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36 projets européens trouvés

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 TERMINÉ 

Releasing the full potential of Instruct to expand and consolidate infrastructure services for integrated structural life science research (INSTRUCT-ULTRA)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Instruct-Ultra aims to advance the scope and efficiency of implementation of Instruct and consolidate the foundations for long-term sustainability. This will be achieved through specific objectives: expand Instruct membership to new Member States and increase global links; engage new user communities; improve efficiencies in service delivery; improve data capture and management; adjust the scale a ...
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 19

 TERMINÉ 

Development of biomaterials through mimesis of plant defensive interfaces to fight wound infections (MIMESIS)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

Fighting microbial infection of wounds, especially in immunocompromised patients, is a major challenge in the 21st century. The skin barrier is the primary defence against microbial (opportunistic) pathogens. When this barrier is breached even non-pathogenic fungi may cause devastating infections, most of which provoked by crossover fungi able to infect both plant and humans. Hence, diabetic patie ...
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 1

 TERMINÉ 

FLow Induced Phase Transitions, A new low energy paradigm for polymer processing (FLIPT)

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

Currently there is no truly sustainable pathway for the production of plastics, an industry which in the EU employs 1.45M people, has a turnover of €89B but consumes ~778GWh of energy per annum. This is an opportunity for industry with pressure increasing to develop low energy, high-quality, wet-processing techniques for consumer products. Here Nature may provide us with inspiration, as over hundr ...
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 8

 TERMINÉ 

Infrastructure for NMR, EM and X-rays for translational research (iNEXT)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials.iNEXT (infrastructure for NMR, EM and X-rays for Translational rese ...
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 23

 TERMINÉ 

Exploiting native endowments by re-factoring, re-programming and implementing novel control loops in Pseudomonas putida for bespoke biocatalysis (EmPowerPutida)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2019,

We aim to engineer the lifestyle of Pseudomonas putida to generate a tailored, re-factored chassis with highly attractive new-to-nature properties, thereby opening the door to the production of thus far non-accessible compounds. This industrially driven project capitalises on the outstanding metabolic endowment and stress tolerance capabilities of this versatile bacterium for the production of spe ...
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 9

 TERMINÉ 

Embedding crop diversity and networking for local high quality food systems (DIVERSIFOOD)

Date du début: 1 mars 2015, Date de fin: 28 févr. 2019,

DIVERSIFOOD will evaluate and enrich the diversity of cultivated plants within diverse agroecosystems so as to increase their performance, resilience, quality and use through a multi-actor approach. By integrating existing experienced networks and using specific and relevant cases across Europe the project will strengthen “food culture” to improve economic viability of local chains resulting in a ...
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 21

 TERMINÉ 

UNDERSTANDING THE CLOSTRIDIUM SPORE, A PREREQUISTE FOR DISEASE INTERVENTIONS AND EXPLOITATION (CLOSPORE)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

Bacterial endospores are the most resistant life-forms on earth and the most important single feature of the genus Clostridium. Thus, whilst the pathogenesis of its notorious pathogens (C. botulinum, C. perfringens and C. difficile) is ascribed to the devastating toxins produced (neurotoxins, endotoxins and cytotoxins), it is their capacity to produce spores that lies at the heart of the diseases ...
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 8

 TERMINÉ 

Finding New Mechanisms for Protein Localization in Bacteria (ProteinLocalization)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2018,

During infection, the host immune system interacts with the bacterial cell surface, a complex structure made of peptidoglycan, wall teichoic acids, lipoteichoic acids, capsule polysaccharide and peptidoglycan-attached proteins. A lot is known about the metabolic pathways for the synthesis of each individual cell surface component. Almost nothing is known about the coordination between the synthesi ...
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 1

 TERMINÉ 

LEGumes for the Agriculture of TOmorrow (LEGATO)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2017,

The project has been conceived to promote the culture of grain legumes in Europe by identifying priority issues currently limiting grain legume cultivation and devising solutions in term of novel varietal development, culture practices, and food uses. LEGATO will develop tools and resources to enable state of the art breeding methodology and to exploit fully the breadth of genetic resources avail ...
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 32

 TERMINÉ 

Foreseeing Opportunities, Risks and Emergent Science Issues for the next Generation: Highlighting Trends (FORESIGHT)

Date du début: 1 juin 2016, Date de fin: 30 nov. 2017,

Our proposal for ERN 2016-17 is focussed on foresight, exploring alternatives to consider and manage the future with researchers and the public, envisioning new trends of science and technologies and of their impacts on society. Of special concern are the complex problems and challenges that humanity faces: climate change, sustainable energy, food and water supply, ageing and social inclusion, to ...
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 4

