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 TERMINÉ 

European Sudden Cardiac Arrest network: towards Prevention, Education and NEw Treatment (ESCAPE-NET)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

Sudden cardiac arrest (SCA) causes ~20% of all deaths in Europe. SCA is lethal within minutes if left untreated and survival rates are presently only 5-20%. Therefore, there is a large medical need to improve SCA prevention and treatment. Designing effective individualized prevention and treatment strategies requires knowledge on genetic and environmental risk factors. So far, these efforts have b...
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 17

 TERMINÉ 

Nanomedicine for Drug Delivery

Date du début: 1 oct. 2016, Date de fin: 30 oct. 2021,

NANOMEDNanomedicine for Drug DeliveryCourses Description: This 24 months, 120 ECTS Master’s Course in English offers a high quality and multidisciplinary education in the emerging field of NANOMEDICINE. The consortium is composed of four Universities: Paris-Descartes (Fr, coordinator), Patras (Gr), Pavia (It) and Angers (Fr).Nanomedicine is a revolutionary interdisciplinary science, combining know...
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 4

 TERMINÉ 

Podocyte Adaptation Proliferation and Ageing (PAPAstudy)

Date du début: 1 mars 2016, Date de fin: 28 févr. 2021,

My research project is focused on the biology of the podocyte during chronic kidney disease progression, one of the major public health challenges of the 21st Century. The podocyte is a highly specialized cell with foot processes expansion that function as vasculature-supporting cells, producing basement membrane components and a number of vascular growth factors. These cells play an essential rol...
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 1

 TERMINÉ 

A Phase Ib/II study of MEK1/2 inhibitor PD-0325901 or MEK-162 with cMET inhibitor PF-02341066 in RASMT and RASWT (with aberrant c-MET) Colorectal Cancer Patients (MERCURIC)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2020,

Colorectal cancer (CRC) is the 3rd most common cancer in Europe, and with approximately 200,000 deaths per year, it remains the 2nd most common cause of cancer death. More than half of all CRC patients develop distant metastases and have 5-year overall survival (OS) of less than 5% because of ineffective treatments. Increased understanding of cancer biology, coupled with the implementation of “omi...
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 13

 TERMINÉ 

Goal-based Open-ended Autonomous Learning Robots (GOAL-Robots)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2020,

This project aims to develop a new paradigm to build open-ended learning robots called `Goal-based Open-ended Autonomous Learning' (GOAL). GOAL rests upon two key insights. First, to exhibit an autonomous open-ended learning process, robots should be able to self-generate goals, and hence tasks to practice. Second, new learning algorithms can leverage self-generated goals to dramatically accelerat...
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 5

 TERMINÉ 

Exploitation of aromatic plants’ by-products for the development of novel cosmeceuticals and food supplements. (EXANDAS)

Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,

‘EXANDAS’ project aims to apply emerging and cutting edge technologies in the field of Natural Product Chemistry in order to fully and efficiently exploit the therapeutic potential of medicinal and aromatic processing waste and by-products. New opportunities for the generation of innovative products with high added value in the field of cosmeceuticals and food supplements are expected to be gener...
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 9

 TERMINÉ 

Methods in Research on Research (MIROR)

Date du début: 1 mars 2016, Date de fin: 29 févr. 2020,

Our aim is to create, in Europe, an innovative and ambitious multidisciplinary intersectoral joint doctoral training programme, dedicated to Methods in Research on Research (MIROR) in the field of clinical research. “Research on Research”, is an emerging new scientific discipline that aims to reduce waste in research and increase research value. Waste in research represents tens of billions of Eur...
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 7

 TERMINÉ 

Paediatric Inflammatory Bowel Diseases Network for Safety, Efficacy, Treatment and Quality improvement of care (PIBD-SETQuality)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

"The incidence of paediatric onset Inflammatory Bowel Diseases (PIBD) has risen dramatically in recent decades. Compared to adult forms, PIBD reflects a more severe disease, more often requiring aggressive treatment with immunomodulators, and thereby exposing children to a life-long risk of serious disease and treatment-related adverse events, such as infections and malignancies. Therefore, there ...
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 12

 TERMINÉ 

Risk assessment of plaque rupture and future cardiovascular events (CVENT) by multi-spectral photoacoustic imaging (CVENT)

Date du début: 1 nov. 2016, Date de fin: 31 oct. 2019,

Cardiovascular disease (CVD), more specifically, vulnerable plaque rupture, remains the major cause of death for people at middle age. The CVENT consortium will revolutionize screening, diagnosis and monitoring of CVD by means of a compact photoacoustic imaging (PAI) system for vulnerable plaque imaging.In the carotid arteries feeding the brain, vulnerable plaque rupture initiates cerebrovascular ...
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 10

