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 EN COURS 
The INFRAFRONTIER RI integrates European Mouse Clinics and the European Mouse Mutant Archive with the common goal to ensure access to mouse models for basic research of human health and disease, and to translate this knowledge into therapeutic approaches for the benefit of the European society. The expanded INFRAFRONTIER2020 network, coordinated by the INFRAFRONTIER GmbH, includes 3 SMEs and is st ...
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 TERMINÉ 
The IPAD-MD project addresses cooperation and coordination between the pan-European INFRAFRONTIER Research Infrastructure and complementary research infrastructures in America, Asia and Australia, contributing to the global effort of the International Mouse Phenotyping Consortium (IMPC). In order to increase the reach of INFRAFRONTIER, IPAD-MD will also reach out to complementary infrastructures a ...
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 TERMINÉ 
The mouse shows great similarities in development, physiology and biochemistry to humans, which makes it a key model for research into human disease. The major challenges for mouse functional genomics in the 21st century are to:• Develop a series of mutant alleles for every gene in the mouse genome• Determine the phenotypic consequences of each mutation• Identify mouse models for the complete dise ...
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 TERMINÉ 
InfraCoMP will establish efficient coordination mechanisms between the ESFRI project Infrafrontier and the International Mouse Phenotyping Consortium. Infrafrontier is a pan-European initative to build a sustainable research infrastructure for systemic phenotyping, archiving and distribution of mouse models of human diseases. The IMPC is a global project to carry out systemic phenotyping of mouse ...
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 TERMINÉ 
Medically related Life Sciences use the mouse as a model system to understand the molecular basis of health and disease in humans (>95% similarity of genes in humans and mice). An essential task for Biomedical Sciences in the 21st century will be the functional analysis of mouse models for every gene in the mammalian genome. The major bottlenecks identified by the user community will be proper ...
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