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Plus de 40 projets européens trouvés

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 TERMINÉ 

Metal Transport in the Environment (MetTrans)

Date du début: 1 févr. 2012, Date de fin: 31 juil. 2016,

Understanding the processes that control the transport of metals in the environment is essential for a wide range of fields, including environmental protection and remediation, mineral resources, climate change. Through recent analytical developments, it is possible, using natural variations in metal isotopes, to identify and quantify how metal concentrations in natural waters are controlled by in ...
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 10

 TERMINÉ 

Prediction of cognitive properties of new drug candidates for neurodegenerative diseases in the early clinical development (PHARMA-COG)

Date du début: 1 janv. 2010, Date de fin: 31 déc. 2015,

PHARMA-COG aims to develop a new integrated model to accelerate the development of drug cindidates for MS, PKD and AD. The innovation relies on a 'multidimensional matrix' approach, integrating all available and renewed inputs (biomarkers/animal, human models/physiological and pharmcological challenges, Phase 0/1/1b to reduce the attrition rate, to allow an early and pertinent GO/NOGO decision bef ...
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 38

 TERMINÉ 

Targeting Src-family tyrosine kinases in chronic autoimmune and inflammatory diseases (TARKINAID)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2015,

The project aims to develop novel inhibitors of chronic autoimmune and inflammatory diseases by targeting members of the Src tyrosine kinase family. Src-family kinases have recently emerged as major therapeutic targets in malignant diseases but their suitability as potential targets of inflammatory diseases has not yet recieved widespread acceptance. On the other hand, members of the applicant con ...
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 11

 TERMINÉ 

MOLECULAR MECHANISMS OF AUTOPHAGY REGULATION IN TUBERCULOSIS (AUTOPHAGTUBERCULOSIS)

Date du début: 1 août 2011, Date de fin: 31 juil. 2015,

Mycobacterium tuberculosis (M.tb), etiologic agent of tuberculosis (TB), is still the leading cause of mortality by single bacterial infection worldwide. Annually, these air-borne bacilli kill almost 2 million people around the globe. M.tb is an extremely successful pathogen that have developed several strategies to neutralize the host immune defenses. One of significance is the block of phagosome ...
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 1

 TERMINÉ 

Integrated Medium for Planetary Exploration (IMPEX)

Date du début: 1 juin 2011, Date de fin: 31 mai 2015,

IMPEx (Integrated Medium for Planetary Exploration) is aimed at creation of an interactive framework where data from planetary missions will be interconnected with numerical models providing a possibility 1) to simulate planetary phenomena and interpret space missions measurements; 2) to test models versus experimental data and perform further improvement of models; 3) to fill gaps in the measurem ...
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 5

 TERMINÉ 

A new vision on nanocatalysts (NANOSONWINGS)

Date du début: 1 avr. 2010, Date de fin: 31 mars 2015,

In recent years it has been recognized that small metal nanoparticles hold the promise that their catalytic properties may be completely different from those of their bulk analogs or their monometallic complexes. Entirely new chemical conversions may be expected because of their shape and thermodynamic properties. So far, this promise has not led to important breakthroughs, as most findings can be ...
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 2

 TERMINÉ 

Distributed Research Infrastructure for Hydro-Meteorology (DRIHM)

Date du début: 1 sept. 2011, Date de fin: 28 févr. 2015,

Predicting weather and climate and its impacts on the environment, including hazards such as floods and landslides, is still one of the main challenges of the 21st century, with significant societal and economic implications. At the heart of this challenge, as also suggested by the DRIHMS (Distributed Research Infrastructure for Hydro-Meteorology Study) project, lies the ability to have easy acce ...
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 12

 TERMINÉ 

Innovative End-to-end Management of Dynamic Manufacturing Networks (IMAGINE)

Date du début: 1 sept. 2011, Date de fin: 31 déc. 2014,

Effective end-to-end management of dynamic manufacturing networks is consistently touted as a top priority for manufacturing enterprises that need to strive to improve their efficiency, adaptability and sustainability of their production systems. Moreover, it is a crucial prerequisite for the emerging powerful new model of production based on community, collaboration, and self-organisation and ope ...
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 15

