IRB Barcelona is an independent, non-profit research institution engaged in basic and applied biomedical science at the interface between biology, chemistry and medicine, recently nominated a Severo Ochoa Centre of Excellence by the Spanish Ministry of Science and Innovation. One of the main missions of IRB Barcelona is to provide young life scientists with the opportunity to do training and research in a unique and multidisciplinary scientific environment.We are applying for contribution from the COFUND action to give continuity to the fellowship programme for postdoctoral fellows that initiated last year thanks to the contribution of a previous COFUND call: after having consolidated our PhD Programme and achieved excellent results, our aim is now to draw on the strength of this example and enhance structures and resources for researchers at the next stage of their careers. We offer postdoctoral fellows an optimal scientific environment to prepare them on their journey to take up positions as independent scientists. The IRB Barcelona International Postdoctoral Programme will offer 16 two-year competitive fellowships, based on the Incoming mobility trans-national element. Fellows will be selected through an international committee of experts, ensuring transparency and equal treatment of all applications. The programme will be promoted internationally. Applicants will receive support throughout the selection process and awardees will be helped and mentored for the duration of the fellowship period. Postdoctoral fellows under the COFUND contribution can carry out their research projects in any of IRB Barcelona’s research programme. The programme will make significant contributions to the development of highly talented scientist’s career and to the biomedical sciences in general.