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 TERMINÉ 
Antimicrobial resistance (AMR) is a major global public health threat, and most troublesome is the rapid emergence and dissemination of multidrug resistant (MDR) Enterobacteriaceae, Acinetobacter species and Pseudomonas aeruginosa. There is an unmet medical need to prevent P. aeruginosa infection in critically ill patients and to develop new antibiotics for infections caused by Gram-negative bacte ...
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 44

 TERMINÉ 
AFLoNext is a four year EC L2 project with the objective of proving and maturing highly promising flow control technologies for novel aircraft configurations to achieve a quantum leap in improving aircraft’s performance and thus reducing the environmental footprint. The project consortium is composed by forty European partners from fifteen countries. The work has been broken down into seven work p ...
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 41

 TERMINÉ 

European Facility for Airborne Research in Environmental and Geo-sciences (EUFAR2)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,

EUFAR aims at providing researchers with Open Access to the airborne facilities the most suited to their needs. EUFAR thus allocates Transnational Access to 21 installations, develops a culture of co-operation between scientists and operators, and organizes training courses to attract young scientists to airborne research. To improve the quality of the service, EUFAR supports the experts on airbor ...
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 24

 TERMINÉ 
The overall goal with INFECT is to advance our understanding of the pathophysiological mechanisms, prognosis, and diagnosis of the multifactorial highly lethal NSTIs. The fulminant course of NSTIs (in the order of hours) demands immediate diagnosis and adequate interventions in order to salvage lives and limbs. However, diagnosis and management are difficult due to heterogeneity in clinical presen ...
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 16

 TERMINÉ 

Low-toxic cost-efficient environment-friendly antifouling materials (BYEFOULING)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2017,

... all along their life cycle. A proof-of-concept for the most promising candidates will be developed and demonstrators will be produced and tested on fields.BYEFOULING will combine a multidisciplinary leading research team from 11 European countries, which are already acting worldwide in the scientific community, with highly relevant and skilled technological partners, to build a consortium able to ...
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 19

 TERMINÉ 
MARS-EV aims to overcome the ageing phenomenon in Li-ion cells by focusing on the development of high-energy electrode materials (250 Wh/kg at cell level) via sustainable scaled-up synthesis and safe electrolyte systems with improved cycle life (> 3000 cycles at 100%DOD). Through industrial prototype cell assembly and testing coupled with modelling MARS-EV will improve the understanding of the age ...
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 17

 TERMINÉ 
...ally respected centre, providing robust, reliable and timely delivery of hiPSCs; ensures the biorepository only houses quality assured hiPSC lines; and reduces unwanted variability in assays. We have leading experts in hiPSC differentiation, providing protocols with over 99% efficiency in producing cortical excitatory neurons and cardiomyocytes, which following up-scaling will meet demands of high ...
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 38

 TERMINÉ 
...‘proof-of-concept’ studies, the cohesion of structural neuroimaging studies (MRI/DTI), neurochemistry (MRS/microdialysis), behavior, genetics (GWAS), proteomics and (Bayesian) machine learning tools in both male and female paediatric clinical populations and behavioral animal models will seek to better understand underlying mechanisms related to glutamate dysfunction in frontostriatal circuits and ...
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 13

 TERMINÉ 

Integrated Approaches to Food Allergen and Allergy Risk Management (IFAAM)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

Up to 20 million European citizens suffer from food allergy. However management of both food allergy (by patients and health practitioners) and allergens (by industry) is thwarted by lack of evidence to either prevent food allergy developing or protect adequately those who are already allergic. iFAAM will develop evidence-based approaches and tools for MANAGEMENT of ALLERGENS in FOOD and integrate ...
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 46

 TERMINÉ 

SYSTEMS BIOLOGY OF PATHWAYS INVOLVING BRAIN AGEING (AGEDBRAINSYSBIO)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

...the greatest health challenges of the old age, with nearly 50% of adults over 85 afflicted of Alzheimer’s disease. Furthermore, drug development has not performed as expected in clinical trials, at least in part because of an insufficient mechanistic understanding at the systemic level in human. AgedBrainSYSBIO is a timely and straightforward project based on the integration of available transcrip ...
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 15

