The municipal economy of the towns of Zeliezovce and Isaszeg is created by Small and Medium Enterprises. This enterprises are negatively influenced by global crises, insufficient development of business and transport infrastructure, insufficient development of region, low minicipality demand and low level of cross-border business partnership All this factors has caused low level of economy development of municipality business entities. Our research results has showed, that enterprises want to be supported by municipality and want to build cross-border business partnership as well. All this needs will be covered by new Zeliezovce Isaszeg Business Centre. Achievements: Želiezovce and Isaszeg can be found in a region with high rate of unemployment. The cities lack big and strong companies, besides public services, the only employers are the small and medium size enterprises. According to local surveys, entrepreneurs considered support from the municipalities insufficient in both towns. The entrepreneur partners decided to create special services for small size enterprises and start-ups. As a first step, partners reconstructed two business centres in Želiezovce and Isaszeg. After the reconstruction, the partners opened an advisory office for the entrepreneurs providing several types of consultancy services in the field of law, taxation, economy and entrepreneurship.