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 TERMINÉ 

Algorithmic and Mathematical Cryptology (AlmaCrypt)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Cryptology is a foundation of information security in the digital world. Today's internet is protected by a form of cryptography based on complexity theoretic hardness assumptions. Ideally, they should be strong to ensure security and versatile to offer a wide range of functionalities and allow efficient implementations. However, these assumptions are largely untested and internet security could...
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 3

 TERMINÉ 
Many HIV vaccine concepts and several efficacy trials have been conducted in the prophylactic and therapeutic fields with limited success. There is an urgent need to develop better vaccines and tools predictive of immunogenicity and of correlates of protection at early stage of vaccine development to mitigate the risks of failure. To address these complex and challenging scientific issues, the Eur...
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 43

 TERMINÉ 

European AIDS Vaccine Initiative 2020 (EAVI2020)

Date du début: 1 nov. 2015, Date de fin: 31 oct. 2020,

HIV-1 is responsible for a global pandemic of 35 million people, and continues to spread at a rate of >2 million new infections/year. It is widely acknowledged that a protective vaccine would be the most effective means to reduce HIV-1 spread and ultimately eliminate the pandemic, while a therapeutic vaccine may help mitigate the clinical course of disease and lead to strategies of viral eradicati...
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 27

 TERMINÉ 

Wave turbulence: beyond weak turbulence (WATU)

Date du début: 1 oct. 2015, Date de fin: 30 sept. 2020,

Wave turbulence and fluid turbulence belong to the same class of turbulent states made of a large number of nonlinearly coupled degrees of freedom driven far from equilibrium. The Weak Turbulence Theory is a statistical theory of low amplitude turbulent waves. The predicted phenomenology (energy cascade) is very similar to that of fluid turbulence, which badly lacks such a statistical theory. Weak...
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 2

 TERMINÉ 

Algebraic and Kähler geometry (ALKAGE)

Date du début: 1 sept. 2015, Date de fin: 31 août 2020,

The purpose of this project is to study basic questions in algebraic and Kähler geometry. It is well known that the structure of projective or Kähler manifolds is governed by positivity or negativity properties of the curvature tensor. However, many fundamental problems are still wide open. Since the mid 1980's, I have developed a large number of key concepts and results that have led to important...
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 2

 TERMINÉ 
Despite significant progress in cancer therapy, current treatments are still controversial due to intolerable side effects. Targeted immunotherapy has recently emerged as an ideal alternative to improve treatment modalities for cancers patients. However, very limited approaches are available today and major issues remain to be addressed. The ERC grant offers a unique opportunity to propose a new p...
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 2

 TERMINÉ 

Combatting Bacterial Resistance in Europe (COMBACTE-NET)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2019,

The emergence of Antibiotic-resistant bacteria (ARB) is a global problem, having recently been elevated to the top three threats identified by the World Health Organisation (WHO), and subject of numerous national and international government activities, including the Trans-Atlantic Task Force on Antimicrobial Resistance established by the US and EU presidencies. The estimated costs of ARB are aro...
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 38

 TERMINÉ 
We propose to use a combination of data from the ESA space missions GAIA and Herschel, alongside other satellite and European-led ground-based observations, to map the density distribution of star formation regions. This will allow us to identify the mechanisms that underlie both how massive stars themselves form, but more fundamentally, how their natal clusters evolve around them. Our work wi...
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 5

 TERMINÉ 
The continuous increase of the share of renewable energy sources is redefining the electrical networks. In future infrastructures, an important number of agents (sources, storage devices and consumers) will have intelligent interfaces allowing the regulation of the injection and extraction of power into the grid. This context will create multiple alternatives to increase the efficiency in electric...
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 9

 TERMINÉ 
OpenDreamKit will deliver a flexible toolkit enabling research groups to set up Virtual Research Environments, customised to meet the varied needs of research projects in pure mathematics and applications and supporting the full research life-cycle from exploration, through proof and publication, to archival and sharing of data and code.OpenDreamKit will be built out of a sustainable ecosystem of ...
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 17