 TERMINÉ 

Creation of a distributed European Magnetic Field Laboratory (EMFL)

Date du début: 1 janv. 2011, Date de fin: 31 déc. 2014,

The Radboud University Nijmegen, operating the High Field Magnet laboratory (HFML, for continuous magnetic fields), the Forschungszentrum Dresden-Rossendorf, operating the Hochfeld-Magnetlabor Dresden (HLD, for pulsed magnetic fields), and the Conseil National de la Recherche Scientifique, operating the Laboratoire National de Champs Magnétiques Intenses in Grenoble and Toulouse (LNCMI-G for conti ...
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 3

 TERMINÉ 

European Network for Social Intelligence (SINTELNET)

Date du début: 1 juin 2011, Date de fin: 31 déc. 2014,

SINTELNET is a Coordination Action whose aim is to explore the interplay of future and emerging information technologies and the development of Philosophy, Humanities and the Social Sciences. Advances in science and IT are rapidly creating and sustaining new forms of perception, communication and social interaction. The traditional distinctions between the natural, the social and the artificial ar ...
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 7

 TERMINÉ 

"Food Refrigeration Innovations for Safety, consumer Benefit, Environmental impact and Energy optimization along cold chain in Europe" (FRISBEE)

Date du début: 1 sept. 2010, Date de fin: 31 août 2014,

"The objective of the FRISBEE (Food Refrigeration Innovations for Safety, consumers’ Benefit, Environmental impact and Energy optimisation along the cold chain in Europe) project is to provide new tools, concepts and solutions for improving refrigeration technologies along the European food cold chain. At all stages the needs of consumer and European industry will be considered.The project will de ...
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 26

 TERMINÉ 

Innovative Synthesis in Continuous-Flow Processes for Sustainable Chemical Production (SYNFLOW)

Date du début: 1 sept. 2010, Date de fin: 31 août 2014,

The SYNFLOW vision is the paradigm shift from batch-wise large volume processes in pharmaceuticals, fine chemicals and intermediates production comprising many separate unit operations towards highly integrated but yet flexible catalytic continuous flow processing. For this purpose, SYNFLOW develops a unique integrative approach combining molecular understanding of synthesis and catalysis with eng ...
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 23

 TERMINÉ 

Securing the Conservation of biodiversity across Administrative Levels and spatial, temporal, and Ecological Scales (SCALES)

Date du début: 1 mai 2009, Date de fin: 31 juil. 2014,

Our capacity to effectively sustain biodiversity across spatial and temporal scales is an essential component of European environmental sustainability. Anthropogenic and environmental pressures on biodiversity act differently at different scales. Consequently, effective conservation responses to these threats must explicitly consider the scale at which effects occur, and therefore it is crucial th ...
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 31

 TERMINÉ 

METABOLIC CONTROL OF IMMATURE STROMAL CELL BIOLOGY (METABOSTEM)

Date du début: 1 août 2011, Date de fin: 31 juil. 2014,

"A very recent literature claims that metabolic status represents a crucial regulatory mechanism that helps direct stem cells fate. Whereas mainly described on the well characterized hematopoietic stem cells population, such metabolic investigations have been poorly conducted on another key population of adult immature cells that populate the stromal compartment of all tissues, i.e. the mesenchyma ...
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 1

 TERMINÉ 

ADIPOSE DERIVED STROMAL CELLS FOR OSTEOARTHRITIS (ADIPOA)

Date du début: 1 janv. 2010, Date de fin: 30 juin 2014,

Osteoarthritis (OA) is a degenerative joint disease for which no efficient therapy is available. The ADIPOA consortium has previously shown that intraarticular injections of stromal cells prevents OA in two different models, but the mechanisms of this chondroprotective effect remains unknown, and the activation of cartilage derived endogenous stem cells is suspected. The participants have experien ...
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 12

 TERMINÉ 

Adaptive Strategies to Mitigate the Impacts of Climate Change on European Freshwater Ecosystems (REFRESH)

Date du début: 1 févr. 2010, Date de fin: 31 janv. 2014,

Understanding how freshwater ecosystems will respond to future climate change is essential for the development of policies and implementation strategies needed to protect aquatic and riparian ecosystems. The future status of freshwater ecosystems is however, also dependent on changes in land-use, pollution loading and water demand. In addition the measures that need to be taken to restore freshwat ...
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 26

