8 projets européens trouvés
Recherche sur 125080 projets européens
TERMINÉ
TRANSlating the role of Mitochondria in Tumorigenesis (TRANSMIT)
Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,
The consolidation of the knowledge that cancer is not only a genetic, but also a metabolic disease, has led scientists to investigate the intricate metabolic plasticity that transformed cells must undergo to survive the adverse tumor microenvironment conditions, and the contribution of oncogenes and tumor suppressors in shaping metabolism. In this scenario, genetic, biochemical and clinical eviden ...
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10
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TERMINÉ
Systems Biology to Identify Molecular Targets for Vascular Disease Treatment (SYSVASC)
Date du début: 1 févr. 2014, Date de fin: 31 janv. 2018,
Asymptomatic vascular damage accumulates for years before patients are identified and subjected to therapeutic measures. The limited knowledge on early vascular disease pathophysiology is reflected in the lack of therapeutic options. SysVasc aims to overcome this limitation by mounting a comprehensive systems medicine approach to elucidate pathological mechanisms, which will yield molecular target ...
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19
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TERMINÉ
Impact of Prenatal Stress on BRAIN AGEing (BRAINAGE)
Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,
Healthy brain ageing is a major determinant of quality life-long health, allowing integration into society at all ages. Human epidemiological and animal studies indicate that in addition to life style and genetic factors, environmental influences in prenatal life have a major impact on brain ageing and age-associated brain disorders. We hypothesize that: (1) prenatal stress programs early brain ag ...
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10
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TERMINÉ
Application of new technologies and methods in nutrition research – the example of phenotypic flexibility (NutriTech)
Date du début: 1 janv. 2012, Date de fin: 30 juin 2016,
NutriTech will build on the foundations of traditional human nutrition research using cutting-edge analytical technologies and methods to comprehensively evaluate the diet-health relationship and critically assess their usefulness for the future of nutrition research and human well-being. Technologies include genomics, transcriptomics, proteomics, metabolomics, laser scanning cytometry, NMR based ...
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25
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TERMINÉ
Biomarker for Cardiovascular Risk Assessment in Europe (BiomarCaRE)
Date du début: 1 oct. 2011, Date de fin: 31 mars 2016,
Biomarkers are considered as tools to enhance cardiovascular risk estimation. However, the value of biomarkers on risk estimation beyond European risk scores, their comparative impact among different European regions and their role in the drive towards personalised medicine remains uncertain.Based on harmonised and standardised European population cohorts we have built significant research collabo ...
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31
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TERMINÉ
Integrated technologies for the discovery and development of cosmeceutical agents from plant biodiversity (NATPROTEC)
Date du début: 1 févr. 2012, Date de fin: 31 janv. 2016,
"NATPROTEC aims to discover and carry to the stage of development innovative products in the area of cosmeceuticals originating from European natural resources using emerging and environmentally friendly technologies. These objectives will be implemented through an extended and balanced scheme of researcher’s exchanges and recruitments, in both directions and via a mutual scientific project develo ...
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9
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TERMINÉ
Systems biology towards novel chronic kidney disease diagnosis and treatment (SysKID)
Date du début: 1 janv. 2010, Date de fin: 31 déc. 2014,
Chronic kidney disease (CKD) affects up to 10% of the population. Besides eventual progression towards end stage renal disease CKD impacts the patient’s quality of life by causing serious comorbidities including cardiovascular complications and bone metabolism disorders. On the everyday clinical level early stage diagnosis and tailored treatment of CKD are still inadequate. In addition, CKD seems ...
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30
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TERMINÉ
Metabolic Flux Analysis and Cancer (METAFLUX)
Date du début: 1 nov. 2010, Date de fin: 31 oct. 2014,
"The post-genomic era has been driven by the development of technologies that allow the function of cells and whole organisms to be explored at a molecular level. Metabolomics is concerned with the measurement of global sets of low-molecular-weight metabolites, which represent important indicators of physiological or pathological states of organisms. Such profiles provide a more comprehensive view ...
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