 TERMINÉ 
The key therapeutic issue in diabetes mellitus type I and II is glycaemic control. Reductions of constant self-control, of insulin injections, and of long-term complications would have tremendous benefit for quality of life. The best therapy option is the transplantation of allogeneic islet cells, but the current state of the art limits the applicability of this approach. Implanting unprotected gr...
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 10

 TERMINÉ 
BISON will enhance the collaborative framework of the Central European Institute of Technology of Masaryk University (CEITEC MU), which was created during 2011-14 by utilising synergies of Structural Funds and the Framework Programme, with its three internationally-leading counterparts in the fields of structural biology by extending expertise related trans-disciplinary areas. The goal is to stimu...
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 5

 TERMINÉ 
IMMUNOSHAPE aims at training a new generation of scientists that will be capable of combining state of the art synthesis and screening technology to develop new lead structures for highly selective glycan based multivalent immunotherapeutics for the treatment of cancer, autoimmune diseases and allergy. To this end, we have set up a training program in a unique academic-industrial environment that ...
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 17

 TERMINÉ 

Unifying Control and Verification of Cyber-Physical Systems (UnCoVerCPS)

Date du début: 1 janv. 2015, Date de fin: 31 déc. 2018,

The proposed research effort provides methods for a faster and more efficient development process of safety- or operation-critical cyber-physical systems in (partially) unknown environments. Cyber-physical systems are very hard to control and verify because of the mix of discrete dynamics (originating from computing elements) and continuous dynamics (originating from physical elements). We present...
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 11

 TERMINÉ 

Frequency-to-current conversion with coherent Josephson crystals (FREQUJOC)

Date du début: 1 janv. 2013, Date de fin: 30 avr. 2018,

This project aims at exploring the coherence of Josephson crystals (JC) and to apply this coherence for frequency-to-current conversion. A Josephson crystal can be realized by a Josephson junction chain, formed by repeating a single junction or SQUID in space to form a one-dimensional ladder structure. Such a crystal can show a macroscopic coherent behavior due to the coherent superposition of qua...
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 2

 TERMINÉ 

Challenges in Extraction and Separation of Sources (CHESS)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2018,

Separation/extraction of sources are wide concepts in information sciences, since sensors provide information mixing and an essential step consists in separating or extracting useful information from unuseful one, called noise. In this project, we consider three challenges.The first one is the multimodality. Indeed, with the multiplication of kinds of sensors, in many areas like biomedical signal ...
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 2

 TERMINÉ 

Critical State Soil Mechanics Revisited: Fabric Effects (SOMEF)

Date du début: 1 mars 2012, Date de fin: 28 févr. 2018,

The theory of Critical State Soil Mechanics (CSSM) has become a paradigm within the framework of which elastoplastic soil constitutive models have been developed for the last 50 years. The present project will constructively challenge this paradigm from a missing fundamental perspective, namely the effect of soil fabric on the premises of CSSM.The current CSSM postulates that at critical state the...
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 4

 TERMINÉ 

Mineral Intelligence Capacity Analysis (MICA)

Date du début: 1 déc. 2015, Date de fin: 31 janv. 2018,

Primary and secondary raw materials are fundamental to Europe’s economy and growth. They represent the most important link in the value chain of industrial goods production, which plays a prominent role as a source of prosperity in Europe. However, as stated in the call, there exists to-date no raw materials knowledge infrastructure at EU level. The Mineral Intelligence Capacity Analysis (MICA) p...
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 17

 TERMINÉ 

Geometry and Topology of Open Manifolds (GETOM)

Date du début: 1 févr. 2013, Date de fin: 31 janv. 2018,

The purpose of this project is to study the interactions between Riemannian Geometry and the topology of open manifolds. A general question is to find the best Riemannian metric on a given manifold; a related question is to understand the topological consequences of the existence of a metric with given properties. This programme has already been highly successful in the compact case whereas basic ...
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 2

 TERMINÉ 

STATic analysis with ORiginal methods (STATOR)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2017,

Since the beginning of computing, software has had bugs. If a word processor crashes, consequences are limited. If a networked application has security bugs (e.g. buffer overflows), important information (e.g. financial or medical) can leak. More importantly, today's planes are flown by computers, voting machines as well medical devices such as infusion pumps are computerized, and surgeries are pe...
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 2

