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Plus de 40 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

Paraplegia Prevention in Aortic Aneurysm Repair by Thoracoabdominal Staging with ‘Minimally-Invasive Segmental Artery Coil-Embolization’: A Randomized Controlled Multicentre Trial (PAPA-ARTIS)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Chronic aortic aneurysms are permanent and localized dilations of the aorta that remain asymptomatic for long periods of time but continue to increase in diameter before they eventually rupture. Left untreated, the patients’ prognosis is dismal, since the internal bleeding of the rupture brings about sudden death. Although successful treatment cures the disease, the risky procedures can result in ...
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 26

 TERMINÉ 

Personalised Risk assessment in febrile illness to Optimise Real-life Management across the European Union (PERFORM)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

The management of febrile patients is one of the most common and important problems facing healthcare providers. Distinction between bacterial infections and trivial viral infection on clinical grounds is unreliable, and as a result innumerable patients worldwide undergo hospitalization, invasive investigation and are treated with antibiotics for presumed bacterial infection when, in fact, they ar ...
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 19

 TERMINÉ 

European HIV Vaccine Alliance (EHVA): a EU platform for the discovery and evaluation of novel prophylactic and therapeutic vaccine candidates (EHVA)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Many HIV vaccine concepts and several efficacy trials have been conducted in the prophylactic and therapeutic fields with limited success. There is an urgent need to develop better vaccines and tools predictive of immunogenicity and of correlates of protection at early stage of vaccine development to mitigate the risks of failure. To address these complex and challenging scientific issues, the Eur ...
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 43

 TERMINÉ 

Small vessel diseases in a mechanistic perspective: Targets for InterventionAffected pathways and mechanistic exploitation for prevention of stroke and dementia (SVDs-at-target)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Stroke and dementia rank among the most pressing health issues in Europe. Cerebral small vessel diseases (SVDs) have emerged as a central link between these two major co-morbidities. SVDs account for more than 30% of strokes and at least 40% of dementia cases. They encounter multiple distinct diseases that can be separated based on their underlying genetic defects, risk factors, and clinical prese ...
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 14

 TERMINÉ 

Chromatin and MetabolismChromatin-metabolism interactions as targets for healthy living (ChroMe)

Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,

Metabolic disorders are at pandemic levels. Based on recent estimates, ~50% of Europeans are overweight, 20% are obese and 10% have type II diabetes. Obesity and insulin resistance impact European health to the tune of €110 billion per year. These disorders have genetic, nutritional and lifestyle causes. However, the molecular mechanisms that link nutrients and lifestyle to gene activity and chrom ...
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 12

 TERMINÉ 

European Nuclear Science and Application Research 2 (ENSAR2)

Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,

ENSAR2 is the integrating activity for European nuclear scientists who are performing research in three of the major subfields defined by NuPECC: Nuclear Structure and Dynamics, Nuclear Astrophysics and Nuclear Physics Tools and Applications. It proposes an optimised ensemble of Networking (NAs), Joint Research (JRAs) and Transnational Access Activities (TAs), which will ensure qualitative and qua ...
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 31

 TERMINÉ 

Diaphora: Philosophical Problems, Resilience and Persistent Disagreement (DIAPHORA)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

DIAPHORA serves as a European research and training platform for collaborative research on the nature of philosophical problems, their resilience and the sources of persistent divergence of expert opinion about them, and their relation to conflicts in the practical sphere. More specifically, DIAPHORA’s 3 principal research objectives are (A) to diagnose what makes philosophical problems so resilie ...
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 7

 TERMINÉ 

Training Network for the Immunotherapy of Cancer (IMMUTRAIN)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,

In the European Union, cancer is the leading cause of death and the overall cancer incidence is still increasing. As a result of expanding efforts to improve cancer outcome, a main paradigm change is occurring in cancer therapy towards individualized medicine. Antibody-based therapies form an integral and constantly growing part of this approach. Antibody-based therapies will strongly influence th ...
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 9

