United4Health aims to exploit and further deploy innovative telemedicine services implemented and trialled under the RENEWING HEALTH project. A limited number of interventions have been selected from the basket of those already validated or under validation in RENEWING HEALTH; they will be trialled in 14 regions to guarantee aggregation of data and comparability of results. All service solutions adopt a patient centred approach, and involve the telemonitoring and the treatment of chronic patients with diabetes, COPD or CVD diseases. Services are designed to give patients a central role in the management of their diseases, fine-tuning the choice and dosage of medications, promoting compliance to treatment, and helping professionals to detect early signs of worsening. The services to be implemented are: Life-long management of diabetes, Short-term follow-up after hospital discharge for COPD patients, Remote monitoring of Congestive Heart Failure. The Project will operate as a multi-centre clinical trial measuring efficiency and the cost effectiveness of the implemented solutions. This will give scientific validity to the results and will promote adoption of remote patient monitoring and treatment on a large scale. The effectiveness of the solutions will be evaluated using the MAST methodology. MAST, developed by two of the partners, is increasingly the method of choice for evaluating healthcare projects. United4Health pilots will progressively convergence towards common interoperable architectures. The Project is supported by national Health Authorities of the participating regions which have responsibility for the healthcare budget; they are fully committed to deploy the telemedicine services in their territory and also to co-operate among themselves to promote the further uptake of the services at pan-European level. Thanks to its leveraging power United4Health has mobilised 9,0 M€ of additional funding to top up ICT PSP contribution and contractual co-funding.