 TERMINÉ 
...emerging mouse mutant resource, mouse models must be preserved and made available to the European biomedical research community. To this effect, the Infrafrontier-I3 project brings together the leading European centers for systemic phenotyping of mouse mutants and the European Mouse Mutant Archive network. The Infafrontier-I3 partners aim to meet the future challenges presented by phenotyping, arc ...
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 24

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

...the platforms, implement a policy of Responsible Innovation, and a programme of transdisciplinary education, and develop a framework for collaboration that links the partners under strong scientific leadership and professional project management, providing a coherent European approach and ensuring effective alignment of regional, national and European research and programmes. The project work pla ...
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 116

 TERMINÉ 
...The visual pathway is a component of the central nervous system (CNS) and therefore is not regenerative. Acute optic nerve injury, ischemic optic neuropathy and glaucoma are conditions that initially lead to partial blindness and eventually could lead to total blindness. Extensive neuron and retinal ganglion cells (RGC) death is evidenced in these pathologies. Semaphorin 3A (Sema3A) is a cell secr ...
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 5

 TERMINÉ 

Micro-TRIGENERATION (MICRO-TRIGENERATION)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2016,

Initial situation: The operation of small power plants (e.g. for households) for electricity, heat and cold (micro trigeneration) requires new solution trials. There are systems required, which are user-friendly, low-maintenance, economic. The new Schukey engine unites provide these attributes. The Schukey engine shows an ingenious concept (“universality as a concept”) and works at a temperature o ...
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 6

 TERMINÉ 

Predictive toxicology of engineered nanoparticles (PRENANOTOX)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,

...tivity, hydrophobicity, or surface electrostatics) as well as its other physical properties (e.g. size and shape) determine the strength of the non-specific adsorption of NPs to a cell surface, leading beyond a certain adhesion-strength threshold, to efficient uptake of the NPs; (3) There is a need to extend the traditional QSAR paradigm to the field of nanotoxicology – This will be carried out by ...
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 3

 TERMINÉ 

Smart Intelligent Aircraft Structures (SARISTU)

Date du début: 1 sept. 2011, Date de fin: 31 août 2015,

...r the skin material and its bonding to the substructureis challenging. It is the aim of this project proposal to demonstrate the structuralrealizability of individual morphing concepts concerning the leading edge, the trailing edge and thewinglet on a full-size external wing by aerodynamic and structural testing.Operational requirements on morphing surfaces necessitate the implementation of an ind ...
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 68

 TERMINÉ 
...ale interactions with living organisms. By working with new and emerging scientific research communities from medicine, biology, energy, materials and others, it will seek to forge new directions leading to new (safe, responsible, economically viable) technologies for the benefit of European society.
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 33

 TERMINÉ 
Major objective: It is our aim to develop a lipid based diet that is able to delay or prevent onset of Alzheimer’s disease and related diseases and has a stabilizing effect on cognitive performance in aging. Multiple lines of evidence suggest that there is a large overlap between risk factor of these three diseases. Importantly, there is equally strong evidence that prevention and treatment of the ...
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 19

 TERMINÉ 
The LCAOS project will develop and test a new diagnostic tool, able to detect:(i) the presence of lung cancer (LC), and(ii) an increased risk of a patient developing LC in the future.Diagnostic tests currently available are unsuitable for widespread screening because they are costly, occasionally miss tumours, are not time-efficient, nor free of complications.LCAOS will overcome these problems by ...
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 9

 TERMINÉ 

Secured Urban Transportation - European Demonstration (SECUR-ED)

Date du début: 1 avr. 2011, Date de fin: 30 sept. 2014,

"SECUR-ED Project federates, with a delegated management and in a balanced manner, major operators and top industrial integrators to enhance the security of urban public transportation in medium and large cities, through live demonstrations.Based on the best practices, in a very diverse societal and legacy environment, SECUR-ED will aggregate a consistent and interoperable mix of technologies and ...
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 44

 TERMINÉ 
...sortium will achieve this by: • Conducting an extensive and focused programme of basic/clinical research to improve the diagnosis and management of MDR-TB • Develop a broad training curriculum leading to the creation of a new generation of scientists and clinicians expert in the management of drug resistant TB • Create field sites across the EU with the capacity for evaluating new diagnostic s ...
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 32

