉ 

Holistic Human Factors and System Design of Adaptive Cooperative Human-Machine Systems (HOLIDES)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

HoliDes addresses development and qualification of Adaptive Cooperative Human-Machine Sys-tems (AdCoS) where many humans and many machines act together, cooperatively, in a highly adaptive way. They adapt to each other and to the context to guarantee fluent and cooperative task achievement. Such systems with higher levels of automation are urgently needed to enhance safety and to increase the conf ...
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 32

 TERMINÉ 

CLOUD Initial Training Network (CLOUD TRAIN) (CLOUD-TRAIN)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,

"The aim of “CLOUD-TRAIN” is to establish a multi-site network of Early Stage Researchers (here predominantly PhD students) and Experienced Researchers at 10 partner institutions across Europe. The role of aerosol nucleation for atmospheric CCN levels, clouds and climate is investigated. The influence of various vapours and ions for aerosol nucleation, growth and cloud processes is studied to sign ...
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 10

 TERMINÉ 

Development of Systemic Packages for Deep Energy Renovation of Residential and Tertiary Buildings including Envelope and Systems (INSPIRE)

Date du début: 1 oct. 2012, Date de fin: 30 sept. 2016,

Most of the energy consumption in Europe is due to heating and cooling used for domestic, tertiary and industrial purposes; This energy is largely produced by directly burning fossil fuels with a negative environmental impact. RES directive and the SET Plan focuses its attention on the use of RES to drive systems for heating and cooling in order to reduce greenhouse gas emissions and the dependenc ...
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 24

 TERMINÉ 

Large-scale computation without synchronisation (SyncFree)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

The goal of SyncFree is to enable large-scale distributed applications without global synchronisation, by exploiting the recent concept of Conflict-free Replicated Data Types (CRDTs). CRDTs allow unsynchronised concurrent updates, yet ensure data consistency. This revolutionary approach maximises responsiveness and availability; it enables locating data near its users, in decentralised clouds.Glob ...
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 13

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the ...
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 116

 TERMINÉ 

International study for treatment of childhood relapsed ALL 2010 with standard therapy, systematic integration of new agents, and establishment of standardized diagnostic and research (INTREALL)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,

Though survival of children with acute lymphoblastic leukaemia (ALL) has improved, relapse remains a leading cause of mortality in childhood cancer. Given the rarity of the disease, only a large international cooperative group can recruit sufficient patients for prospective studies with specific questions in biologic subgroups. Under the umbrella of the I-BFM SG all relevant mainly European study ...
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 29

 TERMINÉ 

A BLUEPRINT of Haematopoietic Epigenomes (BLUEPRINT)

Date du début: 1 oct. 2011, Date de fin: 30 sept. 2016,

In response to the call for a high impact initiative on the human epigenome, the BLUEPRINT Consortium has been formed with the aim of generating at least 100 reference epigenomes and studying them to advance and exploit knowledge of the underlying biological processes and mechanisms in health and disease. BLUEPRINT will focus on distinct types of haematopoietic cells from healthy individuals and o ...
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 45

 TERMINÉ 

Innovative Reuse of modular knowledge Based devices and technologies for Old, Renewed and New factories (ReBORN)

Date du début: 1 sept. 2013, Date de fin: 31 août 2016,

The vision of ReBORN is to demonstrate strategies and technologies that support a new paradigm for re-use of production equipment in old, renewed and new factories; maximizing the efficiency of this re-use and making the factory design process much easier and straight forward, shortening ramp-up times and increasing production efficiency and flexibility. This paradigm will give new life to decommi ...
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 19

 TERMINÉ 

Advanced Cell-based Therapies for the treatment of Primary ImmunoDeficiency (CELL-PID)

Date du début: 1 nov. 2010, Date de fin: 30 avr. 2016,

Primary immune deficiencies (PID) are inherited disorders of the adaptive and innate immune system marked by severe infections, autoimmunity and high risk of cancer. Treatment entails hematopoietic stem cell (HSC) transplantation from allogeneic donors, however in the absence of an HLA compatible donor, HSCT outcome is limited by delayed or suboptimal reconstitution and complications. SCID-X1 and ...
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 20

 TERMINÉ 

Microbicide Optimization Through Innovative Formulation for Vaginal and Rectal Delivery (MOTIF)

