Date du début: 1 janv. 2017,
Date de fin: 31 déc. 2020,
Molecular in vitro diagnostics and biomedical research have allowed great progress in personalised medicine but further progress is limited by insufficient guidelines for pre-analytical workflow steps (sample collection, preservation, storage, transport, processing etc.) as well as by insufficient quality assurance of diagnostic practice. This allows using compromised patients’ samples with post c ...
Date du début: 1 févr. 2016,
Date de fin: 31 janv. 2020,
Sepsis is a potentially fatal condition that arises when the body’s response to an infection damages its own tissues and organs. It is mainly caused by bacteria and fungi, which spread through the blood circulation. It is one of the biggest public health issue in the EU and worldwide due to its high incidence, mortality, human and economic cost. Early diagnosis is crucial to the management of seps ...
Date du début: 1 janv. 2015,
Date de fin: 31 déc. 2019,
...n clinical trials, 5 SMEs with unique technologies for CTC isolation (Vycap, Leukocare, Gilupi) or for creation of databases, analysis of complex molecular information and data management (Alacris, TATAA) and two non-profit organizations (IBBL, a Biobank with extensive experience in the validation and execution of plasma assays; EORTC, the European organization that aims to develop, conduct, coord ...
Date du début: 1 févr. 2013,
Date de fin: 31 janv. 2019,
As more people survive into old age, the prevalence of heart failure (HF), one of the most common and debilitating diseases in older people, will rise still further. Delaying or preventing HF will have great benefit to those at personal risk, their families, society and the economy. HOMAGE aims to provide a biomarker (BM) approach that will a) help identify i. patients at high risk of developing ...
Date du début: 1 mars 2013,
Date de fin: 28 févr. 2017,
"Despite the past century witnessing considerable advances in our understanding of genetics, the success of genome-wide association studies (GWAS) in detecting putative causal variants has been tinged with disappointment as the effects found have been modest. Epigenetics promises a novel biological foundation of a new way of looking at common diseases because it responds to the environment and gov ...
Date du début: 1 févr. 2012,
Date de fin: 31 janv. 2015,
"Developmental plasticity modulated by epigenetic processes such as methylation and post-translational modifications is influenced by early life events and determines risk of age related diseases later in lifeWe propose a multi-disciplinary approach incorporating biochemistry, genetics, epidemiology, epigenetics and bioinformatics to discover novel biomarkers of ageing and interventional pathways ...
Date du début: 15 sept. 2009,
Date de fin: 14 sept. 2013,
It became evident over the last 20 years that glial cells are involved in virtually every aspect of nervous system function. Neurons and glia exchange chemical signals that are essential for the normal function of the nervous system, and are crucial in disease. Recently it was discovered that glial cells also act as neural stem cells both in early development and adulthood, and in synapse formatio ...
Date du début: 1 oct. 2008,
Date de fin: 31 mars 2013,
"In vitro diagnostics have allowed a great deal of progress in medicine but are limited by two factors: (a) the lack of guidelines in collection, handling, stabilisation and storage of biosamples which limits the reproducibility of subsequent diagnoses, and (b) its scale is restrained to the cellular level. To address this first point, this IP, SPIDIA, built of clinicians, academics, tool and assa ...
Date du début: 1 mai 2008,
Date de fin: 28 févr. 2013,
Conventional analytical methods often require a large sample volume and complicated time-consuming protocols. The objective of this project is to develop ultra low cost laboratories on chips (LOC) without penalisation in time response, sensitivity or simplicity of use. The user will obtain the test results using a very popular interface (a smartphone) and a set of Labcards and Skin Patches where t ...
Date du début: 1 févr. 2008,
Date de fin: 31 juil. 2012,
The overall concept of the CD-MEDICS IP is to develop a technology platform for point-of-care diagnostics, capable of simultaneous genomic and proteomic detection, with embedded communication abilities for direct interfacing with hospital information systems. This will be achieved by exploiting breakthroughs at the confluences of bio-, micro- and nano- technologies to create a low-cost non-invasiv ...
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