 TERMINÉ 

Investigating Tectonism-Erosion-Climate-Couplings (ITECC)

Date du début: 1 janv. 2013, Date de fin: 30 juin 2017,

Tectonics and climate are interdependent. The tectonics of orogens are moderated by climate through erosion. Exposure of rock by tectonics or erosion is critical to the feedback which governs changes in global climate, whilst topography influences rainfall. The principle objective of iTECC is to use the Himalaya as a natural laboratory to train young scientists in understanding such coupled proces...
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 11

 TERMINÉ 

Driven Glasses: from statistical physics to materials properties (GLASSDEF)

Date du début: 1 juil. 2012, Date de fin: 30 juin 2017,

Amorphous systems form a large fraction of the solid materials that surround us, from polymer glasses to mineral or metallic glasses, from toothpaste (a colloidal paste) to granular materials. Still, a theoretical framework for describing the mechanical properties of such materials, comparable to the dislocation theory that describes crystalline systems, is still missing. Our understanding of prom...
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 2

 TERMINÉ 

Arrowhead (ARROWHEAD)

Date du début: 1 mars 2013, Date de fin: 28 févr. 2017,

"Our society is facing both energy and competitiveness challenges. These challenges are tightly linked and require new dynamic interactions between energy producers and energy consumers, between machines, between systems, between people and systems, etc. Cooperative automation is the key for these dynamic interactions and is enabled by the technology developed around the Internet of Things and Ser...
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 87

 TERMINÉ 

Scalable ProactivE Event-Driven Decision making (SPEEDD)

Date du début: 1 févr. 2014, Date de fin: 31 janv. 2017,

SPEEDD (Scalable ProactivE Event-Driven Decision making) will develop a system for proactive event-based decision-making: decisions will be triggered by forecasting events -whether they correspond to problems or opportunities- instead of reacting to them once they happen. The decisions and actions will be real-time, in the sense that they will be taken under tight time constraints, and require on-...
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 10

 TERMINÉ 

Assess Inquiry in Science, Technology and Mathematics Education (ASSIST-ME)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

ASSIST-ME is a high level research project with a societal impact that will investigate formative and summative assessment methods to support and to improve inquiry-based approaches in European science, technology and mathematics (STM) education. Based on an analysis of what is known about summative and formative assessment of knowledge, skills and attitudes related to key STM competences and an a...
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 11

 TERMINÉ 
NEURINOX aims at elucidating the role of NADPH oxidases (NOX) in neuroinflammation and its progression to neurodegenerative diseases (ND), as well as evaluating the potential of novel ND therapeutics approaches targeting NOX activity. NOX generate reactive oxygen species (ROS) and have emerged as regulators of neuroinflammation. Their role is complex: ROS generated by NOX lead to tissue damage in ...
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 15

 TERMINÉ 

Flow in Transforming Porous Media (FlowTrans)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2016,

The FlowTrans Initial Training Network is a unique environment for career development, built on joint challenges of Industry and University partners in a newly emerging supra-disciplinary field, spanning from Physics to Earth Sciences and aiming to understand Flow in Transforming Porous Media. Training will be hosted by 8 Universities in synergy with 2 full and 4 associated industry partners with ...
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 10

 TERMINÉ 

Compound Semiconductors for 3D integration (COMPOSE3)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,

COMPOSE3 aims to develop 3D stacked circuits in the front end of line of Complementary Metal Oxide Semiconductor (CMOS) technology, based on high mobility channel materials. The final objective is a 3D stacked SRAM cell, designed with gates length taken from the 14nm technology node. This technology will provide a new paradigm shift in density scaling combined with a dramatic increase in the power...
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 10

 TERMINÉ 

Evolution of Evolution (EvoEvo)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2016,

Evolution is the major source of complexity on Earth, at the origin of all the species we can observe, interact with or breed. On a smaller scale, evolution is at the heart of the adaptation process for many species, in particular micro-organisms (e.g. bacteria, viruses...). Microbial evolution results in the emergence of the species itself, and it also contributes to the organisms' adaptation to ...
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 7

 TERMINÉ 

The Human Brain Project (HBP)