Date du début: 1 oct. 2012, Date de fin: 31 mars 2016,

"The 40% protection against HIV-1 infection with vaginally-applied tenofovir gel demonstrated in the CAPRISA004 trial, has emphasized development of anti-retroviral (ARV)-based microbicides. Combining ARVs in a single product may provide increased protection. Development of a generally applicable formulation platform for combining ARVs (even if chemically incompatible) and understanding of the pro ...
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 9

 TERMINÉ 

Maximizing the integration capacity of the European Union: Lessons and prospects for enlargement and beyond (MAXCAP)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2016,

The ‘big bang enlargement’ of the European Union (EU) has nurtured vivid debates among both academics and practitioners about the consequences of ‘an ever larger Union’ for the EU’s integration capacity. The research project MAXCAP will start with a critical analysis of the effects of the 2004- 2007 enlargement on stability, democracy and prosperity of candidate countries, on the one hand, and the ...
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 9

 TERMINÉ 

Smart Technologies for Transport Safety - Innovation Cluster Nesting (SMART-NEST)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

The main objective of the proposed project is to establish a European-level vibrant training environment in a rapidly emerging research field at the crossroads of structural engineering and smart technologies. The participants link up their cross-sectoral expertise to support their researchers in pursuing an interdisciplinary career and to provide them with a cohesive training environment. The pro ...
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 6

 TERMINÉ 

Translational Training network on the Cellular and Molecular Bases of Heart Homeostasis and Repair (CardioNeT)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

The CardioNeT Initial Training Network aims to implement a highly multidisciplinary, intersectoral and competitive training programme in cardiovascular research through cutting-edge projects and extensive training in complementary areas.CardioNeT training comprises two tightly linked components - research and complementary training - that will be implemented at local as well as network level and ...
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 13

 TERMINÉ 

Smart nano-structured devices hierarchically assembled by bio-mineralization processes (SMILEY)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2015,

"SMILEY aims to develop and apply a ""bottom-up"" approach to build nano-structured devices with smart multi-functional properties: bio-mineralization, self-assembly, self-organization are an ensemble of concomitant phenomena, inspired by nature, that will be properly directed to generate elementary nano-sized building blocks organized in macroscopic devices for application in EHS (Environment, He ...
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 8

 TERMINÉ 

Type 2 diabetes and obesity among sub-Saharan African native and migrant populations: dissection of environment and endogenous predisposition (RODAM)

Date du début: 1 janv. 2012, Date de fin: 30 sept. 2015,

"Migration from Sub-Saharan Africa (SSA) to Europe is increasing. The limited evidence suggests that the risk of type 2 diabetes (T2D) and obesity among SSA migrants is higher than among their SSA peers living in Africa and European host populations. The reasons for these observations are only poorly understood, but may involve migration-related changes in lifestyle, genetic predisposition as well ...
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 9

 TERMINÉ 

Marine Renewables Infrastructure Network for Emerging Energy Technologies (MARINET)

Date du début: 1 avr. 2011, Date de fin: 30 sept. 2015,

Offshore Renewable Conversion systems are mostly at the pre-commercial stage of development. They comprise wave energy and tidal stream converters as well as offshore wind turbines for electrical generation. These devices require research to be undertaken at a series of scales along the path to commercialization. Each technology type is currently at a different stage of development but each one al ...
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 29

 TERMINÉ 

High Integrity Low Distortion Assembly (HILDA)

Date du début: 1 sept. 2012, Date de fin: 31 août 2015,

"HILDA will deliver a cost effective, low distortion welding process for EU shipyards to allow them to maintain competitiveness and produce light, strong, more fuel efficient vessels. The solid state technique will enable the modular construction of dimensionally accurate, high strength, corrosion resistant fabrications across the entire range of steels, enabling the introduction of stronger, toug ...
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 8

 TERMINÉ 

New approaches for the targeted therapy of Non-Small Cell Lung Cancer (LUNGTARGET)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2015,

Lung cancer is the most common cancer fatality in Europe (335000 deaths/yr). Non-small cell lung cancer (NSCLC) consists 85% of the cases, with 5 yr survival
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 10

 TERMINÉ 

Control & Automation Management of Buildings & Public Spaces in the 21st Century (Campus21)

