Ion ChaNnel SENSors
Date du début: 1 avr. 2014,
Date de fin: 31 mars 2015
Super-sensitive detection mechanisms offer numerous opportunities for fundamental science in fields such as biophysics and chemistry and are a highly needed advancement for applied fields such as medicine, environmental pollution monitoring and defence. Developing sensors that are even capable of detecting single molecules has therefore become an important field of research. At this moment there is a growing demand for a stable and sensitive molecular sensing method because the available sensing methods are insufficient.Dr. Kocer and her group have developed a sensory device based on biological ion channels. Ion channels are extremely sensitive transmembrane protein pores that open and close in response to chemical, electrical or mechanical stimuli. Dr. Kocer has built unique knowledge and expertise on the channel functioning that allows her to modify the sensory characteristics of these channels towards the detection of a certain analyte. Via a unique fabrication method a sensory chip has been constructed where ion channels can be reconstituted into an artificial bilayer lipid membrane. This has led to the development of a molecular sensing platform able to detect a large variety of analytes at the single molecule level.To maximise the full potential of the ion channels, we will explore in which fields a molecular platform can fulfil major unmet needs and develop a reliable molecular sensing platform. To achieve these goals, we will conduct market research, develop a sound commercialisation strategy, IPR strategy and a product development plan within the ERC PoC project. The project outcomes will be consolidated in a business plan and presented to investors including venture capitalists and other strategic partners.
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