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Plus de 40 projets européens trouvés

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 EN COURS 

Optimizing a deployable high efficacy malaria vaccine (OptiMalVax)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2021,

A highly effective malaria vaccine against Plasmodium falciparum should help prevent half a million deaths from malaria each year. New vaccine technologies and antigen discovery approaches now make accelerated design and development of a highly effective multi-antigen multi-stage subunit vaccine feasible. Leading malariologists, vaccine researchers and product developers will here collaborate in ...
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 17

 EN COURS 
The Persian Empire (539-330 BCE) represented a new political order in world history. At its height, it united a territory stretching from present-day India to Libya. It was three times as large and twice as long-lived as the previously most successful polity (Assyria), and it would take 2,000 years before significantly larger empires emerged in early modern Eurasia. What explains Persia’s success? ...
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 1

 EN COURS 
The vision of EU-ToxRisk is to drive a paradigm shift in toxicology towards an animal-free, mechanism-based integrated approach to chemical safety assessment. The project will unite all relevant disciplines and stakeholders to establish: i) pragmatic, solid read-across procedures incorporating mechanistic and toxicokinetic knowledge; and ii) ab initio hazard and risk assessment strategies of chemi ...
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 43

 EN COURS 
What made the early Islamic empire so successful and have we missed the story by neglecting crucial evidence? The 7th-century Arab conquests changed the socio-political configurations in the Mediterranean and Eurasia forever. Yet we do not really know how the Arabs managed to gain dominance of this vast, ethnically, religiously and linguistically diverse area which had its own, long imperial tradi ...
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 1

 EN COURS 
Human behavior is commonly understood as emerging from a struggle between will and habit, i.e., between “intentional” processes driven by the current goal and “automatic” processes driven by available stimuli. This scenario suggests that it is mainly the goal-related processes that render behavior adaptive. Based on a novel theoretical framework (the Metacontrol State Model, combined with the Theo ...
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 1

 EN COURS 

The neural basis of prosocial development in adolescence (PROSOCIAL)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,

Adolescence is an important transition period in life, where individuals gain independence from their caregivers and develop into adults who pursue their own goals. Our understanding of this transition period has benefited from two decades of research on brain development, in which it was discovered that adolescence represents a period of risk for heightened emotional reactivity, and that the deve ...
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 1

 EN COURS 

From Fermi to Planck : a bottom up approach (NuBSM)

Date du début: 1 oct. 2016, Date de fin: 30 sept. 2021,

The Standard Model of particle physics is a hugely successful theory that has been tested in experiments at ever increasing energies, culminating in the recent discovery of the Higgs boson. Nevertheless, some major riddles cannot be addressed by the Standard Model, such as neutrino oscillations, the existence of Dark Matter, the absence of antimatter in the Universe. New fundamental principles, in ...
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 3

 EN COURS 
This is a proposal to use a new ground-breaking spectroscopic technique to study the atmospheres of extrasolar planets. Understanding planet atmospheric processes and their evolutionary histories is crucial for unambiguously identifying biomarker gases, and forms the main driver behind the enormous surge in exoplanet atmospheric research. I propose to lead a program using the new VLT CRIRES+ instr ...
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 1

 EN COURS 
This is a study of the morality of commercial life insurance. What moral issues are raised when commercial companies define responsibilities for misfortune and the appropriateness of entitlements? What are the concerns about the financialization of life and intimacy?First, this study examines the morality of bureaucratic classifications produced by the insurance industry. Classifications reveal pa ...
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 1

 EN COURS 
The 39-m European Extremely Large Telescope (E-ELT) has the potential to directly observe and characterize habitable exoplanets, but current technologies are unable to sufficiently suppress the starlight very close to the star. I propose to develop a novel instrumental approach with breakthrough contrast performance by combining coronagraphs based on brand-new liquid crystal technology, and sensit ...
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 1

 EN COURS 

Optical Infrared Coordination Network for Astronomy (OPTICON)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2020,

Europe has become a global leader in optical-near infrared astronomy through excellence in space and ground-based experimental and theoretical research. While the major infrastructures are delivered through major national and multi-national agencies (ESO, ESA) their continuing scientific competitiveness requires a strong community of scientists and technologists distributed across Europe’s nations ...
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 34

