Regional competitiveness and growth often depend on the ability of regional institutions to stimulate entrepreneurial culture in their regions to build social capital and to reinforce the internationalization of small businesses. However, many regions, particularly those lagging behind, lack pro-active policies to address these needs. Based on the experiences of a successful Polish-Swedish cooperation focusing on entrepreneurship and regional development, the operation "E-Teams - Interregional Entrepreneurial Teams" aims to improve the knowledge-base of its partnership and offer an interregional platform to work on joint solutions. Overall objective / Objectif général E-Teams aims to: (1) increase knowledge amongst local and regional policy-makers and other stakeholders on how to assist SMEs in their development and internationalization processes, (2) build capacity among relevant actors in the regions to identify and meet the needs of SMEs, (3) stimulate interaction between SMEs, universities and local and regional policy-makers, (4) design and test approaches facilitating access for SMEs to knowledge, and (5) provide input for reforming regional development policies and practices. Expected results / Résultats attendus E-Teams results in increased knowledge on efficient SMEs policies and practices in eight regions and improved intervention skills of public actors. Furthermore, it increases comparability of regional performance data through the establishment of a joint benchmark and indicator system. Activities include the establishment of Multi-Actor Partnerships (MAP) to secure broad involvement and support for pro-active policies in the partner regions. MAPs consists of wider regional partnerships, including local and regional policy makers, universities, and business support organizations. Partners also establish Entrepreneurial Teams (E-teams) that include SMEs of different sectors to test ideas for SME support in a real business environment and to help design new policy approaches and regional action plans on SME support. The lessons learned are in a handbook and in policy-papers.