 TERMINÉ 

Infectious Diseases teaching Europe/Africa Learning

Date du début: 1 sept. 2016, Date de fin: 31 août 2019,

ObjectivesIDEAL project will develop a joint international curriculum in Infectious Diseases in English for European undergraduate students and African students from Uganda. ContextCurrent worldwide spreading of multi-resistant bacteria, along with major recent outbreaks and massive immigration underline the need for strong updated skills in the field for all physicians involved in patients’ care....
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 6

 TERMINÉ 

Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies (SPRINTT)

Date du début: 1 juil. 2014, Date de fin: 30 juin 2019,

The current healthcare systems are built around the traditional paradigm of patients suffering from a single acute illness. They are therefore largely unprepared to face the increasing demands for health services arising from the expansion of an older population with specific medical needs related to multiple chronic disorders. As a consequence, the medical conditions of a large and growing seg...
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 27

 TERMINÉ 

Doing It Together science (DITOs) (DITOs)

Date du début: 1 juin 2016, Date de fin: 31 mai 2019,

Our project, 'Doing-It-Together Science', DITOs, represents a step change in European public engagement with science and innovation. We propose moving from a model in which scientific research, innovation, and problem-solving is mainly driven by scientific/professional institutions to one based on active public participation and capacity building with various levels and strategies of engagement in...
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 11

 TERMINÉ 

Understanding and predicting developmental language abilities anddisorders in multilingual Europe (PREDICTABLE)

Date du début: 1 mars 2015, Date de fin: 28 févr. 2019,

PredictAble aims to train a new generation of young scientists at the crossroads between academic research, technological development in the private sector and clinical practice to pioneer an interdisciplinary approach to language related developmental disorders, like specific language impairment (SLI) and developmental dyslexia (DD). The innovative and timely research program will enhance the und...
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 6

 TERMINÉ 

Health and Environment-wide Associations based on Large population Surveys (HEALS)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2018,

Assessing individual exposure to environmental stressors and predicting health outcomes implies that both environmental exposures and epi/genetic variations are reliably measured simultaneously. HEALS (Health and Environment-wide Associations based on Large population Surveys) brings together in an innovative approach a comprehensive array of novel technologies, data analysis and modeling tools th...
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 37

 TERMINÉ 

La simulation en santé pour développer un partenariat entre apprenants et professionnels dans la formation médicale et paramédicale

Date du début: 1 sept. 2015, Date de fin: 31 août 2018,

Resorting to simulation in health has become common use in hospital and training centres. Currently, we observe compartmentalisation in its use in various fields (everyone works with their own objectives) and a lack of tools to assess the impact of the simulation in learning skills required for an optimal care of the patients. This project proposes to work on two original approaches. Firstly, it p...
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 6

 TERMINÉ 

"A new approach to understanding consciousness: how ""feel"" arises in humans and (possibly) robots." (FEEL)

Date du début: 1 juin 2013, Date de fin: 31 mai 2018,

"Philosophers divide the problem of consciousness into two parts: An “easy” part, which involves explaining how one can become aware of something in the sense of being able to make use of it in one's rational behavior. And a “hard” part, which involves explaining why certain types of brain activity should actually give rise to feels: for example the feel of ""red"" or of ""onion flavor"". The ""ha...
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 1

 TERMINÉ 

Biomarkers of renal graft injuries in kidney allograft recipients (BIOMARGIN)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2018,

In renal allograft recipients, 10-year graft survival has not improved over the past decades. Histological examination of graft biopsies has long been the gold standard to confirm graft injuries, but biopsies are invasive and histological grading is not very robust. There is thus a need for robust, non-invasive methods to predict and diagnose acute and chronic graft lesions, to improve patient tre...
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 13

 TERMINÉ 

QUANTItative scanning probe microscopy techniques for HEAT transfer management in nanomaterials and nanodevices (QUANTIHEAT)

Date du début: 1 déc. 2013, Date de fin: 30 nov. 2017,

The thermal properties of nanostructured materials are of fundamental importance to modern technology, but at present reproducible metrological definitions, tools and methods do not exist. This is because the mechanisms of heat transport at the nanoscale are entirely different to those at the macro scale.The project will place nanothermal metrology on a solid basis by an integrated physics-based e...
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 23

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2016, Date de fin: 30 sept. 2017,

This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
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 1

 TERMINÉ 

Predictive Position Coding (POSITION)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2017,

Vision gives us enormous adaptive advantage because it allows us to see and react to events before they reach us. This predictive advantage is most obvious for an object in motion where the current trajectory predicts future location. It is equally important when the object’s motion results from the movement of our own eyes. Here our visual system uses knowledge about the upcoming motion of the ey...
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 2

 TERMINÉ 

A tactile prosthesis to improve speech perception in persons with hearing loss. (FeelSpeech)