 TERMINÉ 

Paratexts of the Bible. Analysis and Edition of the Greek Textual Transmission (PARATEXBIB)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2019,

This project takes a new look at an old text. The Bible is a fundamental book for the history of religious beliefs, cultural history, art history as well as many other fields. For centuries it has been read and copied multiple times. Thousands of medieval manuscripts survive. The process of transmission is considered here from a totally new perspective. While biblical manuscripts have so far been ...
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 2

 TERMINÉ 

MANAGING THE EFFECTS OF MULTIPLE STRESSORS ON AQUATIC ECOSYSTEMS UNDER WATER SCARCITY (GLOBAQUA)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

Water and water-related services are major components of the human wellbeing, and as such are major factors of socio-economic development in Europe; yet freshwater systems are under threat by a variety of stressors (organic and inorganic pollution, geomorphological alterations, land cover change, water abstraction, invasive species and pathogens. Some stressors, such as water scarcity, can be a st ...
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 27

 TERMINÉ 

Health and Environment-wide Associations based on Large population Surveys (HEALS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

Assessing individual exposure to environmental stressors and predicting health outcomes implies that both environmental exposures and epi/genetic variations are reliably measured simultaneously. HEALS (Health and Environment-wide Associations based on Large population Surveys) brings together in an innovative approach a comprehensive array of novel technologies, data analysis and modeling tools th ...
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 37

 TERMINÉ 

Personalised Prognostic Tools for Early Psychosis Management (PRONIA)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

Affective and non-affective psychoses have a major negative impact on human society. They account for 6.3% of the global burden of disease and cost €207 billion per year in Europe alone, making them the most expensive brain-related disorders and even more expensive than cardiovascular diseases. This socioeconomic burden is largely caused by two core disease features: onset in adolescence and early ...
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 13

 TERMINÉ 

Statistical multi-Omics UNDerstanding of Patient Samples (SOUND)

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

Bioinformatic analysis is the biggest bottleneck in many genomic medicine projects. Our objective is to enable researchers to dramatically increase statistically informed use of personal multi-omic data in medicine. Soon, multiple types of omic technologies will be applied to 100,000s of patient-derived samples, with the three-stage goal of better understanding disease biology, discovery of new in ...
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 11

 TERMINÉ 

Volcanic ash: field, laboratory and numerical investigations of processes during its lifecycle (VERTIGO)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

Explosive volcanic eruptions are an unavoidable natural hazard: Volcanic ash, the ejected lethal mixture of crystals, lava, glass and older rocks, is the most far-reaching threat. In April 2010, the ash cloud from Eyjafjall volcano in Iceland, a comparatively small event, paralysed large parts of Europe for up to one week in a manner unique in history. The impact was dramatic: several million pass ...
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 10

 TERMINÉ 

Collaboration on the Optimisation of Macromolecular Pharmaceutical Access to Cellular Targets (COMPACT)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2017,

Most biopharmaceuticals (BP) currently on the market are recombinant proteins which are parenterally administered. These would benefit from more patient-friendly routes of administration. Moreover, new classes of BP (e.g. siRNA, miRNA, DARPins) with specificity for intracellular targets hold promise but await the advent of efficient delivery systems before their potential can be realised into ther ...
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 22

 TERMINÉ 

Long-term effects of early nutrition on later health (EARLYNUTRITION)

Date du début: 1 févr. 2012, Date de fin: 31 oct. 2017,

Nutrition during early development has an important impact on later health, particularly through greater obesity risk, as demonstrated by FP6 EARNEST. EarlyNutrition explores the current key hypotheses on likely causes and pathways to prevention of early life origins of obesity (specifically adiposity) and associated disorders. We bring extraordinary expertise and study populations of 470,000 indi ...
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 40

 TERMINÉ 

Individualised Diagnostics and Rehabilitation of Attention (INDIREA)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"We propose a training network based around a linked set of research projects which attempt to improve the diagnosis and rehabilitation of neuropsychological disorders of attention, with each project linked to an external industrial partner in order to commercialise emerging diagnostic and rehabilitation procedures. New diagnostic procedures will link clinical measures of attentional disorders to ...
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 8

