BCIs with Rapid Automated Interfaces for Nonexperts (BRAIN) will develop BCIs into practical assistive and ICT tools to enhance inclusion for a range of different disabled users. Many of these people would otherwise have little or no opportunity to interact with loved ones, carers, home appliances and assistive devices, or personal computer and internet technologies. BRAIN will improve BCI reliability, flexibility, usability, and accessibility while minimizing dependence on outside help. These improvements will entail upgrades to all four components of a BCI system - signal acquisition, operating protocol, signal translation, and application. Lightweight, inexpensive, non-invasive sensors and amplifiers for signal acquisition will be developed that do not require significant preparation or cleanup times, uncomfortable electrode gel, skin abrasion, exposed wires or cables, expert assistance, or laboratory conditions. Software will identify the best BCI parameters for each user and customize the operating protocol accordingly. Automated signal processing software will improve signal translation. An intuitive universal interface will enable control of a range of existing applications, including home assistive technologies, a BCI training system to enhance performance, and a communications and entertainment package. By incorporating existing, well established tools, combined with the strengths of this multi-disciplinary consortium, these goals are now attainable. Knowledge will be disseminated through conferences, workshops, and academic papers. A website with open source software and support tools will promote standardization and both commercial and academic development within and beyond the consortium. It is envisaged that such scientific and technical advances will advance wide scale deployment of BCI, establishing it as an assistive technology of choice for existing and new user groups