Date du début: 1 avr. 2016, Date de fin: 30 sept. 2017,

The “FeelSpeech” project will provide proof of concept of a novel prosthesis that will allow people with hearing loss to better understand speech. The prosthesis will be worn on the wrist and will resemble a wristwatch. A special, novel kind of tactile stimulation called “microstroking” provided by the device will supplement what a person hears, and this information will be unconsciously made use ...
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 1

 TERMINÉ 

Cystic Fibrosis Microbiome-determined Antibiotic Therapy Trial in Exacerbations: Results Stratified (CFMATTERS)

Date du début: 1 oct. 2013, Date de fin: 30 juin 2017,

Antimicrobial resistance is arguably the most significant challenge facing the EU health care system. The unnecessary use of antibiotics is a key driver in the development of antibiotic resistance. Cystic Fibrosis (CF) represents a unique disease model to study bacterial resistance and to explore therapeutic strategies for same, as chronic lung infection overlaps with acute lung exacerbations caus...
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 15

 TERMINÉ 

Open Project for the European Radiation Research Area (OPERRA)

Date du début: 1 juin 2013, Date de fin: 31 mai 2017,

"Within the OPERRA project, it is proposed that the MELODI Association, as a well-advanced network, takes the lead in establishing the necessary structures able to manage the long-term European research programmes in radiation protection, also taking advantage of the valuable experience gathered through the DoReMi network of excellence. Whilst in fields adjacent to low-dose risk research (radioeco...
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 71

 TERMINÉ 

The role of visual cues in speech segmentation and the acquisition of word order: a study of monolingual and bilingual adults and infants (VISCUESACQWO)

Date du début: 1 juin 2014, Date de fin: 31 mai 2017,

Adults and infants make use of both auditory and visual information in speech perception. The available visual cues include oral-articulatory movements (e.g., lip movements), as well as non-verbal gestures (e.g., head-movements). The present project seeks to investigate the role of visual cues as an aid for auditory prosody in speech segmentation and in bootstrapping syntactic development, topic t...
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 1

 TERMINÉ 

Imaging of Neuroinflammation in Neurodegenerative Diseases (INMiND)

Date du début: 1 mars 2012, Date de fin: 28 févr. 2017,

The goal of this proposal (INMiND) is to carry out collaborative research on molecular mechanisms that link neuroinflammation with neurodegeneration in order to identify novel biological targets for activated microglia, which may serve for both diagnostic and therapeutic purposes, and to translate this knowledge into the clinic. The general objectives of INMiND are:(i) to identify novel mechanisms...
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 32

 TERMINÉ 

"Perceptual Representation of Illumination, Shape and Material" (PRISM)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

"Visual perception provides us with a richly detailed representation of the surrounding world, enabling us to make subtle judgements of 1) 3D shape, 2) the material properties of objects, and 3) the flow of illumination within a scene. Together, these three factors determine the intensity of a surface in the image. Estimating scene properties is crucial for guiding action and making decisions like...
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 10

 TERMINÉ 

European clinical study for the application of regenerative heart valves (ESPOIR)

Date du début: 1 janv. 2012, Date de fin: 31 déc. 2016,

Acquired and congenital heart disease can necessitate heart valve replacement. However, current heart valve substitutes are not considered ideal as they need anticoagulation, bearing the risk of bleeding when manufactured from non-organic material, or they degenerate when they derive from animals or human tissue donators (homografts) thereby leading to frequent reoperation especially in the young ...
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 15

 TERMINÉ 

Synthesis of Two-Photon Optimized 'Caged' Compounds for Neuroscienes (LIGHTLAB-TOOLS)

Date du début: 1 nov. 2014, Date de fin: 31 oct. 2016,

"Progress in science requires the development of new or better experimental tools. Photolysis has provided a way to study kinetics of ligand activated signaling in situ at inaccessible intracellular and extracellular receptors for three decades. It can now be combined with laser microscopy to provide high resolution spatio-temporal kinetics of receptors in situ, for photo-stimulation or photo-inhi...
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 1

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2015, Date de fin: 30 sept. 2016,

This is a higher education student and staff mobility project, please consult the website of the organisation to obtain additional details.
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 1

 TERMINÉ 

A comprehensive approach to “attitudes towards contingency” in liberal-individualistic societies : the case of mental health problems hindering autonomy (ATCMentalHeath)

Date du début: 1 oct. 2014, Date de fin: 30 sept. 2016,

"This project deals with ""attitudes towards contingency"" - ATC - (i.e. ways of making life going on after a crisis, ways of coping with misfortune, injustice, evil, etc. on the symbolic and operative levels) that are specific to liberal- individualistic societies, within which unprecedented emphasis is put on autonomy and the capacity to rely on oneself (in particular : helping oneself, being o...
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 1