 TERMINÉ 

Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter Defibrillators in EUrope (EU-CERT-ICD)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

An estimated 500.000 sudden cardiac deaths (SCD) occur each year in the European Union. Patients at risk for SCD may benefit from prophylactic treatment with an implantable cardioverter-defibrillator (ICD). ICD implantations have dramatically increased in recent years leading to multi-billion Euros of costs with significant regional disparities across Europe. Information on risks, benefits and cos ...
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 27

 TERMINÉ 

Calcium- and light signals in photosynthetic organisms (CALIPSO)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

"CALIPSO is a genuine interdisciplinary and intersectorial research network composed of nine academic research institutions and three industrial partners, thus presenting an example of true translational research and training of young researchers in communicating and transferring achievements from different model organisms directly to industrial partners. CALIPSO aims at identifying environmentall ...
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 11

 TERMINÉ 

Mental Health Training through Research Network in Europe (MARATONE)

Date du début: 1 avr. 2013, Date de fin: 31 mars 2017,

"MARATONE is a Marie Curie Initial Training Network proposal that directly addresses the need for high-level training and career pathways in mental health to increase the inter-sectorial and trans-national employability of young scientists in the academic, public and private sectors to meet the enormous challenge of the 2009 EU Parliament Resolution on Mental Health. The Resolution set out recomme ...
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 14

 TERMINÉ 

Engineered nanomaterial mechanisms of interactions with living systems and the environment: a universal framework for safe nanotechnology (NANOMILE)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

The NanoMILE project is conceived and led by an international elite of scientists from the EU and US with the aim to establish a fundamental understanding of the mechanisms of nanomaterial interactions with living systems and the environment, and uniquely to do so across the entire life cycle of nanomaterials and in a wide range of target species. Identification of critical properties (physico-che ...
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 30

 TERMINÉ 

"Identification, homing and monitoring of therapeutic cells for regenerative medicine – Identify, Enrich, Accelerate" (IDEA)

Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,

"Regenerative medicine focuses on repairing or replacing tissue or organ function lost due to damage or congenital defects using appropriate cells for therapy that have healing capacities like stem cells or progenitor cells. Although regenerative medicine has the potential for more effective therapeutic interventions major improvement in three areas are still needed for a wider establishment of su ...
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 11

 TERMINÉ 

Change in Policy Fields: The Impact of International and Domestic Factors on Morality Policies in 25 OECD Countries Between 1980 and 2010 (MORAPOL)

Date du début: 1 sept. 2010, Date de fin: 31 août 2016,

"MORAPOL pursues two basic objectives that entail both empirically and theoretically fundamental advances of the state-of-the-art. First, MORAPOL takes an innovative empirical focus. It is the first to provide systematic empirical knowledge on the development of morality policies. This policy area is so far unexplored from a policy-analytical perspective. The focus is on changing patterns of moral ...
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 2

 TERMINÉ 

OPtimization of Treatment and Management of Schizophrenia in Europe (OPTiMiSE) (OPTiMiSE)

Date du début: 1 févr. 2010, Date de fin: 31 juil. 2016,

OPTiMiSE (OPtimization of Treatment and Management of Schizophrenia in Europe) will focus on two goals: optimising current treatments in Schizophrenia and explore novel therapeutic options for schizophrenia. The project intends to both address basic, but so far unanswered, questions in the treatment of schizophrenia and develop new and experimental interventions. It is expected that the project wi ...
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 25

 TERMINÉ 

European Network for the Study of Adrenal Tumours - Structuring clinical research on adrenal cancers in adults (ENS@T-CANCER)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2016,

Among patients with adrenal masses Adrenocortical carcinoma (ACC) and malignant pheochromocytomas (MPH) are found with a low incidence but very unfavorable prognosis. Due to this poor clinical outcome, concomitant hormone dysregulation and limited treatment options the two cancer entities severely impact on affected patients. However, the rarity of the tumors also impedes clinical studies which ar ...
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 17