 TERMINÉ 

Advanced TEchnology MOdelling for eXtra-functionality devices (ATEMOX)

Date du début: 1 juil. 2010, Date de fin: 30 nov. 2013,

Description Extends the capabilities of TCAD to the modelling of leakage currents and technologies for low-leakage ultra-shallow junctions.Within previous European projects process simulation has been brought to a state which allows in industrial environments a sufficiently accurate simulation of doping profiles in advanced CMOS technolog ...
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 14

 TERMINÉ 

Initial training network on biocorrosion (BIOCOR ITN)

Date du début: 1 sept. 2009, Date de fin: 31 août 2013,

"Any material in contact with water or moisture during its life-cycle is rapidly colonised by microbial species which can be the source of severe deterioration processes, such as microbially influenced corrosion (MIC), also called biocorrosion. The annual direct and derived costs of corrosion are estimated to be around 4% of the GNP of developed countries, of which 10-20% are related to biocorrosi ...
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 10

 TERMINÉ 

International sensor development network (SENSEnet)

Date du début: 1 juin 2009, Date de fin: 31 mai 2013,

This ITN project will train young investigators to enable them make significant advances in the field of in situ sensor technology. It will bring together 15 research groups and 2 industrial partners from across the European Union. The ITN will provide training for 16 PhD students, early stage researchers (ESRs) and 1 Postdoctoral student, experienced researcher (ER). The programme will combine th ...
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 11

 TERMINÉ 

Monitoring and Assessing Regional Climate change in High latitudes and the Arctic (MONARCH-A)

Date du début: 1 mars 2010, Date de fin: 31 mai 2013,

"By adopting an Earth system approach the ultimate goal of MONARCH-A is to generate a dedicated information package tailored to a subset of multidisciplinary Essential Climate Variables and their mutual forcing and feedback mechanisms associated with changes in terrestrial carbon and water fluxes, sea level and ocean circulation and the marine carbon cycle in the high latitude and Arctic regions. ...
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 8

 TERMINÉ 

Physiological impact of IF1 inhibitor on Reverse Cholesterol Transport (RCT) and atherosclerosis (CardIF)

Date du début: 1 juin 2011, Date de fin: 31 mai 2013,

Several large prospective studies established that high-density lipoprotein cholesterol (HDL-C) is an independent negative risk factor for CHD thus representing today’s major protective factor against atherosclerosis, mostly attributable to their roles in ‘Reverse Cholesterol Transport (RCT)’. RCT allows excessive cell cholesterol to be taken up and processed in HDL particles, and later carried to ...
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 1

 TERMINÉ 

New pincer-type complexes derived from 2-indenylidene ligands (INDEN)

Date du début: 1 mars 2011, Date de fin: 28 févr. 2013,

"The group of D. Bourissou has recently reported a new family of indenyl-type ligands bearing one or two coordinating side-arms. These new ligands have allowed the preparation of several metal complexes (Zr, Rh, Pd) exhibiting original coordination modes: eta-1 indenyl and 2-indenylidene. In this project, we envision to take advantage of the strong sigma-donor character of such original 2-indenyli ...
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 1

 TERMINÉ 

MicroRNAs and Cancer: From Bench to Bedside (ONCOMIRS)

Date du début: 1 févr. 2008, Date de fin: 31 janv. 2013,

"Although studies addressing their role in cancer pathogenesis are at an early stage, it is apparent that specific microRNAs (miRs) and molecules involved in their biogenesis contribute to tumorigenesis. The ONCOMIRS consortium proposes a natural succession of four experimental strategies. Fist, we will DISCOVER and unveil novel miRs and components of their biogenesis machinery and investigate lin ...
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 8

 TERMINÉ 

Spatially-Implicit Modelling of Plankton Ecosystems (SIMPLE)

Date du début: 1 déc. 2010, Date de fin: 30 nov. 2012,

"The aim of SIMPLE is to investigate and parameterise the influence of small-scale spatial variability in plankton concentrations on the behaviour of large-scale mean fields. This is necessary for accurate plankton ecosystem models as biogeochemical subunits of predictive climate models, which must account for the influence of plankton ecosystems on the biosphere, and as tools to predict the large ...
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 1