Date du début: 1 sept. 2011, Date de fin: 31 mai 2015,

CAMPUS 21 focuses on the energy-efficient operation of public buildings and spaces. It brings together the expertise of national research centres from Germany (Telecommunications), Ireland (IT in AEC, Artificial Intelligence), Austria (Building Physics), and Spain (Information Technology); the management experience of Public Authorities and bundles this with the process expertise from multiple ind ...
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 10

 TERMINÉ 

Sustainable Plan for Integrated Development through the European Rail network – Projecting Logistics & mobility for Urban Spatial design evolution (SPIDER PLUS)

Date du début: 1 déc. 2012, Date de fin: 31 mai 2015,

"SPIDER PLUS objective is to provide a new 2050 mobility VISION through a Strategic Design & Plan, and a Road Map delivering Sustainable Solutions by then. In such Plan the electrified Rail has a central role both for passengers and freight. The productivity of the available resources supported by ICT and other technologies, is maximized by the combination of infrastructural nodes with spatial and ...
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 14

 TERMINÉ 

Metropolis, Urban Airspace Design (METROPOLIS)

Date du début: 1 oct. 2013, Date de fin: 30 avr. 2015,

This project proposes the investigation of radically new airspace design concepts for scenarios, which are extreme when compared to today in terms of traffic density, complexity and constraints.Extrapolating the current developments in aerospace technology, it is considered likely that the following two new types of air vehicles will have arrived in the second half of this century:- personal air v ...
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 4

 TERMINÉ 

Sub-seabed CO2 Storage: Impact on Marine Ecosystems (ECO2) (ECO2)

Date du début: 1 mai 2011, Date de fin: 30 avr. 2015,

The ECO2 project sets out to assess the risks associated with the storage of CO2 below the seabed. Carbon Capture and Storage (CCS) is regarded as a key technology for the reduction of CO2 emissions from power plants and other sources at the European and international level. The EU will hence support a selected portfolio of demonstration projects to promote, at industrial scale, the implementation ...
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 29

 TERMINÉ 

Breast Cancer Somatic Genetics Study (BASIS)

Date du début: 1 juil. 2010, Date de fin: 31 déc. 2014,

"All cancers arise due to somatically acquired mutations in their genomes which alter the function of key cancer genes. Understanding these critical mutational events underlying cancer development is paramount for advancing prevention, early detection, monitoring and treatment of the disease. Breast cancer is the most common class of cancer diagnosed in women worldwide with more than one million c ...
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 16

 TERMINÉ 

PEDCA Pan-European Data Centre Academy (PEDCA)

Date du début: 1 juil. 2013, Date de fin: 31 déc. 2014,

Data centres are the cornerstones which underpin the digital economy, and create the essential environment for both business and employment to flourish. It is becoming urgent for established data centre states to contribute to R&D, share and develop skills, define standards and promote strategies for network investment. All of these activities will lead to increased trust of new technology such as ...
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 13

 TERMINÉ 

Harmonised eCall European Pilot - Phase 2 (HeERO2)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2014,

The overall objective of HeERO 2 is "To extend HeERO to new Member States or associated countries to demonstrate the scalability of the HeERO solution and to widen the acceptance of eCall."To support this objective there are three aims:(1) to prepare the necessary infrastructure to realize interoperability of "eCall" at European level, (2) to boost Member States investment in the PSAP infrastructu ...
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 42

 TERMINÉ 

Plasma And Nano for New Age “soft” conservation (PANNA)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2014,

The main objective is to develop a novel atmospheric plasma technique for surface cleaning and coating deposition as well as two innovative coatings: a self-diagnostic protective coating and a coating provided with identification marker.The project aims at integrating the new plasma cleaning/deposition technique and the new coatings in a “full-life” protocol spanning surface cleaning and pre-treat ...
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 10

 TERMINÉ 

"THE EUROPEAN ACADEMIC AND INDUSTRY NETWORK FOR INNOVATIVE MARITIME TRAINING, EDUCATION AND R&D" (KNOW-ME)

Date du début: 1 juin 2011, Date de fin: 30 sept. 2014,

"The Community’s maritime sector must sustain and improve its competitive advantage, with the groundwork for future international competitiveness resting with high quality and innovative education and training. Employees in the maritime transport sector need innovative educational opportunities that focus on their special working conditions. The KNow-ME project addresses this need by engendering a ...
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 11