Computer simulations are an increasingly popular tool for investigating and enhancing our knowledge of the human body. They can provide valuable insights and provide in silico experiments to test hypotheses of complex biological relationships. Due to the inherent complexity of the structures and the highly-specialised area of expertise of the researcher/user, computational models are often reduced to the components that are essential to fulfil the least amount of assumptions such that their results can be interpreted and discussed within a specific context. The purpose of this proposal is to bring together researchers with complementary expertise to develop (i) detailed models of complex musculoskeletal systems (the ‘next generation models’) and (ii) a novel web interface to disseminate those models. The improvement of models existing in research groups participating in this proposal will include the spine, hip, pelvic floor, and the tongue. A special focus will be on the inclusion of 3D soft tissue structures, e.g. skeletal muscles, and their material descriptions. The aim of the interface is to provide easy access to such near-complete descriptions of complex models. The interface is guided by the development of the models and will appeal to similar concepts as standard web pages and the ability to include 3D scenes of models. This can only be achieved through an international network of well-established research groups with expertise in material science, computational science, software design, whole organ modelling, modelling biotribological systems, clinical contacts, biomechanics, sports science, etc. The network includes the Cluster of Excellence for Simulation Technology, SimTech (University of Stuttgart, Germany), the Institute of Medical and Biological Engineering (University of Leeds, UK), the Auckland Bioengineering Institute (University of Auckland, New Zealand), and the Medical Engineering Research Theme (Queensland University of Technology, Australia).