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4 projets européens trouvés

Recherche sur 125080 projets européens

 TERMINÉ 
NanoAthero aims to have demonstration of initial clinical feasibility of nanosystems for targeted imaging and treatment of advanced atherosclerotic disease in humans. The nanosystems are assemblies of following components: nanocarrier, targeting, imaging agent/drug. They have proven safety records, and strong preliminary in vitro and in vivo proofs of efficacy are available. Partners have patented ...
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 17

 TERMINÉ 
...11 PET, possibly with other IBs introduced later. The project will be delivered using a portfolio of animal (WP2), human (WP3), image analysis (WP4) and regulatory (WP5) work. The project will be coordinated and the interdependent workpackages integrated in WP1. These WPs will deliver image acquisition and analysis protocols which are technically valid, standardised and suitable for multicentre us ...
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 26

 TERMINÉ 

APL a model for oncogene-targeted leukemia cure (STEMAPL)

Date du début: 1 juil. 2011, Date de fin: 30 juin 2017,

"Acute promyelocytic leukaemia, APL, is probably one of the best-understood malignancies and the only one where highly efficient oncogene-targeted therapies (retinoic acid and arsenic) actually cure the disease. Our recent studies have addressed the molecular basis for transformation and demonstrated the essential role of sumoylation of the PML moiety of PML/RARA, relaxed DNA-binding specificity, ...
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 2

 TERMINÉ 
"According to the European Society of Cardiology there has been an increase in the life expectancy at the age of 65 of the European population from 15.0 to 17.0 years in the years since 1980. In the elderly, up to 50% of deaths are caused by cardiovascular diseases, the majority accounted for by coronary artery disease. The most effective treatment for obstructive coronary disease is percutaneous ...
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 16