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12 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 

ORTHOpedic randomized clinical trial with expanded bone marrow MSC and bioceramics versus autograft in long bone nonUNIONs (ORTHOUNION)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Current orthopaedic treatments permit spontaneous bone regeneration to unite and heal 90% bone injuries. Non-union associates pain and disability, often requiring biological enhancement. Regenerative medicine research suggests to the general public that alternative treatments based on advanced therapy medicinal products (ATMP) are already available. However, early clinical trials only explore its ...
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 13

 TERMINÉ 

Collaborative European NeuroTrauma Effectiveness Research in TBI (CENTER-TBI)

Date du début: 1 oct. 2013, Date de fin: 31 mars 2020,

Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 p ...
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 44

 TERMINÉ 

Standardization and Development of Assays for Assessment of Influenza Vaccines Correlates of Protection (FLUCOP)

Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,

Background: Influenza viruses cause annual epidemic and occasional pandemics, both of which induce significant morbidity and mortality. Influenza infections affect all age groups but children and adults over the age of 65 are at most risk of developing severe disease.Vaccination is the most effective approach to reduce the impact of annual influenza outbreaks and potential pandemics, however, the ...
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 26

 TERMINÉ 

Combatting Bacterial Resistance in Europe (COMBACTE-NET)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2019,

The emergence of Antibiotic-resistant bacteria (ARB) is a global problem, having recently been elevated to the top three threats identified by the World Health Organisation (WHO), and subject of numerous national and international government activities, including the Trans-Atlantic Task Force on Antimicrobial Resistance established by the US and EU presidencies. The estimated costs of ARB are aro ...
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 38

 TERMINÉ 

Production and characterization of endocrine cells derived from human pancreas organoids for the cell-based therapy of type 1 diabetes (LSFM4LIFE)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

Self-renew and multilineage potential characterize stem cells. We have recently described that pancreas progenitor cells extracted from adult donors can be expanded long-term in vitro into 3D structures, which we have termed organoids. Pancreas organoids reproduce in vitro all the features of pancreas ductal epithelia, and have a limitless expansion potential. Thus, pancreas organoids promise t ...
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 7

 TERMINÉ 

Multiple-actOrs Virtual Empathic CARgiver for the Elder (MoveCare)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

MoveCare develops and field tests an innovative multi-actor platform that supports the independent living of the elder at home by monitoring, assist and promoting activities to counteract decline and social exclusion. It comprises 3 hierarchical layers: 1) A service layer provides monitoring and intervention. It endows objects of everyday use with advanced processing capabilities and integrates th ...
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 14

 TERMINÉ 

Molecular Reclassification to Find Clinically Useful Biomarkers for Systemic Autoimmune Diseases (PRECISESADS)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2019,

We concur to the IMI on “Reclassification of SLE, connective tissue diseases and RA” call by presenting a proposal aimed at using the power of OMICs, and bioinformatics to identify new classifications for diseases known to share common pathophysiological mechanisms. Such knowledge has not been applied to individual patients, depriving them from potential benefits in terms of the use of new therape ...
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 30

 TERMINÉ 

An optical neuro-monitor of cerebral oxygen metabolism and blood flow for neonatology (BabyLux)

Date du début: 1 janv. 2014, Date de fin: 31 déc. 2016,

The BabyLux project aims to provide a precise, accurate and robust integrated system to continuously monitoring cerebral oxygen metabolism and blood flow in critically ill newborn babies. Over the last two decades, the percentage of preterm births in the Western hemisphere rose by 20%. During early stages of brain development, injury from lack of blood flow and oxygen delivery may induce cognitive ...
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 9

 TERMINÉ 

A Gateway to European Kidney Research Resources - KidneyConnect (KidneyConnect)

Date du début: 1 août 2013, Date de fin: 31 juil. 2016,

Diabetes, Cardiovascular and Chronic kidney (DCC) -diseases are relentlessly increasing globally, causing enormous human suffering, premature deaths and unsustainable costs. Leading European research has indisputably pointed that the kidney filtration barrier and its epithelial cell, the podocyte, is a common denominator for the DCC-diseases. However, European excellence and expertise have remaine ...
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 19

 TERMINÉ 

Regenerating Bone defects using New biomedical Engineering approaches (REBORNE)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2015,

Bone is among the most frequently transplanted tissue with about 1 million procedures annually in Europe. The worldwide market of bone replacement materials is currently estimated at 5 billion € with a 10% annual growth. Despite their considerable disadvantages, including the risk of disease transfer and immunologic rejection, limited supply of bone, costs and complications, allografts and autogra ...
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 24

 TERMINÉ 

Active Constraints Technologies for Ill-defined or Volatile Environments (ACTIVE)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2015,

Description Active Constraints Technologies in Neurosurgery for Ill-defined or Volatile Environments The ACTIVE project exploits ICT and other engineering methods and technologies for the design and development of an integrated redundant robotic platform for neurosurgery. A light and agile redunda ...
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 19

 TERMINÉ 

Cultivated Adult Stem Cells as Alternative for Damaged tissue (CASCADE)

Date du début: 1 janv. 2009, Date de fin: 31 déc. 2011,

"Rapid progress in stem cell research pave the way for the development and use of new cell therapy products in regenerative medicine. The objective of CASCADE is to provide the European Community with unique expertise which focuses on the GMP production of mesenchymal stem cells (MSC) and their use in treating skin and corneal wounds, so that quality and safety criteria are paramount and match the ...
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 16