The sustainable development applications were of utmost interest. But most of the countries recently entered the European Union lack of competences and skills to develop innovative companies in the domain. The situation in Romania was compared with other EU countries, members of the European Federation of Biotechnology. In the BELA project were developed learning curricula and contents which were delivered to target-group by blended learning in order to provide training in business enhancement in life sciences for sustainable development applications. The target group comprises young entrepreneurs promoting sustainable development applications, scientists preparing to pass from the research field to the business sector and educators involved in teaching entrepreneurship. The products and results were ready to implement in the partnerships countries, but also in other European areas. The consortium consists of 4 partners from Romania (ICECHIM and USAMV Bucharest), France (AFMR Etcharry) and Lithuania (Kaunas STP) with complementary expertise and competences especially chosen to fulfill the project work program, meaning the two Romanian partners participated with specialists in life sciences research, high education and training, the French partner had experience in delivering training for organizing partnerships and networks for rural sustainable development, and the Lithuanian partner developed training to promoted the growth of entrepreneurial spirit. Two products from these foreign partners were transferred, by integrating them, but also by adapting to an economic sector of interest and by introducing modern blended learning systems, and by increasing the value with a new specific content dedicated to sustainable life sciences applications. The enterprise business in life sciences module were complementary treat the Intellectual Property issues. The impact was identified on 3 levels: (1) short term: acknowledge the key competences and skills needed to developed business in sustainable development applications of life sciences and developed blended learning by testing the training on a representative target group; (2) medium term: formation in the involved countries and at EU level of a general vision about the training in the field of interest as products and methodologies; (3) long term: at EU level introduction into educational and vocational systems of advanced and coherent learning tools to enhance the needed competences.