 EN COURS 
Two-dimensional materials (2DMs) such as graphene, hexagonal boron nitride, silicene and others, are currently amongst the most intensively studied classes of materials that hold great promise for future applications in many technological areas. However, the main hurdle against practical utilization of 2DMs is the lack of effective mass production techniques to satisfy the growing qualitative and ...
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 7

 EN COURS 
This proposal sprang from European scientists in both academia and industry who identified a common challenge: setting up a training frame to educate the next generation of imagers in complex biological systems (healthy & pathological), so they are able to master all major aspects of this competitive field and bring important innovations to universities and companies.The long-term goal of any init ...
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 11

 EN COURS 
A novel concept for a photo-electro-catalytic (PEC) cell able to directly convert water and CO2 into fuels and chemicals (CO2 reduction) and oxygen (water oxidation) using exclusively solar energy will be designed, built, validated, and optimized. The cell will be constructed from cheap multifunction photo-electrodes able to transform sun irradiation into an electrochemical potential difference (e ...
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 15

 EN COURS 

New therapies for uveal melanoma (UM Cure 2020)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2020,

Uveal melanoma (UM) is a rare intraocular tumour with an incidence of 5 cases per million individuals per year. Up to 50% of UM patients develop metastases, most often in the liver, and these are invariably fatal. Despite new discoveries in the genetic and molecular background of the primary tumour, little is known about the metastatic disease; furthermore, there is no therapy to either prevent or ...
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 13

 EN COURS 
Fathers have largely been neglected in parenting research -- although they constitute about 50% of parents. The aim of the proposed project is to test the hypothesis that fathers’ parenting is under hormonal control and can be changed by behavioral and hormonal interventions. I propose a series of randomized controlled trials (RCT) focusing on a critical phase of parenthood: the transition to havi ...
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 1

 EN COURS 

Common mechanisms and pathways in Stroke and Alzheimer's disease. (CoSTREAM)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2020,

Common mechanisms and pathways in Stroke and Alzheimer's disease.It has long been recognized that stroke and (Alzheimer’s Disease) AD often co-occur and have an overlapping pathogenesis. As such, these two diseases are not considered fellow travelers, but rather partners in crime. This multidisciplinary consortium includes epidemiologists, geneticists, radiologists, neurologists with a longstandin ...
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 11

 EN COURS 
Large Polycyclic Aromatic Hydrocarbon (PAH) molecules are deeply interwoven in the fabric of the Universe and lock up ~15% of the elemental carbon in the interstellar medium (ISM) of galaxies. They dominate the mid-infrared emission characteristics of galaxies that can be used to trace star formation locally as well as in the early universe, they influence the phase structure of the ISM and the st ...
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 9

 EN COURS 
Around 461 million ton/year of C&DW are generated in EU28. Recent studies on the characterization of C&DW samples at European level revealed a predominant fraction of concrete (52% average). Over the last years, novel technology has been developed aiming to guarantee high quality recycled concrete aggregates for use in new concrete, thereby closing the concrete loop. The most advanced concrete re ...
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 15

 EN COURS 
Approximately 10% of the world’s population is estimated to be disabled and this number is expected to rise in the next few decades. People in different cultural settings ascribe different meanings to disability; consequently, its repercussions are both culturally contingent and universal. This project brings together the local and global dimensions of disability and examines the interaction, tens ...
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 1

 EN COURS 

Circular European Economy Innovative Training Network (CircEuit)

Date du début: 1 sept. 2016, Date de fin: 31 août 2020,

Circ€uit – the Circular European Economy Innovative Training Network - creates a cohort of future leaders in research, policy & business through its innovative training programme focused on the Circular Economy. Circular business models, based on leasing or providing functionality rather than products, often called Product Services Systems, are widely seen as a way how business can create sustaina ...
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 7

 EN COURS 

Beta Cell Generation by Stem Cell-Derived Implants in Diabetes (BetaCellTherapy)

