Fraunhofer ITEM


: 2 mai 2016


Recherche partenariat
A propos

In Vitro Toxicology, different biological test systems (primary cell cultures of human and animal origin, immortal and transgenic cell lines, co-culture systems, precision-cut liver and lung slices), different in vitro exposure conditions (liquid or soluble test substances, particulate substances in suspensions, airborne test substances as gases, aerosols, and particles) in the patented culturing and exposure system PRIT-ALI. In vitro ADME, CYP450 Characterization, OECD Guideline studies, GLP certification

Genotoxicity: Comet-assays, Micronucleus-assays, Chromosomal abberation assay

Functional Assays: Cytotoxicity, Oxidative Stress, Apoptosis/Senescence, Inflammation, DNA-damage/repair, Cell Cycle Analysis, Particle uptake, Transport studies

Analysis of molecular mechanism of action: Gene expression analysis, Toxicity signature and pathway-specific analysis (real-time RTqPCR based arrays), Transcriptom-wide gene expression analysis (Affymetrix-Microarrays), Epigenetics

Mots clés et domaine d'activité:

 Environnement
 Soins de santé
 Cosmétiques
 Médicaments
 Produits chimiques
 Nanotechnologie et nanosciences
 Horizon Europe

Idées proposées

Appels à projets suivis
Pas d'appels à projets suivis!