 TERMINÉ 

EURAXLES: Minimizing the risk of fatigue failure of railway axles (EURAXLES)

Date du début: 1 nov. 2010, Date de fin: 30 avr. 2014,

"EURAXLES is a 3 year R&D project uniting 23 partners across Europe including 6 axle manufacturers, 4 railway operators/IMs, 2 system integrators, 3 technology suppliers, 5 universities, 2 rail sector associations and 1 consulting firm. The consortium is well-positioned to provide a common R&D approach to axle design, protection, inspection and maintenance which will have an impact on standards, r ...
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 24

 TERMINÉ 

Architecting Manufacturing Industries and systems for Adaptability (AMISA)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2014,

Systems provide value through their ability to fulfill stakeholders’ needs. Inevitably, these needs evolve over time and diverge from an original system’s capabilities. Thus, the system must be disposed of or periodically upgraded at substantial cost.The objective of the AMISA project is to develop a generic, quantitative methodology for architecting manufacturing lines, product systems and custom ...
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 9

 TERMINÉ 

Lithium-Air Batteries with split Oxygen Harvesting and Redox processes (LABOHR)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2014,

...o overcome the energy limitation for the application of the present Li-ion technology in electric vehicles with the goal to: 1- perform frontier research and breakthrough work to position Europe as a leader in the developing field of high energy, environmentally benign and safe batteries and to maintain the leadership in the field of ILs; 2- develop appropriate electrolytes and nanostructured elec ...
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 11

 TERMINÉ 

Railway Induced Vibration Abatement Solutions (RIVAS)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2013,

"Ground vibration, effected by rail services, is an important environmental concern, affecting European citizens nearby any rail infrastructure. Surveys show that many Europeans are subjected to annoying levels of feelable vibration and vibration-induced noise. Although solutions are available for track in tunnels, tracks at grade are a much more extensive problem even for vibration-induced noise. ...
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 27

 TERMINÉ 
The exponential increase in microbial genome and metagenome sequencing throughput has widened the gap between sequence and functional understanding. A clear picture of metabolic processes across the spectrum of bacterial species is essential to enable the exploitation of microbial genomics for the purposes of environmental biotechnology. The Microme project endeavors to extend the scope of microbi ...
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 16

 TERMINÉ 

Sponge Enzymes and Cells for Innovative AppLications (SPECIAL)

Date du début: 1 déc. 2010, Date de fin: 30 nov. 2013,

...production of biosilica and recombinant technology for the production of marine collagen.Research on cellular metabolites will be based upon our recent finding that non-growing sponges continuously release large amounts of cellular material. Production of biosilica will be realized through biosintering, a novel enzymatic process that was recently discovered in siliceous sponges. Research on sponge ...
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 11

 TERMINÉ 
European Commission Vice President Günter Verheugen, responsible for enterprise and industry policy declared "European industries need predictability in the flow of raw materials and stable prices to remain competitive. We are committed to improve the conditions of access to raw materials, be it within Europe or by creating a level playing field in accessing such materials from abroad.” The global ...
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 14

 TERMINÉ 

EUROPEAN FACILITY FOR AIRBORNE RESEARCH IN ENVIRONMENTAL AND GEOSCIENCE (EUFAR)

Date du début: 1 oct. 2008, Date de fin: 30 sept. 2013,

"EUFAR is the Integrating Activity for airborne research in Geo-science. It will integrate the airborne community, to ensure thatresearchers may have access to the most suited infrastructure they need, irrespective of the location of the infrastructure. TheEUFAR consortium comprises 32 legal entities. 14 operators of airborne facilities, and 18 experts in airborne research. Theycontribute to 9 Net ...
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 34

 TERMINÉ 
...tions in audio signal design and life sciences (proteomics). The evaluation will be done by our industrial consortium partners together with our advisory board consisting of one SME, one world market leader and two internationally highly recognized scientific experts.
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 11

 TERMINÉ 

Privacy - Appraising Challenges to Technologies and Ethics (PRACTIS)