 TERMINÉ 

A stepping stone approach towards the Genetics Clinic of the Future (GCOF)

Date du début: 1 janv. 2015, Date de fin: 30 juin 2017,

The Genetics Clinic of the Future (GCOF) project aims to ensure that the clinical implementation of genome technologies is relevant and responsive to the needs of all. It offers a stepping stone approach towards the genetics clinic of the future, engaging all stakeholders involved in a process of mutual learning and information exchange. The GCOF project implements key Science with and for Society ...
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 13

 TERMINÉ 

Innovative Ionic polymers from Natural Sources for Energy&Environment (IONRUN)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

IONRUN (Innovative Ionic polymers from Natural Sources for Energy&Environment) International Research StaffScheme aims to stregthen research partnerships through staff exchanges and networking activities between threeEuropean Research organizations: University of the Basque Country (Spain), University Cergy-Pontoise (France) andUniversity Nova of Lisbon (Portugal) and five non-EU Research Organiza ...
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 4

 TERMINÉ 

Combining innovation in vineyard management and genetic diversity for a sustainable European viticulture (INNOVINE)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"The strategic goal of the project is to help the European vineyard sector facing the increasingly global competition by meeting:* Consumer demands for diversified high quality wines and concerns for food safety* Citizens’ requests for environment-friendly production systems involving decreased or no use of pesticides and spare of not renewable natural resources* Producers’ needs of plant material ...
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 29

 TERMINÉ 

3to4: Converting C3 to C4 photosynthesis for sustainable agriculture (3TO4)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

Most plants use the C3 pathway of photosynthesis that is compromised by gross inefficiencies in CO2 fixation. However, some plants use a super-charged photosynthetic mechanism called C4 photosynthesis. The C4 pathway is used by the most productive vegetation and crops on Earth. In addition to faster photosynthesis, C4 plants demand less water and less nitrogen. Overall, our aim is to introduce the ...
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 20

 TERMINÉ 

Transnational access and enhancement of integrated Biological Structure determination at synchrotron X-ray radiation facilities (BIOSTRUCT-X)

Date du début: 1 sept. 2011, Date de fin: 29 févr. 2016,

The BioStruct-X consortium has 19 partners from 11 EU member and associated states, who lead in facility provision and research in structural biology using high brilliance X-rays, provided by state-of-the art synchrotrons and a free electron laser. BioStruct-X will provide integrated transnational access via 42 installations in four key areas: macromolecular X-ray crystallography, small angle X-ra ...
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 20

 TERMINÉ 

Standarization and orthogonalization of the gene expression flow for robust engineering of NTN (new-to-nature) biological properties (ST-FLOW)

Date du début: 1 déc. 2011, Date de fin: 30 nov. 2015,

The ST-FLOW Project merges the efforts of 14 leading European research groups for developing material and computational standards that enable the forward-design of prokaryotic systems with a degree of robustness and predictability that is not possible with customary Genetic Engineering. The central issue at stake is the identification and implementation of rules that allow the conversion of given ...
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 15

 TERMINÉ 

Parliaments and Civil Society in Technology Assessment (PACITA)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2015,

The PACITA Mobilisation and Mutual Learning Action Plan will distribute capacity and enhance the institutional foundation for knowledge-based policy-making on issues involving science, technology and innovation, mainly based upon the practices in Parliamentary Technology Assessment (PTA). PTA supports the processes of democratic policy-making on issues involving science, technology and innovation, ...
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 16

 TERMINÉ 

Ion Transport at atomic level (ITrans)

Date du début: 1 août 2012, Date de fin: 31 janv. 2015,

Cell membranes provide compartmentalization and allow cells to keep their physical-chemistry balance. Ion transport across cell membranes is vital for life, establishing and maintaining a difference of electrochemical potential. From the biosynthesis of energy to the transport of solutes, ion transport is central to the energy transduction process.One of key players in the energy transduction pro ...
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 1

 TERMINÉ 

Biocluster Transnational du Sud-ouest européen (TRANSBIO SUDOE)

Date du début: 30 sept. 2012, Date de fin: 30 déc. 2014,

La spécialisation du territoire SUDOE dans le secteur de la bioéconomie peut améliorer la conjoncture actuelle de l'espace. C'est une activité qui favorise la compétitivité et la création d'emplois qualifiés liée à de multiples secteurs.À cet effet, le projet TRANSBIO SUDOE vise à répondre à cet objectif en transformant les résultats de la recherche en réalités économiques dans le cadre du domaine ...
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 9