 TERMINÉ 

Developing robots' social skills to support human-robot joint action execution (SKILLS4HRI)

Date du début: 1 nov. 2009, Date de fin: 31 oct. 2012,

"One major challenge in robotics research is to develop robots able to operate and help humans in everyday life. Personal robots are an emerging technology with a significant potential across broad applications (eldercare, healthcare, education, etc). However, for acting in a human world, acting for, with, or in contact of humans, we need to provide the robot with the abilities not only to act but ...
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 1

 TERMINÉ 

Carbon Nanotube Confinement Strategies to Develop Novel Polymer Matrix Composites (POCO)

Date du début: 1 nov. 2008, Date de fin: 31 oct. 2012,

Light composite materials for load bearing applications can be made using different type reinforcements and polymer matrices. Carbon nanotubes (CNT) have been studied extensively because of their exceptional mechanical and electrical properties, yet their practical and extensive use in commercial materials is missing. The utilization of CNTs as reinforcement to design novel composites is a quite o ...
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 17

 TERMINÉ 

Actinide reCycling by SEParation and Transmutation (ACSEPT)

Date du début: 1 mars 2008, Date de fin: 30 sept. 2012,

"Actinide recycling by separation and transmutation is considered worldwide and particularly in several European countries as one of the most promising strategies to reduce the inventory of radioactive waste, thus contributing to make nuclear energy sustainable. Consistently with potentially viable recycling strategies, the Collaborative Project ACSEPT will provide a structured R&D framework to de ...
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 35

 TERMINÉ 

A comprehensive dissection of pneumococcal-host interactions (PNEUMOPATH)

Date du début: 1 mars 2009, Date de fin: 31 août 2012,

"This project is a fundamental, comprehensive study of the host-pathogen interactions during infection with Streptococcus pneumoniae. The expectation is that the basic knowledge gained from this work will give new targets for vaccination, diagnosis and treatment. In PNEUMOPATH, academic and industrial partners will work together in six scientific workpackages. 1) The molecular epidemiology of anti ...
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 15

 TERMINÉ 

Mechanisms of Mineral Replacement Reactions (Delta-Min)

Date du début: 1 sept. 2008, Date de fin: 31 août 2012,

In this ITN we investigate the mechanism of mineral reequilibration (phase transformation) in the presence of a fluid phase in a wide range of minerals and rocks, under a range of chemical and physical conditions, using both natural and experimental samples. Interface-coupled dissolution-reprecipitation is a recently defined mechanism which applies to a wide range of mineral transformation phenome ...
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 9

 TERMINÉ 

Structural Biology of Membrane Proteins (SBMPs)

Date du début: 1 sept. 2008, Date de fin: 31 août 2012,

Membrane proteins (MPs) are known to be key molecules in cellular communications, from signal transduction to transport of ions, metabolites and other molecules. They also participate in the synthesis of ATP, the import of soluble or MPs from the cytosol, and they protect living organisms from toxic factors. The proposal consists in a joint training effort involving the major biophysical methods t ...
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 12

 TERMINÉ 

Cooperative Human Robot Interaction Systems (CHRIS)

Date du début: 1 mars 2008, Date de fin: 29 févr. 2012,

Description Developing technology for safe cooperative physical interaction with humans in a co-located space It is beneficial to our socio-economic welfare to generate service robots capable of safe co-operative physical interaction with humans. CHRIS addresses the fundamental issues which enable ...
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 7

 TERMINÉ 

DEXterous and autonomous dual-arm/hand robotic manipulation\nwith sMART sensory-motor skills: A bridge from natural to artificial cognition (DEXMART)

Date du début: 1 févr. 2008, Date de fin: 31 janv. 2012,

Description Dual-arm robot including two multi-fingered redundant hands to grasp and manipulate the same objects used by human beings The DEXMART project is focused on artificial systems reproducing human skills, which operate in unstructured real-world environments. The goal is to allow a dual-ar ...
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 9