Date du début: 1 oct. 2013, Date de fin: 30 sept. 2016,

Understanding the human brain is one of the greatest challenges facing 21st century science. If we can rise to the challenge, we can gain profound insights into what makes us human, develop new treatments for brain diseases and build revolutionary new computing technologies. Today, for the first time, modern ICT has brought these goals within sight. The goal of the Human Brain Project, part of the...
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 116

 TERMINÉ 
The Mont-Blanc project aims to develop a European Exascale approach leveraging on commodity power-efficient embedded technologies. The project has developed a HPC system software stack on ARM, and will deploy the first integrated ARM-based HPC prototype by 2014, and is also working on a set of 11 scientific applications to be ported and tuned to the prototype system.The rapid progress of Mont-Blan...
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 17

 TERMINÉ 
Description The objective of this research proposal is to bring time awareness and evolution into the design of System-of-Systems (SoS), to establish a sound conceptual model, a generic architectural framework and a design methodology including tools for prototyping, for the modeling, development and evolution of time-sensitive SoSes with po...
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 7

 TERMINÉ 
Critical Infrastructures (CIs) provide essential goods and services for modern society; they are highly integrated and have growing mutual dependencies. Recent natural events have shown that cascading failures of CIs have the potential for multi-infrastructure collapse and widespread societal and economic consequences.Moving toward a safer and more resilient society requires improved and standardi...
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 13

 TERMINÉ 

Transatlantic CPS Summit (CPS Summit)

Date du début: 1 févr. 2015, Date de fin: 31 juil. 2016,

Cyber-physical systems (CPS) are a core enabling technology for securing economic leadership in embedded systems and ICT, having an enormous social and economic importance, and making decisive contributions to societal challenges. The EU and the US face common challenges to push forward the limits of the science for engineering CPS, creating a favorable environment for strategic and pre-competitiv...
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 6

 TERMINÉ 

Higher education student and staff mobility project

Date du début: 1 juin 2014, Date de fin: 31 mai 2016,

The International policy of Université Joseph Fourier is built around three principles: the attractiveness of the university, its international partnerships and mobility for all. Being an active part of the Erasmus+ program and particularly in Key Action 1 for Higher Education is at the heart of our international strategy. The main aim of the project was to promote the new Erasmus+ program within ...
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 1

 TERMINÉ 
"The principal strategic objective of INTERCROSSING is the cultivation of a new type of young researcher to deal with challenges of exploiting the latest Next Generation Sequencing (NGS) technologies – individuals with rigorous training in three disciplines hardly ever found together any one young scientist: population genetics, informatics and statistics. The need for this supra-disciplinary com...
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 10

 TERMINÉ 
"The search for planets outside of the solar system, related to the question ""are we alone in the universe?"", is undoubtedly one of the main science drivers for the current design of telescopes and astronomical instrumentation. In this FP7 project, we will study the birth-places of such exo-planets, the so-called protoplanetary discs, by combining multi-wavelength space data (HERSCHEL, XMM, HST,...
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 6

 TERMINÉ 
European IC manufacturers are on the way to become suppliers of customized products for OEM companies, which means high flexibility and product diversity. The project aims at conducting research to support the development of new manufacturing procedures, new organizations and new information and control tools to enable IC production lines to efficiently manage a high product and technology mix and...
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 29

 TERMINÉ 

Information, Fluctuations, and Energy Control in Small Systems (INFERNOS)

Date du début: 1 janv. 2013, Date de fin: 31 déc. 2015,

Strong statistical fluctuations in meso- and nano-scale structures make their thermodynamic properties extremely dependent on the information available about them. The most basic process illustrating the importance of information to statistical systems is the information-to-energy conversion in the famous Maxwell's Demon (MD). Our primary goal is to study both experimentally and theoretically the ...
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 9

 TERMINÉ 
Permafrost is defined as ground that remains continuously at or below 0°C for at least two consecutive years; some 24% of the land surface in the northern Hemisphere is classified as permafrost. In the Northern high latitudes, strong warming has been observed over the recent decades, and climate models project strong future warming. A projected decline in the extent of permafrost will have a major...
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 20