Date du début: 1 déc. 2015, Date de fin: 31 août 2020,

Despite improved treatment, diabetes remains a chronic disease with major health risks and heavy burden on patients and society. Serious forms are caused by depletion in pancreatic beta cells and associated loss in insulin’s homeostatic control throughout life. Their cure requires restoration of a metabolically adequate beta cell mass. Implants of beta cell grafts prepared from human pancreases ha ...
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 8

 EN COURS 
Transparency in politics is the mantra of democratic governance. Should state secrecy, such as classified intelligence programs or closed-door political bargaining be abolished? Despite its revered status, many feel that complete transparency would undermine effective functioning of governments. Take the public responses to the Wikileaks disclosures: many of the disclosures were assessed favorably ...
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 1

 TERMINÉ 
Greek Mycenaean monumental architecture has been well-studied. However, the extent to which large-scale building programmes contributed to the socioeconomic and political changes and crises that took place in Late Bronze Age Greece (c.1600-1100/1070 BC) has not been studied. The project aims to investigate human and natural resources which interacted in the Argive Plain and Attica. There, elites m ...
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 1

 TERMINÉ 

Biomimetic Copper Complexes for Energy Conversion Reactions (Cu4Energy)

Date du début: 1 mai 2015, Date de fin: 30 avr. 2020,

Water oxidation (WO) and oxygen reduction (OR) are crucial reactions to produce and to consume solar fuels. It is important that WO and OR occur with very high catalytic rates with only a very small thermodynamic driving force (i.e. a small overpotential). In these terms, natural catalysts perform significantly better than the artificial systems. Especially the copper enzyme Laccase operates fast ...
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 1

 TERMINÉ 
Immune therapies are therefore currently being pursued to reinvigorate the immune reaction against tumours. This is not trivial, as the right type of immune cells must be activated against a tumour-specific antigen. One method to achieve this is by targeting tumour antigens to certain cross-presentation-promoting receptors on antigen presenting cells. The most intriguing of these is the mannose re ...
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 1

 TERMINÉ 

Zoonotic Anticipation and Preparedness Initiative (ZAPI)

Date du début: 1 mars 2015, Date de fin: 29 févr. 2020,

Emerging infectious diseases are occurring at increasing frequency in Europe and other regions of the world, having profound impacts on public and/or veterinary health as well as disruptive effects on sector, regional or even global economy. The predominantly zoonotic nature of emerging pathogens calls for a One Health approach uniting the human medical and veterinary fields, dedicated to swiftly ...
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 21

 TERMINÉ 
The basic concept of our proposal is to develop nanoparticle-based encapsulated libraries of different immunotherapeutic biomolecules for treatment after surgery as part of a novel cancer management strategy. The current state-of-art for the management of cancer starts with surgery, after identification of an accessible tumour mass. Surgery remains an effective treatment option for many types of c ...
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 14

 TERMINÉ 
Stem cell regenerative therapies hold great promise for patients suffering from a variety of disorders that are associated with tissue or organ injury. Regeneration relies on tissue or organ-specific stem and progenitor cells, but can also aim at promoting the endogenous repair capacity of the body. Mesenchymal stromal cells (MSC) are undergoing clinical testing in a variety of clinical conditions ...
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 12

 TERMINÉ 

Ethical and Societal Implications of Data Sciences (e-Sides)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

Data-driven innovation is deeply transforming society and the economy. Although there are potentially enormous economic and social benefits this innovation also brings new challenges for individual and collective privacy, security, as well as democracy and participation. The main objective of the CSA e-SIDES is to complement the research on privacy-preserving big data technologies, by analysing, m ...
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 3

 TERMINÉ 

Knowledge in the making in the European society (KNOWMAK)

Date du début: 1 janv. 2017, Date de fin: 31 déc. 2019,

KNOWMAK project aims at developing a web-based tool, which provides interactive visualisations and state-of-the-art indicators on knowledge co-creation in the European Research Area (ERA). It is structured around three integrative elements:• Research topics, by developing ontologies around Societal Grand Challenges and Key Enabling Technologies.• Actors, with a focus on the quadruple helix and the ...
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 7