 TERMINÉ 

"The behavioral, fMRI, and EEG profiles of multifocal attention" (MUFOCA)

Date du début: 1 juil. 2013, Date de fin: 30 juin 2016,

"The proposed project will investigate how selective attention is implemented in the architecture of the visual system. Using both behavioral and cognitive neuroscience methods, we will study attentional tracking of multiple objects that move independently in the visual field. Previous research has shown that the capacity to select and monitor multiple objects and their locations varies as a funct...
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 1

 TERMINÉ 

Emotional prosody in speech: the importance of pitch, timing and loudness (EMOTION IN SPEECH)

Date du début: 1 juil. 2013, Date de fin: 25 mars 2016,

"Prosody is the ""music of speech."" Through variations in pitch, timing, loudness and voice quality it communicates grammatical, pragmatic, as well as affective information. The current project will focus on the acoustic cues that are important for the affective aspects of prosody, those which communicate emotion. By parametrically manipulating three acoustic cues, pitch, timing and loudness, in ...
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 1

 TERMINÉ 

Spatial Cognition (SpaceCog)

Date du début: 1 mars 2013, Date de fin: 29 févr. 2016,

Humanoid robots will become important machines to support mankind if they develop similar capabilities as humans have. One of those capabilities is to orient in space and to extract the relevant information from its environment. A common approach has been to build a spatiotopic map of the external world, so called an internal world model. However, since the sensors, such as the eyes (cameras) are ...
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 6

 TERMINÉ 

Governance of REsponsible innovATion (GREAT)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2016,

The GREAT project will develop an empirically based and theoretically sound model of the role of responsible research and innovation governance. The project will explore the dynamics of participation in research and innovation, and investigate the characteristics of responsible practices. It will investigate the nature of new partnerships among various stakeholders, researchers and policymakers th...
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 13

 TERMINÉ 

Frontal Asymmetry as an Endophenotypic Marker of Differential Susceptibility to Parenting in Infancy: A Functional NIRS Study (INFANT NIRS)

Date du début: 1 févr. 2015, Date de fin: 31 janv. 2016,

Infants’ social-cognitive skills develop within the parent-infant relationship. Differences between parents in the way they interact with their infant may have important consequences for infants’ social-cognitive development. Moreover, due to their genetic make-up, some individuals may be more affected by their social environment than others. Indeed, genes that may convey this differential suscept...
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 1

 TERMINÉ 

To decipher the optimal management of systemic sclerosis (DESSCIPHER)

Date du début: 1 déc. 2012, Date de fin: 30 nov. 2015,

The current approach to diagnosis and management of the rare disease systemic sclerosis (SSc) is based on American College of Rheumatology criteria with low sensitivity and few validated recommendations for the therapy of the disease and its manifold organ manifestations. To overcome these shortcomings, the DeSScipher project will use the multinational, prospective and open EUSTAR (Scleroderma Tri...
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 15

 TERMINÉ 

TRANSLATIONAL RESEARCH AND PATIENT SAFETY IN EUROPE (TRANSFoRm)

Date du début: 1 mars 2010, Date de fin: 30 nov. 2015,

TRANSFoRm will develop rigorous, generic methods for the integration of Primary Care clinical and research activities, to support patient safety and clinical research via:1.\tRich capture of clinical data, including symptoms and signs rather than just a single diagnosis. A generic, dynamic interface, integrated with electronic health records (EHR), will facilitate both diagnostic decision support ...
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 25

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2014, Date de fin: 30 sept. 2015,

Within the framework of the participation of the Paris Descartes University in the European space of higher education and research, the deployment of the Erasmus + program at the University takes a major place in the promotion of the students and staffs mobilities and above all teaching staff mobilities. The mobility office of the Paris Descartes European affairs and international relationships d...
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 1

 TERMINÉ 

Exploring Chemical Biodiversity with Innovative Approaches for Fighting Chagas and Leismaniasis (CHEMBIOFIGHT)

Date du début: 1 avr. 2011, Date de fin: 31 mars 2015,

The ChemBioFight project aims towards the exploration of natural resources to the discovery of bioactive therapeutic molecules against leishmania and Chagas disease. This will be accomplished through the establishment of an extended scientific network between European and South American research entities. Already assembled, highly diverse chemical libraries will be employed for the determination o...
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 5

 TERMINÉ 

Apoptosis Modelling for Treatment Decisions in Colorectal Cancer (APO-DECIDE)

Date du début: 1 nov. 2012, Date de fin: 31 oct. 2014,

"With the arrival of new colorectal cancer (CRC) therapeutics targeting specific cell signalling pathways, such as anti-EGFR therapy, personalised cancer treatment is at the door step of clinical practise. This progress in drug development contrasts strikingly with current clinical practice, where decision making depends largely on clinical factors such as tumour staging and age of patient, with t...
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 7