 TERMINÉ 

Strategies for Organic and Low-input Integrated Breeding And Management (SOLIBAM)

Date du début: 1 mars 2010, Date de fin: 31 août 2014,

SOLIBAM will develop specific and novel breeding approaches integrated with management practices to improve the performance, quality, sustainability and stability of crops adapted to organic and low-input systems, in their diversity in Europe and taking into account small-scale farms in Africa. SOLIBAM will: 1. Identify traits specific for adaptation to low-input/organic conditions over a wide ran ...
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 24

 TERMINÉ 

ER Stress and Photoreceptor Degeneration in Drosophila (DROSOERSTRESS)

Date du début: 1 déc. 2008, Date de fin: 1 avr. 2014,

"The endoplasmic reticulum (ER) is the cell organelle where secretory and membrane proteins are synthesized and folded. The presence of unfolded/misfolded proteins in the ER causes stress to the cell (“ER stress”) and activates the Unfolded Protein Response (UPR), a cellular response to restore homeostasis in the ER. The presence of misfolded proteins and activation of the UPR have been connected ...
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 1

 TERMINÉ 

The role of Base Excision Repair (BER) for extreme radiation and desiccation resistance of Deinococcus radiodurans (BERinDR)

Date du début: 1 avr. 2012, Date de fin: 31 mars 2014,

...g radiation. The biological function of metal clusters in selected BER proteins will also be analysed by Electron Paramagnetic Resonance (EPR) and X-ray crystallography. The project will be hosted by Instituto de Technologia Química e Biológica (ITQB) at the Universidade Nova de Lisboa, Portugal, and will benefit immensely from the infrastructure and multidisciplinary expertise offered by this ins ...
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 1

 TERMINÉ 

How will life be in 2020? (Future2020)

Date du début: 1 mai 2013, Date de fin: 30 nov. 2013,

This proposal aims to raise awareness of the prominent role researchers and how their work plays in our currently every day and for the future. Bearing in mind Horizon 2020 Societal Challenges, the ERN2013 will promote and disseminate what in terms of science and innovation is being done in Portugal.The extensive and nationwide range of activities already planned and being prepared have one major ...
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 10

 TERMINÉ 

Crystallization in Ionic Liquid Solutions (CRYSTILS)

Date du début: 1 avr. 2010, Date de fin: 28 août 2013,

"Crystallization is an essential process in the manufacture of products as varied as pharmaceuticals, electronic devices or biomimetic materials. In order to obtain a crystalline product with desirable characteristics (e.g. crystal size, morphology, structural organization) for specific applications it is crucial to control the mechanism and kinetics of crystal nucleation and growth. Yet, our unde ...
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 1

 TERMINÉ 

Sustainable water use securing food production in dry areas of the Mediterranean region (SWUP-MED)

Date du début: 1 juil. 2008, Date de fin: 30 juin 2013,

"The strategic objective of the project is to improve food crop production in the Mediterranean region, influenced by multiple abiotic stresses. These stresses are becoming even more pronounced under changing climate, predicted to result in drier conditions, increasing temperatures, and greater variability, causing desertification. The project will work mainly in farmers’ communities to improve fa ...
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 9

 TERMINÉ 

Designing metallopeptides for the removal of superoxide radicals (MFRosPep)

Date du début: 1 avr. 2009, Date de fin: 31 mars 2013,

Oxidative stress results from an imbalance between the generation of reactive oxygen species and the antioxidant defense mechanisms. In recent years, oxidative stress has been implicated in a variety of detrimental health conditions including cardiovascular diseases, neurodegenerative disorders, and other types of age-related diseases. Evidence shows that the formation of superoxide radicals is a ...
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 1

 TERMINÉ 

Spatial organization and dynamics of Escherichia coli RNA degradation machinery (RNaseDYNAMICS)

Date du début: 1 sept. 2010, Date de fin: 31 août 2012,

The aim of this research proposal is to investigate in detail the location and mobility of RNA degradation machinery in E. coli. RNA decay has been widely studied in bacteria but continues to reveal subtle secrets [1,2]. Recent research demonstrates that the degradosome complex forms cytoskeletal-like structures linked with the inner cell membrane [3]. Preliminary results from Cecilia Arraiano’s l ...
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 1

 TERMINÉ 

Structure of Herpesviral cell access (SHerpA)

Date du début: 1 sept. 2010, Date de fin: 31 août 2012,

Membrane-bound proteins play several important roles in biological processes and viral infections make no exception. Especially for enveloped viruses, where the virion-mediated fusion with the target membrane starts the infection cycle and insights about the viral membrane proteins acting as fusion machineries provide targets for drug design. Human cytomegalovirus (HCMV, a member of the enveloped ...
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 1