 TERMINÉ 

PSYcho-Social Support in CRISis Management (PsyCris)

Date du début: 1 juil. 2013, Date de fin: 30 juin 2016,

With the overall objective to improve psycho-social support in crisis management, the proposed project PsyCris (36-months) has the following goals: (1) status quo analysis of psychological and medical support in crises in European countries, (2) improvement of support strategies for victims and crisis managers, (3) enhancement of psycho-medical preparedness for major incidents (contingency planni ...
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 10

 TERMINÉ 

"Innotive Training Environment for Researchers Combining the Resources of Statistical Science, Informatics & Genetics" (INTERCROSSING)

Date du début: 1 mai 2012, Date de fin: 30 avr. 2016,

"The principal strategic objective of INTERCROSSING is the cultivation of a new type of young researcher to deal with challenges of exploiting the latest Next Generation Sequencing (NGS) technologies – individuals with rigorous training in three disciplines hardly ever found together any one young scientist: population genetics, informatics and statistics. The need for this supra-disciplinary com ...
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 10

 TERMINÉ 

Low Dose Research towards Multidisciplinary Integration (DOREMI)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2015,

The aim of DoReMi is to promote the sustainable integration of low dose risk research in Europe in order to aid the effective resolution of the key policy questions identified by the High Level Expert Group (HLEG) on Low Dose Risk Research (www.hleg.de). DoReMi provides an operational tool for the development of the proposed MELODI platform (Multidisciplinary European Low Dose Risk Re-search Initi ...
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 39

 TERMINÉ 

Managing Risks of Nanoparticles (MARINA)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

While there are standard procedures for product life cycle analysis, exposure, hazard, and risk assessment for traditional chemicals, is not yet clear how these procedures need to be modified to address all the novel properties of nanomaterials. There is a need to develop specific reference methods for all the main steps in managing the potential risk of ENM. The aim of MARINA is to develop such ...
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 54

 TERMINÉ 

Treat Iron-Related Childhood-Onset Neurodegeneration (TIRCON)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2015,

Neurodegeneration with brain iron accumulation (NBIA) is a heterogeneous group of rare hereditary neurodegenerative disorders characterized by high levels of brain iron. The most common form is pantothenate kinase-associated neurodegeneration (PKAN). Classic PKAN and most other NBIA cases are characterised by early childhood onset and rapid progression. Currently, there is no proven therapy to hal ...
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 14

 TERMINÉ 

Biology and control of vector-borne infections in Europe (EDENext)

Date du début: 1 janv. 2011, Date de fin: 30 juin 2015,

To address the call for proposals 'Biology and control of vector-borne infections in Europe' launched by the European Commission, we want to investigate the biological, ecological and epidemiological components of vector-borne diseases (VBD) introduction, emergence and spread, and to propose innovative tools for controlling them, building on the basis of acquired knowledge. We have selected the ma ...
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 54

 TERMINÉ 

Pharmacoepidemiolocal Research on Outcomes of Therapeutics by a European ConsorTium (PROTECT)

Date du début: 1 sept. 2009, Date de fin: 30 avr. 2015,

Recent pharmacovigilance (PV) issues have led to questions regarding the ability of the current PV system to meet the global needs. Controversies around the assessment of spontaneous reports and conflicting results from pharmacoepidemiology studies may lead to delay in, or inappropriate, regulatory decisions. The PROTECT consortium, consisting of 20 core partners lead by the European Medicines Age ...
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 36

 TERMINÉ 

Aerosols, Clouds, and Trace gases Research Infrastructure Network (ACTRIS)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2015,

Climate change is for a large part governed by atmospheric processes, in particular the interaction between radiation and atmospheric components (e.g. aerosols, clouds, greenhouse and trace gases). Some of these components are also those with adverse health effects influencing air quality. Strengthening the ground-based component of the Earth Observing System for these key atmospheric variables ha ...
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 29