Date du début: 1 janv. 2010, Date de fin: 31 mars 2013,

...ptions of privacy will be surveyed (including among high school students). These empirical studies will provide the basis for future scenarios of the privacy-technology interface which in turn will lead to the formulation of new ethical frameworks and legal considerations. Research methods will include interviews, expert surveys, focus groups, and brainstorming. PRACTIS will generate deeper knowle ...
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 8

 TERMINÉ 

European Network for Cell Imaging and Tracking Expertise (ENCITE)

Date du début: 1 juin 2008, Date de fin: 30 nov. 2012,

...areas, are still poorly understood. The ability to non-invasively monitor the fate and modes of action of transplanted cells over time is mandatory. The development of relevant imaging tools will lead to a better understanding of how cell therapy works, the possibility of response monitoring in patients, and sufficient safety of the treatment.. ENCITE will provide tools to allow this by developing ...
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 30

 TERMINÉ 

Nano Health-Environment Commented Database (NHECD)

Date du début: 1 déc. 2008, Date de fin: 30 nov. 2012,

...anding from free text, which is in particular suited to create a comprehensive database in the nano-particles area; and secondly creating automated tools for appropriate evolving ontology assisted by leaders in toxicity in Europe. The team has proven mathematical and computerized world level skills in the general area of Information Technology pertained to database, data warehouse and text mining ...
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 4

 TERMINÉ 
... inability of heart muscle tissue to regenerate itself and appropriate vascularization under conditions of increased strain caused by the reduced contractibility of the damaged heart. This frequently leads to continuous loss of functional cells, further increase of the infarct area and finally complete loss of heart function. We propose to explore possibilities for cell therapy using different pr ...
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 9

 TERMINÉ 

MOVE – towards Energy Sustainability (MOVE)

Date du début: 30 avr. 2009, Date de fin: 29 avr. 2012,

To reduce CO2 emissions.- To protect the primary sources of energy.- Increasing diversification of supply and use of energy resources.- Increasing the share of renewable energies in the primary energy balance of Slovenia and Austria.- To reduce the final energy consumption.- The overall development of skills in the field of energy efficiency and renewable energy sources.- To develop a common regio ...
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 9

 TERMINÉ 
...health and disease, placing particular emphasis on cancer and AIDS. The consortium will create a unique database integrating existing and accumulating knowledge on lethal signal transduction pathways leading to apoptosis or non-apoptotic (necrotic, autophagic, mitotic) cell death, perform data mining to integrate system-wide analyses on cell death (genome, epigenome, transcriptome, proteome, lipid ...
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 24

 TERMINÉ 

Superior Energy and Power Density Li-Ion Microbatteries (SUPERLION)

Date du début: 1 sept. 2008, Date de fin: 31 août 2011,

...mplementation in fully integrated thin-film 3D-MBs with current and power densities per unit footprint area of 70-100 μAh and 150-200 μW for 50-100 reversible cycles. • Implementation of at least some of these 3D-MB concepts in conventional normal-scale Li-ion battery fabrication. • ""Proof-of-concept"" by showing that some 3D-MB device from the project can power both a MEMS and a medical device. ...
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 9

 TERMINÉ 
The adoption of multi- and many-core chips as the architecture-of-choice for mainstream computing will undoubtedly bring about profound changes in the way software is developed. In particular, the use of fine grained locking as the multi-core programmer's coordination methodology is viewed by most experts as a dead-end.The transactional memory (TM) programming paradigm is a strong contender to bec ...
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 11

 TERMINÉ 

Enabling Grids for E-sciencE III (EGEE-III)

Date du début: 1 mai 2008, Date de fin: 30 avr. 2010,

...e, allowing researchers in all regions to collaborate on common challenges. Worldwide collaborations have extended its reach to the benefit of European science.The proposed EGEE-III project has two clear objectives that are essential for European research infrastructures: to expand, optimize and simplify the use of Europe's largest production Grid by continuous operation of the infrastructure, su ...
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 167

 TERMINÉ 
Meeting the management training needs of SMEs : Small businesses form a vital part of national economies, but in order to remain competitive they have to keep the skills of their staff up to date. With the continuing trend towards the globalisation of business, this means that SMEs also need to think internationally and ensure that their management teams are up to the challenge of international tr ...
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 7