 TERMINÉ 

New Halogenated Ionic Liquids as novel task-specific fluids (HALOGENILS)

Date du début: 1 sept. 2010, Date de fin: 31 août 2012,

"Organohalogen compounds are key materials in chemical, medicinal, agrochemical, and material sciences. They can also be used as basis for alternative reaction or extraction schemes due to their poor miscibility with both hydrocarbons and water. Hence, it is of great importance to develop environmentally benign selective halogenated systems. One of the key-issues concerning the current importance ...
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 1

 TERMINÉ 

A comprehensive dissection of pneumococcal-host interactions (PNEUMOPATH)

Date du début: 1 mars 2009, Date de fin: 31 août 2012,

"This project is a fundamental, comprehensive study of the host-pathogen interactions during infection with Streptococcus pneumoniae. The expectation is that the basic knowledge gained from this work will give new targets for vaccination, diagnosis and treatment. In PNEUMOPATH, academic and industrial partners will work together in six scientific workpackages. 1) The molecular epidemiology of anti ...
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 15

 TERMINÉ 

Structural Biology of Membrane Proteins (SBMPs)

Date du début: 1 sept. 2008, Date de fin: 31 août 2012,

Membrane proteins (MPs) are known to be key molecules in cellular communications, from signal transduction to transport of ions, metabolites and other molecules. They also participate in the synthesis of ATP, the import of soluble or MPs from the cytosol, and they protect living organisms from toxic factors. The proposal consists in a joint training effort involving the major biophysical methods t ...
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 12

 TERMINÉ 

CONtrol of COmmunity-acquired MRSA: Rationale and Development of counteractions (CONCORD)

Date du début: 1 janv. 2009, Date de fin: 30 juin 2012,

"Until recently, methicillin-resistant Staphylococcus aureus (MRSA) were confined to hospitals (HA-MRSA). However, community- and farm-associated MRSA (CA-and FA-MRSA) has developed as an important cause of infections. No strategies exist to combat these MRSA. CONCORD is aimed at explaining the ecological success in the community and the farm environment of CA- and FA-MRSA in contrast to HA-MRSA i ...
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 9

 TERMINÉ 

Translational Research on Combating Antimicrobial Resistance (TROCAR)

Date du début: 1 janv. 2009, Date de fin: 30 juin 2012,

"The health care systems of most European countries are based on a continuum from acute care hospitals, though other health care facilities to the community. Such a framework provides the perfect opportunity for the wide-spread dissemination of high-risk resistant clones or genetic resistant elements. The driving concept of TROCAR is to investigate the fundamentals of the epidemiology of new high ...
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 14

 TERMINÉ 

Analysis of the cellular function of type III secretion effectors of Chlamydia trachomatis (CHLTRT3SE)

Date du début: 1 janv. 2009, Date de fin: 31 déc. 2011,

"Chlamydiales are a large group of highly related obligate intracellular bacteria that includes the human pathogens Chlamydia trachomatis and Chlamydophila pneumoniae. C. trachomatis is an agent of genital and ocular infections, and Cph. pneumoniae causes atypical pneumonias. All Chlamydiae use a type III secretion (T3S) apparatus to translocate ~ 60-90 effector proteins into host cells. These eff ...
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 1

 TERMINÉ 

Approches interdisciplinaires et stratégies intégrées pour les sciences du vivant et leurs applications dans le Sud-ouest européen (INTERBIO)

Date du début: 30 avr. 2009, Date de fin: 30 déc. 2011,

El proyecto INTERBIO se plantea optimizar a escala transnacional las inversiones individuales realizadas en el espacio SUDOE en el campo de la biotecnología poniendo en red plataformas tecnológicas de alto nivel y facilitando la transferencia de los progresos innovadores hacia el sector industrial. Todos estos objetivos persiguen la consecución de los siguientes resultados: - Promoción de la inves ...
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 5

 TERMINÉ 

Setting the Stage in Portugal: researchers and the public come together through theatre (SettingTheStage)

Date du début: 1 mai 2009, Date de fin: 30 nov. 2009,

Through the medium of theatre and visual arts, SettingTheStage brings together research centres, universities, an SME, a science museum and theatre groups from four major cities in Portugal, to create multiple spaces where scientists and the public can actively engage in the reality of being a scientist and in the two big scientific celebrations of 2009: the 400th anniversary of Galileo's first us ...
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 9