 TERMINÉ 

MULTIscale SENTINEL land surface information retrieval PLatform (MULTIPLY)

Date du début: 1 janv. 2016, Date de fin: 31 déc. 2019,

With the start of the SENTINEL era, an unprecedented amount of Earth Observation (EO) data will become available. Currently there is no consistent but extendible and adaptable framework to integrate observations from different sensors in order to obtain the best possible estimate of the land surface state. MULTIPY proposes a solution to this challenge. The project will develop an efficient and ful ...
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 9

 TERMINÉ 

Systems Medicine of Mitochondrial Parkinson’s Disease (SysMedPD)

Date du début: 1 déc. 2015, Date de fin: 30 nov. 2019,

The overall objective of this project is to identify novel drug candidates capable of slowing down the progression of neurodegeneration in the subset of Parkinson’s disease (PD) patients with overt mitochondrial dysfunction. Multi-modal phenotypic characterisation of cohorts of monogenic PD patients with overt mitochondrial dysfunction will be used as an anchor for the discovery of two extreme coh ...
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 8

 TERMINÉ 
GLYCOVAX is a network for the education of promising young scientists who will learn how to rationally design a next generation of well-defined and innovative glycoconjugate vaccines to improve current preventive therapies and to tackle unmet medical needs. Glycoconjugate vaccines represent the key for success of vaccination in children. The covalent linkage to proteins renders carbohydrates able ...
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 12

 TERMINÉ 

Quantum Computer Lab (QC-LAB)

Date du début: 1 nov. 2013, Date de fin: 31 oct. 2019,

The world of atoms is governed by the rules of quantum mechanics. Over the past century, quantum-mechanical phenomena such as superposition and entanglement have been observed and studied with great precision. Today, we are entering a new era in which we can hope to explore quantum mechanics in larger objects. The science of quantum mechanics in more complex objects is barely known and as a result ...
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 2

 TERMINÉ 

Boosting Engagement of Serbian Universities in Open Science

Date du début: 15 oct. 2016, Date de fin: 14 oct. 2019,

Open science provides an effective framework for the enhancement of research transparency, dissemination, collaborations, and accountability. Serbian academic community have recognized the importance and advantages of open science principles which is manifested through the numerous initiatives undertaken by the government bodies, faculties, libraries, NGOs, and journal publishers. However, in the ...
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 11

 TERMINÉ 

Infrastructure for NMR, EM and X-rays for translational research (iNEXT)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

Structural biology provides insight into the molecular architecture of cells up to atomic resolution, revealing the biological mechanisms that are fundamental to life. It is thus key to many innovations in chemistry, biotechnology and medicine such as engineered enzymes, new potent drugs, innovative vaccines and novel biomaterials.iNEXT (infrastructure for NMR, EM and X-rays for Translational rese ...
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 23

 TERMINÉ 

NEXUS 1492. New World Encounters in a Globalising World (NEXUS1492)

Date du début: 1 sept. 2013, Date de fin: 31 août 2019,

NEXUS1492 investigates the impacts of colonial encounters in the Caribbean, the nexus of the first interactions between the New and the Old World. This Synergy Programme intends to rewrite a crucial and neglected chapter in global history initiated by European colonisation by focussing on transformations to indigenous, Amerindian cultures and societies. NEXUS1492 will address intercultural Amerind ...
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 3

 TERMINÉ 

EUROPLANET 2020 Research Infrastructure (EPN2020-RI)

Date du début: 1 sept. 2015, Date de fin: 31 août 2019,

The Europlanet 2020 Research Infrastructure (EPN2020-RI) will address key scientific and technological challenges facing modern planetary science by providing open access to state-of-the-art research data, models and facilities across the European Research Area. Its Transnational Access activities will provide access to world-leading laboratory facilities that simulate conditions found on planetar ...
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 35

 TERMINÉ 
In modern societies, the criminal justice system is entrusted to punish norm violators in a fair and impartial way. Yet, punishment judgments are subject to biases, and are sometimes shaped by extralegal factors, as illustrated for example by the over-representation of African-Americans in inmates in the US. This project investigates one such factor, namely perceived threats to one’s personal valu ...
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 1