 TERMINÉ 

Nano-scale ICT Devices and Systems Coordination Action (NanoICT)

Date du début: 1 janv. 2008, Date de fin: 31 déc. 2011,

In the semiconductor industry, CMOS technology will certainly continue to have a predominant market position in the future. However, there are still a number of technological challenges, which have to be tackled if CMOS downscaling should be pursued until feature sizes will reach 10 nm around the year 2015-2020.The NanoICT Coordination Action activities will reinforce and support the whole Europea ...
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 13

 TERMINÉ 

Experimental COgnitive Distributed Engine (ECODE)

Date du début: 1 sept. 2008, Date de fin: 31 déc. 2011,

The aim of the ECODE proposal is to develop, implement and validate experimentally a cognitive routing system. This system will use cognitive techniques to provide a routing system able to meet the future Internet challenges. The project gathers networking and machine learning experts to address these challenges efficiently. In architectural phase one, the cognitive routing system is designed and ...
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 8

 TERMINÉ 

Cultivated Adult Stem Cells as Alternative for Damaged tissue (CASCADE)

Date du début: 1 janv. 2009, Date de fin: 31 déc. 2011,

"Rapid progress in stem cell research pave the way for the development and use of new cell therapy products in regenerative medicine. The objective of CASCADE is to provide the European Community with unique expertise which focuses on the GMP production of mesenchymal stem cells (MSC) and their use in treating skin and corneal wounds, so that quality and safety criteria are paramount and match the ...
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 16

 TERMINÉ 

COmmunity heavy-PAyload Long endurance Instrumented Aircraft for Tropospheric Research in Environmental and Geo-Sciences (COPAL)

Date du début: 1 nov. 2007, Date de fin: 31 oct. 2011,

COPAL has the objective of providing the European scientific community with an unique research aircraft platform, capable of reaching and operating in any remote area in the world and offering a heavy-payload for integration of a large panoply of instruments for research in environmental and Geo-sciences. It will offer an unprecedented opportunity to countries that are not yet operating research a ...
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 13

 TERMINÉ 

LATENT TUBERCULOSIS: New tools for the detection and clearance of dormant Mycobacterium tuberculosis (STOPLATENT-TB)

Date du début: 1 févr. 2008, Date de fin: 31 juil. 2011,

Although the definition of latency under a clinical point of view seems clear, the bacterial biology behind that clinical situation remains poorly understood. While dormant, the tubercle bacilli are considered to be under non-replicating (NR) stage. In such a condition, bacilli are not only difficult to be detected but also refractory to the standard treatments avoiding their clearance from the in ...
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 7

 TERMINÉ 

Toward new polymeric materials by metal-mediated controlled radical polymerization (METMED-CRP)

Date du début: 1 juin 2009, Date de fin: 31 mai 2011,

"Controlled radical polymerization has revolutionized polymer research and has already started to revolutionize the polymer industry as previously unthinkable and complex polymer architectures are becoming available. However, access to a wider variety of polymer material is limited by the inability (so far) to control the radical polymerization of nucleophilic monomers. The host team is a world le ...
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 1

 TERMINÉ 

Mycobacterium tuberculosis W-Beijing genetic diversity and differential virulence and host immune responses (TB-VIR)

Date du début: 1 avr. 2008, Date de fin: 31 mars 2011,

"Improvements in TB control require the development of new tools for rapid and accurate diagnosis and intervention. This development is likely to benefit from more detailed knowledge of microbe-host relationships during infection. Following M. tuberculosis infection, only 5-10% of immunocompetent individuals develop TB. It is increasingly thought that the virulence of the infecting strain, togethe ...
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 11

 TERMINÉ 

Understanding the role of transition metals in Alzheimer's disease on a molecular level (MetAlzComp)

Date du début: 1 oct. 2009, Date de fin: 30 sept. 2010,

The aggregation of the amyloid-beta peptide (A-beta) into fibrils and successively in plaques is the main event in Alzheimer's disease. The A-beta originates from a membrane protein called amyloid-precursor protein. In healthy brain A-beta is present as soluble form and the predominant chains are formed by 40 or 42 amino acids. The oligomers of A-beta, rather then fully formed fibrils, are suspect ...
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 2