 TERMINÉ 

THERAPEUTIC AND PREVENTIVE IMPACT OF NUTRITIONAL LIPIDS ON NEURONAL AND COGNITIVE PERFORMANCE IN AGING, ALZHEIMER’S DISEASE AND VASCULAR DEMENTIA (LIPIDIDIET)

Date du début: 1 août 2008, Date de fin: 31 mars 2015,

Major objective: It is our aim to develop a lipid based diet that is able to delay or prevent onset of Alzheimer’s disease and related diseases and has a stabilizing effect on cognitive performance in aging. Multiple lines of evidence suggest that there is a large overlap between risk factor of these three diseases. Importantly, there is equally strong evidence that prevention and treatment of the ...
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 19

 TERMINÉ 

Modelling basis and kinetics of nanoparticle interaction with membranes, uptake into cells, and sub-cellular and inter-compartmental transport (NANOTRANSKINETICS)

Date du début: 1 nov. 2011, Date de fin: 31 oct. 2014,

The prediction of biological (and in particular toxicological) impacts has, as its basic pre-requisite, the correct prediction of the sites of action and localization of the nanoparticle in living organisms. We have identified the need for a paradigm shift in modelling these properties for nanoscale objects. The interactions between bare particles and organisms (cells, biological barriers) is radi ...
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 3

 TERMINÉ 

Euro-BioImaging - Research infrastructure for imaging technologies in biological and biomedical sciences (Euro-BioImaging)

Date du début: 1 déc. 2010, Date de fin: 31 mai 2014,

Euro-BioImaging brings together imaging technologies stretching from basic biological imaging with advanced light microscopy, in vivo molecular imaging of single cells to animal models up to the clinical and epidemiological level of medical imaging of humans and populations. Euro-BioImaging, in close consultation with its stakeholders, will address the imaging requirements of both biological and m ...
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 44

 TERMINÉ 

“Effect of diet on the mental performance of children” (NUTRIMENTHE)

Date du début: 1 mars 2008, Date de fin: 31 déc. 2013,

Current evidence on the effect of diet on mental performance (MP) is largely based on animal, retrospective studies, and short-term nutritional intervention studies in humans. NUTRIMENTHE will significantly improve this knowledge through studying the role, mechanisms, risks & benefits of specific nutrients & food components to respond to specific needs and improve the MP of children. The research ...
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 22

 TERMINÉ 

Nucleosome Structure & Function across Biological Scales and Biological Function (NUCLEOSOME4D)

Date du début: 1 nov. 2009, Date de fin: 31 oct. 2013,

Chromatin packages a few meters of DNA into a nucleus measuring a few microns. This tight folding occurs by assembling DNA with histones into so-called nucleosomes, thus ensuring the mechanical stability of our genome. On the flipside, this makes nucleosomes a formidable obstacle to the machines that read, copy or repair its DNA message. One of the fundamental questions in biology is to understand ...
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 17

 TERMINÉ 

"Early diagnosis, treatment and prevention of mood disorders targetting the activated inflammatory response system" (MOODINFLAME)

Date du début: 1 nov. 2008, Date de fin: 30 avr. 2013,

"Partners come from 10 European countries to achieve two main objectives: A) The further exploration of 3 animal models (the OBX rat, GS rat and NOD mouse) characterized by an activated immune response system (IRS), an abnormal tryptophan catabolism and a depressive-like behaviour to study the pathogenesis of inflammation-related mood disorders and the efficacy/working mechanism of anti-inflammat ...
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 21

 TERMINÉ 

Tools for Brain-Computer Interaction (TOBI)

Date du début: 1 nov. 2008, Date de fin: 31 janv. 2013,

TOBI will develop practical technology for brain-computer interaction; i.e., non-invasive BCI prototypes combined with other assistive technologies (AT) that will have a real impact in improving the quality of life of disabled people. These non-invasive BCI are based on electroencephalogram (EEG) signals. The expected impact of TOBI is a wide-spread use of BCI assistive technology endowed with ada ...
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 14