"The OPENGENE proposal of Estonian Genome Project, Tartu University arises directly from the institutional SWOT analysis and responds precisely to the objectives of the current call. The general objective of the proposal is opening the EGPUT research potential and biobank resources to ERA. To this end we have designed a set of coherent measures that in an interconnected manner contribute to the R&D capacity and capability building of the EGPUT and by means of significant upgrading of the research infrastructure attract collaboration partners from other EU countries to achieve better utilization of the EGPUT biobank. We present a work plan that is structured coherently according to the five general measures of the call. The plan foresees recruitment of experienced researchers from the EU and beyond to launch two new research groups in the EGPUT covering fields of modern biomedicine that are underrepresented in Estonia. In this activity repatriating Estonian nationals are encouraged to apply. We further develop exchange of know-how and experience by building new and reinforcing established tight cooperation relations with leading European Research institutions. We plan to organize hands-on training courses / seminars in modern genetics and genEthics. We plan to invest significantly into increasing our visibility both in European R&D community and local general public, using the most appropriate channels of communication in both cases. A transparent public discussion concerning bio-ethics rising public awareness in genetic and biomedicine research are integral to the public dissemination. As a specific measure undertaken to significantly increase the accessibility an quality of the EGPUT biobank infrastructure we plan to build a high-throughput genotyping and sequencing platform by acquisition of iScan system by Illumina."